Bizarre Patents
Neuroimaging as a Marketing Tool
Neuroimaging as a means for validating whether a stimulus such as advertisement, communication, or product evokes a certain mental response such as emotion, preference, or memory, or to predict the consequences of the stimulus on later behavior such as consumption or purchasing.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7687490 | 2-thioethenyl substituted carbapenem derivatives An objective of the present invention is to provide compounds that are effective against various resistant bacteria which cause current clinical problems, for example, pneumococci including penicillin resistant Streptococcus pneumoneae (PRSP), Haemophilus ... | 03/30/2010 |
| 7439253 | Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors The invention relates to novel heterocyclic compounds of general formula (I), and their salts with a base or an acid: The invention also relates to a method for preparing these compounds, and to their use as medicaments, in p... | 10/21/2008 |
| 7354929 | Cannabinoid receptor ligands and uses thereof Compounds of Formula (I) that act as cannabinoid receptor ligands and their uses in the treatment of diseases linked to the mediation of the cannabinoid receptors in animals are described herein ... | 04/08/2008 |
| 7335681 | Amino ceramide-like compounds and therapeutic methods of use Novel prodrugs of amino ceramide-like compounds are provided which inhibit glucosyl ceramide (GlcCer) formation by inhibiting the enzyme GlcCer synthase, thereby lowering the level of glycosphingolipids. The compounds of the present invention have improved GlcCer sy... | 02/26/2008 |
| 7220737 | Noribogaine in the treatment of pain and drug addiction The present invention is directed to methods of treating patients for pain by administering noribogaine. Noribogaine may also be used to treat patients for the symptoms associated with withdrawal from drug dependency. In the latter case, the noribogaine treatment sh... | 05/22/2007 |
| 7202236 | Modified release pharmaceutical formulation A modified release pharmaceutical composition comprising, as active ingredient, a compound of formula (I), wherein R1 represents C?1-2#191 alkyl substituted by one or more fluoro substituents; R2 represents hydrogen, hydroxy, methoxy or ethoxy;... | 04/10/2007 |
| 7148251 | Amino ceramide-like compounds and therapeutic methods of use Novel prodrugs of amino ceramide-like compounds are provided which inhibit glucosyl ceramide (GlcCer) formation by inhibiting the enzyme GlcCer synthase, thereby lowering the level of glycosphingolipids. The compounds of the present invention have improved GlcCer sy... | 12/12/2006 |
| 7138414 | Heterocyclically substituted benzoylureas, process for their preparation and their use as pharmaceuticals The invention relates to heterocyclically substituted benzoylureas and also to their physiologically tolerated salts and physiologically functional derivatives. Compounds are described of the formula I whe... | 11/21/2006 |
| 6967196 | Sulfonamide compounds and uses thereof In accordance with the present invention, there is provided a novel class of sulfonamide compounds. Compounds of the invention contain a core sulfonamide group. Variable moieties connected to the sulfur atom and nitrogen atom of the sulfonamide group include substit... | 11/22/2005 |
| 6919367 | Substituted thioacetamides The present invention is directed to chemical compositions of substituted thioacetamides, processes for the preparation thereof and uses of the compositions in the treatment of diseases. ... | 07/19/2005 |
| 6831078 | Azetidinecarboxamide derivatives for treating CNS disorders A compound of formula (1) wherein R1 is aryl; and R2 is hydrogen or alkyl; pharmaceutically acceptable addition compounds thereof; and their use in therapy, particularly for the treatment and prophylaxis of CNS disorders such as anxiety and epi... | 12/14/2004 |
| 6514962 | Stabilized preparations of ଲ-lactam antibiotic Stabilized preparations which contain a ଲ-lactam antibiotic having an esterified carboxyl group attached directly to the mother nucleus, an oil and a phosphate.... | 02/04/2003 |
| 6482818 | C-2 S/O-and S/N formaldehyde acetal derivatives of carbapenem-3-carboxylic acids and their use as antibiotics and ଲ-lactamase inhibitors The compounds of the general formula I ##STR1## wherein R1 denotes hydrogen, hydroxymethyl or 1-hydroxyethyl, R2 denotes hydrogen or methyl and R3 denotes a pharmaceutically acceptable group which is bonded to the remainin... | 11/19/2002 |
| 6426342 | Use of ଲ-lactamase inhibitors as neuroprotectants Novel neuroprotectant methods are described. ଲ-Lactamase inhibitors are used to prevent or reduce loss of neuronal cells and neuronal cell function in patients afflicted with or susceptible to disease states or conditions known to result in or cause... | 07/30/2002 |
| 6251891 | Carbapenem derivatives A compound represented by the general formula ##STR1## wherein R1 either represents a hydrogen atom or a lower alkyl group, R2 represents a hydrogen atom, an ester residue, an alkali metal or negative charge, and R3 and R | 06/26/2001 |
| 6225305 | Substituted urea and isothiorea derivatives as no synthase inhibitors The use of an N-substituted urea derivative for the manufacture of a medicament for the treatment of a condition where there is an advantage in inhibiting the NO synthase enzyme, in particular cerebral ischemia, and pharmaceutical formulations therefor ar... | 05/01/2001 |
| 6204260 | Non-peptidyl vasopressin V1a antagonists This invention provides methods and 2-(azetidin-2-on-1-yl)acetic acid derivatives for the antagonism of the vasopressin V1a receptor.... | 03/20/2001 |
| 5273973 | Antimicrobial quinolonyl esters Antimicrobial quinolnyl lactam esters comprising a lactam-containing moiety linked, by an ester group, to the 3-carboxy group of a quinolone moiety. These compounds are of the formula: ##STR1## wherein (1) R3, R4, and R5 | 12/28/1993 |
| 5242914 | 2-(heterocyclylthio) carbapenem derivatives, their preparation and their use as antibiotics Compounds of formula (I): ##STR1## in which Ra is a group of formula (II): ##STR2## where one of R' is a bond to the remainder of the compound, one more of R' is R2 and the others of R' are all hydrogen, R1 is hy... | 09/07/1993 |
| 5116833 | Antibiotic C-3 dithioacetal-substituted carbapenem compounds, compositions, and methods of use thereof A dithioacetal carbapenem of the formula ##STR1## in which R1 is hydrogen or C1-6 alkyl; n is 0, 1 or 2; R3 is hydrogen or C1-6 alkyl; R2 is C1-6 alkyl, phenyl optionally substituted with cyano,... | 05/26/1992 |
| 5104867 | 2-(heterocyclylthio)carbapenem derivatives, their preparation and their use as antibiotics Compounds of formula (I): ##STR1## in which Ra is a group of formula (II): ##STR2## or a group of formula (III): ##STR3## (where one of R' is a bond to the remainder of the compound, one more of R' is R2 and the o... | 04/14/1992 |
| 4863916 | Substituted 6-hydroxymethyl-carbapenem antibiotics Substituted 6-hydroxymethyl-carbapenem antibiotics of the formula ##STR1## in which R1 is --OR4, ##STR2## A is a direct bond, or an alkylene and/or cycloalkylene radical, R2 is a group of the formula ##STR3#... | 09/05/1989 |
| 4771046 | Carbapenem derivatives Carbapenem derivatives useful as antibacterial agents have the formula ##STR1## wherein: X represents a hydrogen atom or a methyl group; and Y represents a group of the formula: ##STR2## in which: Z represents an oxygen atom or two hydrogen atoms; R | 09/13/1988 |
| 4720490 | Fluoralkylatedcarbapenem derivatives 6-(1'-fluorethyl)- and 6-(1'-fluoro-1'-methylethyl)-carbapenems such as (5RS,6RS)-1-aza-6-(1(RS)-fluorethyl)-3-(N'-dimethyl-N'-methylamidinomethyl thio)-7-oxobicyclo[3.2.0]hept-2-ene-2-carboxylic acid which are useful as chemotherapeutic agents in particul... | 01/19/1988 |
| 4720491 | Fluoralkylatedcarbapenem derivatives Compounds of formula I ##STR1## wherein, R1 represents hydrogen or methyl, R2 represents hydrogen or lower alkyl, lower alkenyl, lower alkynyl or cycloalkyl each of which may be unsubstituted or mono- or poly-substituted by amin... | 01/19/1988 |
| 4698339 | Carbapenems, their production and use A compound of the general formula: ##STR1## wherein X is a lower alkylene group which may optionally be substituted by a hydroxyl group, or a lower alkenylene group, Y is (1) a lower alkyl group, (2) a cycloalkyl group containing 3 to 8 carbon atoms,... | 10/06/1987 |
| 4683226 | 6-hydroxyalkyl-2-(substituted-thio)penem-3-carboxylic acids 6-substituted-hydrocarbon-2-(substituted-thio)penem-3-carboxylic acids and cogeners having useful antibacterial activity are disclosed. The compounds are prepared in a reaction sequence starting with a 4-acyloxy-2-azetidinone.... | 07/28/1987 |
| 4495197 | N-Carboxyl-thienamycin esters and analogs thereof as anti-inflammatory agents Derivatives of N-carboxyl-thienamycin esters and analogs thereof are found to be potent elastase inhibitors and thereby useful anti-inflammatory agents.... | 01/22/1985 |
| 4493839 | 1-Carbapenem-3-carboxylic esters as anti-inflammatory agents Derivatives of 1-carbapenem-3-carboxylic esters are found to be potent elastase inhibitors and therefore are useful anti-inflammatory agents.... | 01/15/1985 |
| 4473578 | ଲ-Lactam antibiotics and their use The compounds of the formula: ##STR1## and pharmaceutically acceptable salts and in-vivo hydrolysable esters thereof wherein R1 is a hydrogen atom or a group selected from OH, OSO3 H or a pharmaceutically acceptable salt or C | 09/25/1984 |
| 4446146 | ଲ-Lactam containing compounds, their preparation and use The compounds of the formula (II): ##STR1## wherein R1 is a group such that CO2 R1 is a carboxylic acid group or a salt or ester thereof; R2 is a group of the sub-formula (a) or (b): wherein R4 i... | 05/01/1984 |
| 4444783 | ଲ-Lactam antibacterial agents, a process for the preparation and use in pharmaceutical compositions The compounds of the formulaes (IV), (V) and (VI): ##STR1## and salts and esters thereof where X is a bromine or chlorine atom, and n is 0 or 1; are antibacterial agents. Their preparation and use is described.... | 04/24/1984 |
| 4428961 | ଲ-Lactam containing compounds, their preparation and use The present invention provides a compound of formula (I): ##STR1## wherein R1 is a group such that COOR1 is a carboxyic acid group or a salt or ester thereof; R3 is hydrogen or an organic radical; n is zero or 1; R4 | 01/31/1984 |
| 4426390 | Novel ଲ-lactam compounds, process for producing thereof, and use thereof as medicines A compound of the formula ##STR1## wherein R1 represents a hydrogen atom, --OH or --OSO3 H, and R2 represents a hydrogen atom or an unsubstituted or substituted benzyl group; and a salt thereof; processes for producti... | 01/17/1984 |
| 4413000 | ଲ-Lactam antibiotics, their preparation and use The present invention provides the compounds of the formula (II): ##STR1## and salts and esters thereof wherein R3 is a hydrogen atom or is an organic bonded via a carbon atom to the carbapenem ring, n is zero or one, X is a saturated or u... | 11/01/1983 |
| 4404218 | Antibiotic SF-2103A substance and process for production thereof An antibiotic SF-2103A substance or a salt thereof, and a process for the production thereof are described, and the process comprises cultivating an antibiotic SF-2103A substance-producing strain in a nutrient medium and recovering the desired substance f... | 09/13/1983 |
| 4397861 | N- And carboxyl derivatives of thienamycin Disclosed are N-acyl and carboxyl derivatives of the antibiotic thienamycin, which has the following structure: ##STR1## Such derivatives are useful as antibiotics. Also disclosed are processes for the preparation of such derivatives, pharmaceutical ... | 08/09/1983 |
| 4382949 | 2-(Amino acid-thio)-1-carbapen-2-em-3-carboxylic acids and congeners 2-(Amino acid-thio)-1-carbapen-2-em-3-carboxylic acids and congeners having useful antibacterial activity are disclosed. The compounds are prepared in a reaction sequence starting with a 4-allylazetidinone.... | 05/10/1983 |
| 4376774 | Antibiotic N-heterocyclyl thienamycin This invention relates to a new class of thienamycins (I) and their pharmaceutically acceptable salts and esters which are useful as antibiotics: ##STR1## wherein the stylized radical (hereafter referred to as R'): ##STR2## attached to the ... | 03/15/1983 |
| 4374144 | ଲ-Lactam compounds, their preparation and use The present invention relates to the preparation of compounds of the formula: ##STR1## wherein CO2 R1 is a free, salted or esterified carboxyl group, n is 0 or 1, and R2 is hydrogen or an acyl group or a group of the ... | 02/15/1983 |
