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| Number | Title | Issue Date |
| 8163725 | Gel compositions and methods of use Improved topical gel compositions for the treatment of skin disorders are described. The gel compositions contain carbomer and methylparaben, and are substantially free of methylparaben crystalline particles after an extended period of storage. ... | 04/24/2012 |
| 8053427 | Brimonidine gel composition Improved topical gel compositions, such as those containing brimonidine, for the treatment of skin disorders are described. The gel compositions contain carbomer and methylparaben, and are substantially free of methylparaben crystalline particles after an extended p... | 11/08/2011 |
| 7566705 | Combination of formoterol and mometasone furoate for asthma A medicament containing, separately or together, (A) formoterol or a pharmaceutically acceptable salt thereof or a solvate of formoterol or a solvate of the salt and (B) mometasone furoate, for simultaneous, sequential or separate administration in the treatment of ... | 07/28/2009 |
| 7553829 | Treatment of chronic fatigue syndrome and fibromyalgia syndrome Chronic fatigue syndrome (CFS) and fibromyalgia syndrome (FMS) can be treated by the administration of Δ5-androstene-3β-ol-7,17 dione and metabolizable precursors thereof. ... | 06/30/2009 |
| 7442386 | Synthesis and use of reagents for improved DNA lipofection and/or slow release prodrug and drug therapies The invention relates to compositions and methods for a one-step synthetic technique for making cationic steroid or cationic drug molecules for use as delivery vehicles. The invention further relates to methods for using cationic steroid molecules in lipofection or ... | 10/28/2008 |
| 7378405 | Stabilized steroid composition and method for its preparation Stabilized 17-substituted hydrocortisone containing compositions and methods of manufacture. Isomerization of the hydrocortisone component of topical steroid compositions is markedly reduced by introducing an omega-6. acid in the form of linoleic acid into the skin ... | 05/27/2008 |
| 7345035 | Treatment of osteoporosis and autoimmune disease with astrogorgiadiol The invention provides methods of downregulating mRNA encoding osteopontin comprising administering to a cell or mammal an amount of astrogorgiadiol effective to downregulate production of mRNA encoding osteopontin. The invention also provides methods of treating os... | 03/18/2008 |
| 7335650 | Composition There is provided a pharmaceutical composition comprising (i) a compound of the formula wherein: X is a hydrocarbyl ring having at least 4 atoms in the ring; K is a hydrocarbyl group; Rs is a sulphamate group; (ii) optional... | 02/26/2008 |
| 7192941 | Estradiol metabolites for the treatment of pulmonary hypertension Methods are provided for the treatment of pulmonary hypertension and other conditions associated therewith. In particular, the methods include treatment of pulmonary hypertension with estradiol metabolite or estradiol metabolite associated with biodegradable micropa... | 03/20/2007 |
| 7163934 | Methods for treating delirium glucocorticoid receptor-specific antagonists This invention generally pertains to the field of psychiatry. In particular, this invention pertains to the discovery that agents which inhibit the binding of cortisol to its receptors can be used in methods for treating delirium. Mifepristone, a potent specific glu... | 01/16/2007 |
| 7148213 | Antigestagenically active steroids with a fluorinated 17α-alkyl chain This invention describes the new 17α-fluoroalkyl steroids of general formula I as well as their physiologically compatible salts with bases. The new compounds have an extraordinary strong antigestagenic ... | 12/12/2006 |
| 7138427 | 5-β-sapogenin and pseudosapogenin derivatives and their use in the treatment of dementia The invention discloses the use of sapogenin derivatives in the treatment of cognitive disfunction and similar conditions. Methods of treatment and pharmaceutical compositions are also disclosed ... | 11/21/2006 |
| 7071328 | Method for the preparation of 21-hydroxy-6,19-oxidoprogesterone (21 oh-6op) The present invention relates to a novel method for preparing 21-hydroxy-6,19-oxidopro-gesterone (21OH-6OP) and/or its 21-acetate, 21-propionate, 21-hemisuccinate, 21-phosphate, 21-oleate derivatives. 21OH-6OP and its ester derivatives are antiglucocorticoids for th... | 07/04/2006 |
| 7067502 | Combinations of formoterol and mometasone furoate for asthma A medicament containing, separately or together, (A) formoterol or a pharmaceutically acceptable salt thereof or a solvate of formoterol or a solvate of the salt and (B) mometasone furoate, for simultaneous, sequential or separate administration in the treatment of ... | 06/27/2006 |
| 7053074 | Prevention of ovarian cancer by administration of a Vitamin D compound The present invention relates to methods for preventing the development of epithelial ovarian cancer by administering a Vitamin D compound in an amount capable of increasing apoptosis in non-neoplastic ovarian epithelial cells of the female subject. ... | 05/30/2006 |
| 6995149 | Contraceptive process and kit for female mammals, comprising a combination of gestagen and oestrogen The present invention relates to a female mammal contraceptive process consisting of the sequential administration for at least 28 days of (a) a gestagen in an ovulation-preventing dose for at least 28 days in combination with (b) a natural oestrogen for 5 to 10 day... | 02/07/2006 |
| 6916365 | Solventborne and activated solventborne paint packs, and waterborne coating compositions containing them A pigmented solventborne paint pack which can be made into a waterborne coating composition is provided, which comprises: i) a solution in an organic solvent of polymer having functional groups and hydrophilic groups; and ii) a waterborne pigment dispersion comprisi... | 07/12/2005 |
| 6844320 | Treatment of preeclampsia, toxemia and preterm labor with combination of progestational agent and a nitric oxide synthase substrate and/or donor Preeclampsia and preterm labor in a pregnant female mammal are treated by administering thereto a combination of a progestin and a nitric oxide synthase substrate, a nitric oxide donor or both, optionally in further combination with one or more of a cyclooxygenase i... | 01/18/2005 |
| 6835724 | Corticoid 17,21-dicarboxylic esters and corticosteroid 17-carboxylic ester 21-carbonic esters, processes for their preparation and pharmaceuticals containing these compounds Corticoid 17,21-dicarboxylic esters and corticosteroid 17-carboxylic ester 21-carbonic esters, processes for their preparation and pharmaceuticals containing these compounds Corticoid 17,21-dicarboxylic esters and corticoid 17-carboxylic ester 21-carbonic est... | 12/28/2004 |
| 6806263 | Antigestagenically active steroids with a fluorinated 17-alpha-alkyl chain 17α-fluoroalkyl steroids of formula I as well as their physiologically compatible salts with acids and for —CO2R9 radicals with R9 meaning hydrogen, as well their physiologically com... | 10/19/2004 |
| 6803060 | Composition to boost libido There is provided a natural composition for boosting the libido of an individual, the composition including an effective amount of an aphrodisiac and a compound to increase blood flow to the pelvic area in a pharmaceutically acceptable carrier. A natural composition... | 10/12/2004 |
| 6762175 | Fatty acid derivatives The properties of biologically active compounds, for example drugs and agrochemicals, which contain in their molecular structure one or more functional groups selected from alcohol, ether, phenyl, amino, amido, thiol, carboxylic acid and carboxylic acid ester groups... | 07/13/2004 |
| 6656970 | Method and compositions for solubilization of pentacyclic triterpenes The present invention provides compositions and methods for the solubilization of poorly soluble drugs such as triterpenes like betulinic acid and/its derivatives in pharmaceutically acceptable liquid vehicles that avoid use of potentially toxic solvents ... | 12/02/2003 |
| 6617319 | Methods of use for 2-deoxy ecdysterone The invention provides a process for the isolation of 2-deoxy ecdysterone from Zoanthus sp process comprising the steps (a) preparing crude methanol extract of Zoanthus sp., (b) subjecting the crude methanol extract to fractionation using petroleum ether,... | 09/09/2003 |
| 6610674 | Method of treating inflammatory conditions with progesterone analogs The present invention provides methods for treating inflammatory conditions, including but not limited to, inflammatory bowel disease (ulcerative colitis, Crohn's disease, and proctitis), other noninfectious, inflammatory conditions of the GI tract (micro... | 08/26/2003 |
| 6579862 | Method of treating hyperlipidemic and hyperglycemic conditions in mammals using pregnadienols and pregnadienones The invention provides a method of using pregnadienones and pregnadienols represented by the structural formula (I): ##STR1## containing at least one olefinic bond in or on their D-ring for the treatment of hyperlipidemic and hyperglycemic conditions in m... | 06/17/2003 |
| 6514516 | Formulations and methods for providing prolonged local anesthesia A formulation and methods for inducing sustained regional local anesthesia in a patient comprising a substrate comprising a local anesthetic and an effective amount of a biocompatible, biodegradable, controlled release material prolonging the release of t... | 02/04/2003 |
| 6511970 | Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium The present invention relates to compositions and methods for preventing the development of epithelial ovarian cancer by administering compounds in an amount capable of increasing TGF-ଲ expression in the ovarian epithelium. HRT and OCP regimens comp... | 01/28/2003 |
| 6479475 | Oral contraceptive This invention provides a method of contraception which comprises administering to a female of child bearing age for 23-25 consecutive days, a first phase combination of a progestin at a daily dosage of 40-500 μg trimegestone, 250 μg-4 mg dienogest, or 250 Î... | 11/12/2002 |
| 6468994 | Budesonide particles and pharmaceutical compositions containing them The invention provides finely divided, substantially crystalline particles of budesonide characterized in that they are substantially smooth and having a BET value of from 1 to 4.5 m2/g, a process for their preparation, a pharmaceutical composition compri... | 10/22/2002 |
| 6395746 | Methods of treating ophthalmic, otic and nasal infections and attendant inflammation Methods of treating or preventing ophthalmic, otic, and nasal infections and attendant inflammation are described. The methods utilize ophthalmic, otic, and nasal compositions containing a new class of antibiotics (e.g. trovafloxacin). The compositions al... | 05/28/2002 |
| 6369115 | Stabilized powder formulations A dry powder formulation for treatment of pulmonary conditions, via inhalation, includes an effective amount of formoterol or a salt or solvate thereof, in a dry powder form, an effective amount of fluticasone, in a dry powder form, and an excipient. A me... | 04/09/2002 |
| 6365580 | Process for the production of difluoromethane The present invention provides a vapor phase process for the production of difluoromethane, HFC-32. The process of this invention provides for the preparation of HFC-32 by a process that exhibits both good product yield and selectivity.... | 04/02/2002 |
| 6350739 | Methods of prevention and treatment of ischemic damage The present invention in various embodiments provides methods of treating stroke and conferring protection on a population of cells associated with ischemia in a subject following an ischemic event, comprising: (a) providing an estrogen compound; and (b) ... | 02/26/2002 |
| 6346523 | Budesonide particles and pharmaceutical compositions containing them The invention provides finely divided, substantially crystalline particles of budesonide characterized in that they are substantially smooth and having a BET value from 1 to 4.5 m2 /g, process for their preparation, a pharmaceutical composition... | 02/12/2002 |
| 6339078 | Methods of prevention and treatment of ischemic damage The present invention provides methods of conferring protection on a population of cells associated with ischemia in a subject following an ischemic event, comprising: (a) providing an estrogen compound; and (b) administering the effective amount of the c... | 01/15/2002 |
| 6329380 | SRC kinase inhibitor compounds Pyrimidine compounds (Formula I), or their pharmaceutically acceptable salts, hydrates, solvates, crystal forms and individual diastereomers, and pharmaceutical compositions including the same, which are inhibitors of tyrosine kinase enzymes, and as such ... | 12/11/2001 |
| 6326365 | Methods of prevention and treatment of ischemic damage The present invention provides methods of conferring protection on a population of cells associated with ischemia in a subject following an ischemic event, comprising: (a) providing an estrogen compound; and (b) administering the effective amount of the c... | 12/04/2001 |
| 6319914 | Cytoprotective effect of polycyclic phenolic compounds The invention comprises methods for conferring a cytoprotective effect on a population of cells, such as providing a polycyclic phenolic compound in a physiologically acceptable formulation, and administering the formulation in an effective dose to the po... | 11/20/2001 |
| 6316432 | Antigestagenically active steroids with a flourinated 17 -alkyl chain This invention describes the new 17-fluoroalkyl steroids of general formula I ##STR1## as well as their physiologically compatible salts with acids, and for --CO2 R9 radicals with R9 meaning hydrogen as well as thei... | 11/13/2001 |
