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| Number | Title | Issue Date |
| 8148353 | Polymorphs of fluticasone furoate and process for preparation thereof Provided are polymorphs of fluticasone furoate and processes for preparation thereof. ... | 04/03/2012 |
| 7939516 | Topical skin care composition A cream base for the topical application of skin care therapeutics and a process for making the cream base. In one embodiment, the therapeutic is tretinoin, hydroquinone and fluocinolone acetonide for the treatment of hyperpigmented skin conditions, such as melasma.... | 05/10/2011 |
| 7915243 | Topical skin care composition A cream base for the topical application of skin care therapeutics and a process for making the cream base. In one embodiment, the therapeutic is tretinoin, hydroquinone and fluocinolone acetonide for the treatment of hyperpigmented skin conditions, such as melasma.... | 03/29/2011 |
| 7875598 | Compositions useful for the treatment of microbial infections The present invention is based on the discovery that certain chemical compounds isolated from Chinese medicinal herbs are useful as anti-microbial agents, e.g., anti-bacterial agents, anti-fungal agents, and the like. In particular, the present invention provides co... | 01/25/2011 |
| 7683048 | Polymorphis of a known thiophenecarboxylic acid dodecahydrocyclopenta (a) phenanthrenyl ester Polymorphic crystal forms of 3-methylthiophene-2-carboxylic acid (6S,9R,10S,11S,13S,16R, 17R)-9-chloro-6-fluoro-11-hydroxy-17-methoxycarbonyl-10,13,16-trimethyl-3-oxo-6,7,8,9,10, 11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl ester. The crystal f... | 03/23/2010 |
| 7629335 | Anti-inflammatory androstane derivative According to one aspect of the invention, there is provided a compound of formula (I) and solvates thereof. There are also provided compositions containing the compound, processes for preparing it, and its use in therapy. | 12/08/2009 |
| 7615546 | Topical delivery system for phytosterols This invention relates to certain sugar esters of phytosterols of formula (I). These esters are useful for topical application, and for the treatment of skin condition, including age spots, acne, loss of cellular antioxidants, collagen loss, loss of skin pliability,... | 11/10/2009 |
| 7592329 | Crystalline complexes of fluticasone-2-furoate There is provided a crystalline complex comprising a compound of formula (I) in which the crystal lattice is stabilized by the presence of a guest molecule, characterized in that the crystalline complex is of space group P2... | 09/22/2009 |
| 7544674 | Topical skin care composition A cream base for the topical application of skin care therapeutics and a process for making the cream base. In one embodiment, the therapeutic is tretinoin, hydroquinone and fluocinolone acetonide for the treatment of hyperpigmented skin conditions, such as melasma.... | 06/09/2009 |
| 7541350 | Formulation containing anti-inflammatory androstane derivative There is provided a pharmaceutical formulation comprising an aqueous suspension of particulate compound of formula (I) or a solvate thereof. ... | 06/02/2009 |
| 7531528 | Formulation containing anti-inflammatory androstane derivatives There is provided according to the invention a pharmaceutical formulation comprising an aqueous carrier liquid having dissolved therein (a) an ester of fluticasone or a solvate thereof as medicament and (b) a solubilizing agent for assisting the solubilization of th... | 05/12/2009 |
| 7498321 | 17β-carbothioate 17α-arylcarbonyloxyloxy androstane derivative as anti-inflammatory agents There are provided according to the invention compounds of formula (I) wherein R1 represents C1-6 alkyl or C1-6 haloalkyl; R2 represents —C(═O)-aryl or —C(═O)-heteroaryl; R3 represents hydrogen, methyl (... | 03/03/2009 |
| 7405206 | Anti-inflammatory androstane derivatives There are provided compounds of formula (I) wherein R1 represents O, S or NH; R2 represents —C(═O)-aryl or —C(═O)-heteroaryl; R3 represents hyd... | 07/29/2008 |
| 7365085 | Compounds and methods Disclosed is a compound having the formula: pharmaceutically acceptable salts or solvates thereof and pharmaceutical compositions containing the same, wherein the structural variables are as defined... | 04/29/2008 |
| 7361645 | Androgenic 7-substituted 11-halogen steroids The invention relates to 11β-halogen steroids with general formula (I), whereby R11 is halogen, X—Y-Z represents a group with one of the two structures CH═C—C or CH2—C═C and the other radicals have the meaning that is indicated in th... | 04/22/2008 |
| 7335349 | Fish attractants The present invention provides a fish attracting composition. Previously fish sex hormones were considered only to have a role in sexual reproduction, however the present invention shows that these hormones can be used to induce feeding behaviour in fish. In particu... | 02/26/2008 |
| 7323494 | Compounds and methods Disclosed is a compound of having the formula: pharmaceutically acceptable salts or solvates thereof and pharmaceutical compositions containing the same, wherein the structural variables ... | 01/29/2008 |
| 7312207 | Topical steroid cream formulations Disclosed is a novel mometasone furoate cream formulation for topical administration in a oleaginous base containing propylene glycol. This cream is a cosmetically elegant preparation of mometasone that is both stable and bioeffective. ... | 12/25/2007 |
| 7288533 | Topical application for treating toenail fungus A topical applications is used to treat and prevent the spread of nail infections or onychomycosis caused by bacteria, fungi and other pathogens. The topical application has a composition that comprises, as an active ingredient, at least one species selected from th... | 10/30/2007 |
| 7265099 | Use of chemical chelators as reversal agents for drug-induced neuromuscular block The invention relates to the use of chemical chelators for the preparation of a medicament for the reversal of drug-induced neuromuscular block, to a kit for providing neuromuscular block and its reversal, and to cyclophane derivatives having general formula (A) whe... | 09/04/2007 |
| 7250408 | Glucocorticoid receptor antagonists for prophylaxis and therapy of glucocorticoid-mediated hypogonadism, of sexual dysfunction and/or infertility The novel glucocorticoid receptor antagonists are 11β-substituted steroid compounds of formula (I): wherein R1 denotes a methyl group, a methoxy group, or an ethoxy group; wherein R2 denote... | 07/31/2007 |
| 7247748 | Amide compounds and methods of using the same Disclosed is a compound having the formula (I) pharmaceutically acceptable salts or solvates thereof and pharmaceutical compositions containing the same, wherein the structural variables are as defined herein. The compounds, salts and solvates of this invention are ... | 07/24/2007 |
| 7192963 | Pyrrolo[2,3-d]pyrimidine compounds A compound of the formula wherein R1, R2 and R3 are as defined above, useful as inhibitors of protein kinases, such as the enzyme Janus Kinase 3. ... | 03/20/2007 |
| 7166611 | Pharmaceutical compositions having appetite suppressant activity A pharmaceutical composition contains an extract obtainable from a plant of the genus Trichocaulon or Hoodia containing an appetite suppressant agent having the formula (1). A process for obtaining the extract and a process for synthesizing compound (1... | 01/23/2007 |
| 7153930 | Peptide transport The present invention relates to improving and/or increasing the bioavailability of a biologically active substance, such as a peptide. In particular, the present invention relates to the conjugation of the biologically active substance to a bile acid. The conjugate... | 12/26/2006 |
| 7139055 | Liquid crystal display device having liquid crystal domains with radially-inclined orientation The liquid crystal display device of this invention includes a vertical alignment type liquid crystal layer between a first substrate and a second substrate. A picture element region is defined by a first electrode provided on the surface of the first substrate faci... | 11/21/2006 |
| 7138427 | 5-β-sapogenin and pseudosapogenin derivatives and their use in the treatment of dementia The invention discloses the use of sapogenin derivatives in the treatment of cognitive disfunction and similar conditions. Methods of treatment and pharmaceutical compositions are also disclosed ... | 11/21/2006 |
| 7121837 | Connector A new connector that is reduced in size and has a higher density of contacts implemented therein is provided. This connector has a contact module arranged on a connector main body. The contact module is formed into a sheet structure, and a plurality of contacts are ... | 10/17/2006 |
| 7112580 | 3-nitrogen-6, 7-dioxygen steroids and uses related thereto A compound of the formula: and pharmaceutically acceptable salts, solvates, stereoisomers and prodrugs thereof, in isolation or in mixture, wherein R groups are as defined by the present specification. The compou... | 09/26/2006 |
| 7108867 | Process for preparing particles A process for preparing particles of a substance, such as a protein or polypeptide, comprising: (a) preparing a first liquid comprising water, the substance and a modulator, wherein the modulator has a solubility in water which decreases with increasing temperature;... | 09/19/2006 |
| 7101866 | Anti-inflammatory androstane derivative According to one aspect of the invention, there is provided a compound of formula (I) and solvates thereof. There are also provided compositions containing the compound, processes for preparing it, and its use in thera... | 09/05/2006 |
| 7087590 | 19-norbufalin derivatives, their preparation and pharmaceutical compositions containing them A 19-norbufalin derivative compound of formula (I): wherein the R groups are as defined by the present specification. The compounds are Na+K−-ATPase inhibitors and can be used in the treat... | 08/08/2006 |
| 7078057 | Process for producing nanometer particles by fluid bed spray-drying Nanometer particles of poorly water-soluble or substantially water-insoluble compound are produced by finely-spraying a non-aqueous solution of said compound into a heated and fluidized bed of carrier excipient. The resulting product consists of a free flowing mixtu... | 07/18/2006 |
| 7071328 | Method for the preparation of 21-hydroxy-6,19-oxidoprogesterone (21 oh-6op) The present invention relates to a novel method for preparing 21-hydroxy-6,19-oxidopro-gesterone (21OH-6OP) and/or its 21-acetate, 21-propionate, 21-hemisuccinate, 21-phosphate, 21-oleate derivatives. 21OH-6OP and its ester derivatives are antiglucocorticoids for th... | 07/04/2006 |
| 7067682 | 6,7-Oxygenated steroids and uses related thereto Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of positions 6 and 7. Thus, certain steroids have oxygen substitution at C6 an... | 06/27/2006 |
| 7053074 | Prevention of ovarian cancer by administration of a Vitamin D compound The present invention relates to methods for preventing the development of epithelial ovarian cancer by administering a Vitamin D compound in an amount capable of increasing apoptosis in non-neoplastic ovarian epithelial cells of the female subject. ... | 05/30/2006 |
| 7053076 | Bile-acid derived compounds for enhancing oral absorption and systemic bioavailability of drugs Disclosed are compounds that exhibit high transport across the intestinal wall of an animal. The compounds may optionally be linked to drugs that are poorly absorbed or poorly transported across the intestinal wall after oral administration to provide for enhanced t... | 05/30/2006 |
| 7049305 | Bile-acid conjugates providing for sustained systemic concentration of drugs This invention is directed to compounds that provide for sustained systemic concentrations of therapeutic or prophylactic agents following administration to animals. This invention is also directed to pharmaceutical compositions including and methods using such comp... | 05/23/2006 |
| 7048913 | Antifungal composition and method for human nails An antifungal composition for the treatment of fungal infections in, around and under human nails, the composition comprising an aqueous solution of a wetting agent such as alcohol and a source of fluoride ions sufficient to establish a pH ranging from about 2.8 to ... | 05/23/2006 |
| 7037548 | Soybean embryo fat/oil and process for producing soybean material with high embryo concentration The purpose of the present invention is to extract oil from the soybean material containing soybean germ as a main component, and to utilize it. The present invention relates to a method for producing a soybean material, comprising crudely crushing selected s... | 05/02/2006 |
