Method and apparatus for making a drink hop along a bar or counter
A method for generating a drink which appears to hop from a remote spot on the bar or counter and take one or more leaps, before landing in a patron's glass.
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| Number | Title | Issue Date |
| 8158644 | Pharmaceutical compositions comprising polymorphic forms α, β, and γ of rifaximin Crystalline polymorphous forms of rifaximin (INN), referred to as rifaximin α and rifaximin β, and a poorly crystalline form referred to as rifaximin γ, useful in the production of medicaments containing rifaximin for oral and topical use and obtained by means of... | 04/17/2012 |
| 8153647 | Aryl- and heteroaryl-ethyl-acylguanidine derivatives, their preparation and their application in therapeutics Disclosed are compounds according to formula (I): wherein A, Q, X, Y, Z, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 are as defined herein. The disclosure also relates to pharmaceutical compositions containing a compoun... | 04/10/2012 |
| 8119653 | Belactosin derivatives as therapeutic agents/biological probes and their synthesis Derivatives of belactosin and their synthesis are disclosed. In certain embodiments, compounds of the present invention exhibit anti-cancer, antiviral, antibiotic, and/or auto-immune therapeutic abilities. In general, methods of synthesis disclosed herein allow for ... | 02/21/2012 |
| 8110582 | Prophylactic treatment of UV-induced epidermal neoplasia The present invention provides a method of protecting a subject against UV-induced epidermal neoplasia. Generally, the method includes administering to a subject an IRM compound in an amount effective to provide protection against UV-induced epidermal neoplasia. The... | 02/07/2012 |
| 8088786 | Layered pharmaceutical formulations In one embodiment a layered pharmaceutical formulation includes two or more pharmaceutical layers and an intermediate layer disposed between at least two of the two or more pharmaceutical layers, the intermediate layer configured to dissolve in vivo to thereby leave... | 01/03/2012 |
| 8076351 | Camptothecin derivatives with antitumor activity Novel camptothecin derivatives having antitumor activity, the processes for the preparation thereof, the use thereof as antitumor drugs and pharmaceutical compositions containing them. ... | 12/13/2011 |
| 8067429 | Forms of rifaximin and uses thereof The present invention relates to Rifaximin polymorphic, salt, hydrate, and amorphous forms, to their use in medicinal preparations and to therapeutic methods using them. ... | 11/29/2011 |
| 8030324 | Pyridine derivatives for the treatment of metabolic disorders related to insulin resistance or hyperglycemia The present invention provides novel compounds represented by the general formula (I): their stereoisomers, pharmaceutically acceptable salts and their pharmaceutically acceptable solvates thereof, which are useful in treat... | 10/04/2011 |
| 7964610 | Buprenorphine derivatives and uses thereof Ester derivatives of the phenolic hydroxyl group of buprenorphine can be used in the treatment of opiate dependency and/or moderate to severe pain. The esters have an enhanced bioavailability, an enhanced duration of action, and a reduced abuse potential. ... | 06/21/2011 |
| 7951817 | Pyridomorphinans, pyridazinomorphinans and use thereof Compounds represented by the formula: wherein R is C1-6 alkyl; C4-6 cycloalkylalkyl; or C3-6 alkenyl; R′ is H or C1-6 alkyl; X is H or OH; Y is alkyl, cycloalkyl, aryl, h... | 05/31/2011 |
| 7932263 | Therapeutic treatment A combination comprising candesartan and rosuvastatin for the prevention or treatment of arteriosclerosis and for the prevention of cardiovascular events is described. ... | 04/26/2011 |
| 7915275 | Use of polymorphic forms of rifaximin for medical preparations The present invention relates to Rifaximin polymorphic forms α, β and γ, to their use in medicinal preparations for the oral or topical route and to therapeutic methods using them. ... | 03/29/2011 |
| 7902206 | Polymorphic forms α, β and γ of rifaximin Crystalline polymorphous forms of rifaximin (INN) antibiotic named rifaximin α and rifaximin β, and a poorly crystalline form named rifaximin γ, useful in the production of medicinal preparations containing rifaximin for oral and topical use and obtained by means... | 03/08/2011 |
| 7893080 | Method of restoring the incretin effect The present invention relates to methods of treating metabolic syndrome, Type 2 diabetes mellitus, atherogenic dyslipidemia and/or obesity. The present invention also relates to methods of restoring the incretin effect, to restoring physiologic control of glucagon l... | 02/22/2011 |
| 7879869 | Drugs for ameliorating postcibal hyperglycemia It is mentioned to provide drugs for ameliorating postcibal hyperglycemia, drugs for inhibiting an increase in blood glucose level and pharmaceutical compositions for preventing or treating diabetes, each containing a pharmaceutically acceptable anion exchange resin... | 02/01/2011 |
| 7858636 | Hexarylene and pentarylene tetracarboxylic acid diimides Rylenetetracarboximides of the general formula I in which the variables are defined as follows: R are identical or different radicals: hydrogen; alkyl, cycloalkyl, aryl or hetaryl, each substituted if desired; | 12/28/2010 |
| 7737158 | Processes for regulating blood glucose in a mammal The present invention relates to processes for regulating the blood glucose concentration of a mammal. ... | 06/15/2010 |
| 7678807 | Isoquinoline and benzo[H] isoquinoline derivatives, preparation and therapeutic use thereof as antagonists of the histamine H3 receptor The invention concerns a compound of formula (I): Wherein A, l, m, n, R1 and R2 are as defined herein. The compounds of this invention are useful as medicaments, particularly, in the treatment of disorders improved by modul... | 03/16/2010 |
| 7674797 | 2-phenoxy- and 2-phenylsulfonamide derivatives with CCR3 antagonistic activity for the treatment of asthma and other inflammatory or immunological disorders The present invention relates to a benzenesulfonamide derivative of formula (I), which is useful as an active ingredient of pharmaceutical preparations. The benzenesulfonamide derivatives of the present invention have CCR3 (CC type chemokine receptor) antagonistic a... | 03/09/2010 |
| 7659281 | HMG-CoA reductase inhibitors Compounds are provided of the following structure are HMG CoA reductase inhibitors and thus are active in inhibiting cholesterol biosynthesis, modulating blood serum lipids, for example, lowering LDL cholesterol and/or increasing HDL cholesterol, and treating hyperl... | 02/09/2010 |
| 7629354 | Use of phanquinone for the treatment of Alzheimer's disease The use of phanquinone for the manufacture of a pharmaceutical composition for the prevention or the treatment of Alzheimer's disease is disclosed. Also methods of treatment or prevention of Alzheimer's disease are disclosed. ... | 12/08/2009 |
| 7601731 | Antimicrobial flush solutions The present invention provides antimicrobial solutions that comprise at least one alcohol, at least one antimicrobial agent and at least one chelator and/or anticoagulant. Also provided are methods for rapidly reducing a microbe or a virus from surfaces including su... | 10/13/2009 |
| 7541364 | Pyridomorphinans, pyridazinomorphinans and use thereof Compounds represented by the formula: wherein R is C1-6 alkyl; C4-6 cycloalkylalkyl; or C3-6 alkenyl; R′ is H or C1-6 alkyl; X is H or OH; Y is alkyl, cycloalkyl, aryl, heteroar... | 06/02/2009 |
| 7534799 | Pyridomorphinans, thienomorphinans and use thereof Compounds represented by the formulae: wherein each of Y, X and R individually is selected from the group consisting of hydrogen, hydroxy, halo, CF3, NO2, CN, NH2, COR1 and CO | 05/19/2009 |
| 7511054 | Transdermally deliverable opioid prodrugs, abuse-resistant compositions and methods of using opioid prodrugs Described herein are opioid prodrugs, methods of making opioid prodrugs, formulations comprising opioid prodrugs, and methods of using opioid prodrugs. One embodiment described herein relates to the transdermal administration of a buprenorphine prodrug in an abuse-r... | 03/31/2009 |
| 7456192 | 3β-amino azabicyclooctane heteroaromatic amid derivatives preparation method and therapeutic uses thereof The invention concerns compounds of general formula 1, wherein: A, B, D and E represent one or two nitrogen atoms, the others being carbon atoms; X represents a S or, a O, thereby forming a bicyclic fused heteroaromatic, such as thieno[2,3-b]pyridine, furo[2,3-b]pyr... | 11/25/2008 |
| 7427629 | Immunostimulatory compositions and methods of stimulating an immune response The present invention provides immunostimulatory compositions that include an immune response modifier portion paired with an antigenic portion. ... | 09/23/2008 |
| 7417050 | Heterocyclic compounds Compounds of formula I: and pharmaceutically-acceptable salts thereof, wherein Ar and R are as defined in the specification, compositions containing such compounds and the use of such compounds and compositions for use in t... | 08/26/2008 |
| 7417049 | Furyl compounds Compounds of formula I: and pharmaceutically-acceptable salts thereof, wherein Ar and R are as defined in the specification, compositions containing such compounds and methods of using such compounds and compositions in the... | 08/26/2008 |
| 7410978 | Once daily dosage forms of trospium A pharmaceutical composition of a pharmaceutically acceptable trospium salt, with upon administration to a human patient generates an average steady state blood levels of trospium with a minimum (Cmin) and maximum (Cmax) blood levels of about 0... | 08/12/2008 |
| 7407939 | Protein kinase inhibitors comprising ATP mimetics conjugated to peptides or peptidomimetics The present invention provides small molecules having high affinity to the ATP binding site of protein kinases, which are conjugated to apeptide or peptidomimetic moiety which mimics the substrate of PKB. The chimeric compounds according to the present invention pre... | 08/05/2008 |
| 7399860 | Manufacture of polyglutamate-therapeutic agent conjugates The invention provides new processes for preparing polyglutamic acid-therapeutic agent conjugates for clinical development and pharmaceutical use, and polyglutamic acid-therapeutic agent conjugates prepared by these processes. ... | 07/15/2008 |
| 7399769 | Aryl-isoxazol-4-yl-imidazo[1,5-a]pyridine derivatives The present invention is concerned with aryl-isoxazol-4-yl-imidazo[1,5-a]pyridine derivatives of formula wherein: R1, R2, and R3 are as defined herein and pharmaceutically acceptab... | 07/15/2008 |
| 7390817 | Combinations of a vanilloid antagonist and an NSAID for the treatment of pain A method of treating conditions associated with pain and alleviating the symptoms associated therewith which comprises administering to a mammal, including man, a vanilloid VR-1 antagonist or a pharmaceutically acceptable derivative thereof and an NSAID or a pharmac... | 06/24/2008 |
| 7384942 | Pyrazine based inhibitors of glycogen synthase kinase 3 New bicyclic based compounds, compositions and methods of inhibiting the activity of glycogen synthase kinase (GSK3) in vitro and of treatment of GSK3 mediated disorders in vivo are provided. The methods, compounds and compositions of the invention may be employed a... | 06/10/2008 |
| 7345051 | Mucin synthesis inhibitors The claimed invention relates to methods of modulating mucin synthesis and the therapeutic application of compounds of Formula II in controlling mucin over-production associated with diseases such as chronic obstructive pulmonary diseases (COPD) including asthma and... | 03/18/2008 |
| 7335659 | Substituted 10-aryl-11-benzo[]fluorenes and 7-aryl-5, 6-dihydro-benzo[]anthracenes for selective effects on estrogen receptors This invention provides a compound, or its possible salt, having the formula, wherein: Re and ′Re are OH, optionally independently etherified or esterified; Z is —CH2CH2— or... | 02/26/2008 |
| 7291628 | Treatment of cocaine abuse using N-substituted derivatives of morphinan The invention is based in part on the discovery that nonselective κ agonists that possess μ receptor-mediated effects in addition to their κ agonist effects can decrease cocaine self-administration more effectively and with fewer undesirable side effects than can... | 11/06/2007 |
| 7291732 | Isomeric fused pyrrolocarbazoles and isoindolones The present invention is directed to novel fused pyrrolocarbazoles and isoindolones, including pharmaceutical compositions, diagnostic kits, assay standards or reagents containing the same, and methods of using the same as therapeutics. The invention is also directe... | 11/06/2007 |
| 7258874 | Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use Controlled release ceramic particles, processes for their preparation, controlled release ceramic particles prepared by such processes, compositions comprising such controlled release ceramic particles and methods of using controlled release ceramic particles are de... | 08/21/2007 |