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| Number | Title | Issue Date |
| 8173608 | Compound having cyclic structure and use thereof The present invention relates to a compound represented by the following formula (1′) wherein R is an aldopyranose residue, R2 is a C2-18 hydrocarbon group optionally having substituent(s), R3 is an ... | 05/08/2012 |
| 8138158 | Compositions and methods for therapy for diseases characterized by defective chloride transport Compositions and methods for therapy of cystic fibrosis, asthma, and other conditions characterized by defective chloride transport are provided. The compositions comprise one or more compounds such as flavones and/or isoflavones, ascorbate and/or derivatives thereo... | 03/20/2012 |
| 8129337 | Compositions comprising epigallocatechin gallate and protein hydrolysate The present invention describes a composition comprising EGCG and a protein hydrolysate. ... | 03/06/2012 |
| 8088745 | Methods for assaying alpha-L-iduronidase enzymatic activity Methods for assaying α-L-iduronidase enzymatic activity and methods for screening newborns for Mucopolysaccharidosis Type-I. ... | 01/03/2012 |
| 8084430 | ENT-kaurene diterpene compound and its derivatives, their preparation and their use Novel ent-kaurene diterpene compound and its derivatives, their preparation methods and their use. ent-Kaurene diterpene in the present invention could be used as desired intermediates for preparing asymmetric organic compounds and medicaments, and could be used as ... | 12/27/2011 |
| 8084431 | Method for inhibiting activation of macrophages, inhibiting formation of osteoclasts, inhibiting function of osteoclasts, and/or activating osteoblasts A method for inhibiting the activation of macrophages, inhibiting the formation of osteoclasts, inhibiting the function of osteoclasts, and/or activating osteoblasts in a mammal is provided. The method comprises the administration of an effective amount of kinsenosi... | 12/27/2011 |
| 8048861 | Pesticidal formulations The present invention relates to an active composition for controlling or eradicating Phthiraptera, Siphonaptera and Acarina Pests, typically in domestic animals, comprising a synergistic combination of at least one A83543 compound and at least one macrocyclic lacto... | 11/01/2011 |
| 8044030 | Antibiotic macrocycle compounds and methods of manufacture and use thereof The invention encompasses an active metabolite of the 18-membered macrocyclic antimicrobial agents, specifically, a metabolite of tiacumicin B and in certain embodiments, R-Tiacumicin B or and its related compounds. In particular, the invention encompasses a compoun... | 10/25/2011 |
| 8017587 | 2-O- (β-D-glucopyranosyl) ascorbic acid, process for its production, and foods and cosmetics containing compositions comprising it The present invention provides a novel ascorbic acid derivative as a provitamin C with improved stability in the body and prolonged life in the body compared to conventionally known 2-O-(α-D-glucopyranosyl)ascorbic acid. The composition comprising the novel ... | 09/13/2011 |
| 8003615 | Stable vitamin B6 derivative A compound represented by the following general formula (I) or a salt thereof: wherein R1 represents a glycosyl group, a phosphate group, or a cyclic phosphate group bound to R2; R2 represen... | 08/23/2011 |
| 7998937 | Flavonoid compound having an antiviral activity The present invention relates to a flavonoid compound having an antiviral activity, more particularly to a flavonoid compound obtained by extracting Houttuynia cordata with methanol and separating/purifying with chromatography, a method for efficient extracti... | 08/16/2011 |
| 7989424 | Glucopyranosyloxypyrazole derivatives and use thereof in medicines The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula: wherein R represents a hydrogen atom, a lower alkyl group or a group forming a prodrug; one of Q and T represents a gr... | 08/02/2011 |
| 7960352 | Anti-cancer activity of . extract and contained triterpene saponin The present invention relates to an Androsace umbellata Merr. extract having anticancer activity and a triterpene saponin compound isolated therefrom, more particularly to an Androsace umbellata (Lour.) Merr. extract, triterpene saponin compounds isola... | 06/14/2011 |
| 7960353 | Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders Novobiocin analogues and pharmaceutical composition containing such compounds useful for the treatment and/or prevention of neurodegenerative disorders and autoimmune disorders. ... | 06/14/2011 |
| 7956040 | Combination of catechin and quercetin for pharmaceutical or dietary use The invention relates to a composition for pharmaceutical or dietary use that possesses antioxidant activity and characterized in that it contains as active principle a combination of catechin quercetin, which exert a synergistic action when combined in mutual molar... | 06/07/2011 |
| 7956041 | Prophylactic and therapeutic agent of diabetes mellitus The invention provides a prophylactic and therapeutic agent of diabetes mellitus, including a combination of an inhibitor of renal glucose reabsorption and a hypoglycemic agent. In accordance with the invention, hyperglycemia after meals, between meals and during fa... | 06/07/2011 |
| 7943583 | 2-O-(β-D-glucopyranosyl) ascorbic acid, process for its production, and foods cosmetics containing compositions comprising it The present invention provides a novel ascorbic acid derivative as a provitamin C with improved stability in the body and prolonged life in the body compared to conventionally known 2-O-(β-D-glucopyranosyl)ascorbic acid. The composition comprising the novel compoun... | 05/17/2011 |
| 7943584 | Medicinal composition containing diabetes remedy A pharmaceutical composition effective for the prophylaxis and treatment of diabetes is provided. This pharmaceutical composition comprises the combination of an α-amylase inhibitor selected from a compound represented by the following general formula (I): | 05/17/2011 |
| 7935673 | Polyphenol glycoside isolated from acerola It is an objective of the present invention to provide a polyphenol glycoside isolated from acerola, which has a binding mode that has not been conventionally known, and to provide the use of the same. The present invention relates to a compound represented b... | 05/03/2011 |
| 7935672 | Derivatives of genkwanin and sakuranetin, cosmetic and therapeutic use thereof and preparation method of same The invention relates to: (i) the use of osyl derivatives of genkwanin and sakuranetin having formula (I) in (a) cosmetics or dermatology and (b) therapeutics; (ii) the use of novel derivatives having formula (I) as industrial products; and (iii) the production meth... | 05/03/2011 |
| 7915228 | Derivatives of asimadoline with covalently bonded acids The present invention relates to derivatives of N-methyl-N-[(1S)-1-phenyl-2-((3S)-3-hydroxypyrrolidin-1-yl)ethyl]-2,2-diphenylacetamide with covalently bonded acids, and to the salts, solvates and prodrugs thereof, to the derivatives as medicaments, to the use of th... | 03/29/2011 |
| 7863248 | Tyrosinase activity inhibitor and ameliorant for facial blood flow A tyrosinase activity inhibitor and an ameliorant for facial blood flow that are excellent in terms of safety, and medicinal compositions, food compositions, and cosmetic preparations that contain the inhibitor and the ameliorant as active ingredients are provided. ... | 01/04/2011 |
| 7838500 | Crystalline form of 1′-(1-methylethyl)-4′-[(2-fluoro-4-methoxyphenyl)methyl]-5′-methyl-1H-pyrazol-3′-O-β-D-glucopyranoside, a method for its preparation and the use thereof for preparing medicaments The invention relates to a crystalline form of 1′-(1-methylethyl)-4′-[(2-fluoro-4-methoxyphenyl)methyl]-5′-methyl-1H-pyrazol-3′-O-β-D-glucopyranoside, to a method for the preparation thereof, as well as to the use thereof for preparing medicaments. ... | 11/23/2010 |
| 7820630 | Substituted indole-O-glucosides Substituted indole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed. ... | 10/26/2010 |
| 7816330 | Substituted benzimidazole-, benztriazole-, and benzimidazolone-O-glucosides This invention relates to substituted benzimidazole-O-glucosides, benztriazole-O-glucosides, and benzimidazolone-O-glucosides, compositions containing them, and methods of using them, for example, for the treatment or prophylaxis of diabetes and Syndrome X. ... | 10/19/2010 |
| 7816331 | Substituted indazole-O-glucosides Substituted indazole-O-glucosides, compositions containing them, and methods of using them, for example for the treatment of diabetes and Syndrome X are disclosed. ... | 10/19/2010 |
| 7811998 | Novobiocin analogues as anticancer agents Novel analogues and derivatives of novobiocin are provided, including compounds having modifications to the amide side chain, coumarin ring, and sugar moieties. The compounds of the present invention are useful as heat shock protein 90 inhibitors, and may be used as... | 10/12/2010 |
| 7799763 | Muscle-strengthening drugs and anti-inflammatory drugs A muscle-strengthening, anti-inflammatory, antiasthmatic, antidiarrheal or an antidepressant method, or a method for the treatment of diminution of vision, hepatitis, inflammatory intestinal syndrome, functional enteropathy, functional hepatopathy, functional nephro... | 09/21/2010 |
| 7772195 | Methods and compositions for the treatment of obesity, insulin related diseases and hypercholesterolemia A method for the treatment of obesity, diabetes, high cholesterol and related diseases including hyperglycemia, lipid disorders, hyperglyceridemia, dyslipidemia and atherosclerosis in mammals using anthocyanins, anthocyanidins, ursolic acid and/or betulinic acid is ... | 08/10/2010 |
| 7772194 | Pesticidal formulations The present invention relates to an active composition for controlling or eradicating Phthiraptera, Siphonaptera and Acarina Pests, typically in domestic animals, comprising a synergistic combination of at least one A83543 compound and at least one macrocyclic lacto... | 08/10/2010 |
| 7763588 | Method for increasing cognitive function and neurogenesis The invention provides a method for improving cognitive performance in a physically active subject. The invention further provides a method of enhancing neurogenesis in a physically active subject. In one embodiment, the method encompasses administering to the subje... | 07/27/2010 |
| 7737121 | Insulin secretion by anthocyanins and anthocyanidins A method for stimulating insulin secretion by anthocyanidins and anthocyanins is described. The secretion can be in vivo in mammals, including humans, or in vitro. ... | 06/15/2010 |
| 7655632 | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof The present invention provides pyrazole derivatives represented by the general formula: wherein R1 represents H, an optionally substituted C1-6 alkyl group etc.; one of Q and T represents a group repre... | 02/02/2010 |
| 7635684 | Pyrazole derivatives, medicinal composition containing the same, medicinal use thereof, and intermediate for production thereof The present invention provides pyrazole derivatives represented by the general formula: wherein R1 represents H, an optionally substituted C1-6 alkyl group etc.; one of Q and T represents a group repre... | 12/22/2009 |
| 7622451 | Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders Novobiocin analogues and pharmaceutical composition containing such compounds useful for the treatment and/or prevention of neurodegenerative disorders and autoimmune disorders. ... | 11/24/2009 |
| 7622450 | Flavone C-glycoside derivatives and compositions containing the derivatives The present invention relates to novel flavone C-glycoside derivatives or salts thereof, especially those showing an anti-allergic effect, and compositions containing them. Recently, cases of allergic diseases, especially pollenosis and atopic dermatitis have increa... | 11/24/2009 |
| 7608593 | Resin composition with biodegradable non-liquid-crystalline and liquid-crystalline polymers Processes for producing and recycling resin composition, which comprises a biodegradable polymer and a biodegradable liquid crystalline polymer, are provided. Also, a process for recycling waste paper is disclosed. ... | 10/27/2009 |
| 7608594 | Novobiocin analogues as anticancer agents Novel analogues and derivatives of novobiocin are provided, including compounds having modifications to the amide side chain, coumarin ring, and sugar moieties. The compounds of the present invention are useful as heat shock protein 90 inhibitors, and may be used as... | 10/27/2009 |
| 7576063 | Pyrazole derivative, medicinal composition containing the same, medicinal use thereof and intermediate in producing the same The present invention provides pyrazole derivatives represented by the general formula: wherein R1 represents H, an optionally substituted C1-6 alkyl group etc.; one of Q and T represents a group selec... | 08/18/2009 |
| 7576064 | Pyrazole derivative, drug composition containing the same and production intermediate therefor The present invention provides pyrazole derivatives represented by the general formula: wherein R1 represents H, an optionally substituted C1-6 alkyl, etc.; one of Q and T represents a group selected f... | 08/18/2009 |
