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| Number | Title | Issue Date |
| 4107303 | Antihypertensive hexafluorohydroxyisopropyl benzazepines and benzazocines Hexafluorohydroxyisopropyl: -tetrahydroquinolines, -benzazepines, and -benzazocines, such as 2,3,4,5-tetrahydro-1-(1-oxopropyl)-,-bis(trifluoromethyl)-1H -1-benzazepine-7-methanol useful as antihypertensives.... | 08/15/1978 |
| 4101671 | Aminobenzyl-amines and salts thereof Compounds of the formula ##STR1## wherein R1 is hydrogen or aliphatic or aromatic carboxylic acyl, R2 is hydrogen, chlorine or bromine, R3 is fluorine, alkyl of 1 to 4 carbon atoms, trifluoromethyl, cyano, carbamoyl, carbo... | 07/18/1978 |
| 4100277 | 4,1-Benzoxazonine derivatives and process therefor 4,1-Benzoxazonine derivatives characterized by having an alkyl radical at the 3-position as well as being further substituted at the 3-position are disclosed. The derivatives are optionally further substituted at positions 1,2,6 and 7. The 4,1-benzoxazine... | 07/11/1978 |
| 4092433 | Quinone derivatives as molluscicides Covers a method for the control of mollusks by treating said mollusk or its habitat with a compound of the formula: ##STR1## where Z is selected from the group consisting of hydrogen, halo and cyano; X is selected from the group consisting of ##... | 05/30/1978 |
| 4089953 | 1,5-Benzodiazocines 1,5-Benzodiazocines of the general formula ##STR1## their 5N-oxides, and acid addition salts thereof. In the above formula R1 =H, Halogen, CF3, --CN, --NO, C1-6 alkyl, C1-6 alkoxy or C1-6 alkylth... | 05/16/1978 |
| 4085210 | Novel morpholine derivatives and the treatment of mental depression Novel morpholine compounds of the formula: ##STR1## wherein R1 represents hydrogen or C1 -C4 alkyl, R2 represents hydrogen, C1 -C4 alkyl, C3 -C5 alkenyl, C3 | 04/18/1978 |
| 4076799 | Method of inhibiting skin irritation A method of inhibiting or reducing the irritation of skin resulting from allergic contact dermatitis, caused by contact with natural or synthetic allergenic agents, e.g. poison ivy, and dinitrochlorobenzene, respectively, is described. The method comprise... | 02/28/1978 |
| 4069329 | N2 -Naphthalenesulfonyl-L-arginine derivatives, and the pharmaceutically acceptable acid addition salts thereof N2 -naphthalenesulfonyl-L-arginine esters and amides having the formula ##STR1## or the acid addition salts thereof with a pharmaceutically acceptable acid, wherein R is selected from the class consisting of (1) alkoxy, alkenyloxy, cy... | 01/17/1978 |
| 4069323 | N2 -substituted-L-arginine derivatives and the pharmaceutically acceptable acid addition salts thereof N2 -substituted-L-arginine esters and amides, and the pharmaceutically acceptable acid addition salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis.... | 01/17/1978 |
| 4066759 | N2 -naphthalenesulfonyl-L-arginine derivatives, and the pharmaceutically acceptable acid addition salts thereof N2 -naphthalenesulfonyl-L-arginine esters and amides having the formula ##STR1## or the acid addition salts thereof with a pharmaceutically acceptable acid, wherein R is selected from the class consisting of (1) alkoxy, alkenyloxy, cy... | 01/03/1978 |
| 4066758 | N2 -naphthalenesulfonyl-L-arginine derivatives, and the pharmaceutically acceptable acid addition salts thereof N2 -naphthalenesulfonyl-L-arginine esters and amides having the formula ##STR1## or the acid addition salts thereof with a pharmaceutically acceptable acid, wherein R is selected from the class consisting of (1) alkoxy, alkenyloxy, cy... | 01/03/1978 |
| 4062963 | N2 -naphthalenesulfonyl-L-arginine derivatives, and the pharmaceutically acceptable acid addition salts thereof N2 -naphthalenesulfonyl-L-arginine esters and amides having the formula ##STR1## or the acid addition salts thereof with a pharmaceutically acceptable acid, wherein R is selected from the class consisting of (1) alkoxy, alkenyloxy, cy... | 12/13/1977 |
| 4061746 | Lactamimide inhibitors of gastrointestinal hypersecretion A method of treating gastrointestinal hypersecretions which comprises administering substituted lactamimide derivatives.... | 12/06/1977 |
| 4053599 | Piperazionalkylpyrrolobenzoxazalkanes Novel piperazinoalkylpyrrolobenzoxazalkanes, physiologically tolerable acid addition salts thereof and a method of preparing same are described. These compounds are useful as antihypertensive agents.... | 10/11/1977 |
| 4053600 | Tricyclic 1,2,4-triazolo-quinazolines The invention discloses 5-substituted-1,2,4-triazolo[4,3-c]quinazolines and 1,2,4-triazolo[1,5-c]quinazolines having pharmacological activity in animals and useful, for example, as hypotensive and anti-inflammatory agents. The compounds may be prepared, f... | 10/11/1977 |
| 4053596 | Indanpentol derivatives Compounds are provided having the structure ##STR1## wherein n is 1, 2 or 3, m is 0, 1 or 2, R1, R2, R3, R4 and R5 may be the same or different and can be hydrogen, lower alkyl, halo-lower alkyl,... | 10/11/1977 |
| 4051242 | Substituted N-acyl-N"-(3-amino-2-cyanoacryloyl-)formamidrazones Therapeutically-active and pharmacologically-acceptable N-acyl-N" -(3-amino-2-cyanoacryloyl)-formamidrazones and their pharmaceutically-acceptable acid-addition salts inhibit xanthine oxidase and are useful as the active ingredient in medicaments for the ... | 09/27/1977 |
| 4049818 | 3-Chloro-1,3-oxazines or oxazolidines as antibacterial agents There is provided, novel 3-chloro-tetrahydro-1,3-oxazine or oxazolidine compounds, exhibiting antibacterial activity and being of low chlorine potential of the formula: ##STR1## wherein each of R1 and R2, which may be the same o... | 09/20/1977 |
| 4048317 | Chroman derivatives Anti-hypertensive derivatives of trans-3-hydroxy-4-amino-chroman, their preparation from amines and chroman epoxide derivatives, and pharmaceutical compositions containing such anti-hypertensive derivatives for reducing blood pressure in mammals including... | 09/13/1977 |
| 4032640 | 4H-Benzo[4,5]cyclohepta[1,2-b]thiophenes This invention provides new compounds of formula I, ##STR1## wherein R1 is hydrogen, halogen of atomic number from 9 to 35, or alkyl or alkoxy of 1 to 4 carbon atoms, R2 is hydrogen or alkyl of 1 to 4 carbon atoms, R3 is h... | 06/28/1977 |
| 4031215 | Streptovaricinone C derivatives as antibiotics Streptovaricinone C derivatives of the formula ##STR1## wherein Z is a C1.sub.-12 alkyl, an aryl, a hydroxyalkyl, an alkenyl, a ketonyl, a furyl-oxoalkyl, a thienyl-oxoalkyl, a phenacyl, a carbamylalkyl, a benzyl, a phenoxyalkyl, a cyanoal... | 06/21/1977 |
| 4028466 | Analgesic compositions comprising dextro-propoxyphene and benzodiazepine and process Analgesic compositions having a remarkably high analgesic activity and a process for obtaining an analgesic effect are provided, in which the active components are dextro-propoxyphene and at least one of certain benzodiazepines. The analgesic activity of ... | 06/07/1977 |
| 4015015 | Chemical fire alarm A system for warning people of a fire hazard comprising a flammable substrate having bound thereto a non-vaporous organic compound of molecular weight below 400, which forms a respiratory irritant upon being vaporized. The organic compound remains bound t... | 03/29/1977 |
| 4011318 | Metal salts of 1,1,5,5-tetrasubstituted dithiobiurets as population control agents Disclosed are compounds useful as population control agents which are metal salts of 1,1,5,5-tetra-substituted dithiobiurets of the formula ##STR1## in which R1, R2, R3 and R4, when taken independently of e... | 03/08/1977 |
| 3996374 | Isoindole derivatives as appetite suppressants Isoindole derivatives of the formula ##STR1## wherein R1 -R6, A and Z are as hereinafter described. The isoindole derivatives are useful as appetite suppressants.... | 12/07/1976 |
| 3995050 | Amino-2 imidazoles Aminoimidazoles of the formula ##SPC1## Wherein R1 is optionally substituted phenyl, R4 is hydrogen or alkyl, R.sub. 5 is hydrogen or methyl and R2 and R3 form, together with the nitrogen atom to which they are ... | 11/30/1976 |
| 3991194 | Heterocyclic esters of benzopyranopyridines Novel heterocyclic esters of benzopyranopyridines represented by the formula ##SPC1## Wherein R1 is hydrogen, lower alkyl, lower alkanoyl, cycloalkyl-lower alkyl, cycloalkyl-lower alkanoyl, lower alkenyl, lower alkynyl, halo-loweralkenyl, ... | 11/09/1976 |
| 3988467 | Aminoacyl compounds The invention relates to new aminoacyl compounds of the formula I, ##SPC1##... | 10/26/1976 |
| 3944667 | Formylazapentadienenitriles Insecticidal, fungicidal and bactericidal substituted formylazapentadienenitriles are prepared by hydrolyzing an azapentadienylidene ammonium salt of the formula ##EQU1##... | 03/16/1976 |
| 3932649 | 2 And 3-substituted-4-(heterocyclic-amino-sulfonyl)benzene sulfonamides as cerebral vasodilators Compounds of the formulae: ##SPC1## And the salts thereof with pharmaceutically acceptable cations wherein R1 is 3-trifluoromethyl, chloro, bromo or fluoro; n and m are each two or three; X is oxygen or sulphur; R2 and R3,... | 01/13/1976 |
| 3932640 | Cyclic N-substituted derivatives of 1,4-benzene disulphonamide Compounds of the formulae: ##SPC1## And the salts thereof with pharmaceutically acceptable cations wherein n and m are each two or three; X is oxygen or sulphur; R2 and R3, when taken separately, are each hydrogen or alkyl having 1 t... | 01/13/1976 |
| 3932639 | 2 And 3-substituted-4-(heterocyclic-amino-sulfonyl)benzene sulfonamides as cerebral vasodilators Compounds of the formulae: ##SPC1## And the salts thereof with pharmaceutically acceptable cations wherein R1 is 3-trifluoromethyl, chloro, bromo or fluoro; n and m are each two or three; X is oxygen or sulphur; R2 and R3,... | 01/13/1976 |
