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| Number | Title | Issue Date |
| 8168597 | Method for treating cystic fibrosis The present invention is directed to a method for treating cystic fibrosis. The method comprises the steps of: identifying a patient suffering from cystic fibrosis, and administering to the patient an effective amount of denufosol or a pharmaceutically acceptable sa... | 05/01/2012 |
| 8133871 | Dihydropseudoerythromycin derivatives A compound represented by the formula [I] wherein each symbol is as defined in the specification or a pharmacologically acceptable salt thereof, and a pharmaceutical composition containing the compound as an active ingredient. ... | 03/13/2012 |
| 8003616 | Composition for the treatment of ear infections and method A composition for treating ear infections in animals includes an antifungal agent, an antibiotic agent, a steroidal anti-inflammatory agent, and an acid dissolved to form a liquid. The acid aids in keeping the steroidal anti-inflammatory agent in solution, and enhan... | 08/23/2011 |
| 7960354 | Synergistic pesticidal mixtures Synergistic pesticidal mixtures are provided. ... | 06/14/2011 |
| 7943585 | Extended release antibiotic composition An extended-release antibiotic composition comprising at least one antibiotic, and greater than 50 weight percent, based on the total weight of the composition, of a polymer component, wherein said polymer component comprises at least one pharmaceutically acceptable... | 05/17/2011 |
| 7910558 | Bridged macrocyclic compounds and processes for the preparation thereof The present invention provides a method for preparing bridged macrocyclic compounds comprising the step of reacting a macrocyclic compound characterized by having at least two nucleophilic moieties with a bifunctional bridging reagent optionally in the presence of a... | 03/22/2011 |
| 7906489 | 18-membered macrocycles and analogs thereof The present invention relates generally to the 18-membered macrocyclic antimicrobial agents called Tiacumicins, specifically, OPT-80 (which is composed almost entirely of the R-Tiacumicin B), pharmaceutical compositions comprising OPT-80, and methods using OPT-80. I... | 03/15/2011 |
| 7879809 | Fish production This invention is directed to the use of spinosyn or a physiologically acceptable derivative or salt thereof for improved production of fish; controlling ectoparasite infestations in aquaculture raised fish; and fish feed formulations. ... | 02/01/2011 |
| 7875593 | Fungicidal agent combinations The invention relates to novel fungicidally active compound combinations of 2′-cyano-3,4-dichloroisothiazole-5-carboxanilide of the formula and active compounds listed in the disclosure. ... | 01/25/2011 |
| 7863249 | Macrolide polymorphs, compositions comprising such polymorphs, and methods of use and manufacture thereof The invention relates to novel forms of compounds displaying broad spectrum antibiotic activity, especially crystalline polymorphic forms and amorphous forms of such compounds, compositions comprising such crystalline polymorphic forms and amorphous forms of such co... | 01/04/2011 |
| 7795231 | Concentrated aqueous azalide formulations The present invention relates to formulations of concentrated azalide antibiotics and methods for making and using them. Specifically, the invention relates to a method of treating an infection comprising administering to a patient in need thereof, an effective amou... | 09/14/2010 |
| 7737122 | Spinosyn fumigants Methods of controlling arthropod pests by dispersing spinosyn compositions in the form of aerosols, fogs, smokes, or vapors are disclosed. ... | 06/15/2010 |
| 7713940 | Water-soluble isoflavone composition, process for producing the same, and use thereof An isoflavone composition which contains an α-glucosyl isoflavone and isoflavone and optionally an isoflavone aglycone, wherein the ratio of the amount of aglycone in the isoflavone and the isoflavone aglycone in total to the amount of aglycone in the α-glucosyl i... | 05/11/2010 |
| 7709447 | Use of spinosyns for wound healing A spinosyn or a physiologically acceptable derivative or salt thereof for promoting or accelerating wound healing in humans. ... | 05/04/2010 |
| 7608595 | 4″-deoxy-4″-(S)-amido avermectin derivatives A compound of formula (I); that has the S-configuration at the 4″-position and wherein the bond between carbon atoms 22 and 23 is a single or a double bond; R1 is C1-C12alkyl, C3-C8cycloalkyl; or C2... | 10/27/2009 |
| 7381744 | Method of treating osteoporosis comprising vacuolar-type (H+)-ATPase-inhibiting compounds The present invention provides vacuolar-type (H+)-ATPase-inhibiting compounds, compositions thereof, and methods of using them to treat or prevent a condition treatable by the inhibition of a vacuolar-type (H+)-ATPase. The composition of the present invention compri... | 06/03/2008 |
| 7358232 | Method for the antibiotic coating of bodies with interconnecting microcavities as well as coated bodies and their usage The invention relates to a method for the antibiotic coating of bodies with interconnecting microcavities as well as bodies coated this way and their usage. The invented method is characterized in that in the microcavities of non-metallic bodies an aqueous solution ... | 04/15/2008 |
| 7358233 | Tetronic acid derivative The present inventors intended to search for substances that can regulate the expression of a molecular chaperone, GRP78, using the expression of GRP78 as an indicator. As a result, a novel tetronic acid derivative, versipelostatin compound (also known as JL68) show... | 04/15/2008 |
| 7349857 | Process for formulating a customized skin care product The invention relates to a method and a process of determining individual skin structure and function at a point in time for the purpose of determining and formulating skin care products that remedy the deficiencies observed in the skin. Objective and repeatable der... | 03/25/2008 |
| 7335753 | Bifunctional heterocyclic compounds and methods of making and using same The invention provides a family of bifunctional heterocyclic compounds useful as anti-infective, anti-proliferative, anti-inflammatory, and prokinetic agents. The invention also provides methods of making the bifunctional heterocyclic compounds, and methods of using... | 02/26/2008 |
| 7323452 | Method for the accelerated in vivo removal of ethanol A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as catalysts or “pseudo” enzymes for the oxidation. These additives... | 01/29/2008 |
| 7312200 | 9-ketospinosyn derivatives The present invention relates to derivatives of 9-keto spinosyns, which are substituted by a ═N—(O, NH or NRx)—Ry moiety in the C-9 position, to methods for their manufacture, and to their use for controlling animal pests. ... | 12/25/2007 |
| 7303772 | Synergistic phytoceutical compositions Phytoceutical compositions for the prevention and treatment of circulatory disorders, feminine endocrine disorders, and dermal disorders. A specific combination of extracts of plants is taught, as well as principles for varying the formulations based on categorizing... | 12/04/2007 |
| 7285653 | Nucleic acids which code for the enzyme activities of the spinosyn biosynthesis The present invention relates to nucleic acid coding for enzyme activities of spinosyn biosynthesis and to the relevant enzymes per se. Furthermore, the invention relates to methods for preparing spinsoyn derivatives and spinosyn precursors. ... | 10/23/2007 |
| 7256178 | Physiologically active substances Compounds represented by the following general formula (I), pharmacologically acceptable salts thereof or hydrates of the same: (I) wherein W represents and R3, R7, R16, R17 | 08/14/2007 |
| 7223799 | Color-developing composition and cosmetic, fragrance products and miscellaneous goods for display with the use of the same The invention provides a color-developing composition without using a pigment or dye and capable of being colored sustainably and stably after mixing two liquid phases which are colorless before mixing. The composition consists of two discrete liquid phases, wherein... | 05/29/2007 |
| 7214759 | Biologically absorbable coatings for implantable devices based on polyesters and methods for fabricating the same Polymers containing polyesters and, optionally, agents for use with medical articles and methods of fabricating the same are disclosed. The medical article generally comprises an implantable substrate having a coating, and the coating contains a polymer comprising a... | 05/08/2007 |
| 7205001 | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds The invention relates to the use of arsenic compounds to treat a variety of neoplastic diseases. The present invention encompasses the administration to a mammal of arsenic in the form of a salt, complex, organic compound or ionic solution to treat tumors of epithel... | 04/17/2007 |
| 7195773 | Pesticidal composition A pesticidal composition comprising a pesticidally effective amount of at least one of a pyridic compound of the formula (I) or it salt and at least one of other pesticides: wherein Y is a haloalkyl group, m is 0 or 1, and Q is or a substituted or unsubstituted hete... | 03/27/2007 |
| 7179493 | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds The invention relates to the use of arsenic compounds to treat a variety of neoplastic diseases. The present invention encompasses the administration to a mammal of arsenic in the form of a salt, complex, organic compound or ionic solution to treat tumors of epithel... | 02/20/2007 |
| 7176185 | Short peptide carrier system for cellular delivery of agent A dipeptide or tripeptide carrier system for active agent delivery to cells has an N-terminus natural amino acid and an active agent covalently bonded to a side chain of one of the remaining amino acid bases. The system is amenable to formulation as an oral administ... | 02/13/2007 |
| 7163703 | Compositions and methods for the treatment of primary and metastatic neoplastic diseases using arsenic compounds The invention relates to the use of arsenic compounds to treat a variety of neoplastic diseases. The present invention encompasses the administration to a mammal of arsenic in the form of a salt, complex, organic compound or ionic solution to treat tumors of epithel... | 01/16/2007 |
| 7160867 | Rapamycin carbohydrate derivatives This invention provides modified rapamycins that have specific monosaccharide(s), oligosaccharide(s), pseudosugar(s) or derivatives thereof attached through a linker to create rapamycin carbohydrate derivatives having enhanced pharmacokinetic and/or pharmacodynamic ... | 01/09/2007 |
| 7153877 | Method and composition for preventing or reducing the symptoms of insulin resistance syndrome A method for preventing and or reducing the symptoms of insulin resistance and a related syndrome in persons comprises identifying persons having or at risk for having such symptoms, and administering to them an effective amount of a composition comprising niacin-bo... | 12/26/2006 |
| 7151116 | Apoptolidin analogs and derivatives for inducing apoptosis in transformed cells The invention provides novel apoptosis-inducing compounds that include isolated, purified isoapoptolidin, and selectively functionalized isoapoptolidin derivatives and stereoisomers thereof; selectively functionalized apoptolidin derivatives and stereoisomers thereo... | 12/19/2006 |
| 7144866 | Avermectin derivatives Provided is a compound represented by the general formula (I) or a salt thereof: wherein, —XY— represents —CH═CH— and the like, between R2 and the carbon atom at 5-posi... | 12/05/2006 |
| 7141582 | Method for enhancing mutant enzyme activities in Gaucher disease Method for enhancing in a mammalian cell the activity of an enzyme associated with Gaucher Disease by administering a competitive inhibitor of glucocerebrosidase in an amount effective to enhance the activity of the enzyme. Preferred compounds for use in the method ... | 11/28/2006 |
| 7129221 | 6,11-bicyclic erythromycin derivatives The present invention discloses compounds of formula I, or pharmaceutically acceptable salts, esters, or prodrugs thereof: which exhibit antibacterial properties. The present invention further relates to pharmace... | 10/31/2006 |
| 7119110 | Method and composition for preventing or reducing the symptoms of insulin resistance syndrome A method for preventing and or reducing the symptoms of insulin resistance and a related syndrome in persons comprises identifying persons having or at risk for having such symptoms, and administering to them an effective amount of a composition comprising niacin-bo... | 10/10/2006 |
| 7119124 | Pharmaceutical compositions containing plasma protein The invention is related to water-soluble products and pharmaceutical formulations in solid or liquid form mainly for parenteral use. They consist of or comprise a therapeutically active substance (having low aqueous solubility and a substantial binding affinity to ... | 10/10/2006 |
