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Class 514/227.5 - 1,4-Thiazines


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter in which the hetero ring has the following
No. of patents: 418
Last issue date: 05/08/2012


                9      
NumberTitleIssue Date
4588719Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use
A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity, including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of...
05/13/1986
4585796Novel phenethanolamines
The tertiary amines of the formula ##STR1## wherein n represents a whole number of 1 to 5; X1 represents phenyl or phenyl mono-, di- or tri-substituted by R1, R2 and R3 ; X2 represents hydrogen, lower...
04/29/1986
4562211Pharmaceutically active 2-substituted-1-(omega-aminoalkoxy)benzenes
2-Substituted-1-(omega-aminoalkoxy)benzenes are prepared and found useful as pharmaceutical agents, particularly as antidepressants....
12/31/1985
4552875Novel carbacyclinamides, their preparation and use as medicinal agents
Carbacyclinamides of Formula I ##STR1## wherein R1 is NHR4, wherein R4 is H, --(CH2)n --R8 or straight-chained or branched aliphatic groups of 1-10 carbon atoms, cycloalkyl of 3-10 car...
11/12/1985
4551472Unsymmetrical bis-carbamate compounds
Unsymmetrical N-substituted bis-carbamoyl sulfide compounds exhibit exceptional broad spectrum pesticidal activity coupled with extremely low mammalian toxicity and phytotoxicity....
11/05/1985
4544654Substituted sulfonamidobenzamides, antiarrhythmic agents and compositions thereof
Novel substituted sulfonamidobenzamides are described as useful antiarrhythmic agents. Their use in the treatment of cardiac arrhythmias, especially re-entrant arrhythmias, via the prolongation of the action potential of cardiac tissue is provided. Pharma...
10/01/1985
4539320Humectant compositions containing thiamorpholinone or a derivative thereof
A composition for topical application to the skin comprises, in an appropriate cosmetic vehicle, as an active agent, a compound of the formula ##STR1## wherein, R1 and R2 represent hydrogen or lower alkyl; R3 rep...
09/03/1985
4539319Amidine derivatives
Compounds of formula (I) ##STR1## and acid addition salts thereof, wherein R1 is hydrogen, hydroxy, alkoxy, aryloxy, aralkoxy, heteroaryloxy or heteroaralkoxy; and one of R2, R3 and R4 is hydrogen and the others...
09/03/1985
4530925Aminocyclopentane esters and pharmaceutical formulations
Compounds are described of the formulae (1a) and (1b) ##STR1## in which: --COR1 is an ester group, n is 1 or 2, W is C1-7 alkylene, X is cis or trans --CH.dbd.CH or --CH2 CH2 --, Y is a saturated heterocyclic amino g...
07/23/1985
4529723Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use
A class of bicyclic benzenoid aminoalkylene ether and thioether compounds exhibiting pharmacological activity including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of ...
07/16/1985
451439615-Cycloaliphatic derivatives of 13,14-didehydro-carboprostacyclins and process for their preparation
13, 14 didehydro-15 cyclic prostacyclins have been prepared....
04/30/1985
4507292Combating pests with aryl N-oxalyl-N-methyl-carbamates
Aryl N-oxalyl-N-methyl-carbamates of the general formula ##STR1## in which X represents an alkoxy, alkenoxy, alkinoxy, aryloxy, alkylthio, alkenylthio, alkinylthio or arylthio radical, each of which may be optionally substituted, or represents a radi...
03/26/1985
4503051Substituted 3-cyclobutene-1,2-diones, pharmaceutical compositions thereof and methods of use
Compounds of the formula ##STR1## wherein R12 is a leaving group, Z is S, O or CH2 and A is a phenyl, furyl, thienyl or pyridyl ring substituted by a ##STR2## moiety, in which R8 and R9 are various sub...
03/05/1985
4491586Amine derivatives
The invention provides compounds of the general formula (I) ##STR1## and physiologically acceptable salts, hydrates and bioprecursors thereof in which the substituents are defined in the specification. The compounds of formula (I) show pharmacologically a...
01/01/1985
4486439Treatment of coccidiosis
A method for the preventive and curative treatment of coccidial infections in humans and other animals comprising the administration thereto of an amidinourea of amidinothiourea....
12/04/1984
4482549Aminocyclopentane esters and pharmaceutical formulation
Compounds are described of the formula ##STR1## in which --COR1 is a complex ester or thioester group, W is alkylene, X is cis or trans --CH.dbd.CH or --CH2 CH2 --, n is 1 or 2, Y is a saturated heterocyclic amino group having ...
11/13/1984
4472412Control of fungi using phenylpropylammonium salts
A fungicidal agent contains a phenylpropylammonium salt of the formula ##STR1## where R1, R2 and R3 are each hydrogen, unsubstituted or substituted alkyl, unsubstituted or substituted aryl or aralkyl, cycloalkyl, alko...
09/18/1984
4466965Phthalazine compounds, compositions and use
The present invention relates to new compounds of the formula ##STR1## alkylene, or --S-- where R1 is hydrogen, alkyl, or aryl; W is hydrogen, hydroxy, amino, alkyloxy, aryloxy, O-alkyl, or O-aralkyl; (Y)A is --CH2 NR...
08/21/1984
4464370Cyclohexene containing morpholines and fungicidal use
Cyclohexene derivatives of the formula I ##STR1## where R1 and R2 are hydrogen or tert.-butyl and N and X are members of a heterocyclic ring in which X is an alkylene chain of four, five or six members, one of which may be a het...
08/07/1984
4454134Amide carbamates and amide oxime compounds
Amide oxime compounds are useful intermediates in the preparation of pesticidally active amide carbamate compounds....
06/12/1984
4447428Prostanoid compounds and pharmaceutical compositions
Prostanoid compounds are described having the formula: ##STR1## where A is a cyclopentane ring, which is substituted by oxo and/or hydroxy or etherified hydroxy and may be saturated or unsaturated; X is --CH.dbd.CH--or --(CH2)2 ...
05/08/1984
4440765Amidinoureas
A novel method of treating gastrointestinal, spasmolytic and ulcerogenic disorders by the administration of amidinoureas is disclosed....
04/03/1984
4438112Prostanoid compounds and pharmaceutical formulations
Prostanoids are described of the formulae ##STR1## (and the salts thereof) in which: X is cis or trans --CH.dbd.CH-- or CH2 CH2 --; R1 is C1-7 alkyl terminated by --COOR10 where R10 is H, ...
03/20/1984
4432994Pesticide compounds, compositions and methods
Novel compounds are described which are substituted benzophenone hydrazones. They have pesticidal activity, especially against insects and acarids, and pesticidal compositions and methods are described. Methods of making the compounds, and novel intermedi...
02/21/1984
4427676Thiomorpholine derivatives
The invention provides novel thiomorpholines of the formula (I) ##STR1## and their pharmaceutically acceptable acid addition salts wherein n represents 0 or 1, R1 represents (lower)alkyl, R2 represents hydrogen or (lower)alkyl, ...
01/24/1984
4427687Thiazoline carbamoyl-oximes
Carbamoyl-oxime compound of the formula ##STR1## wherein A, R3, R4 and R5 are as hereinafter set forth, a process for their preparation, pesticidal compositions containing one or more of these compounds as the active ...
01/24/1984
4414220Organic diamine therapeutic compositions
A series of organic diamine base compounds derived from either an aromatic, alicyclic or heterocyclic ring and possessing, for the most part, an intervening methylene group between the ring and the aforesaid basic moiety have been prepared, including thei...
11/08/1983
4414211Heterocyclic derivatives of guanidine
5-Membered, 6-membered and 7-membered heterocyclic derivatives of guanidine having hypoglycemic activity....
11/08/1983
4411899Substituted derivatives of amino alkane diols as gastric secretion inhibitors
There are disclosed substituted derivatives of amino alkane diols and related compounds as well as processes for the preparation of such compounds. These compounds are useful for the suppression of gastric acid secretions in mammals and compositions for s...
10/25/1983
4410521Aminocyclopentane esters and pharmaceutical formulations
Compounds are described of the formula ##STR1## in which --COR1 is a complex ester or thioester group, W is alkylene, X is cis or trans --CH.dbd.CH or --CH2 CH2 --, n is 1 or 2, Y is a saturated heterocyclic amino group having ...
10/18/1983
4409213Prostanoid compounds and pharmaceutical compositions
Prostanoid compounds are described having the formula: ##STR1## where A is a cyclopentane ring, which is substituted by oxo and/or hydroxy or etherified hydroxy and may be saturated or unsaturated; X is --CH.dbd.CH-- or --(CH2)2...
10/11/1983
4394387Compositions and method of combatting pest employing substituted benzophenone hydrozones or semicarbazones
Novel compounds are described which are substituted benzophenone hydrazones. They have pesticidal activity, especially against insects and acarids, and pesticidal compositions and methods are described. Methods of making the compounds, and novel intermedi...
07/19/1983
4378357Novel heterocyclic compounds
This invention relates to novel heterocyclic fungicides which are effective in controlling a broad spectrum of phytopathogenic fungi found in the four main classes of fungi namely Phycomycetes, Ascomycetes, Fungi Imperfecti, and Basidiomycetes. Certain of...
03/29/1983
4372775Inhibition of microbiological growth with thiazine quaternary ammonium salts of polyepihalohydrin
This invention relates to thiazine quaternary ammonium salts of polyepihalohydrin and the preparation and uses thereof. The compositions are ideally expressed by the polymer unit ##STR1## where Z is S, SO, or SO2, R is hydrogen or a hydroc...
02/08/1983
4371530Aminocyclopentanone amides and pharmaceutical formulation
Compounds are described of the formula ##STR1## in which R1 is unsubstituted or substituted phenylalkyl, thienylalkyl or naphthylalkyl, or cinnamyl; R2 is a hydrogen atom, methyl or alkyl substituted by alkoxy or --COOH; W is al...
02/01/1983
4369189Novel unsymmetrical formamidine-sulfenylated carbamate compounds
Novel unsymmetrical formamidine-sulfenylated carbamate compounds exhibit broad-spectrum insecticidal, miticidal and nematocidal activity....
01/18/1983
4342762Basic ethers and pharmaceutical compositions containing the same
The invention relates to novel basic ethers of the general formula /I/ and pharmaceutically acceptable acid addition salts and quaternary salts thereof, ##STR1## wherein R1 and R2 may be the same or different and represent a ...
08/03/1982
4342759Antithrombotic method
A method of treating a patient susceptible to thrombosis is provided which comprises treating the said patient with a compound of the formula ##STR1## wherein R' is H or CH3 R is a ##STR2## radical in which Z is 0, S, SO, SO2
08/03/1982
4342756Aminocyclopentane alkenoic acids and esters and pharmaceutical compositions
Compounds are described of the formula ##STR1## (and their salts and solvates) in which: X is cis or trans --CH.dbd.CH--; R1 is C1-7 alkyl terminated by --COOR3 where R3 is H, C1-6 alkyl or C7-10...
08/03/1982
4341795Asymmetrical bis-carbamate compounds
Asymmetrical N-substituted bis-carbamoyl sulfide compounds exhibit exceptional broad spectrum pesticidal activity coupled with extremely low mammalian toxicity and phytotoxicity....
07/27/1982
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