Did You Know...
...Chester Carlson was a patent agent who tired of having to make multiple copies of patent applications using the only duplication method available at the time: carbon paper. In 1959 he came up with a new copying system and took it to IBM for evaluation. The "experts" at IBM determined potential sales to be only 5,000 units because people wouldn't want to use a bulky machine when they had carbon paper. Carlson's invention was the xerography process, the company founded on the system is Xerox.
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| Number | Title | Issue Date |
| 4215112 | Tripeptides and methods There are disclosed new biological active polypeptides: wherein A is deamino-LYS or LYS; X is a suitable neutral aliphatic amino acid residue; e.g., one selected from the group consisting of SER, ALA, 2-Me-ALA, GLY, LEU, THR, D-SER, D-ALA, D-THR, allo-THR, D-L... | 07/29/1980 |
| 4215111 | Peptides having ubiquitin-like activity Peptides of the following formula: wherein A is a member selected from the group consisting of deamino-GLN, GLN, and (SAR)n -GLN; n is an integer from 1 to 4; and B is a member selected from the group consisting of LYS-OH, LYS-NH2, decarb... | 07/29/1980 |
| 4199568 | Tetrapeptide amides Tetrapeptide amides of the formula ##STR1## wherein R1, R2, R3, A and B represent certain specified substituent groups and where n is 2-5, p is 1-5 and r is 1 or 2. The compounds exhibit pharmacological activity when ... | 04/22/1980 |
| 4187295 | Organic compounds The invention provides polypeptides useful, for example, as soporifics, a process for the preparation thereof and compositions containing these compounds.... | 02/05/1980 |
| 4186198 | Chemical compounds The invention relates to L-pyroglutamyl-L-seryl-glycyl-glycine amide which possesses the ability to increase serum testosterone levels and is thus of interest in promoting anabolism and other hormonal effects associated with testosterone. Process for the ... | 01/29/1980 |
| 4183909 | Phenylglycine-containing new peptides with gastrine effects and a process for the preparation thereof The invention relates to novel peptides of formula (I), wherein A is tert.-butoxycarbonyl-aminooxy-acyl, benzyloxycarbonyl-aminooxy-acyl, (aminooxy)-acyl or E-aminooxy-acyl, wherein E is benzoyl or straight-chained or branched C1-5 aliphatic acyl, a... | 01/15/1980 |
| 4181717 | Ovulation enhancing peptides Polypeptides containing at least four amino acids are useful to enhance ovulation in mammals.... | 01/01/1980 |
| 4178371 | Tetrapeptide derivatives Tetrapeptide amides of the formula ##STR1## wherein R1, R8, Rx, B and D represent certain specified substituent groups. The compounds exhibit pharmacological activity when tested in vitro in the transmurally stimulate... | 12/11/1979 |
| 4172130 | -AMINOACYL CONTAINING NEW PEPTIDES WITH GASTRIN EFFECTS AND A PROCESS FOR THE PREPARATION THEREOF Peptides of the formula: wherein A is tert.-butoxycarbonyl-aminooxy-acyl, benzyloxycarbonyl-aminooxy-acyl, (aminooxy)-acyl, or E-aminooxy-acyl, wherein E is benzoyl or straight-chain or branched C1-5 aliphatic acyl, B is methionyl, leucyl, norl... | 10/23/1979 |
| 4167563 | TRH Solution An injectable solution containing a trihydric to hexahydric sugar alcohol together with L-pyroglutamyl-L-histidyl-L-prolinamide or a physiologically acceptable salt thereof shows significantly reduced pain when administered to a host, especially subcutane... | 09/11/1979 |
| 4164571 | Medicament which antagonizes the action of gastrin and related polypeptides The present invention relates to a method of treating diseases and particularly gastroduodenal ulcers linked to an hypersecretion of gastrin, and to polypeptide amide derivatives which can be used in this method as therapeutic agents and more specifically... | 08/14/1979 |
| 4161522 | Method for blocking allergic responses A group of relatively low molecular weight polypeptides having from 3 to 10 amino acids block the allergic response. These "blocking" polypeptides have amino acid sequences corresponding to amino acid sequences appearing in the 2nd, 3rd and 4th domains of... | 07/17/1979 |
| 4150120 | Ophthalmic Eye diseases in mammals such as progressive cataract or conjunctivitis are effectively treated by administering to the mammals a thyroid stimulating hormone releasing hormone. The treatment effect is enhanced by the concomitant administration of the said ... | 04/17/1979 |
| 4146614 | Threonyl-valyline leucine containing peptides and pharmaceutical compositions Polypeptides, omega-N-acylated and/or hydrocarbon-containing esters or amides of polypeptides are useful in the treatment of schizophrenia. The polypeptide-containing materials have a characteristic T-V-L structure, i.e., ##STR1## The preferred ... | 03/27/1979 |
| 4127534 | Novel tripeptides, intermediates therefor and pharmaceutical compositions and methods employing said tripeptides Novel tripeptides having the following amino acid sequence wherein: X is a chiral residue of a D-amino acid selected from the group consisting of D-alanine, D-leucine, D-isoleucine, D-valine, D-phenylalanine, D-tyrosine, D-tryptophan, D-serine, D-threonine, ... | 11/28/1978 |
| 4125605 | Method of employing oral TRH Improved methods of employing TRH to enhance lactation and to prolong postpartum infertility are disclosed. The methods may be employed with women following full term delivery, as well as in cases of premature birth. In addition, a method for the use of T... | 11/14/1978 |
| 4104371 | Psychopharmacologically active peptides and peptide-derivatives, and the use thereof Biologically active novel peptides and peptide-derivatives of the general formula: ##STR1## where A represents H-(L or D)Met, H-(L or D)Met(.fwdarw.O), H-(L or D)Met(.fwdarw.O2) desamino-Met, desamino-Met(.fwdarw.O), desamino-Met(.fwdarw.O... | 08/01/1978 |
| 4095000 | Protein-saving foodstuff and fodder additive Foodstuff and fodder additives are made by linking essential aminoacids to carbohydrates or other assimilable polyhydroxy compounds in such a way that the aminoacid is liberated in the digestive tract.... | 06/13/1978 |
| 4088755 | Medicament for remedying schizophrenia The concomitant administration of L-pyroglutamyl-L-histidyl-L-prolinamide or its physiologically acceptable salt with one or more neuroleptics to patients suffering from schizophrenia can attain remarkable improvement of the overall disease picture of the... | 05/09/1978 |
| 4081533 | Method of reducing mammalian fertility and drugs therefor The pre-ovulatory surge of luteinizing hormone from the pituitary gland is selectively suppressed or eliminated by introducing nonapeptide, 8-arginine vasotocin, or the tripeptide, propyl-arginyl-glycinamide, into the subject. Analogs and related peptides... | 03/28/1978 |
| 4073890 | Novel polypeptides Novel polypeptides of the formula R1 --Arg--R2 --Phe--Phe--R3 wherein R1 is hydrogen, or a basic or neutral amino acid residue, R2 is a neutral amino acid residue and R3 is NH2, Tyr--... | 02/14/1978 |
| 4066749 | Tetrapeptide analog of TRH A novel tetrapeptide L-2-ketopiperidine-6-carbonyl-L-histidyl-L-thiazolidine-4-carbonyl-ଲ- alanin-amide, (L-Kpc-L-His-L-Tca-ଲ-ala-NH2), is a stimulant of the central nervous system. It is preparable by standard peptide synthetic ... | 01/03/1978 |
| 4064235 | Dopamine derivative compounds, preparation thereof and medicine containing same A novel dopamine derivative compound having the following general formula and pharmacologically acceptable acid addition salt thereof: ##STR1## wherein X stands for a di- or tri-peptide residue derived from alanine, glycine, glutamine, isoleucine, ly... | 12/20/1977 |
| 4064236 | Peptide carbazates and pharmaceutical composition Certain novel peptide carbazates, their preparation, pharmaceutical compositions and novel methods of treating pancreatitis.... | 12/20/1977 |
| 4060603 | Histidine derivatives Compounds of the formula ##STR1## wherein R, R1, R2, R3 and R4 represent certain specified substituent groups. The compounds exhibit activity in the reserpine induced hypothermia test.... | 11/29/1977 |
| 4059692 | Treating impaired consciousness with glutamyl-L-histidyl-L-prolinamide The impaired consciousness due to functional or organic damage of the brain in human patients can be significantly improved and restored, without any undesirable side-effect, by administering to the patients L-pyroglutamyl-L-histidyl-L-prolinamide or its ... | 11/22/1977 |
| 4053588 | Pharmaceutical preparations having psychotropic activity and process for their manufacture Pharmaceutical preparations containing an L-pyroglutamic acid amide, processes for their preparation and methods of treating psychotic diseases with them.... | 10/11/1977 |
| 4048305 | Tripeptides, their esters and amides, and anti-ulcera activity thereof This invention relates to aseries of tripeptides of the general formula: ##STR1## wherein R = -- H, COCH3, alkyl R1 = --oh, --nh2, --nh alkyl (C1 -C5) --O alkyl (C1 -C5) resultin... | 09/13/1977 |
| 4029772 | Peptide carbazates Certain novel peptide carbazates, their preparation, pharmaceutical compositions and novel methods of treating pancreatitis.... | 06/14/1977 |
| 4018912 | Tripeptide derivatives with central nervous system activity and preparation thereof The tripeptide derivatives of formula 1 in which R1 is hydrogen, lower alkyl or NR4 R5 wherein R4 and R5 each are lower alkyl, R2 is hydrogen or lower alkyl, R3 is amino, lower alkyla... | 04/19/1977 |
| 4016259 | Contraceptive polypeptides Polypeptides containing at least four amino acids are useful as mammalian contraceptives.... | 04/05/1977 |
| 3932623 | Method of treating schizophrenia An improved method of treating schizophrenia and allied conditions such as childhood schizophrenia and autism using thyrotropin releasing hormone, L-pyroglutamyl-L-histidyl-L-proline amide, or its congeners as a treating agent.... | 01/13/1976 |
