Bizarre Patents
A method for inducing cats to exercise consists of directing a beam of invisible light produced by a hand-held laser apparatus onto the floor or wall.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7279582 | Retroviral protease inhibiting compounds A compound of the formula: is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed. ... | 10/09/2007 |
| 7241756 | Combinations of dipeptidyl peptidase IV inhibitors and other antidiabetic agents for the treatment of diabetes mellitus A method for the treatment of diabetes mellitus, especially Type 2 diabetes and conditions associated with diabetes mellitus in a mammal such as a human, which method comprises administering an effective, non-toxic and pharmaceutically acceptable amount of a dipepti... | 07/10/2007 |
| 7135465 | Sustained release beadlets containing stavudine Extended dosage forms of stavudine are provided comprising beadlets formed by extrusion-spheronization and coated with a seal coating. The beadlets are also coated with a modified release coating such that a hard gelatin capsule containing such beadlets will provide... | 11/14/2006 |
| 7112582 | Bicyclic 6-alkylidene-penems as β-lactamase inhibitors The present invention provides a compound of formula I, pharmaceutical compositions and the use thereof for the treatment of bacterial infection or disease in a patient in need thereof. wherein one of A and B den... | 09/26/2006 |
| 7081445 | Cyclosporin galenic forms Pharmaceutical compositions comprising a cyclosporin as active ingredient, a fatty acid triglyceride, a glycerol fatty acid partial ester or propylene glycol or sorbitol complete or partial ester, preferably, and a tenside having an HLB of at least 10. ... | 07/25/2006 |
| 7078397 | Combinations of dipeptidyl peptidase IV inhibitors and other antidiabetic agents for the treatment of diabetes mellitus Disclosed is a method for the treatment of diabetes mellitus, especially Type 2 diabetes and conditions associated with diabetes mellitus in a mammal such as a human, which method comprises administering an effective, non-toxic and pharmaceutically acceptable amount... | 07/18/2006 |
| 7071201 | Quinoline derivatives A novel compound of the formula: wherein A, B, C, D, T, Y, and Z represent each methine or nitrogen; R1, R2, R3, R4, and R5 represent each a substituent; n represe... | 07/04/2006 |
| 7018997 | Tricyclic 6-alkylidene-penems as β-lactamase inhibitors The present invention provides a compound of formula I, pharmaceutical compositions and the use thereof for the treatment of bacterial infection or disease in a patient in need thereof. wherein one of A and B denotes hy... | 03/28/2006 |
| 6489316 | 6-(spirocyclopropyl) penicillanic acid 4, 4-dioxides The 6-(spirocyclopropyl)-penicillanic acid 4,4-dioxides of the general Formula (I): ##STR1## as defined herein above which exhibit beta-lactamase inhibiting activity, use of such compounds in combination with beta-lactam antibiotics for inhibiting be... | 12/03/2002 |
| 6472383 | Pharmaceutical formulations A pharmaceutical formulation comprises, in combination with a penem of formula (I): ##STR1## in which: R1 is hydrogen or an organic substituent group; R2 is a fused bicyclic heterocyclic ring system of general formula: ##STR2## wher... | 10/29/2002 |
| 6426342 | Use of ଲ-lactamase inhibitors as neuroprotectants Novel neuroprotectant methods are described. ଲ-Lactamase inhibitors are used to prevent or reduce loss of neuronal cells and neuronal cell function in patients afflicted with or susceptible to disease states or conditions known to result in or cause... | 07/30/2002 |
| 6180621 | Method and treatment using 1-methylcarbapenem derivatives as an anti-helicobacter pylori agent A method for the prophylaxis or treatment of infectious diseases caused by helicobacter pyloir, by administering a pharmacologically effective amount of a 1-methoylcarbapenem coumpund of formula (I) or a pharmacologically acceptable salt or ester thereof:... | 01/30/2001 |
| 5945413 | Aspartyl protease inhibitors This invention relates to a novel class of compounds that are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of aspartyl protease inhibitors characterized by specific structural and physicochemical features. This ... | 08/31/1999 |
| 5939066 | Pharmaceutical formulations A pharmaceutical formulation comprises, in combination with a penem of formula (I): ##STR1## in which: R1 is hydrogen or an organic substituent group; R2 is a fused bicyclic heterocyclic ring system of general formula: ##STR2## ... | 08/17/1999 |
| 5911985 | Pharmaceutical formulations containing a ଲ-lactamase inhibiting penem in combination with ଲ-lactam antibiotic and their use in the treatment of bacterial infections A pharmaceutical formulation comprises, in combination with a penem of formula (I), in which: R1 is hydrogen or an organic substituent group; R2 is a fused bicyclic heterocyclic ring system of general formula (a), wherein R4 | 06/15/1999 |
| 5776455 | Pharmaceutical formulations A pharmaceutical formulation comprises, in combination with a penem of formula (I): ##STR1## in which: R1 is hydrogen or an organic substituent group; R2 is a fused bicyclic heterocyclic ring system of general formula: ##STR2## ... | 07/07/1998 |
| 5637580 | Antimicrobial penem-quinolones Compounds of structure: ##STR1## as well as their pharmaceutically-acceptable salts and biohydrolyzables esters, and hydrates thereof, are effective antiinfective agents, useful in treating and preventing infection.... | 06/10/1997 |
| 5480880 | Penem derivatives The invention provides compounds of the general formula I ##STR1## wherein R1 is a hydrogen atom, a negative charge or an ester residue; R is: a) --(CH2)n --A--CO2 H, --(CH2)n--A--SO3 H or ... | 01/02/1996 |
| 5008257 | Brain-specific drug delivery The subject compounds, which are adapted for the site-specific/sustained delivery of centrally acting drug species to the brain, are: (a) compounds of the formula [D-DHC] (I) wherein [D] is a centrally acting drug ... | 04/16/1991 |
| 4923856 | Penem compounds Compounds of the general formula (II): ##STR1## and pharmaceutically acceptable salts and in-vivo hydrolysable esters thereof, in which R denotes a hydrogen atom or an in vivo hydrolysable acyl group; and the wavy line denotes either the E- or Z-isometric... | 05/08/1990 |
| 4876251 | Tricyclic penam compounds, their production and their use The compounds, having a 4,10-dioxo-3-oxa-7-thia-1-azatricyclo[6,2,0,02,6 ]decane-2-carboxylic acid skeleton as the base structure, their esters and their salts, are useful antibacterial agents.... | 10/24/1989 |
| 4826833 | 6-(Substituted)methylene-penicillanic and 6-(substituted)hydroxymethylpenicillanic acids and derivatives thereof Beta-lactamase inhibiting compounds of the formula ##STR1## or a pharmaceutically acceptable acid addition or carboxylate salt thereof; where n is zero, 1 or 2; X3 is H or Br, R1 is H, the residue of certain carboxy-protecting g... | 05/02/1989 |
| 4782050 | 6-beta(substituted)-(S)-hydroxymethylpenicillanic acids and derivatives thereof Antibacterial penicillins of the formula ##STR1## or a pharmaceutically acceptable salt thereof wherein R1 is a heterocyclic group and R is hydrogen, the residue of certian carboxy protecting groups or the residue of an ester group readily... | 11/01/1988 |
| 4731360 | Acylcarnitines as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal compartments Acylcarnitine used as a nasal, buccal, sublingual and vaginal drug absorption enhancing vehicle for poorly absorbed drugs.... | 03/15/1988 |
| 4729989 | Enhancement of absorption of drugs from gastrointestinal tract using choline ester salts Choline ester salts are used as drug absorption enhancing agents for orally and rectally administered drugs.... | 03/08/1988 |
| 4692441 | Chorine esters as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal cavities Choline esters are used as drug absorption enhancing agents for drugs which are poorly absorbed from the nasal, oral, and vaginal cavities.... | 09/08/1987 |
| 4650794 | 6-(1-hydroxyethyl)-2-carbamimidoyl-pen-2-em-3-carboxylic acids Disclosed are 6-(1-hydroxyethyl)-2-carbamimidoyl-pen-2-em-3-carboxylic acids (I) having the representative structure: ##STR1## wherein: A is a direct, single bond connecting the indicated S and C atoms, or A is a cyclic or acyclic connecting group se... | 03/17/1987 |
| 4614737 | 2-dioxacycloalkylthiopenem derivatives Certain 2-dioxacycloalkylthio-2-penem-3-carboxylic acid compounds are useful as antibacterials for treating mammals and have the formula ##STR1## or a pharmaceutically acceptable salt thereof, wherein: R is ##STR2## A is carbonyl, methylene or t... | 09/30/1986 |
| 4612337 | Method for preparing infection-resistant materials An infection-resistant polymeric material, such as polytetrafluoroethylene, for use on or within a human or animal body, for example, in the form of a vascular graft, can be prepared by an improved method which comprises the following sequence of steps: (... | 09/16/1986 |
| 4585767 | Antibacterial penem derivatives Antibacterially active penem compounds and salts of the formula ##STR1## wherein R is hydrogen or an esterifying group, R2 is hydrogen, hydroxy, or protected hydroxy, and R1 is phenyl, naphthyl, thienyl, pyridyl, quinolyl, or is... | 04/29/1986 |
| 4582829 | Antibacterial 6'-(2-amino-2-[4-acyloxyphenyl]acetamido)penicillanoyloxymethyl penicillanate 1,1-dioxide compounds 6-(2-Amino-2-[4-acyloxyphenyl]acetamido)penicillanoyloxymethyl esters of penicillanic acid 1,1-dioxide are useful as antibacterial agents. Derivatives of the aforesaid antibacterial agents which have an amino protecting group on the amino function in the ... | 04/15/1986 |
| 4540687 | Antibacterial 6'-(2-amino-2-[4-acyloxyphenyl]acetamido)penicillanoyloxymethyl penicillanate 1,1-dioxide compounds 6-(2-Amino-2-[4-acyloxyphenyl]acetamido)penicillanoyloxymethyl esters of penicillanic acid 1,1-dioxide are useful as antibacterial agents. Derivatives of the aforesaid antibacterial agents which have an amino protecting group on the amino function in the ... | 09/10/1985 |
| 4537886 | ଲ-lactam antibacterial agents and compositions containing them A compound of formula (1) or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof: ##STR1## wherein R1 is phenyl, substituted phenyl or a 5- or 6-membered heterocyclic ring containing up to three heteroatoms selected fr... | 08/27/1985 |
| 4524073 | ଲ-Lactam compounds A compound of formula (I) or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof: ##STR1## wherein R represents an alkyl or aralkyl group, substituted on an alkyl carbon atom other than that adjacent to --NH-- group, with one or ... | 06/18/1985 |
| 4505915 | 6-N-Heterocyclyl penicillins This invention relates to a new class of penicillins (I) and their pharmaceutically acceptable salts and esters which are useful as antibiotics: ##STR1## wherein the stylized radical (hereafter referred to as R'): ##STR2## attached to the 6... | 03/19/1985 |
| 4503040 | 6-(Aminoacyloxymethyl)penicillanic acid 1,1-dioxides as beta-lactamase inhibitors Beta-lactamase inhibitors which are aminoacid esters of 6-alpha- and 6-beta-(hydroxymethyl)pencillanic acid 1,1-dioxides; pharmaceutically-acceptable salts thereof; conventional esters thereof which are hydrolyzable in vivo; bis-methanediol esters thereof... | 03/05/1985 |
| 4485110 | ଲ-Lactam compounds, and use A class of 6-alkylidene penem compounds of formula (II) have antibacterial and ଲ-lactamase inhibitory properties: ##STR1## where R1 and R2 represent hydrogen or optionally substituted hydrocarbon or heterocyclic, and R | 11/27/1984 |
| 4462934 | Bis-esters of dicarboxylic acids with amoxicillin and certain hydroxymethylpenicillanate 1,1-dioxides Antibacterial bis-esters of 1,4-cyclohexanedicarboxylic acids and alkane dicarboxylic acids wherein the ester moieties are derived from different alcohols; one alcohol being hydroxymethylpenicillanate 1,1-dioxide, or the 6-beta-hydroxymethyl or the 6-alph... | 07/31/1984 |
| 4457924 | 1,1-Alkanediol dicarboxylate linked antibacterial agents Useful antibacterial agents in which a penicillin and/or a beta-lactamase inhibitor are linked via 1,1-alkanediol dicarboxylates are of the formula ##STR1## where A is the residue of certain dicarboxyic acids, R3 is H or (C1 -C | 07/03/1984 |
| 4452796 | 6-Aminoalkylpenicillanic acid 1,1-dioxides as beta-lactamase inhibitors Beta-lactamase inhibitors which are 6-alpha- and 6-beta-(aminomethyl) and (1-aminoethyl)pencillanic acid 1,1-dioxides; pharmaceutically-acceptable salts thereof; conventional esters thereof which are hydrolyzable in vivo; bis-methanediol esters thereof; o... | 06/05/1984 |
