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Class 514/170 - Plural Compounds containing cyclopentanohydrophenanthrene ring systems


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein two or more bioactive compounds are
No. of patents: 340
Last issue date: 12/08/2009


1                  
NumberTitleIssue Date
7629334Mesoprogrestins (progesterone receptor modulations) as a component of compositions for hormone replacement therapy (HRT)
The use of mesoprogestins as pharmaceutical components for the manufacture of a medicament for hormone replacement therapy (HRT) and as components for the combined use together with an estrogen for the manufacture of a medicament for HRT as well as in respective HRT...
12/08/2009
7615545Oral contraceptives to prevent pregnancy and diminish premenstrual symptomatology
This invention relates to a method of preventing pregnancy and treating PMS including PMDD. More particularly, the invention relates to a method, which involves administering one of several combination oral contraceptive regimens in combination with an antidepressan...
11/10/2009
7601707Method for instantly relieving tissue inflammation
A method for treating an inflamed tissue includes locally applying a solution comprising a corticosteroid and an anesthetic agent to the inflamed tissue so that the solution directly contacts the inflamed tissue. The corticosteroid may be a 4 mg/ml dexamethasone sol...
10/13/2009
7589082Pharmaceutical formulation for contraception and hormone-replacement therapy
The present invention provides slow release estradiol-progesterone formulations that can be used in either contraception or hormone replacement therapies. The formulations comprise shaped particles of estradiol that is in a hemicrystalline form that exhibits especia...
09/15/2009
7572779Oral pharmaceutical products containing 17β-estradiol-3-lower alkanoate, method of administering the same and process of preparation
A pharmaceutical dosage unit for oral administration to a human female comprising a therapeutically effective amount of 17β-estradiol-3-lower alkanoate, most preferably 17β-estradiol-3-acetate, and a pharmaceutically acceptable carrier is disclosed. Also disclosed...
08/11/2009
7569560Extended cycle multiphasic oral contraceptive method
A multiphasic method of contraception provides for sequentially administering to a female of child bearing age: (a) a Phase I composition containing a progestogen and an estrogen for about 4 to about 7 days; (b) a Phase II composition containing a progestogen and an...
08/04/2009
7560448Enhancement of activity and/or duration of action of soft anti-inflammatory steroids for topical or other local application
Methods and compositions for enhancing the activity and/or duration of action of loteprednol etabonate and other soft anti-inflammatory steroids of the haloalkyl 17α-alkoxycarbonyloxy-11β-hydroxyandrost-4-en-3-one-17β-carboxylate type and the corresponding Δ
07/14/2009
7524833Method and apparatus for concentrating and stabilizing conjugated estrogens from mare urine
A method and apparatus for concentrating and stabilizing conjugated estrogens from pregnant mare urine on solid adsorbent supports to obtain a starting material for pharmaceuticals that contain a natural mixture of conjugated estrogen mixtures on cartridges in the v...
04/28/2009
7439235Method for obtaining estrogens from mare's urine
A method for obtaining an extract from a natural mixture of conjugated estrogens from the urine of pregnant mares (PMU) by solid-phase extraction on semipolar adsorption resins in which the resulting extract meets the pharmaceutical specifications for conjugated est...
10/21/2008
7348137Determination of testosterone by mass spectrometry
Provided are methods for determining the presence or amount of testosterone in a test sample, comprising ionizing all or a portion of the testosterone present in the sample to produce one or more testosterone ions that are detectable in a mass spectrometer. All or a...
03/25/2008
7335650Composition
There is provided a pharmaceutical composition comprising (i) a compound of the formula wherein: X is a hydrocarbyl ring having at least 4 atoms in the ring; K is a hydrocarbyl group; Rs is a sulphamate group; (ii) optional...
02/26/2008
7332525Method of treatment of prostate cancer and composition for treatment thereof
A method and composition for the treatment of prostate cancer comprises an effective amount of a nonsteroidal antiandrogen and an effective amount of a selective estrogen receptor modulator. The composition has fewer side effects such as breast tenderness and gyneco...
02/19/2008
7325358Weather protected deer and animal repellent container
A device for displaying an odorous animal repellent. The device comprises a housing having a chamber adapted for receiving the animal repellent. The device further comprises a retainer on the underside of the housing which allows permeation of the scent of the anima...
02/05/2008
73234557-aryl 1,5-dihydro-4,1-benzoxazepin-2(3)-one derivatives and their use as progesterone receptor modulators
This invention provides progesterone receptor modulators having the structure: wherein R1 to R7, X, and Q are as defined in the specification; or a pharmaceutically acceptable salt thereof. ...
01/29/2008
7320970Low dose estrogen interrupted hormone replacement therapy
A hormone replacement therapy, comprising a plurality of daily doses of a pharmaceutical preparation, the doses being administered continuously and consecutively in alternating phases of three daily doses, a relatively dominant estrogenic activity phase comprising t...
01/22/2008
7320969Oral contraceptives to prevent pregnancy and diminish premenstrual symptomatology
This invention relates to a method of preventing pregnancy and treating PMS including PMDD. More particularly, the invention relates to a method, which involves administering one of several combination oral contraceptive regimens in combination with an antidepressan...
01/22/2008
7304171Compounds and methods for cytoprotection
Compounds, compositions and methods for treating degenerative diseases and disorders are disclosed, the compounds having the following structure (I): including stereoisomers, prodrugs and pharmaceutically accepta...
12/04/2007
RE39861Methods of extended use oral contraception
A method of female contraception involves administering a combination of estrogen and progestin for 60-110 consecutive days in which the daily amounts of estrogen and progestin are equivalent to about 5-35 mcg of ethinyl estradiol and about 0.025 to 10 mg of norethi...
09/25/2007
7265101Appetite-suppressing compositions and methods
The invention relates to appetite-suppressing compositions obtained from botanical sources. More specifically, the invention relates to appetite-suppressing compositions comprising an extract product of an Asclepias plant, methods of making an appetite-suppre...
09/04/2007
7256184Treatment of aging disorders in humans
A method for the treatment and prophylaxis of conditions of aging in humans, such conditions of aging associated with a decreased presence of one or more cell-specific carbonic anhydrase enzymes. Such conditions include chronic neurodegenerative conditions including...
08/14/2007
7241755Epothilone derivatives
The present invention relates to compounds of the formula in which the variables G, W, Q, X, Y, B1, B2, Z1, Z2, and R1–R7 are as defined herein,...
07/10/2007
7223748Pharmaceutical formulations for dry powder inhalers in the form of hard-pellets
The invention provides a formulation to be administered as a dry powder for inhalation suitable for efficacious delivery of active ingredients into the low respiratory tract of patients suffering from a pulmonary disease such as asthma. In particular, the invention ...
05/29/2007
7220424Compositions and methods for enhancing corticosteroid delivery
The present invention comprises a composition, method of enhancing potency and method of delivering corticosteroids in a vehicle comprising at least two penetration enhancers, and solvents and emulsifiers. The propylene glycol and penetration enhancers are present i...
05/22/2007
7220733Separation of cresol from mares' urine
A method of separating cresol from mares' urine by pervaporation using pore-free polymeric silicone membranes in which starting urine solutions containing high-quality and -quantity conjugated estrogens with a reduced or substantially removed cresol content are prov...
05/22/2007
7217422Compositions and methods for enhancing corticosteroid delivery
The present invention comprises a composition, method of enhancing potency and method of delivering corticosteroids in a vehicle comprising at least two penetration enhancers, and solvents and emulsifiers. The propylene glycol and penetration enhancers are present i...
05/15/2007
7214672Preventives/remedies for inflammatory airway diseases
A preventive and/or therapeutic agent for inflammatory respiratory tract diseases containing, as an active ingredient, a steroid derivative represented by the following formula (1): (wherein R represents a hydrog...
05/08/2007
RE39592Extended release growth promoting two component composition
An extended release composition comprising a first composition comprising growth promoters and a second composition comprising growth promoters and a biodegradable polymer is described. A method of increasing weight gain in food animals utilizing the composition, a ...
04/24/2007
7198801Formulations for transdermal or transmucosal application
The present invention relates generally to formulations for transdermal or transmucosal administration of an active agent. The invention is a substantially malodorous-free and irritation free transdermal formulation which is substantially free of long chain fatty al...
04/03/2007
7196074Methods of making, using and pharmaceutical formulations comprising 7α, 11β-dimethyl-17β-hydroxyestra-4, 14-dien-3-one and 17 esters thereof
Methods of using 7α,11β-dimethyl-17β-hydroxyestra-4,14-dien-3-one (III) and 17 esters thereof for various hormonal therapies, oral and parenteral dosage forms comprising these actives, and processes for their ...
03/27/2007
7179799(3) and (6) substituted estrogenic compounds
Novel estrogenic compounds of Formula I are provided. wherein the bond represented by the wavy line may be a single or double bond such that when the wavy line is a single bond, R1 is selected from the...
02/20/2007
7125899Epothilone derivatives
The present invention relates to epothilone derivatives, having the following formula: in which the variables G, W, Q, X, Y, B1, B2, Z1, Z2, and R1–R7...
10/24/2006
7122578Method and composition for treating mammalian diseases and injuries which cause pain, erythema, swelling, crusting, ischemia scarring and excess white blood cell infiltration
A method for treating the disease state in mammals caused by mammalian cells involved in the inflammatory response is disclosed. Mammalian cells participating in the inflammatory response are contacted with an inflammatory suppressor selected from the group consisti...
10/17/2006
7115283Preparations for sustained release of nutraceuticals and methods of controllably releasing nutraceuticals
Preparations for the sustained release of a nutraceutical are described that include a solid matrix coated with a methylcellulose-containing coating. The solid matrix contains a polyphenol and the nutraceutical. Methods of controllably releasing a nutraceutical are ...
10/03/2006
7108867Process for preparing particles
A process for preparing particles of a substance, such as a protein or polypeptide, comprising: (a) preparing a first liquid comprising water, the substance and a modulator, wherein the modulator has a solubility in water which decreases with increasing temperature;...
09/19/2006
7081451Method and apparatus for concentrating and stabilizing conjugated estrogens from mare urine
A method and apparatus for concentrating and stabilizing conjugated estrogens from pregnant mare urine on solid adsorbent supports to obtain a starting material for pharmaceuticals that contain a natural mixture of conjugated estrogens as active ingredient. The appa...
07/25/2006
7081457Cyclothiocarbamate derivatives as progesterone receptor modulators
Methods of using compounds which are progesterone receptor agonists for contraception and the treatment of progesterone-related maladies alone or in combination with an estrogen receptor agonist or progesterone receptor antagonist are provided. These compounds have ...
07/25/2006
7078059Treatment of bone diseases
The invention provides a method for enhancing bone formation, inhibiting osteoclastic differentiation and/or activating osteoblastic differentiation whereby to manage, treat or achieve prophylaxis of bone disease which comprises administering to a human or animal su...
07/18/2006
7078394Low dose estrogen interrupted hormone replacement therapy
A hormone replacement therapy, comprising a plurality of daily doses of a pharmaceutical preparation, the doses being administered continuously and consecutively in alternating phases of three daily doses, a relatively dominant estrogenic activity phase comprising t...
07/18/2006
7074325Device for concentrating and stabilizing conjugated estrogens from mare urine
An apparatus for concentrating and stabilizing conjugated estrogens from pregnant mare urine on solid adsorbent supports to obtain a starting material for pharmaceuticals that contain a natural mixture of conjugated estrogens as active ingredient. The apparatus is s...
07/11/2006
7067505Di-steroidal prodrugs of estradiol
The present invention is a di-steroidal prodrug of estradiol having the following formula: ...
06/27/2006
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