Bizarre Patents
Mouse device with a built-in printer
A mouse device for use as an input device of a computer is provided that includes a housing in which recording paper is loadable, and a printer unit provided within the housing for printing on the recording paper print information received from the computer.
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| Number | Title | Issue Date |
| 8168647 | Vinblastine derivatives, their preparation, use and pharmaceutical compositions comprising the said derivatives The invention provides vinblastine derivatives represented by the following formula 1 or their physiologically acceptable salts, their preparation, use and pharmaceutical compositions comprising the said derivatives. The said vinblastine derivatives show inhibiting ... | 05/01/2012 |
| 7652025 | Remedies for sepsis A therapeutic agent for sepsis and various symptoms accompanying sepsis (such as septic shock, disseminated intravascular coagulation syndrome, adult respiratory distress syndrome and multiple organ dysfunction) is disclosed. The therapeutic agent for sepsis accordi... | 01/26/2010 |
| 7407939 | Protein kinase inhibitors comprising ATP mimetics conjugated to peptides or peptidomimetics The present invention provides small molecules having high affinity to the ATP binding site of protein kinases, which are conjugated to apeptide or peptidomimetic moiety which mimics the substrate of PKB. The chimeric compounds according to the present invention pre... | 08/05/2008 |
| 7291731 | N-aryl diazaspiracyclic compounds and methods of preparation and use thereof Compounds, pharmaceutical compositions including the compounds, and methods of preparation and use thereof are disclosed. The compounds are N-aryl diazaspirocyclic compounds, bridged analogs of N-heteroaryl diazaspirocyclic compounds, or prodrugs or metabolites of t... | 11/06/2007 |
| 7271173 | Mixed opioids and uses thereof This invention features opioid compounds having activity at kappa and mu receptors, methods for preparing the mu/kappa opioids, and methods for the treatment of pain or a dopamine dysregulation disease, such as schizophrenia, attention deficit hyperactivity disorder... | 09/18/2007 |
| 7229772 | Detection of apoptotic products The present invention concerns a method for the determination of apoptotic products in samples taken from patients in which apoptosis is induced as a result of disease or therapy, which is characterized in that the concentration of the apoptotic products in samples ... | 06/12/2007 |
| 7226991 | Phenylalanine derivatives Disclosed herein are phenylalanine derivative compounds of the following formula W—Y—(AA)n—Z wherein Y is a phenylalanyl radical, AA is an amino acid, n is an integer of 1 to 15, and substituent variables W and Z are as described... | 06/05/2007 |
| 7141582 | Method for enhancing mutant enzyme activities in Gaucher disease Method for enhancing in a mammalian cell the activity of an enzyme associated with Gaucher Disease by administering a competitive inhibitor of glucocerebrosidase in an amount effective to enhance the activity of the enzyme. Preferred compounds for use in the method ... | 11/28/2006 |
| 6972287 | Method of inhibiting amyloid protein aggregation and imaging amyloid deposits The present invention provides a method of treating Alzheimer's disease using a compound of Formula (I). Also provided is a method of inhibiting the aggregation of amyloid proteins using a compound of the Formula (I) and a method of imaging amyloid deposits, as well... | 12/06/2005 |
| 6916829 | Method for enhancing mutant enzyme activity in gaucher disease Method for enhancing in a mammalian cell the activity of an enzyme associated with Gaucher Disease by administering a competitive inhibitor of glucocerebrosidase in an amount effective to enhance the activity of the enzyme. Preferred compounds for use in the method ... | 07/12/2005 |
| 6774135 | Method of enhancing lysosomal α-galactosidase A A method of enhancing the activity of lysosomal α-Galactosidase A (α-Gal A) in mammalian cells and for treatment of Fabry disease by administration of 1-deoxy-galactonojirimycin and related compounds. ... | 08/10/2004 |
| 6740641 | Sugar derivatives of hydromorphone, dihydromorphine and dihydromorphine, compositions thereof and uses for treating or preventing pain Glucoside and glucuronide derivatives of hydromorphone, dihydromorphine, and dihydroisomorphine and pharmaceutically acceptable salts thereof; pharmaceutical compositions comprising a glucoside or glucuronide derivative of hydromorphone, dihydromorphine, or dihydroi... | 05/25/2004 |
| 6602881 | Anti-inflammatory uses of manzamines The subject invention pertains to compounds which are useful as anti-inflammatory agents and to compositions containing such compounds as active ingredients. The novel uses of the compounds relate to the anti-neurogenic inflammatory properties of the disc... | 08/05/2003 |
| 6583158 | Method for enhancing mutant enzyme activities in lysosomal storage disorders Method for enhancing in a mammalian cell the activity of an enzyme associated with a lysosomal storage disorder by administering a competitive inhibitor of the enzyme in an amount effective to enhance the activity of the enzyme. Preferred compounds for us... | 06/24/2003 |
| 6569866 | Sustained-release nalmefene preparations and method A nalmefene transdermal delivery system useful for the treatment of human patients suffering from opioid addiction.... | 05/27/2003 |
| 6528519 | Use of tetrandrine and its derivatives to treat malaria The specification discloses the treatment of malaria through the use of tetrandrine and its derivatives.... | 03/04/2003 |
| 6482837 | Antimuscarinic compounds and methods for treatment of bladder diseases Compositions comprising antimuscarinic compounds that have been modified to render them substantially irreversible, such as by quaternization of the heterocyclic ring nitrogen, have improved properties when administered intravesically for treatment of bla... | 11/19/2002 |
| 6410550 | Aryl fused azapolycyclic compounds Compounds of the formula ##STR1## and their pharmaceutically acceptable salts, wherein R1, R2, and R3 are defined as in the specification, intermediates in the synthesis of such compounds. pharmaceutical compositions conta... | 06/25/2002 |
| 6387916 | Anti-inflammatory uses of manzamines The subject invention pertains to compounds which are useful as anti-inflammatory agents and to compositions containing such compounds as active ingredients. The novel uses of the compounds relate to the anti-neurogenic inflammatory properties of the disc... | 05/14/2002 |
| 6365594 | Heterocycle-condensed morphinoid derivatives (II) Heterocycle-condensed morphinoid derivatives of formula (I), or solvates or salts thereof, ##STR1## are potent and selective delta opioid agonists and antagonists and are useful as i.a. analgesics. Pharmaceutical compositions containing such compound... | 04/02/2002 |
| 6350755 | Inhibitors of prenyl-protein transferase The present invention is directed to peptidomimetic macrocyclic compounds which inhibit prenyl-protein transferase and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds... | 02/26/2002 |
| 6271240 | Methods for improved regulation of endogenous dopamine in prolonged treatment of opioid addicted individuals Methods for optimally regulating dopamine homeostasis in persons addicted to, then chemically detoxified from, opioid agonist analgesics, which generally include prolonged controlled administration of nalmefene, with or without the addition of a centrally... | 08/07/2001 |
| 6174891 | Antipruritic agent This invention provides an antipruritic comprising an opiate .kappa. receptor agonist as an effective component, a new morphinan quaternary ammonium salt derivative and a new morphinan-N-oxide derivative which are useful in treating pruritus complicated w... | 01/16/2001 |
| 6143756 | Antimalarial activity of ଲ-carboline alkaloids Manzamines, administered either intraperitoneally or orally, have been found to prolong survival and inhibit parasitemia in erythrocytic stage malaria. Thus, manzamines can be used for both prophylaxis and treatment. Manzamine A is a preferred compound fo... | 11/07/2000 |
| 6124310 | Enediyne compounds The present invention provides compounds of formulae (I) and (II), where X in formula (I) represents a group cleavable by a nitroreductase or carboxypeptidase enzyme. Enzymatic activation of the compounds provide pharmaceutical compounds which may be used... | 09/26/2000 |
| 6030980 | Agent for the treatment of infections The present invention relates an agent for the treatment of infections, which comprises as the active ingredient at least one member selected from the group consisting of aconite-alkaloids, aconite tuber and an extract thereof, gingerol and analogues ther... | 02/29/2000 |
| 5985887 | Aza-anthracyclinone derivatives Compounds of formula I ##STR1## wherein X1 and X2 are C.dbd.O, C.dbd.NH or CH2, X3 is CH2, CO, CHOH, ##STR2## wherein n=2 or, 3 or C.dbd.N(R9) wherein R9 is hydroxy or ... | 11/16/1999 |
| 5981540 | Heterocycle-condensed morphinoid derivatives Compounds of formula (I), are selective delta opioid agonsist and antagonists, and are useful as analgesics and in treating general neurologic disorders. ##STR1##... | 11/09/1999 |
| 5972993 | Composition and method for treating rosacea and sensitive skin with free radical scavengers A method for treating skin conditions, such as rosacea and sensitive skin, that manifest as a tendency towards flushing and blushing is provided. Also provided herein, are compositions for the treatment of rosacea and sensitive skin that are comprised of ... | 10/26/1999 |
| 5919760 | Method for treating acute and severe diarrhea The invention provides a method for treating acute and severe diarrhea such as that which accompanies chemotherapy and rapid narcotic detoxification. The method includes administering octreotide in an amount sufficient to alleviate the diarrhea without pr... | 07/06/1999 |
| 5843952 | Tricyclic benzazepine vasopressin antagonists Tricyclic compounds of the general Formula I: ##STR1## as defined herein which exhibit antagonist activity at V1 and/or V2 receptors and exhibit in vivo vasopressin antagonist activity, methods for using such compounds in treati... | 12/01/1998 |
| 5783583 | 17-(cyclopropylmethyl)-4,5alpha-epoxy-6-methylenemorphinan-3,14-diol, hydrochloride salt for the purpose of rapid narcotic detoxification Methods whereby the narcotic antagonist 17-(cyclopropylmethyl)-4,5alpha-6-methylenemorphinan-3,14-diol,hydrochlori de salt and other narcotic antagonists are used for chemically precipitating a withdrawal response in human beings addicted to exogenous ... | 07/21/1998 |
| 5744476 | Dopamine D1 agonists for the treatment of dementia This invention provides for a method of raising extracellular brain acetylcholine levels to improve cognition by the administration to a warm-blooded animal of a pharmaceutical composition comprising an effective amount of a dopamine D1 agonist... | 04/28/1998 |
| 5648359 | Tumor necrosis factor production inhibitors There is provided a composition for inhibiting the production or secretion of tumor necrosis factor effective for the treatment of cachexia, septic shock, multiple organ failure, rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis, osteoa... | 07/15/1997 |
| 5631264 | Substituted 6,11-ethano-6,11-dihydrobenzo[B]quinolizinium salts and compositions and methods of use thereof Substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts, pharmaceutical compositions containing them, and methods for the treatment or prevention of neurodegenerative disorders or neurotoxic injuries utilizing them.... | 05/20/1997 |
| 5569456 | Biologically active rupununines A rupununine, either in purified form or a derivative in which one or both of the hydroxyl groups is substituted, the rupununine having the formula: ##STR1## where R.dbd.--H or --CH3.... | 10/29/1996 |
| 5554620 | Substituted 6,11-ethano-6,11-dihydrobenzo[b] quinolizinium salts and compositions and methods of use thereof Substituted 6,11-ethano-6,11-dihydrobenzo[b]quinolizinium salts, pharmaceutical compositions containing them, and methods for the treatment of neurodegenerative disorders or neurotoxic injuries utilizing them, wherein the substituted 6,11-ethano-6,11-dihy... | 09/10/1996 |
| 5512577 | Bicyclic hexahydroaporphine and 1-benzyloctahydroisoquinoline therapeutic compositions and processes for utilizing said compositions The invention relates to the method of synthesis of bicyclic hexahydroaporphine compounds which may provide improved therapy for diseases characterized by an increase in intraocular pressure. More specifically, the present invention relates to the prepara... | 04/30/1996 |
| 5500432 | Induction and inhibition of apoptosis A method for inducing apoptosis in target cells employs designed enediynes which are triggered to become chemically reactive when bound to target cells. Conversely, a method for inhibiting the induction of apoptosis employs compounds which compete with th... | 03/19/1996 |
| 5492925 | Thienyl-and furylpyrrole insecticidal and acaricidal agents There are provided thienyl- and furylpyrrole compounds of formula I ##STR1## and their use for the control of insects and acarina. Further provided are compositions and methods comprising those compounds for the protection of plants from attack by in... | 02/20/1996 |
