...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8101592 | Hexahydro-cyclooctyl pyrazole cannabinoid modulators This invention is directed to a hexahydro-cyclooctyl pyrazole cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or... | 01/24/2012 |
| 8097604 | Combination of gestagen and insulin sensitizer for treating PCOS The present invention relates to a medicament which contains as the active ingredient combination at least one gestagen with a contraceptive action as the sole hormone component and at least one insulin sensitizer, which medicament is in particular suitable for prev... | 01/17/2012 |
| 8080539 | Method of treating human preeclampsia employing resibufagenin A method of treating preeclampsia including administering a therapeutically effective dose of resibufagenin to a patient having preeclampsia. Effecting the determination of the presence of preeclampsia may be by determining whether there has been a substantial eleva... | 12/20/2011 |
| 8076316 | Steroid compounds and formulations The invention provides methods to treating conditions such as prostate cancer, or for ameliorating one or more symptoms associated with prostate cancer, or for agents that modulate the biological activity of the androgen receptor. The invention also provides methods... | 12/13/2011 |
| 8071577 | Multi-phase contraceptive preparation based on a natural estrogen The multiphase preparation having higher contraceptive safety and reduced side effects is based on a combination of a natural oestrogen with dienogest or drospirenone. The multiphase preparation is characterized by a first phase consisting of 2 daily dose units of 3... | 12/06/2011 |
| 8071576 | Method of preventing or treating benign gynaecological disorders The present invention relates to a method of preventing or treating benign estrogen sensitive gynecological disorders in a female mammal, wherein the method comprises the administration to said female mammal of a combination of progestogen and androgen in an amount ... | 12/06/2011 |
| 8067400 | Androgen treatment in females A method of improving cumulative embryo score may comprise administering an androgen to a human female for at least about four consecutive months followed by harvesting and fertilizing oocytes and forming embryos. A method of increasing the quantity of fertilized oo... | 11/29/2011 |
| 8067399 | Method and apparatus for transdermal or transmucosal application of testosterone Methods, formulations, and devices for providing transdermal or transmucosal delivery of active agents to subjects in need thereof. The formulations and methods treat symptoms of hormonal disorders including hypogonadism, female sexual desire disorder, female menopa... | 11/29/2011 |
| 8063030 | Extended cycle multiphasic oral contraceptive method A multiphasic method of contraception comprising the steps of sequentially administering to a female of child bearing age a Phase I composition containing a progestogen in an amount equivalent to about 0.3 to about 1.5 mg norethindrone acetate and an estrogen in an ... | 11/22/2011 |
| 8048868 | Method of preventing preeclampsia A method of preventing preeclampsia including administering to a patient during an early stage of pregnancy a prophylactically-effective amount of resibufogenin. The administration of resibufogenin is periodically repeated. The method serves to prevent hypertension,... | 11/01/2011 |
| 8022052 | Inhibition of PPAR gamma expression by specific osteogenic oxysterols This invention relates to methods for using agents to inhibit peroxisome proliferator activated receptor expression. ... | 09/20/2011 |
| 7964586 | Method for obtaining a natural mixture of conjugated equine estrogens A method for obtaining an extract containing the natural mixture of conjugated equine estrogens in which a mixture of conjugated estrogens obtained by solid-phase extraction from pregnant mares' urine is depleted in phenolic urine contents and in non-conjugated lipo... | 06/21/2011 |
| 7935691 | Extended cycle multiphasic oral contraceptive kit A multiphasic contraceptive kit for use to practice a multiphasic method of contraception that provides for sequentially administering to a female of child bearing age: (a) a Phase I composition containing a progestogen and an estrogen for about 4 to about 7 days; (... | 05/03/2011 |
| 7910570 | Composition comprising a combination of an aromatase inhibitor, a progestin and an oestrogen and its use for the treatment of endometriosis The invention relates to a method of treating endometriosis using a combination of an aromatase inhibitor, a progestin and an oestrogen. The invention also relates to pharmaceutical formulations comprising said combination. ... | 03/22/2011 |
| 7906497 | Cancer treatment methods The invention provides methods to treating conditions such as prostate cancer, or for ameliorating one or more symptoms associated with prostate cancer, or for agents that modulate the biological activity of the androgen receptor. The invention also provides methods... | 03/15/2011 |
| 7879830 | Hormone replacement composition and method Hormone compositions including bioidentical hormones dispersed in a lipid-based cream are provided in syringes for dispensation and self-administration by a user. The compositions, which are topically applied by the user, are percutaneously delivered to the vascular... | 02/01/2011 |
| 7871994 | Hormone replacement therapy method and its administration form Method for hormone replacement therapy, in which at least in the established postmenopause a daily unit with at least one hormonal component, namely with at least estrogen (E) and/or at least one gestagen (G) is administered permanently and continuously every day, c... | 01/18/2011 |
| 7858604 | Method of treating human volume expansion mediated hypertension employing resibufogenin A method of treating volume expansion mediated hypertension including administering a therapeutically effective dose of resibufogenin to a patient having volume expansion mediated hypertension. A method for the determination of the presence of volume expansion media... | 12/28/2010 |
| 7858605 | Oral contraceptives to prevent pregnancy and diminish premenstrual symptomatology This invention relates to a method of preventing pregnancy and treating PMS including PMDD. More particularly, the invention relates to a method, which involves administering one of several combination oral contraceptive regimens in combination with an antidepressan... | 12/28/2010 |
| 7855190 | Methods of hormonal treatment utilizing contraceptive regimens with continuous estrogen administration The present invention provides contraceptive regimens in which a female is administered a combined dosage form of estrogen and progestin followed by a period of administration of estrogen. The disclosed contraceptive regimens can be administered to a female as a met... | 12/21/2010 |
| 7833994 | Ethanol extraction of phytosterols from corn fiber The present invention provides a process for extracting sterols from a high solids, thermochemically hydrolyzed corn fiber using ethanol as the extractant. The process includes obtaining a corn fiber slurry having a moisture content from about 20 weight percent to a... | 11/16/2010 |
| 7799769 | Transdermal compositions and methods for treatment of fibromyalgia and chronic fatigue syndrome Compositions and methods for alleviating the symptoms associated with chronic fatigue syndrome and fibromyalgia syndrome are provided. The compositions are based on use of a transdermal gel formulation delivery system for androgens, either alone or in combination wi... | 09/21/2010 |
| 7776845 | Pharmaceutical compositions The invention provides methods to treating conditions such as prostate cancer, or for ameliorating one or more symptoms associated with prostate cancer, or for agents that modulate the biological activity of the androgen receptor. The invention also provides methods... | 08/17/2010 |
| 7772219 | Methods of hormonal treatment utilizing extended cycle contraceptive regimens The present invention provides extended cycle contraceptive regimens in which a female is administered a combined dosage form of estrogen and progestin. The disclosed extended cycle contraceptive regimens can be administered to a female as a method of providing non-... | 08/10/2010 |
| 7759329 | Method of treating human preeclampsia employing resibufagenin A method of treating preeclampsia including administering a therapeutically effective dose of resibufagenin to a patient having preeclampsia. Effecting the determination of the presence of preeclampsia may be by determining whether there has been a substantial eleva... | 07/20/2010 |
| 7732431 | Pharmaceutical compositions comprising trimegestone The invention concerns a pharmaceutical composition comprises trimegestone optionally associated with an oestrogen, characterized in that it comprises a buffer solution whereof the pH, when it is introduced in the composition, ranging essentially between 2 and 5.5. ... | 06/08/2010 |
| 7704983 | Antiprogestin method for reducing side effects associated with low dosage HRT and oral contraception Menses regulation and, when desired, contraception is achieved at low doses of estrogen and progestin, which otherwise would create episodes of breakthrough bleeding and/or withdrawal amenorrhea, by periodically inducing menses with an antiprogestin. ... | 04/27/2010 |
| 7704984 | Extended estrogen dosing contraceptive regimen A method of contraception that provides for sequentially administering to a female of child bearing age: (a) a first composition containing a progestin in an amount equivalent to about 0.3 to about 1.5 mg norethindrone acetate and an estrogen in an amount equivalent... | 04/27/2010 |
| 7696189 | Prostate and breast cancer treatment The invention provides methods to treating conditions such as prostate cancer, or for ameliorating one or more symptoms associated with prostate cancer, or for agents that modulate the biological activity of the androgen receptor. The invention also provides methods... | 04/13/2010 |
| 7691835 | Formulations The invention provides methods to treating conditions such as prostate cancer, or for ameliorating one or more symptoms associated with prostate cancer, or for agents that modulate the biological activity of the androgen receptor. The invention also provides methods... | 04/06/2010 |
| 7687484 | Transporter enhanced corticosteroid activity Methods and compositions for enhancing the activity and/or duration of action of loteprednol etabonate and other soft anti-inflammatory steroids of the haloalkyl 17α-alkoxycarbonyloxy-11β-hydroxyandrost-4-en-3-one-17β-carboxylate type and the corresponding Δ | 03/30/2010 |
| 7629334 | Mesoprogrestins (progesterone receptor modulations) as a component of compositions for hormone replacement therapy (HRT) The use of mesoprogestins as pharmaceutical components for the manufacture of a medicament for hormone replacement therapy (HRT) and as components for the combined use together with an estrogen for the manufacture of a medicament for HRT as well as in respective HRT... | 12/08/2009 |
| 7615545 | Oral contraceptives to prevent pregnancy and diminish premenstrual symptomatology This invention relates to a method of preventing pregnancy and treating PMS including PMDD. More particularly, the invention relates to a method, which involves administering one of several combination oral contraceptive regimens in combination with an antidepressan... | 11/10/2009 |
| 7601707 | Method for instantly relieving tissue inflammation A method for treating an inflamed tissue includes locally applying a solution comprising a corticosteroid and an anesthetic agent to the inflamed tissue so that the solution directly contacts the inflamed tissue. The corticosteroid may be a 4 mg/ml dexamethasone sol... | 10/13/2009 |
| 7589082 | Pharmaceutical formulation for contraception and hormone-replacement therapy The present invention provides slow release estradiol-progesterone formulations that can be used in either contraception or hormone replacement therapies. The formulations comprise shaped particles of estradiol that is in a hemicrystalline form that exhibits especia... | 09/15/2009 |
| 7572779 | Oral pharmaceutical products containing 17β-estradiol-3-lower alkanoate, method of administering the same and process of preparation A pharmaceutical dosage unit for oral administration to a human female comprising a therapeutically effective amount of 17β-estradiol-3-lower alkanoate, most preferably 17β-estradiol-3-acetate, and a pharmaceutically acceptable carrier is disclosed. Also disclosed... | 08/11/2009 |
| 7569560 | Extended cycle multiphasic oral contraceptive method A multiphasic method of contraception provides for sequentially administering to a female of child bearing age: (a) a Phase I composition containing a progestogen and an estrogen for about 4 to about 7 days; (b) a Phase II composition containing a progestogen and an... | 08/04/2009 |
| 7560448 | Enhancement of activity and/or duration of action of soft anti-inflammatory steroids for topical or other local application Methods and compositions for enhancing the activity and/or duration of action of loteprednol etabonate and other soft anti-inflammatory steroids of the haloalkyl 17α-alkoxycarbonyloxy-11β-hydroxyandrost-4-en-3-one-17β-carboxylate type and the corresponding Δ | 07/14/2009 |
| 7524833 | Method and apparatus for concentrating and stabilizing conjugated estrogens from mare urine A method and apparatus for concentrating and stabilizing conjugated estrogens from pregnant mare urine on solid adsorbent supports to obtain a starting material for pharmaceuticals that contain a natural mixture of conjugated estrogen mixtures on cartridges in the v... | 04/28/2009 |
| 7439235 | Method for obtaining estrogens from mare's urine A method for obtaining an extract from a natural mixture of conjugated estrogens from the urine of pregnant mares (PMU) by solid-phase extraction on semipolar adsorption resins in which the resulting extract meets the pharmaceutical specifications for conjugated est... | 10/21/2008 |