...that two musicians were responsible for the invention of color print film? Fascinated by photography, Leopold Godowsky and Leopold Mannes worked together to produce an easy-to-use, practical color film. They worked full time as music teachers and gave concerts while experimenting during their off hours in Mannes' kitchen. Their success earned them full-time, well-paying jobs at Kodak and their efforts resulted in Kodachrome film, which was introduced in 1935.
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| Number | Title | Issue Date |
| 7763626 | Compositions and method for enhancing the therapeutic activity of opiods in treatment of pain Compositions and methods for inhibiting opioid tolerance and opioid withdrawal-induced hyperalgesia are provided. ... | 07/27/2010 |
| 7192962 | Xanthine phosphodiesterase V inhibitor polymorphs Crystalline polymorphs of 1-ethyl-3,7-dihydro-8-[(1R,2R) -(hydroxycyclopentyl)amino]-3-(2-hydroxyethyl)-7-[(3-bromo-4-methoxyphenyl)methyl]-1H-Purine-2,6-dione in Form 1 and Form 2, which exhibit x-ray powder diffraction profiles substantially the same as those show... | 03/20/2007 |
| 7109341 | Therapeutic amides The invention provides compounds of the formula: wherein A, X, Y, and Z are as defined in the specification. The compounds are effective anti-tumor agents. The invention also provides pharmaceutical compositions ... | 09/19/2006 |
| 7034036 | Inhibitors of ABC drug transporters at the blood-brain barrier The present invention relates to inhibitors of drug transporters of the ABC protein superfamily, particularly transporters present at the blood brain barrier. ABC transporter inhibitors identified according to the invention increase brain concentrations of CNS-activ... | 04/25/2006 |
| 6995164 | Methods of treating tumors The invention provides a method of inhibiting tumor growth in a mammal, by administering to the mammal composition containing taurolidine, taurultam, or a biologically active derivative thereof. The composition is administered to directly contact a tumor cell at a d... | 02/07/2006 |
| 6624181 | Synergistic combination The invention relates to the combined administration of PDE inhibitors and 댢 adrenoceptor agonists for the treatment of respiratory tract disorders.... | 09/23/2003 |
| 6589941 | Utilization of 5' substituted nucleosides for resistance formation in cytoclastic treatment, and drug containing these nucleosides, polymers, methods of use and compositions The invention relates to a method of producing a composition and to a composition for preventing or reducing formation of resistance in cytostatic treatment comprising combining BVDU, a salt thereof or BVDU in protected form or in prodrug form with at lea... | 07/08/2003 |
| 6579895 | Use of a celecoxib composition for fast pain relief There is provided a method of rapidly relieving pain in a mammalian, preferably human, subject. The method comprises orally administering to the subject an effective pain-relieving amount of a composition comprising celecoxib formulated in such a way as t... | 06/17/2003 |
| 6503950 | Triple drug therapy for the treatment of narcotic and alcohol withdrawal symptoms A triple drug, pharmaceutical kit, composition, and method of treatment containing a combination of effective amounts of at least one anxiolytic agent, at least one centrally acting alpha antiadrenergic agent, and at least one central nervous system stimu... | 01/07/2003 |
| 6479466 | Compositions for treating viral infections, and methods therefor Methods and combinations of an agent that promotes DNA synthesis in a virally-targeted cell and a nucleoside analogue having antiviral activity are provided for treating a viral infection in a subject in need thereof. Such compositions are particularly ef... | 11/12/2002 |
| 6462051 | Composition for reducing mental fatigue, composition for maintaining and enhancing concentration, and composition for maintaining and enhancing mental vigor The present invention is intended to provide compositions which exert excellent effects allowing improvement in the mental function of humans and animals other than humans, such as reduction of mental fatigue, maintenance and enhancement of concentration ... | 10/08/2002 |
| 6440980 | Synergistic inhibition of viral replication by long-chain hydrocarbons and nucleoside analogs The present invention is related to antiviral compositions comprising long-chain aliphatic compounds in combination with a nucleoside analog or phosphonoformic acid, in a pharmaceutically acceptable carrier. Methods for treating viral infections using suc... | 08/27/2002 |
| 6432968 | Combination preparation, containing cyclosporin a or FK506 or rapamycin and a xanthine derivative Xanthines of the formula I ##STR1## are useful in producing a superadditive increase in immunosuppressive action when combined with immunosuppressive compounds such as CysA or FK506.... | 08/13/2002 |
| 6432966 | Antiviral combinations The present invention relates to therapeutic combinations comprising (2R,cis)-4-amino-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-pyrimidin-2-one (lamivudine) and BMS-200475 which have anti-hepatitis B virus (HBV) activity. The present invention is also conce... | 08/13/2002 |
| 6380267 | Composition and method for decreasing neurologic symptomatology A method of decreasing the signs or symptomatology in a patient with a neurologic condition or disease, or in a patient due to effects of exposure to an exogenous substance, such as a pharmaceutical agent, comprising selecting a patient having at least on... | 04/30/2002 |
| 6284765 | (+) naloxone and epinephrine combination therapy A composition formulated for dose-wise delivery to a breathing passageway of a human, the composition comprising a carrier solution containing (+)naloxone and a pharmacologically effective amount of at least one adrenergic agonist, the (+)naloxone and ago... | 09/04/2001 |
| 6204245 | Treatment of narcolepsy with immunosuppressants The invention provides compositions and methods for treatment of narcolepsy or isolated cataplexy. Such methods entail administering a therapeutically effective regime of at least one immunosuppressive agent. The methods are particularly useful for prophy... | 03/20/2001 |
| 6166025 | Pharmaceutical compositions containing eletriptran hemisulphate and caffeine The present invention provides an aqueous pharmaceutical composition comprising 5 to 200 mg/ml of eletriptan hemisulfate and from 0.5 to 2.0% weight/volume of caffeine.... | 12/26/2000 |
| 6159953 | Anti-malarial composition and method of use Anti-malarial compositions for prophylactic or therapeutic treatment of vertebrates exposed to malaria parasites are disclosed. These compositions comprise one or more pyrimidine analogue inhibitors of nucleic acid biosynthesis, e.g., 5-fluoro-orotic acid... | 12/12/2000 |
| 6140324 | Use of a tachykinin antagonist and a muscarinic antagonist and/or an antihistamine to treat motion sickness The present invention relates to the use of a tachykinin antagonist and a muscarinic antagonist and/or an antihistamine for the treatment or prevention of motion sickness. There is also provided pharmaceutical compositions and products comprising a tachyk... | 10/31/2000 |
| 6110955 | Metabolically stabilized oxyalkylene esters and uses thereof This invention relates to compositions for and methods of treating, preventing or ameliorating cancer and other proliferative diseases as well as methods of inducing wound healing, treating cutaneous ulcers, treating gastrointestinal disorders, treating b... | 08/29/2000 |
| 6093389 | Methods and compositions for attracting and controlling termites The present invention provides a composition for attracting termites containing a steroid derivative of formula I ##STR1## The present invention also provides a method for attracting or controlling termites with the composition.... | 07/25/2000 |
| 6037347 | Combination preparation for use in dementia The invention relates to a composition which is a pharmaceutical combination preparation comprising a compound which has an acetylcholinesterase-inhibitory action or exhibits muscarinergic action and a compound which increases the endogenous extracellular... | 03/14/2000 |
| 5990103 | Combination preparation for use in immunological diseases A combination preparation comprising a compound which has a phosphodiesterase-inhibiting action, and a compound which reduces the biologically effective intracellular Ca2+ content, is suitable for the treatment of immunological diseases.... | 11/23/1999 |
| 5981536 | Use of xanthine derivatives for the modulation of apoptosis Compounds of the formula I ##STR1## where one of the radicals R1 and R3 is a radical of the formula II --(CH2)n --A--CH3 (II) in which A is a covalent bond,--C(O)-- or --C(R4)(OH)--, a... | 11/09/1999 |
| 5916895 | Compositions and methods for controlling pest insects Compositions of a purine, a xanthine oxidase inhibitor and/or a dihydrofolate reductase inhibitor, and methods of using same, for controlling the growth of pest insects which salvage, store, or excrete their nitrogenous wastes via the purine metabolic pat... | 06/29/1999 |
| 5900416 | Aqueous caffeine dosage forms Aqueous caffeine solutions containing a co-solubilizing agent selected from niacinamide, nicotinic acid and mixtures thereof present at a level up to the maximum concentration soluble in water and in a weight ratio to caffeine less than 1.50:1, wherein th... | 05/04/1999 |
| 5874439 | Compositions and methods for controlling pest insects Compositions of a purine, a xanthine oxidase inhibitor and/or a dihydrofolate reductase inhibitor, and methods of using same, for controlling the growth of pest insects which salvage, store, or excrete their nitrogenous wastes via the purine metabolic pat... | 02/23/1999 |
| 5869479 | Treatment of upper airway allergic responses Relief from the symptoms of rhinitis is obtained by treatment with: (a) an antihistaminic effective amount of a histamine H1 receptor antagonist; together with (b) a sufficient amount of a histamine H3 receptor antagonist to provide ... | 02/09/1999 |
| 5856330 | Use of xanthine derivatives for the inhibition of dephosphorylation of cofilin Compounds of the formula I ##STR1## where one of the radicals R1 and R3 is a radical of the formula II --(CH2)n --A--CH3 (II) in which A is a covalent bond, --C(O)-- or --C(R4)(OH)--, ... | 01/05/1999 |
| 5852025 | Compositions and methods for controlling pest insects Compositions of a purine, a xanthine oxidase inhibitor and/or a dihydrofolate reductase inhibitor, and methods of using same, for controlling the growth of pest insects which salvage, store, or excrete their nitrogenous wastes via the purine metabolic pat... | 12/22/1998 |
| 5811423 | Benzoxazinones as inhibitors of HIV reverse transcriptase Certain benzoxazinones are useful in the inhibition of HIV reverse transcriptase (including its resistant varieties), the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharma... | 09/22/1998 |
| 5795897 | Oxohexyl methylxanthine compounds There is disclosed a pharmaceutical composition comprising 1-(5-oxohexyl)-3-methylxanthine in admixture with a pharmaceutically acceptable excipient, wherein the pharmaceutical composition is useful for treating an immune disorder. There is also disclosed... | 08/18/1998 |
| 5731304 | Potentiation of temozolomide in human tumour cells The toxicity of temozolomide, an anti-tumour agent useful in the treatment of various mammalian neoplasms, can be potentiated by the prior administration of an ATase inhibiting agent, i.e., O6 -benzylguanine.... | 03/24/1998 |
| 5726180 | Stabilized solid pharmaceutical preparation and method of producing the same To stabilize the active ingredients, a caffeine is incorporated into a solid pharmaceutical preparation comprising a dextromethorphan and a phenylpropanolamine. The pharmaceutical preparation may further comprise ibuprofen. The active ingredients may be f... | 03/10/1998 |
| 5691338 | 1,2-dithiole-3 thiones for the treatment of reverse transcriptase-dependent viral infections This invention provides a method of inhibiting the replication of a reverse transcriptase-dependent virus in cells which comprises contacting infected cells with an effective amount of a 1,2-dithiole-3-thione. A composition for inhibiting reverse transcri... | 11/25/1997 |
| 5668132 | HIV Protease inhibitors useful for the treatment of AIDS Compounds of formula ##STR1## where R1 and R2 are independently hydrogen or optionally-substituted C1-4 alkyl or aryl, and R1 also forms a heterocycle or heterocycle-C1-4 alkyl, are HIV protease ... | 09/16/1997 |
| 5665720 | Benzoxazinones as inhibitors of HIV reverse transcriptase Certain benzoxazinones are useful in the inhibition of HIV reverse transcriptase (including its resistant varieties), the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharma... | 09/09/1997 |
| 5663175 | Prodrugs of herpes TK inhibitors Certain prodrugs such as ##STR1## are useful in the inhibition of herpes virus thymidine kinase, the prevention or treatment of recurrent infection by herpes virus, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ... | 09/02/1997 |
| 5648358 | Compositions and methods for treating respiratory disorders The present invention relates to compositions and methods for providing improved treatment, management or mitigation of cold, cold-like, allergy, sinus and/or flu symptoms by administering a safe and effective amount of a composition comprising caffeine a... | 07/15/1997 |