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...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.

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Class 514/170 - Plural Compounds containing cyclopentanohydrophenanthrene ring systems


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein two or more bioactive compounds are
No. of patents: 371
Last issue date: 01/24/2012


1                    
NumberTitleIssue Date
8101592Hexahydro-cyclooctyl pyrazole cannabinoid modulators
This invention is directed to a hexahydro-cyclooctyl pyrazole cannabinoid modulator compound of formula (I): and a method for use in treating, ameliorating or preventing a cannabinoid receptor mediated syndrome, disorder or...
01/24/2012
8097604Combination of gestagen and insulin sensitizer for treating PCOS
The present invention relates to a medicament which contains as the active ingredient combination at least one gestagen with a contraceptive action as the sole hormone component and at least one insulin sensitizer, which medicament is in particular suitable for prev...
01/17/2012
8080539Method of treating human preeclampsia employing resibufagenin
A method of treating preeclampsia including administering a therapeutically effective dose of resibufagenin to a patient having preeclampsia. Effecting the determination of the presence of preeclampsia may be by determining whether there has been a substantial eleva...
12/20/2011
8076316Steroid compounds and formulations
The invention provides methods to treating conditions such as prostate cancer, or for ameliorating one or more symptoms associated with prostate cancer, or for agents that modulate the biological activity of the androgen receptor. The invention also provides methods...
12/13/2011
8071577Multi-phase contraceptive preparation based on a natural estrogen
The multiphase preparation having higher contraceptive safety and reduced side effects is based on a combination of a natural oestrogen with dienogest or drospirenone. The multiphase preparation is characterized by a first phase consisting of 2 daily dose units of 3...
12/06/2011
8071576Method of preventing or treating benign gynaecological disorders
The present invention relates to a method of preventing or treating benign estrogen sensitive gynecological disorders in a female mammal, wherein the method comprises the administration to said female mammal of a combination of progestogen and androgen in an amount ...
12/06/2011
8067400Androgen treatment in females
A method of improving cumulative embryo score may comprise administering an androgen to a human female for at least about four consecutive months followed by harvesting and fertilizing oocytes and forming embryos. A method of increasing the quantity of fertilized oo...
11/29/2011
8067399Method and apparatus for transdermal or transmucosal application of testosterone
Methods, formulations, and devices for providing transdermal or transmucosal delivery of active agents to subjects in need thereof. The formulations and methods treat symptoms of hormonal disorders including hypogonadism, female sexual desire disorder, female menopa...
11/29/2011
8063030Extended cycle multiphasic oral contraceptive method
A multiphasic method of contraception comprising the steps of sequentially administering to a female of child bearing age a Phase I composition containing a progestogen in an amount equivalent to about 0.3 to about 1.5 mg norethindrone acetate and an estrogen in an ...
11/22/2011
8048868Method of preventing preeclampsia
A method of preventing preeclampsia including administering to a patient during an early stage of pregnancy a prophylactically-effective amount of resibufogenin. The administration of resibufogenin is periodically repeated. The method serves to prevent hypertension,...
11/01/2011
8022052Inhibition of PPAR gamma expression by specific osteogenic oxysterols
This invention relates to methods for using agents to inhibit peroxisome proliferator activated receptor expression. ...
09/20/2011
7964586Method for obtaining a natural mixture of conjugated equine estrogens
A method for obtaining an extract containing the natural mixture of conjugated equine estrogens in which a mixture of conjugated estrogens obtained by solid-phase extraction from pregnant mares' urine is depleted in phenolic urine contents and in non-conjugated lipo...
06/21/2011
7935691Extended cycle multiphasic oral contraceptive kit
A multiphasic contraceptive kit for use to practice a multiphasic method of contraception that provides for sequentially administering to a female of child bearing age: (a) a Phase I composition containing a progestogen and an estrogen for about 4 to about 7 days; (...
05/03/2011
7910570Composition comprising a combination of an aromatase inhibitor, a progestin and an oestrogen and its use for the treatment of endometriosis
The invention relates to a method of treating endometriosis using a combination of an aromatase inhibitor, a progestin and an oestrogen. The invention also relates to pharmaceutical formulations comprising said combination. ...
03/22/2011
7906497Cancer treatment methods
The invention provides methods to treating conditions such as prostate cancer, or for ameliorating one or more symptoms associated with prostate cancer, or for agents that modulate the biological activity of the androgen receptor. The invention also provides methods...
03/15/2011
7879830Hormone replacement composition and method
Hormone compositions including bioidentical hormones dispersed in a lipid-based cream are provided in syringes for dispensation and self-administration by a user. The compositions, which are topically applied by the user, are percutaneously delivered to the vascular...
02/01/2011
7871994Hormone replacement therapy method and its administration form
Method for hormone replacement therapy, in which at least in the established postmenopause a daily unit with at least one hormonal component, namely with at least estrogen (E) and/or at least one gestagen (G) is administered permanently and continuously every day, c...
01/18/2011
7858604Method of treating human volume expansion mediated hypertension employing resibufogenin
A method of treating volume expansion mediated hypertension including administering a therapeutically effective dose of resibufogenin to a patient having volume expansion mediated hypertension. A method for the determination of the presence of volume expansion media...
12/28/2010
7858605Oral contraceptives to prevent pregnancy and diminish premenstrual symptomatology
This invention relates to a method of preventing pregnancy and treating PMS including PMDD. More particularly, the invention relates to a method, which involves administering one of several combination oral contraceptive regimens in combination with an antidepressan...
12/28/2010
7855190Methods of hormonal treatment utilizing contraceptive regimens with continuous estrogen administration
The present invention provides contraceptive regimens in which a female is administered a combined dosage form of estrogen and progestin followed by a period of administration of estrogen. The disclosed contraceptive regimens can be administered to a female as a met...
12/21/2010
7833994Ethanol extraction of phytosterols from corn fiber
The present invention provides a process for extracting sterols from a high solids, thermochemically hydrolyzed corn fiber using ethanol as the extractant. The process includes obtaining a corn fiber slurry having a moisture content from about 20 weight percent to a...
11/16/2010
7799769Transdermal compositions and methods for treatment of fibromyalgia and chronic fatigue syndrome
Compositions and methods for alleviating the symptoms associated with chronic fatigue syndrome and fibromyalgia syndrome are provided. The compositions are based on use of a transdermal gel formulation delivery system for androgens, either alone or in combination wi...
09/21/2010
7776845Pharmaceutical compositions
The invention provides methods to treating conditions such as prostate cancer, or for ameliorating one or more symptoms associated with prostate cancer, or for agents that modulate the biological activity of the androgen receptor. The invention also provides methods...
08/17/2010
7772219Methods of hormonal treatment utilizing extended cycle contraceptive regimens
The present invention provides extended cycle contraceptive regimens in which a female is administered a combined dosage form of estrogen and progestin. The disclosed extended cycle contraceptive regimens can be administered to a female as a method of providing non-...
08/10/2010
7759329Method of treating human preeclampsia employing resibufagenin
A method of treating preeclampsia including administering a therapeutically effective dose of resibufagenin to a patient having preeclampsia. Effecting the determination of the presence of preeclampsia may be by determining whether there has been a substantial eleva...
07/20/2010
7732431Pharmaceutical compositions comprising trimegestone
The invention concerns a pharmaceutical composition comprises trimegestone optionally associated with an oestrogen, characterized in that it comprises a buffer solution whereof the pH, when it is introduced in the composition, ranging essentially between 2 and 5.5. ...
06/08/2010
7704983Antiprogestin method for reducing side effects associated with low dosage HRT and oral contraception
Menses regulation and, when desired, contraception is achieved at low doses of estrogen and progestin, which otherwise would create episodes of breakthrough bleeding and/or withdrawal amenorrhea, by periodically inducing menses with an antiprogestin. ...
04/27/2010
7704984Extended estrogen dosing contraceptive regimen
A method of contraception that provides for sequentially administering to a female of child bearing age: (a) a first composition containing a progestin in an amount equivalent to about 0.3 to about 1.5 mg norethindrone acetate and an estrogen in an amount equivalent...
04/27/2010
7696189Prostate and breast cancer treatment
The invention provides methods to treating conditions such as prostate cancer, or for ameliorating one or more symptoms associated with prostate cancer, or for agents that modulate the biological activity of the androgen receptor. The invention also provides methods...
04/13/2010
7691835Formulations
The invention provides methods to treating conditions such as prostate cancer, or for ameliorating one or more symptoms associated with prostate cancer, or for agents that modulate the biological activity of the androgen receptor. The invention also provides methods...
04/06/2010
7687484Transporter enhanced corticosteroid activity
Methods and compositions for enhancing the activity and/or duration of action of loteprednol etabonate and other soft anti-inflammatory steroids of the haloalkyl 17α-alkoxycarbonyloxy-11β-hydroxyandrost-4-en-3-one-17β-carboxylate type and the corresponding Δ
03/30/2010
7629334Mesoprogrestins (progesterone receptor modulations) as a component of compositions for hormone replacement therapy (HRT)
The use of mesoprogestins as pharmaceutical components for the manufacture of a medicament for hormone replacement therapy (HRT) and as components for the combined use together with an estrogen for the manufacture of a medicament for HRT as well as in respective HRT...
12/08/2009
7615545Oral contraceptives to prevent pregnancy and diminish premenstrual symptomatology
This invention relates to a method of preventing pregnancy and treating PMS including PMDD. More particularly, the invention relates to a method, which involves administering one of several combination oral contraceptive regimens in combination with an antidepressan...
11/10/2009
7601707Method for instantly relieving tissue inflammation
A method for treating an inflamed tissue includes locally applying a solution comprising a corticosteroid and an anesthetic agent to the inflamed tissue so that the solution directly contacts the inflamed tissue. The corticosteroid may be a 4 mg/ml dexamethasone sol...
10/13/2009
7589082Pharmaceutical formulation for contraception and hormone-replacement therapy
The present invention provides slow release estradiol-progesterone formulations that can be used in either contraception or hormone replacement therapies. The formulations comprise shaped particles of estradiol that is in a hemicrystalline form that exhibits especia...
09/15/2009
7572779Oral pharmaceutical products containing 17β-estradiol-3-lower alkanoate, method of administering the same and process of preparation
A pharmaceutical dosage unit for oral administration to a human female comprising a therapeutically effective amount of 17β-estradiol-3-lower alkanoate, most preferably 17β-estradiol-3-acetate, and a pharmaceutically acceptable carrier is disclosed. Also disclosed...
08/11/2009
7569560Extended cycle multiphasic oral contraceptive method
A multiphasic method of contraception provides for sequentially administering to a female of child bearing age: (a) a Phase I composition containing a progestogen and an estrogen for about 4 to about 7 days; (b) a Phase II composition containing a progestogen and an...
08/04/2009
7560448Enhancement of activity and/or duration of action of soft anti-inflammatory steroids for topical or other local application
Methods and compositions for enhancing the activity and/or duration of action of loteprednol etabonate and other soft anti-inflammatory steroids of the haloalkyl 17α-alkoxycarbonyloxy-11β-hydroxyandrost-4-en-3-one-17β-carboxylate type and the corresponding Δ
07/14/2009
7524833Method and apparatus for concentrating and stabilizing conjugated estrogens from mare urine
A method and apparatus for concentrating and stabilizing conjugated estrogens from pregnant mare urine on solid adsorbent supports to obtain a starting material for pharmaceuticals that contain a natural mixture of conjugated estrogen mixtures on cartridges in the v...
04/28/2009
7439235Method for obtaining estrogens from mare's urine
A method for obtaining an extract from a natural mixture of conjugated estrogens from the urine of pregnant mares (PMU) by solid-phase extraction on semipolar adsorption resins in which the resulting extract meets the pharmaceutical specifications for conjugated est...
10/21/2008
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