Bizarre Patents
User-operated amusement apparatus for kicking the user's buttocks
An apparatus including a user-operated and controlled apparatus for self-infliction of repetitive blows to the user's buttocks by a plurality of elongated arms bearing flexible extensions that rotate under the user's control.
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| Number | Title | Issue Date |
| 7700581 | Cephalosporin compounds comprising a C3 thio-methyl moiety substituted with N-containing heterocyclic group, and a C7 thiourea acetamido group, their preparations and uses thereof Disclosed herein are a cephalosporin compound of formula I, wherein R1 is selected from the following groups: | 04/20/2010 |
| 7282221 | Antiviral product, use and formulation thereof An antiviral product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antiviral product being reached in less than about twelve hours. In one embodiment, there is an immediate release dosag... | 10/16/2007 |
| 7128897 | Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis Pharmaceutical compositions are described that contain one agent for treatment of sinusitis and a surfactant. The compositions are prepared to have a surface tension that renders the composition effective for treatment of sinusitis. ... | 10/31/2006 |
| 7071329 | Process for preparing cephalosporins with salified intermediate Cephalosporins may be conveniently prepared by a process in which a benzathinium salt of formula (V) wherein: Z is benzathine; and X and R2 are as defined in the spec... | 07/04/2006 |
| 6916801 | 7-Alkylidene-3-substituted-3-cephem-4-carboxylates as β-lactamase inhibitors The invention provides compounds of formula (I): wherein: R1-R4 and A have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for inhibiting β... | 07/12/2005 |
| 6906054 | Compositions for inhibiting beta-lactamase The invention provides pharmaceutical compositions comprising compounds of formula I and IV: wherein R1-R11 and A have any of the values defined in the specification, and ... | 06/14/2005 |
| 6846492 | Use of phenylethylamine derivatives for the antimicrobial treatment of surfaces The use of compounds of formula (1) is described, in which compounds R1, R2 and R3 are each independently of the others hydrogen; C1-C20alkyl; C3-C7cycloalkyl; C2-C20a... | 01/25/2005 |
| 6723716 | 7-acylamino-3-heteroarylthio-3-cephem carboxylic acid antibiotics and prodrugs thereof The present invention relates to a cephem prodrug having formula III or formula IV: or a pharmaceutically acceptable salt thereof, wherein R′1 is selected from the group consisting of hydrogen and —C(O)CH(... | 04/20/2004 |
| 6599893 | Cephalosporin antibiotics and prodrugs thereof The present invention relates to chemical compounds having the formula: ##STR1## or a pharmaceutically acceptable salt thereof. R1 is selected from the group consisting of: ##STR2## R2 is selected from the group consisting of hydroge... | 07/29/2003 |
| 6599892 | 7-alkylidene cephalosporanic acid derivatives and methods of using the same Derivatives of 7-alkylidene cephalosporanic acid sulfone and the pharmaceutically active salts thereof are found to be potent inhibitors of ଲ-lactamase enzymes.... | 07/29/2003 |
| 6583133 | Propenyl cephalosporin derivatives and process for the manufacture thereof Disclosed are cephalosporin derivatives of the general formula ##STR1## wherein R is an organic residue with a molecular weight not exceeding 400 bonded to the adjacent sulphur atom via carbon and consisting of carbon, hydrogen, and optional oxygen, sulfu... | 06/24/2003 |
| 6531465 | Antibacterial cephalosporins A compound of formula ##STR1## wherein Ac, R1 and R2 have various meanings, a process for a preparation thereof and its use as a pharmaceutical, i.e. as antibacterial agent.... | 03/11/2003 |
| 6414002 | Substituted acid derivatives useful as antidiabetic and antiobesity agents and method Compounds are provided which have the structure ##STR1## wherein Q is C or N, A is 0 or S, Z is O or a bond, X is CH or N and R1, R2, R2a, R2b, R2c, R3, Y, x, m, and n are as defined herein... | 07/02/2002 |
| 6407091 | ଲ-lactamase inhibiting compounds The invention provides compounds of formula I and IV: ##STR1## wherein R1 -R11 and A have any of the values defined in the specification, and their pharmaceutically acceptable salts, are useful for inhibiting ଲ-lactamase enzyme... | 06/18/2002 |
| 6329363 | Cephalosporin antibiotics The invention provides new fluorinated cephalosporin antibiotics and methods of preventing or treating infection, particularly mastitis in ruminants, using these antibiotics, and veterinary and pharmaceutical formulations comprising these antibiotics.... | 12/11/2001 |
| 6319904 | Formulation comprising antibacterial substance and antiulcer substance The present invention includes a formulation which comprises an antibacterial substance and an antiulcer substance, wherein at least either of them is formulated into a gastrointestinal mucosa-adherent solid preparation. The formulation of the present inv... | 11/20/2001 |
| 6303592 | 7-alkylidene cephalosporanic acid derivatives and methods of using the same Derivatives of 7-alkylidene cephalosporanic acid sulfone and the pharmaceutically active salts thereof are found to be potent inhibitors of ଲ-lactamase enzymes.... | 10/16/2001 |
| 6159706 | Application of enzyme prodrugs as anti-infective agents The present invention provides a method for targeting toxic antimetabolites to gram negative infections. It provides a means of taking advantage of a key disease resistance mechanism to activate these drugs locally, and to overcome the resistance phenotyp... | 12/12/2000 |
| 6150351 | Cephem compounds and pharmaceutical use thereof This invention relates to new cephem compound represented by the following general formula (I): ##STR1## wherein each symbol is as defined in the specification or a salt thereof, which has antimicrobial activity against Helicobacter pylori, and are ... | 11/21/2000 |
| 6090801 | Pharmaceutical compositions containing ceftriaxone and penems Pharmaceutical formulations comprising ceftriaxone in combination with a penem of formula (I) in which R1 is hydrogen or an organic group; R2 is a ring system of formula (II), wherein R4 and R5 are hydrogen or o... | 07/18/2000 |
| 6087355 | Cephalosporin antibiotics The present invention includes novel compounds of formula ##STR1## where A, B, D, and E are selected from the group consisting of carbon, nitrogen and sulfur, R99 is selected from the group consisting of sulfur, SO, SO2, NH, N-a... | 07/11/2000 |
| 6066630 | Cephalosporin antibiotics The present invention includes novel compounds of formula ##STR1## where R99 is selected from the group consisting of sulfur, SO, SO2, NH, N-alkyl, oxygen, C.dbd.C (cis or trans), and C.tbd.C, and R12 is ##STR2##... | 05/23/2000 |
| 6030965 | Cephalosporin antibiotics The present invention includes novel compounds of formula where A, B, D, and E are selected from the group consisting of carbon, nitrogen and sulfur, R99 is selected from the group consisting of sulfur, SO, S02, NH, N-alkyl, oxygen, ... | 02/29/2000 |
| 6025352 | Cephalosporin antibiotics The present invention includes novel compounds of formula ##STR1## where G, H, J, L and M are carbon or nitrogen, R99 is selected from the group consisting of sulfur, SO, SO2, NH, N-alkyl, oxygen, C.tbd.C (cis or trans), and C.t... | 02/15/2000 |
| 5994340 | Azetidinone derivatives as ଲ-lactamase inhibitors New 2-oxo-1-azetidine sulfonic acid derivatives with an aminoalkyl substituted "anti" (E-isomer) oxyimino group in the acylamino substituent at the 3 position of the monobactam ring. These compounds are potent inhibitors of bacterial ଲ-lactamases. T... | 11/30/1999 |
| 5945414 | Process for the preparation of new intermediates useful in the synthesis of cephalosporins Cefazolin, cefazedone, cefoperazone, cefamandole, cefatrizine or ceftriaxone is prepared by reacting glutaryl 7-ACA of the formula: ##STR1## with a compound of formula (II): R--SH (II) wherein R is 5-me... | 08/31/1999 |
| 5728691 | Quinolonylcarboxamidocephalosporin derivatives and pharmaceutical compositions containing them Derivatives of 7-aminoceph-3-em-4-carboxylic acid with 6-fluoroquinolone derivatives in which the cephem and 6-fluoroquinolone moieties are bound to each other through a carboxamido bond as well as the pharmaceutical compositions containing them are descr... | 03/17/1998 |
| 5710146 | Cephem derivatives and processes for their manufacture Cephem derivatives of the general formula ##STR1## in which the R2 O group is in the syn-position, a process for their manufacture and pharmaceutical formulations which are active against bacterial infections and contain these compounds.... | 01/20/1998 |
| 5705496 | Crystalline benzathine salt of cefonicid and its preparation The present invention relates to benzathine salts of cefonicid, a member of the cephalosporin family of antibiotics, which are crystalline. ##STR1##... | 01/06/1998 |
| 5698547 | Cephalosporin antibiotics The present invention includes novel (7R)-7-(acylamino)-3-(arylthio)-3-cephem-4-carboxylic acids or their pharmacologically acceptable salts which exhibit antibiotic activity against a wide spectrum of organisms including organisms which are resistan... | 12/16/1997 |
| 5698544 | Cephem compound, process for producing the compound, and antimicrobial composition containing the same The present invention provides a cephem compound having a high antimicrobial activity against various pathogenic bacteria. The cephem compound of the invention is represented by the formula ##STR1## wherein Q represents CH or N, R1 represents a... | 12/16/1997 |
| 5635501 | Alphalosporins and 1-carba-1-dethia cephalosporins Compound of formula (I) or salts thereof wherein R1 is hydrogen, methoxy or formamido; R2 is an acyl group; CO2 R3 is a carboxy group or a carboxylate anion, or R3 is a readily removable carboxy prote... | 06/03/1997 |
| 5629306 | 7-alkylidene cephalosporanic acid derivatives and methods of using the same Derivatives of 7-alkylidene cephalosporanic acid sulfone and the pharmaceutically active salts thereof are found to be potent inhibitors of ଲ-lactamase enzymes.... | 05/13/1997 |
| 5593986 | Cephalosporin antibiotics The present invention includes novel (7R)-7-(acylamino)-3-(arylthio)-3-cephem-4-carboxylic acids or their pharmacologically acceptable salts which exhibit antibiotic activity against a wide spectrum of organisms including organisms which are resistan... | 01/14/1997 |
| 5587373 | 2-acyloxycephem derivatives The present invention provides cephalosporin sulphones of formula (I) and the pharmaceutically and veterinarily acceptable salts thereof: ##STR1## wherein n is one or two: A and B are both or each independently hydrogen or an organic radical; R1... | 12/24/1996 |
| 5580865 | 2,2-disubstituted cephem sulphones The present invention provides cephalosporin sulphones or formula (I), and pharmaceutically or veterinarily acceptable salts thereof; ##STR1## wherein n is zero, one or two; R1 is hydrogen, halogen or an optionally substituted C1 | 12/03/1996 |
| 5571804 | Cephalosporin antibiotics Cephalosporin compounds of formula (I): ##STR1## wherein: R1 is a hydrogen or an amino protecting group; R2 and R3 are, independently, a hydrogen or a hydroxy protecting group, or form together a cyclic diol protecting gro... | 11/05/1996 |
| 5446037 | 2-[(substituted) methylene]cephalosporin sulfones as antiinflammatory, antidegenerative and antithrombin agents This invention relates to 2-[(substituted)methylene]cephalosporin sulfones and in particular 2-[(heteroaryl substituted)methylene]cephalosporin sulfones which are effective elastase inhibitors as well as effective thrombin inhibitors and therefore are use... | 08/29/1995 |
| 5439904 | 2-spiro(2'-spirocycloalkyl)cyclopropyl cephalosporin sulfones as antiinflammatory and antigenerative agents 2-spiro (2'-spirocycloalkyl) cyclopropyl cephalosporin sulfone compounds, methods of treating patients for elastase inhibition, and processes for preparing such compounds.... | 08/08/1995 |
| 5373000 | 7Beta-(thiadiazolyl)-2-iminoacetamido-3cephem compounds A cephalosporin derivative represented by the formula: ##STR1## wherein R1 represents a lower alkyl group, and A is selected from: a group of the following formula: ##STR2## where R2 and R3 are the same or differ... | 12/13/1994 |
