Class 514/246 - Polycyclo ring system having a 1,3,5-triazine as one of the cyclos

Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the six-membered heterocyclic compound
No. of patents: 111
Last issue date: 08/16/2011

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Number	Title	Issue Date
7998960	Affinity adsorbents for plasminogen For the separation, removal, isolation, purification, characterization, identification or quantification of plasminogen or a protein that is a plasminogen analogue, an affinity adsorbent is used that is a compound of formula (II) wherein one X is N and the other is ...	08/16/2011
7834014	Aadenosine receptor antagonists The invention is based on the discovery that compounds of formula (I) possess unexpectedly high affinity for the A2a adenosine receptor, and can be useful as antagonists thereof for preventing and/or treating numerous diseases, including Parkinson's disea...	11/16/2010
7750005	Substituted hexahydropyrazino [1,2-A] pyrimidine-4,7-dione derivatives, process for their preparation and their use as medicaments The invention relates to substituted hexahydropyrazino[1,2-a]pyrimidine-4,7-dione derivatives and to the physiologically tolerated salts and physiologically functional derivatives thereof. Compounds of the formula I ...	07/06/2010
7678793	Azolo triazines and pyrimidines Corticotropin releasing factor (CRF) antagonists of formula I or II: and their use in treating anxiety, depression, and other psychiatric, neurological disorders as well as treatment of immunological, cardiovascular or hear...	03/16/2010
7662817	4-(2-Butylamino)-2,7-dimethyl-8-(2-methyl-6-methoxypyrid-3-yl)pyrazolo-[1,5-A]-1,3,5-triazine, its enantiomers and pharmaceutically acceptable salts as corticotropin releasing factor receptor ligands Corticotropin releasing factor (CRF) antagonists of Formula (I): and its use in treating anxiety, depression, and other psychiatric, neurological disorders as well as treatment of immunological, cardiovascular or heart-rela...	02/16/2010
7563792	Biguanide and dihydrotriazine derivatives Biguanide and dihydrotriazine derivatives, preferably substituted asymmetrical imidodicarbonimidic diamides derived from hydroxylamines, and compositions containing biguanide and dihydrotriazine derivatives are disclosed. In addition, methods of using the biguanide ...	07/21/2009
7358252	4-(2-butylamino)-2,7-dimethyl-8-(2-methyl-6-methoxypyrid-3-yl)pyrazolo-[1,5-a]-1,3,5-triazine, its enantiomers and pharmaceutically acceptable salts as corticotropin releasing factor receptor ligands Corticotropin releasing factor (CRF) antagonists of Formula (I): and its use in treating anxiety, depression, and other psychiatric, neurological disorders as well as treatment of immunological, cardiovascular or heart-rela...	04/15/2008
7354921	Pyrazolotriazines as kinase inhibitors In its many embodiments, the present invention provides a novel class of pyrazolo[1,5-a]triazine compounds as inhibitors of kinases such as, for example, cyclin dependent kinases, methods of preparing such compounds, pharmaceutical compositions containing one or mor...	04/08/2008
7332477	Photocleavable DNA transfer agent The present invention provides visible light sensitive and ultraviolet (UV) light sensitive composition for DNA transfer comprising acid sensitive polyacetals developed as DNA/RNA delivery agents, a photoacid generator and optionally a photosensitizer. ...	02/19/2008
7220328	Low-smoke gas generating low order pressure pulse compositions Low-smoke gas generating compositions for producing a low order pressure pulse use a salt or complex of a triazolyl-tetrazinyl-triazine compound. The general chemical structure of the triazolyl-tetrazinyl-triazine is: ...	05/22/2007
7220732	Compounds useful as photodynamic therapeutic agents The present invention relates to compounds of the formula or a salt, metal complex or hydrate or other solvate thereof, wherein: M is a chelating agent; R1, R2, R	05/22/2007
7208596	Processes for the preparation of pyrazolo[1,5-a]-1,3,5-triazines and intermediates thereof The present invention provides novel processes and intermediates for preparing corticotropin releasing factor (CRF) receptor antagonists having the structure below which are useful in treating CRF-related disorders such as anxiety and depression	04/24/2007
7169805	Captopril derivatives Captopril nitroderivatives having improved pharmacological activity and enhanced tolerability are described. They can be employed for the treatment or prophylaxis of cardiovascular, inflammatory and renal diseases. ...	01/30/2007
7157578	4-(2-butylamino)-2, 7-dimethyl-8-(2-methyl-6-methoxypyrid-3-YL) pyrazolo-[1,5-A]-1,3,5-triazine, its enantiomers and pharmaceutically acceptable salts as corticotropin releasing factor receptor ligands Corticotropin releasing factor (CRF) antagonists of Formula (I): and its use in treating anxiety, depression, and other psychiatric, neurological disorders as well as treatment of immunological, cardiovascular or...	01/02/2007
7153961	Salt and crystalline form thereof of a corticotropin releasing factor receptor antagonist The present invention provides 4-(bis(2-methoxyethyl)amino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-[1,5-a]-pyrazolo-1,3,5-triazine benzenesulfonate salt and a crystalline polymorph thereof. Further provided are pharmaceutical compositions containing the salt and ...	12/26/2006
7129239	Purine compounds and uses thereof Compounds of Formula (I) that act as cannabinoid receptor ligands and their uses in the treatment of diseases linked to the mediation of the cannabinoid receptors in animals are described herein. ...	10/31/2006
7097860	Method and composition for treatment of inflammatory and inflammation-related disorders A method of reducing inflammation in a variety of disorders by using an intraperitoneal solution of magnesium. The solution can be used for treating inflammatory and inflammation-related disorders in animals and/or humans. Application of the solution reduces inflamm...	08/29/2006
7094782	Azolo triazines and pyrimidines Corticotropin releasing factor (CRF) antagonists of formula I or II: and their use in treating anxiety, depression, and other psychiatric, neurological disorders as well as treatment of immunological, cardiovascu...	08/22/2006
7091203	Imidazo[1,3,5]triazinones and their use The invention relates to imidazo[1,3,5]triazinones, a method for their production and methods of use, in particular as inhibitors of cyclic GMP metabolizing phosphodiesterases. ...	08/15/2006
7074797	Pyrazolopyrimidines as CRF receptor antagonists This invention concerns compounds of formula including the stereoisomers and the pharmaceutically acceptable acid addition salt forms thereof, wherein R1 is NR4R5 or OR5	07/11/2006
7034154	Synthesis of substituted pyrazolopyrimidines Methods of making substituted pyrazolopyrimidines generally and, more particularly, N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide. Such compounds have utility over a wide range of indications, including treatment of insomnia. ...	04/25/2006
7026317	Pyrazolotriazines as CRF antagonists The present invention relates to pyrazolotriazines according to formula (I) and stereoisomers, isomers and salts thereof wherein R1-R5 are selected from certain alkyl, aryl and heteroaryl species ...	04/11/2006
7015222	Agricultural compositions An agricultural composition comprising the chemical formula, or salt thereof, of: wherein Rx is —NH2, —OH, halogen, akylamino, SR1, carboxyalkyl, carboxy, or a sulfonam...	03/21/2006
6960583	Pyrazolotriazines as CRF antagonists The present invention relates to pyrazolotriazines according to formula (I) and stereoisomers, isomers and salts thereof wherein R1-R5 are selected from certain alkyl, aryl and heteroaryl species ...	11/01/2005
6958341	Pyrazolopyrimidines as CRF antagonists The present invention relates to pyrazolopyrimidines according to formula (I) and stereoisomers, isomers and salts thereof wherein R1-R5 are selected from certain alkyl, aryl and heteroaryl specie...	10/25/2005
6919453	Colorant compositions Colorant compositions, and intermediate chemical compositions of colorant compositions are made from 1,2,4-triazolo[4,3-a][1,3,5]triazine-3,5,7-substituted compounds. ...	07/19/2005
6903097	Heterocycle carboxamides as antiviral agents The present invention provides a compound of formula I which is useful as antiviral agents, in particular, as agents against viruses of the herpes family. ...	06/07/2005
6806268	Method for treating glaucoma V Provided, among things, is a method of decreasing intraocular pressure in an animal, including a human, comprising administering an intraocular pressure decreasing amount of a compound of the formula IA and or IB: ...	10/19/2004
6803365	Imidazo[1,3,5]triazinones and the use thereof The invention relates to imidazo[1.3.5]triazinones, a method for their production and methods of use, in particular as inhibitors of cyclic GMP metabolizing phosphodiesterases. ...	10/12/2004
6800640	Azaindolylalkylamine derivatives as 5-hydroxytryptamine-6 ligands The present invention provides a compound of formula I and the use thereof for the therapeutic treatment of disorders relating to or affected by the 5-HT6 receptor. ...	10/05/2004
6740654	Squaric acid derivatives Squaric acid derivatives of formula (1) are described: wherein Het is an optionally substituted bicyclic fused ring heteroaromatic group; L2 is a covalent bond or an atom or group —O—, —S�...	05/25/2004
6683080	Treatment of diabetes mellitus Use of vardenafil or a pharmaceutical composition thereof in the preparation of a medicament for the curative, palliative or prophylactic treatment of type 2 diabetes mellitus....	01/27/2004
6660737	Medicinal uses of hydrazones Compounds having a structure according to Formula (I): ##STR1## are effective in a method of increasing erythropoietin and vascularization of tissue in a subject in need thereof....	12/09/2003
6630470	G-CSF mimetics Invented are G-CSF mimetics. Also invented are selected octacyclic compounds, pharmaceutical compositions containing these compounds, and methods of using these compounds as G-CSF mimetics. Also invented are novel processes used in preparing these compoun...	10/07/2003
6566365	Method for the treatment of Flaviviridea viral infection using nucleoside analogues In accordance with the present invention there is provided a method for treating or preventing a Flaviviridea viral infection in a host comprising administering a therapeutically effective amount of at least one compound of formula (I) or (II) ##STR1...	05/20/2003
6559147	Polyhydroxylated monocyclic N-heterocyclic derivatives as anti-coagulants This invention is directed to poly-hydroxylated monocyclic N-heterocyclic derivatives selected from the following formulae: ##STR1## wherein Z1, Z2, R1, R2, R3, R4, R5, R6	05/06/2003
6509338	Pyrazolo[1,5-A]triazine corticotropin releasing factor antagonists The present invention describes novel pyrazolo[1,5-a]triazines of formula: ##STR1## wherein R3 is an alkyl, alkenyl, alkynyl, or cycloalkyl group, or pharmaceutically acceptable salt forms thereof, which are useful as CRF antagonists....	01/21/2003
6489333	Integrin antagonists This invention relates to novel heterocycles which are useful as antagonists of the ଱vଲ.sub.3 integrin, the 򳄫ଲ.sub.3 integrin, and related cell surface adhesive protein receptors, to pharmaceutical compositi...	12/03/2002
6482815	Organic-arsenic compounds Novel organic arsenic compounds are described as cytotoxic agents with potent anti-tumor activity against cancer cells and particularly, with regard to human leukemic cells and breast cancer cells....	11/19/2002
6476028	Compounds and methods A method of treating a CCR5-mediated disease state in mammals which comprises administering to a mammal in need of such treatment, an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof. ##STR1##...	11/05/2002

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Class 514/246 - Polycyclo ring system having a 1,3,5-triazine as one of the cyclos