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Penn Jillette of Penn and Teller fame has patented a "Hydro-Therapeutic Stimulator", which uses a hot tub for stimulation.
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| Number | Title | Issue Date |
| 7884094 | Compounds for the treatment of proliferative disorders The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 ... | 02/08/2011 |
| 7884095 | Method of treating post-surgical acute pain A method is provided for treating pain in patients recovering from post-surgical trauma by administering between about 13 to about 30 mg of diclofenac potassium in a liquid dispersible formulation over a period of at least 24 hours, wherein the daily total amount of... | 02/08/2011 |
| 7879835 | Pharmaceutical composition for preventing and treating metabolic bone diseases containing alpha-arylmethoxyactylate derivatives The present invention relates to a use of a specific alpha-arylmethoxyacrylate derivative, or its pharmacologically acceptable salt or solvate for preventing and treating metabolic bone diseases. ... | 02/01/2011 |
| 7879836 | Pharmaceutical composition comprising a 1-(3-chlorophenyl)-3-alkylpiperazine for treating appetite disorder Use of a 1-(3-chlorophenyl)-3-alkylpiperazine of formula (I), in racemic (R,S) form or in the form of the (S) enantiomer, in which R is a linear or branched alkyl group having from 1 to 3 carbon atoms, or of an addition salt thereof with a pharmaceutically acceptabl... | 02/01/2011 |
| 7879837 | Therapeutic or prophylactic agent for multiple sclerosis A therapeutic or prophylactic agent for multiple sclerosis is disclosed. The therapeutic or prophylactic agent comprises as an effective ingredient a glycine derivative having a specific structure or a pharmaceutically acceptable salt thereof, for example, the below... | 02/01/2011 |
| 7879834 | Spiroindoline modulators of muscarinic receptors The present invention relates to spiroindoline modulators of muscarinic receptors. The present invention also provides compositions comprising such spiroindoline modulators, and methods therewith for treating muscarinic receptor mediated diseases. ... | 02/01/2011 |
| 7875601 | Cancer treatment with epothilones The invention relates to the treatment of a proliferative disease, especially according to certain treatment regimens, with an epothilone, especially with epothilone A and more preferably epothilone B; as well as to the treatment of certain cancers with such an epot... | 01/25/2011 |
| 7875603 | Specific inhibitors for vascular endothelial growth factor receptors The present application describes isoindoles and derivatives thereof, or pharmaceutically acceptable salt forms thereof, which are useful inhibitors of VEGFR. ... | 01/25/2011 |
| 7875602 | Camptothecin derivatives as chemoradiosensitizing agents Camptothecin-based compounds are useful for treating a neoplasm in mammalian subjects by administering such compound to the subjects in combination with radiotherapy, i.e., the treatment of tumors with radioactive substances or radiation from a source external to th... | 01/25/2011 |
| 7875600 | Pyrimidine compounds as purine receptor antagonist Compounds of formula (I); wherein R1 is H or NHZ; R2 is optionally substituted aryl or heteroaryl attached via a carbon atom; R3 is H; optionally substituted C1-C6alkyl, C2-C6alkenyl, C | 01/25/2011 |
| 7867991 | Compositions comprising novel PPAR ligands and anti-hyperlipemic agents Methods are provided for treating or preventing conditions comprising hypertension and dyslipidemia using antihyperlipemic agents and compounds that antagonize the angiotensin II type 1 (AT1) receptor, function as partial or full activators of peroxisome proliferato... | 01/11/2011 |
| 7867992 | Substituted quinolones The invention relates to substituted quinolones and to processes for their preparation as well as to their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegalo... | 01/11/2011 |
| 7867993 | Preparation containing oxidized flavonoid derivatives The invention relates to novel compositions, in particular cosmetic and/or pharmaceutical compositions or food supplements, comprising at least one oxidized flavonoid derivative of the formula I, to novel oxidized flavonoid derivatives, and to novel uses of the oxid... | 01/11/2011 |
| 7863263 | Agent for regeneration and/or protection of nerves An EP2 agonist which may have an EP3 agonistic effect has an effect of regenerating and/or protecting nerves, and is therefore useful as a therapeutic agent for a disease of the peripheral nervous system, such as a lower or upper motor neuron disease, a nerve root d... | 01/04/2011 |
| 7863262 | Nitroxyl progenitors in the treatment of heart failure Administration of an HNO/NO− donating compound, such as Angeli's salt, increases myocardial contractility while concomitantly lowering left ventricular preload in subjects experiencing heart failure. Moreover, administration of the HNO/NO− ... | 01/04/2011 |
| 7858610 | Preventive and/or remedy for lower urinary tract diseases containing EPagonist (1) A preventive and/or a remedy for lower urinary tract diseases such as inflammation in the lower urinary tract, cystitis (interstitial cystitis, etc.) and urethritis; (2) an agent for improving bladder compliance and/or bladder capacity; and (3) an agent for prot... | 12/28/2010 |
| 7858611 | Neurogenesis by modulating angiotensin The instant disclosure describes methods for treating diseases and conditions of the central and peripheral nervous system by stimulating or increasing neurogenesis. The invention includes compositions and methods based on modulation angiotensin activity to stimulat... | 12/28/2010 |
| 7858609 | Solid ganaxolone formulations and methods for the making and use thereof In certain embodiments, the invention is directed to composition comprising stable particles comprising ganaxolone, wherein the volume weighted median diameter (D50) of the particles is from about 50 nm to about 500 nm. ... | 12/28/2010 |
| 7855192 | Macrolactams by engineered biosynthesis Macrolactams are made by feeding aromatic amino acids as replacement starter units to a mutant strain of the geldanamycin-producing microorganism Streptomyces hygroscopicus var. geldanus NRRL 3602, wherein the gene cluster encoding enzymes for the bios... | 12/21/2010 |
| 7842681 | Treatment of myeoproliferative diseases Methods of reducing the number of platelets in mammals and preventing or treating pro-thrombotic conditions and diseases that are characterized by an excess of, or undesired activation of, platelets using inhibitors of anti-apoptotic Bcl-2 family protein members is ... | 11/30/2010 |
| 7833997 | Analogs of benzoquinone-containing ansamycins and methods of use thereof The present invention provides analogs of benzoquinone-containing ansamycins and uses thereof for treating and modulating disorders associated with hyperproliferation, such as cancer. The present invention provides analogs of benzoquinone-containing ansamycins where... | 11/16/2010 |
| 7833996 | Composition and method for controlling rice water weevils The present invention relates to an insecticidal composition comprising i) zeta cypermethrin and ii) a granular fertilizer, and a method for controlling rice water weevil comprising applying an effective amount of the composition to a rice field prior to flooding. | 11/16/2010 |
| 7833995 | Blood flow promoters for cauda equina tissues It is intended to provide highly safe and efficacious blood flow promoters for cauda equina tissues. Among prostaglandin-like compounds having a weak hypotensive effect, compounds having an effect of promoting the blood flow in cauda equina tissues (excluding limapr... | 11/16/2010 |
| 7820643 | Methods of treating fibromyalgia syndrome, chronic fatigue syndrome and pain The present invention provides a method of treating fibromyalgia syndrome (FMS), chronic fatigue syndrome (CFS), and pain in an animal subject. The method generally involves administering a therapeutically effective amount of a dual serotonin norepinephrine reuptake... | 10/26/2010 |
| RE41893 | Epothilone derivatives The present invention relates to epothilone derivatives, having the following formula in which the variables G, W, Q, X, Y, B1, B2, Z1, Z2, and R1-R7 are as define... | 10/26/2010 |
| 7816346 | Analogs of ansamycin and pharmaceutical compositions thereof Analogs of geldanamycin (an ansamycin), pharmaceutical formulations comprising such analogs, and methods of use (e.g., treating tumors). ... | 10/19/2010 |
| 7812013 | Macrocyclic heterocyclic aspartyl protease inhibitors Disclosed are compounds of the formula I or a stereoisomer, tautomer, or pharmaceutically acceptable salt, solvate or ester thereof, wherein U, W, X, L, Y, M, Z, c, d, e, f, g, h, s, t, R1, R2, R7... | 10/12/2010 |
| 7807661 | Silver ion releasing articles and methods of manufacture A biologically-active article includes a substrate having a substrate surface and a silver releasing chromonic material disposed adjacent to the substrate surface. The silver releasing chromonic material includes a chromonic compound and a silver ion source. Methods... | 10/05/2010 |
| 7807662 | Platinum IV complex inhibitor The invention disclosed herein provides methods for diagnosing and treating diseases and/or conditions associated with dysregulated Stat3-mediated activity. ... | 10/05/2010 |
| 7803790 | Compounds for modulating TRPV3 function The present application relates to compounds and methods for treating pain and other conditions related to TRPV3. ... | 09/28/2010 |
| 7799772 | Pyrido-and pyrimidopyrimidine derivatives as anti-profilerative agents The present invention concerns the compounds of formula wherein a1-a2=a3-a4 represents a divalent radical selected from N—CH═CH—CH, N—CH═N—CH or CH—CH... | 09/21/2010 |
| 7795242 | Methods and compositions for immunomodulation Novel antigens are provided herein. The antigens are associated with recognition of CD1 molecules by T cells. These antigens can be used as antigens, adjuvants or as immunomodulatory agents in a variety of therapeutic and prophylactic applications. ... | 09/14/2010 |
| 7781423 | Compounds to promote regeneration of bone marrow Embodiments of the present invention include the use of heterocyclic trialkyl ammonium-containing compounds to promote regeneration of bone marrow from endogenous or exogenous stem/progenitor cells and to normalize blood cell and platelet counts. ... | 08/24/2010 |
| 7781422 | Antiviral indoles Compounds of the formula (I): wherein A, B, D, M, Ar, W, X, Y, Z and R1 are as defined herein, are useful in the prevention and treatment of hepatitis C infections. The compounds, their preparation, pharmaceutica... | 08/24/2010 |
| 7776847 | Benzisothiazoles useful for treating or preventing HCV infection The present invention relates to benzisothiazoles and pharmaceutical compositions thereof that inhibit replication and/or proliferation of HCV virus. The present invention also relates to the use of the benzisothiazoles and pharmaceutical compositions comprising the... | 08/17/2010 |
| 7776848 | Spirocyclic cyclohexane compounds Spirocyclic cyclohexane compounds, methods for their preparation, pharmaceutical compositions containing such compounds, and the use of such compounds to treat and/or inhibit specific undesirable conditions in a patient. ... | 08/17/2010 |
| 7776849 | Benzenoid ansamycin derivative The present invention provides a benzenoid ansamycin derivative represented by Formula (I) (wherein R1 and R2 each represent a hydrogen atom or are combined together to form a bond, R... | 08/17/2010 |
| 7772222 | Polar hydrophilic prodrugs of amphetamine and other stimulants and processes for making and using the same Disclosed are polar, hydrophilic stimulant prodrug compositions comprising at least one stimulant chemically attached to a polar hydrophilic ligand, a salt thereof, a derivative thereof, or a combination thereof. Methods of making and using the same are also disclos... | 08/10/2010 |
| 7772221 | Diaminopropane derived macrocycles as inhibitors of β amyloid production There is provided a series of macrocyclic diaminopropanes of Formula (I) or a stereoisomer; or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, m, n, W, X, Y, Z and L as defin... | 08/10/2010 |
| 7767660 | Antiviral indoles Compounds of the formula (I): wherein A, B, D, M, Ar, W, X, Y, Z and R1 are as defined herein, are useful in the prevention and treatment of hepatitis C infections. The compounds, their preparation, pharmaceutica... | 08/03/2010 |
