Did You Know...
...In 1790, the cost to obtain a patent was between $4 and $5.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8173630 | Multipodal tethers for high-density attachment of redox-active moieties to substrates This invention provides redox-active molecules attached to polypodal (e.g., bipodal, tripodal, quadrapodal, pentapodal, etc.) tethers that can be used for attachment of the redox-active molecules to a substrate (e.g., an electrode). The tethered redox-active molecul... | 05/08/2012 |
| 8163726 | Method of inhibiting choroidal neovascularization The present invention relates to compositions and methods for inhibiting unwanted angiogenesis, particularly those of ocular tissues. The treatment, inhibition, and/or prevention of choroidal neovasculature (CNV) is provided, along with an animal model for CNV and i... | 04/24/2012 |
| 8158615 | Anti-viral composition for the topical treatment of Herpes Labialis (cold sores) and method for use thereof A composition for the treatment of Herpes Labialis which contains CTC-96 as the active ingredient is disclosed. Methods for using the composition are also disclosed. The composition may be used as a topical ointment. ... | 04/17/2012 |
| 8153620 | Photoactive metal nitrosyls for blood pressure regulation and cancer therapy Disclosed are nitric oxide delivery agents and methods of their use, more specifically to photoactive compounds, which are able to perform targeted delivery of nitric oxide in vitro and in vivo and are useful for medicinal applications including, but not limited, to... | 04/10/2012 |
| 8106038 | Method for reducing or preventing PDT related inflammation This invention relates generally to the field of pharmacotherapeutics and the use of photodynamic therapy (“PDT”). In particular, the invention provides a method for reducing or preventing the effects of inflammation arising from normal dose photodynamic therapy... | 01/31/2012 |
| 8106039 | Metal complex phosphatidyl-inositol-3-kinase inhibitors Provided are novel organometallic compounds that inhibit PI3K lipid kinase and phospho-AKT in human melanoma cells, and also inhibit the migration of melanoma cells. The present invention is also directed to methods for inhibiting cancer cell proliferation, migratio... | 01/31/2012 |
| 8097609 | Swallowtail motifs for imparting water solubility to porphyrinic compounds Porphyrinic compounds that contain solubilizing groups are described, along with methods of making and using the same and compositions comprising such compounds. Examples of such compounds include compounds of Formula (I) wherein: Z is a porphyrinic macrocyclic, Alk... | 01/17/2012 |
| 8067405 | Superoxide dismutase mimics for the treatment of ocular disorders and diseases The use of SOD mimics, particularly Mn(III) salen SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed. ... | 11/29/2011 |
| 8067404 | Phthalocyanine derivatives, process for their preparation, pharmaceutical compositions containing them and their use Phthalocyanine derivatives are described having photosensitizing characteristics and high solubility in water, useful for photodynamic treatment of bacterial infections, in particular infections generated by Gram-negative bacteria. ... | 11/29/2011 |
| 8034803 | Photodynamic therapy of occult age-related macular degeneration The invention relates to the selection and treatment of subjects afflicted with occult choroidal neovascular lesions, including subjects with age-related macular degeneration, by use of photo dynamic therapy (PDT). ... | 10/11/2011 |
| 8003635 | Superoxide dismutase mimics for the treatment of ocular disorders and diseases The use of SOD mimics particularly pentaazacycle Mn(II) complex SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed. ... | 08/23/2011 |
| 7964588 | Method for the treatment of psoriasis A method for the therapeutic treatment of psoriasis by the administration of an anti-psoriasis effective amount of Doxivir (CTC-96) is discloses. ... | 06/21/2011 |
| 7960371 | High-purity large-scale preparation of stannsoporfin Large scale (bulk) compositions comprising high-purity stannsoporfin are disclosed, as well as methods of synthesizing such compositions. ... | 06/14/2011 |
| 7947674 | Meso-substituted porphyrins Meso-substituted porphyrins of general formula (I) suitable for the use as photosensitizing agents, in particular in photodynamic therapy, are herein described. ... | 05/24/2011 |
| 7915248 | Boronated metal-phthalocyanines, process for their preparation, pharmaceutical compositions comprising them and use thereof The present invention relates to metal-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the axial positions of metal-phthalocyanine nucleus; moreover it refers to the process for their preparati... | 03/29/2011 |
| 7842682 | Boronated metal-phthalocyanines, process for their preparation, pharmaceutical compositions comprising them and use thereof The present invention relates to meta 1-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the peripheral positions of meta 1-phthalocyanine nucleus; moreover it refers to the processes for their ... | 11/30/2010 |
| 7825108 | Method of printing an IR-absorbing dye onto a substrate A method of printing an IR-absorbing dye onto a substrate whilst minimizing visible coloration of the substrate. The method comprises: (i) preselecting the dye from a metal-cyanine of formula (I): Q1, Q2 | 11/02/2010 |
| 7820644 | Substituted porphyrins The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating cellular levels of oxidants and thereby processes in which such oxidants are a participant. The invention also... | 10/26/2010 |
| 7759333 | Superoxide dismutase mimics for the treatment of ocular disorders and diseases The use of SOD mimics particularly pentaazacycle Mn(II) complex SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed. ... | 07/20/2010 |
| 7754706 | Superoxide dismutase mimics for the treatment of ocular disorders and diseases The use of SOD mimics, particularly Mn(III) salen SOD mimics, for the treatment of AMD, DR, and retinal edema is disclosed. ... | 07/13/2010 |
| 7749991 | Substituted metal-phthalocyanines, their preparation and the use thereof The present invention is directed to metal-phthalocyanines of general formula (I) to the corresponding conjugates, the processes for their preparation and use in the photodynamic therapy of microbial infections (viral, bacterial and mycotic), tumor, pre-cancerous an... | 07/06/2010 |
| 7704987 | β-amyloid peptide inhibitors The present invention relates to compounds which inhibit the binding of metal ions to a region in the N-terminal loop of the β-amyloid peptide which includes a cluster of histidine residues. In addition, the invention relates to pharmaceutical compositions includin... | 04/27/2010 |
| 7671046 | Metal complex protein kinase inhibitors This inventive subject matter relates to novel metal complex protein kinases inhibitors, methods for making such compounds, and methods for using such compounds for treating diseases and disorders mediated by kinase activity. ... | 03/02/2010 |
| 7648977 | Pharmaceutical composition having a ruthenium oxalato compound and method of using the same The present invention relates to a pharmaceutical composition comprising one or more of the following ruthenium oxalato compounds I, II, III and IV as an active ingredient. The pharmaceutical composition can be used for the treatment of viral-infected patients or pr... | 01/19/2010 |
| 7642250 | N-benzyl substituted pyridyl porphyrin compounds and methods of use thereof The present invention relates to N-Benzyl-Substituted Pyridyl Porphyrin Compounds and compositions comprising an effective amount of N-Benzyl-Substituted Pyridyl Porphyrin Compounds. The N-Benzyl-Substituted Pyridyl Porphyrin Compounds include compounds of the follo... | 01/05/2010 |
| 7582623 | Photoactive metal nitrosyls for blood pressure regulation and cancer therapy Disclosed are nitric oxide delivery agents and methods of their use, more specifically to photoactive compounds, which are able to perform targeted delivery of nitric oxide in vitro and in vivo and are useful for medicinal applications including, but not limited, to... | 09/01/2009 |
| 7579338 | Methods and compositions for treating atheroma, tumors and other neoplastic tissues The radiation sensitization potential of a candidate compound can be screened by determine its ability to generate one or more reactive oxygen species under appropriate conditions. Compounds determined to have radiation sensitization potential are employed in method... | 08/25/2009 |
| 7572782 | Use of targeted oxidative therapeutic formulation in bone regeneration A pharmaceutical formulation and its use. The pharmaceutical formulation contains peroxidic species or reaction products resulting from oxidation of an alkene, such as geraniol, by an oxygen-containing oxidizing agent, such as ozone; a penetrating solvent, such as d... | 08/11/2009 |
| 7547689 | Methods and compositions for treating atheroma, tumors and other neoplastic tissues Compositions comprising motexafin gadolinium, as well as methods for using these compositions in the treatment of brain metastases, are described herein. ... | 06/16/2009 |
| 7528125 | Water-soluble zinc ionophores, zinc chelators, and/or zinc complexes and use for treating cancer Disclosed herein are novel zinc ionophores, zinc chelators and/or zinc complexes with enhanced aqueous solubility. Methods of treating cancer using at least one zinc ionophore and/or zinc chelator are also disclosed. Also disclosed herein are compositions and method... | 05/05/2009 |
| 7521440 | Targeted oxidative therapeutic formulation Pharmaceutical formulation, its method of preparation, and its use. The pharmaceutical formulation contains peroxidic species or reaction products resulting from oxidation of an alkene, such as geraniol, by an oxygen-containing oxidizing agent, such as ozone; a pene... | 04/21/2009 |
| 7511031 | Noninvasive vascular therapy The present invention is drawn to apparatus for transcutaneous photodynamic therapy (“PDT”) of a target tissue or compositions in a mammalian subject, which includes a light source that is external to the subject and is selected from among one or a plurality of ... | 03/31/2009 |
| 7470677 | Oxidant scavengers The present invention relates, in general, to a method of modulating physiological and pathological processes and, in particular, to a method of modulating intra- and extracellular levels of oxidants and thereby processes in which such oxidants are a participant. Th... | 12/30/2008 |
| 7449454 | Metallotexaphyrin derivatives Novel derivatives of metallotexaphyrins are prepared by modifying the apical ligands associated with the central metal component of a metallotexaphyrin. ... | 11/11/2008 |
| 7414044 | Use of targeted oxidative therapeutic formulation in treatment of type 2 diabetes A pharmaceutical formulation and its use. The pharmaceutical formulation contains peroxidic species or reaction products resulting from oxidation of an alkene, such as geraniol, by an oxygen-containing oxidizing agent, such as ozone; a penetrating solvent, such as d... | 08/19/2008 |
| 7410960 | Metal complexes and therapeutic uses thereof A compound of formula I or a salt thereof [ML1L2]2+ (I) where M is selected from the group consisting of platinum(II), palladium (II) and copper(II); L1 is an intercalator moiety; and L2 | 08/12/2008 |
| 7384927 | Alkylated porphyrins as pesticides acting both in the presence and absence of light An insecticidal composition comprising at least one compound of the tetrapyrrole series having at least one hydrocarbon chain at least 12 carbon atoms long as a peripheral substituent, wherein the compound of the tetrapyrrole series is selected from porphyrins, chlo... | 06/10/2008 |
| 7375215 | Compounds for PDT A tetrakis(hydroxyphenyl)chlorin, bacteriochlorin or isobacteriochlorin, derivatised at one or more of the hydroxy groups by addition reaction with a diisocyanate, diisothiocyanate or isocyanate-isothiocyanate at one isocyanate or isothiocyanate group thereof, the o... | 05/20/2008 |
| 7371870 | Benzimidazolone compound There are provided benzimidazolone compounds that provide a plurality of hues from a single structural formula, and are useful as pigments that offer superior dispersibility in binder resins, as well as benzimidazolone compounds that are useful as pigments, and show... | 05/13/2008 |
| 7371742 | Porphyrin derivatives for photodynamic therapy This invention relates to porphyrin compounds used to destroy or impair the functioning of a target biological material in photodynamic therapy, in particular against virus, tumoral cells, bacteria, tumorous tissues. The invention also relates to compositions contai... | 05/13/2008 |
