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| Number | Title | Issue Date |
| 6858233 | Simmondsin processing methods and products The invention provides a process for reducing odour, bitterness, astringency and pungency of a Simmondsins extract by dissolving the Simmondsins extract in a solvent if the Simmondsins extract is in a dry form, reacting the liquid Simmondsins extract with a carbonac... | 02/22/2005 |
| 6855697 | Troxerutin with a high content of trihydroxyethylrutoside and process for its preparation The invention concerns novel troxerutin with high trihydroxy-ethyl-rutin content. Said troxerutin has at least 92 wt. % of 7,3′,4′-trihydroxyethyl rutin and a wettability expressed in minutes less than 10 minutes, when said wettability is measured in a test cons... | 02/15/2005 |
| 6852756 | Use of pleuromutilin derivatives for transdermal treatment of bacterial diseases Described is a method for transdermally controlling a bacterial infection in a non-human animal which comprises the step of topically applying to the non-human animal a medicament comprising valnemulin in free base or a pharmaceutically acceptable salt form. ... | 02/08/2005 |
| 6852707 | Remedies for hyperammonemia By using xylobiose or xylooligosaccharide containing xylobiose as a main ingredient in place of lactulose, there is provided a blood ammonia lowering agent, a therapeutic agent of hyperammonemia or a therapeutic agent of hepatic encephalopathy that need be adminster... | 02/08/2005 |
| 6849607 | Galectin recognized photosensitizers for photodynamic therapy Purpurin-carbohydrate conjugates and their method of preparation and use for treatment of cancer cells. The conjugates have the general formula: wherein R6 and R7 taken together are ═NR11 | 02/01/2005 |
| 6844329 | Polysaccharides with antithrombotic activity comprising at least a covalent bond with biotin or a biotin derivative The present invention relates to novel synthetic polysaccharides with antithrombotic activity exhibiting at least one covalent bond with biotin or a biotin derivative and to a process employing avidin or streptavidin which makes it possible to neutralize these polys... | 01/18/2005 |
| 6841536 | Prodrugs and conjugates of thiol- and selenol-containing compounds and methods of use thereof Disclosed is a prodrug of the formula: where A is a sulfur or a selenium, and R is derived from a mono- di- or oligo- saccharide. Also disclosed is a prodrug of the formula: | 01/11/2005 |
| 6838442 | Combination therapy comprising glucose reabsorption inhibitors and retinoid-X receptor modulators Combination therapy comprising RXR modulators and glucose reabsorption inhibitors useful for the treatment of diabetes and Syndrome X are disclosed. ... | 01/04/2005 |
| 6835720 | Compounds having antiviral activity In order to provide the anti-retrovirus active compound with low anti-coagulant action and low cytotoxicity, compounds comprising glycoside or the salt thereof wherein lipid is linked to position 2 of sialic acid having all hydroxyl groups at positions 4, 7, 8 and 9... | 12/28/2004 |
| 6833362 | Method and composition for the accelerated in vivo removal of ethanol A composition for accelerating the disposal of ethanol from bodily fluid. Certain additives can accelerate the metabolic oxidation of ethanol, and others in addition act as catalysts or “pseudo” enzymes for the oxidation. Additives include the oxidant Nicotinami... | 12/21/2004 |
| 6831067 | Substance having physiological property, method for producing the same and uses thereof A glucoside containing isomaltol represented by formula (I): (wherein Sug represents a glucose residue or a sugar linkage composed of two or more glucose units) as an aglycon, a physiologically active substance contain... | 12/14/2004 |
| 6828310 | Compositions including reduced malto-oligosaccharide preserving agents, and methods for preserving a material Disclosed is a composition that includes a material that is susceptible to degradation and a preserving agent in an amount effective to preserve the material comprising one or more reduced malto-oligosaccharide species. The preserving agent can include a single redu... | 12/07/2004 |
| 6828309 | Use of pentosan polysulfate to treat certain conditions of the prostate The invention relates to the field of pharmacology. More particularly, the invention relates to the treatment of prostate conditions, such as BPH. The invention provides new therapeutic compositions and methods for treating BPH, as well as chronic prostatitis, prost... | 12/07/2004 |
| 6825173 | Preparation of fagopyritols and uses therefor The present invention describes isolated Fagopyritol A1, isolated Fagopyritol A3, and isolated Fagopyritol B3. Compositions which include two or more of Fagopyritol A1, Fagopyritol A2, Fagopyritol A3, Fagopyritol B1, Fagopyritol B2, Fagopyritol B3, and D-chiro-inosi... | 11/30/2004 |
| 6822001 | Combination therapy using pentafluorobenzenesulfonamides and antineoplastic agents Combination therapies are provided for the treatment of proliferative disorders which use a pentafluorobenzenesulfonamide of formula I and an antineoplastic agent such as gemcitabine or paclitaxel. ... | 11/23/2004 |
| 6818409 | Isolation and purification of Clostridium botulinum toxins A method for separating and purifying HA-positive progenitor toxin(s) (LL and/or L toxins) and HA-negative progenitor toxin (M toxin) from a Clostridium botulinum strain is provided. The method comprises applying a liquid containing both the HA-positive proge... | 11/16/2004 |
| 6815428 | Pyrazole derivatives and diabetic medicine containing them The present invention provides pyrazole-O-glycoside derivatives represented by the following formulae, used as a diabetic medicine. ... | 11/09/2004 |
| 6812332 | Chromogenic substrates of sialidase and methods of making and using the same The subject invention discloses materials and methods for the design, synthesis, and biochemical evaluation of chromogenic substrate compounds for sialidases of bacterial, viral, protozoa, and vertebrate (including humans) origin. In particular, this invention provi... | 11/02/2004 |
| 6812245 | Polycylic xanthones and their use A novel class of antitumour compounds has been recognised based on the isolation from a new marine microbe, strain PO13-046, belonging to the genus Actinomadura sp.), of a compound designated IB-00208. The class of the formulae (I) or (II) where R1 | 11/02/2004 |
| 6812219 | Methods and compositions for treating flaviviruses and pestiviruses A method and composition for treating a host infected with flavivirus or pestivirus comprising administering an effective flavivirus or pestivirus treatment amount of a described 1′, 2′ or 3′-modified nucleoside or a pharmaceutically acceptable salt or prodrug... | 11/02/2004 |
| 6812215 | Compositions for the treatment of inflammatory joint diseases and osteoporosis Compositions and pharmaceutical compositions are described which comprise: a component A comprising one or more flavonol glycosides, a component B comprising one or more tetrahydrofolic acid compounds, a component C comprising one or more calcium supplements, and a ... | 11/02/2004 |
| 6809120 | Composition containing propargylamine for enhancing cancer therapy Antineoplastic drug modulators are described. The specific modulators referred to are propargylamines which can enhance the cytotoxic effects of antineoplastic drugs on cancer cells while protecting normal cells from damage. The propargylamine modulators can be used... | 10/26/2004 |
| 6806257 | Flavones as inducible nitric oxide synthase inhibitors, cyclooxygenase-2 inhibitors and potassium channel activators The present invention is directed to a method for inhibiting expression of either iNOS or COX-2, or both in mammals using flavone compounds, and pharmaceutically acceptable salts thereof. The present invention is also directed to a method of activating K+... | 10/19/2004 |
| 6805873 | Use of a dihydrochalcone-rich phenolic fraction in a cosmetic treatment The use of a dihydrochalcone-rich polyphenolic fraction in the cosmetic treatment of mammals in order to limit the weight, to improve the aesthetic appearance of the body, and to treat certain non-pathological forms of obesity. The use of a dietary or nutraceutical ... | 10/19/2004 |
| 6800613 | Prophylactic and therapeutic treatment of infectious and other diseases with mono- and disaccharide-based compounds Methods and compositions for treating or ameliorating diseases and other conditions, such as infectious diseases, autoimmune diseases and allergies are provided. The methods employ mono- and disaccharide-based compounds for selectively stimulating immune responses i... | 10/05/2004 |
| 6780616 | Antibiotic caprazamycins and process for producing the same There have been obtained, by cultivation of Streptomyces sp. MK730-62F2 (deposit number of FERM BP-7218), antibiotic caprazamycins A to F having by the following general formula (I) wherein R is tridecyl group, 11-methyl... | 08/24/2004 |
| 6777004 | Composition containing novel compound corniculatonin having antifungi properties and a process for preparing the same The invention relates to a novel compound oleanane triterpenoid oligoglycoside of formula 1 of the accompanying drawing (trivially called corniculatonin), the invention also relates to a process for the isolation of the novel compound from a mangrove plant Aegice... | 08/17/2004 |
| 6774113 | Process for preparing solubilization adjuvants from fusel oils and saccharides Process for preparing a solubilization adjuvant, which comprises placing fusel oils in contact with one or more reducing sugars in the presence of an acid catalyst, at a temperature of between 50° C. and 130° C. and while removing the water from the reaction mediu... | 08/10/2004 |
| 6770629 | Administration of a sulfopyranosylacylglycerol to treat certain cancers A medicament containing at least one compound selected from the group consisting of compounds represented by General formula (1): wherein R101 represents an acyl residue of an unsaturated higher fatty acid, an... | 08/03/2004 |
| 6767999 | Anthocyantin coloring agent and method for the production thereof from organic matter Anthocyanic colorant made of vegetable primary material and process for its production relate to food, cosmetic, pharmaceutical and textile industry and may be used in production of alcoholic and soft drinks, confectionery, products made of sour milk, in coloring of... | 07/27/2004 |
| 6759522 | Sulforhamnosylacyglycerol derivatives and use thereof as medicaments Novel sulforhamnosylacylglycerol derivatives represented by General Formula (1): where R101 represents an acyl residue of a higher fatty acid and R102 represents a hydrogen atom or an acyl residue o... | 07/06/2004 |
| 6759390 | Compounds and their uses Compounds having a mimetic or antagonistic property of an inositol phosphoglycan, and the uses of these compounds are disclosed, together with the use, e.g. to treat a condition ameliorated by administration of an IPG second messenger or an IPG antagonist thereof. P... | 07/06/2004 |
| 6756361 | Enterococcus antigens and vaccines A majority of E. faecalis and E. faecium clinical isolates fall into two groups and three groups, respectively. Distinct antigens are associate with each of the five groups. The Enterococcus antigens are readily obtained from strains of E. faecalis ... | 06/29/2004 |
| 6756046 | Polyol ester insecticides The present invention relates to an environmentally acceptable synthesis method of polyol esters that produces no toxic by-products methods during the synthesis and the resultant esters are environmentally friendly insecticides. The present invention also provides f... | 06/29/2004 |
| 6750209 | Advanced glycation end-product intermediaries and post-amadori inhibition The instant invention provides compositions and methods for modeling post-Amadori AGE formation and the identification and characterization of effective inhibitors of post-Amadori AGE formation, and such identified inhibitor compositions. ... | 06/15/2004 |
| 6747010 | NKT cell-activating agents containing α-glycosylceramides An objective of the present invention is to provide NKT cell-activating agents, therapeutic agents for autoimmune diseases (for example, systemic lupus erythematosus, systemic sclerosis, ulcerative colitis, encephalomyelitis, multiple sclerosis and human type I diab... | 06/08/2004 |
| 6746696 | Triterpene compositions and methods for use thereof The invention provides novel saponin mixtures and compounds which are isolated from the species Acacia victoriae and methods for their use. These compounds may contain a triterpene moiety, such as acacic or oleanolic acid, to which oligosaccharides and monote... | 06/08/2004 |
| 6743775 | Slow release formulations comprising anionic polysaccharide A slow release formulation includes a biocompatible anionic polysaccharide material containing glucuronic acid in the polymer chain. ... | 06/01/2004 |
| 6740640 | Sulfofucosylacylglycerol derivatives and administration thereof as medicaments Sulfofucosylacylglycerol derivatives represented by General Formula (1): where R101 represents an acyl residue of a higher fatty acid and R102 represents a hydrogen atom or an acyl residue of a high... | 05/25/2004 |
| 6737063 | FimH adhesin proteins and methods of use The present invention provides bacterial immunogenic agents for administration to humans and non-human animals to stimulate an immune response. Also provided are methods for vaccination of mammalian species, especially human patients, with variants of the E. coli... | 05/18/2004 |
