Did You Know...
...that to encourage use of his new invention, the shopping cart, market owner Sylvan Goldman hired fake shoppers to push the carts around his store in Oklahoma City? Seems his customers were reluctant to give up their hand-carried baskets.
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| Number | Title | Issue Date |
| 8114858 | Derivatives of 4- or 5-aminosalicylic acid The present invention provides new derivatives of 4- or 5-aminosalicylic acid, and a pharmaceutical composition containing these derivatives of 4- or 5-aminosalicylic acid as active ingredients, useful for the treatment of intestinal diseases such as inflammatory bo... | 02/14/2012 |
| 7825106 | Modified release formulations and methods of treating inflammatory bowel disease Methods and formulations for treating inflammatory bowel disease are disclosed. The methods and formulations include, but are not limited to, methods and formulations for delivering effective concentrations of 4-aminosalicylic acid and/or 5-aminosalicylic acid, and ... | 11/02/2010 |
| 7417037 | Compositions and methods of treatment for inflammatory diseases Inflammatory bowel diseases are represented by two idiopathic disorders, which include ulcerative colitis and Crohn's disease. Ulcerative colitis is restricted to the colon and involves uncertain and inflammation of the lining (mucosa) of the large intestine. Crohn'... | 08/26/2008 |
| 7371896 | Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same The present invention relates to a tetrafluorobenzyl derivative and a pharmaceutical composition for prevention and treatment of acute and chronic neurodegenerative disease in central nervous system and ophthalmic diseases containing the same. The tetrafluorobenzyl ... | 05/13/2008 |
| 7354912 | Unique compositions of zwitterionic phospholipids and bisphosphonates and use of the compositions as bisphosphate delivery systems with reduced GI toxicity Compositions and methods for treating osteoporosis using the compositions are disclosed where the compositions have reduced GI toxicity and improved bio-availability and include a bisphosphonate and zwitterionic phospholipid. ... | 04/08/2008 |
| 7332629 | Modulators (inhibitors/activators) of histone acetyltransferases Disclosed are compounds of the formulae: and method of using the compounds to treat cancer, AIDS, HIV infection, and asthma. ... | 02/19/2008 |
| 7323452 | Method for the accelerated in vivo removal of ethanol A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as catalysts or “pseudo” enzymes for the oxidation. These additives... | 01/29/2008 |
| 7319160 | Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same The present invention relates to a tetrafluorobenzyl derivative and a pharmaceutical composition for prevention and treatment of acute and chronic neurodegenerative disease in central nervous system and ophthalmic diseases containing the same. The tetrafluorobenzyl ... | 01/15/2008 |
| 7259250 | C-nitroso compounds and use thereof A C-nitroso compound having a molecular weight ranging from 225 to 1,000 (from 225 to 600 for oral administration) on a monomeric basis wherein a nitroso group is attached to a tertiary carbon, which is obtained by nitrosylation of a carbon acid having a pKa less th... | 08/21/2007 |
| 7208483 | Polymeric delivery agents and delivery agent compounds Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 04/24/2007 |
| 7189878 | Tetrafluorobenzyl derivatives and pharmaceutical composition for preventing and treating acute and chronic neurodegenerative diseases in central nervous system containing the same The present invention relates to a tetrafluorobenzyl derivative and a pharmaceutical composition for prevention and treatment of acute and chronic neurodegenerative disease in central nervous system and ophthalmic diseases containing the same. The tetrafluorobenzyl ... | 03/13/2007 |
| 7151191 | Compounds and compositions for delivering active agents Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 12/19/2006 |
| 7122615 | Polyanhydrides with therapeutically useful degradation products An aromatic polyanhydride having a repeating unit with structure (I) wherein Ar is a substituted or unsubstituted aromatic ring and R is a difunctional organic moiety substituted on each Ar ortho to the anhydride group. Ortho-substituted bis-aromatic dicarboxylic ac... | 10/17/2006 |
| 7091327 | Process for the preparation of aromatic azo-compounds The present invention relates to a process for the preparation of aromatic azo-compounds, in particular 3,3′-azo-bis(6-hydroxybenzoic acid) (olsalazine) and its salts and derivatives. ... | 08/15/2006 |
| 7056903 | Carboxylic acid derivatives as IP antagonists This invention relates to compounds which are generally IP receptor antagonists and which are represented by Formula I: wherein: R1, R2, and R3 ... | 06/06/2006 |
| 7049308 | C-nitroso compounds and use thereof A C-nitroso compound having a molecular weight ranging from 225 to 1,000 (from 225 to 600 for oral administration) on a monomeric basis wherein a nitroso group is attached to a tertiary carbon, which is obtained by nitrosylation of a carbon acid having a pKa less th... | 05/23/2006 |
| 7048788 | Ship bottom paint using coal ash and diatomaceous earth A ship bottom paint additive to prevent or reduce marine life attachment to the bottoms of ships, and ship bottom paint comprises a mixture of coal ash and diatom earth or beer yeast diatom earth wherein the coal ash is preferably fly ash and the diatom earth or bee... | 05/23/2006 |
| 6924312 | Taxol enhancer compounds Disclosed is a compound represented by the Structural Formula (I): Y is a covalent bond, a phenylene group or a substituted or unsubstituted straight chained hydrocarbyl group. In addition, Y, ... | 08/02/2005 |
| 6903082 | Methods of treating inflammatory conditions of the gastrointestinal tract using 4-APAA and compositions thereof Compounds are disclosed having the structure of Formula I: where R1, R3, and R4 are independently hydrogen or C1 to C4 alkyl, and R2 is: | 06/07/2005 |
| 6855341 | Anti-viral compositions and methods of making and using the anti-viral compositions Disclosed are anti-viral compositions containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients), and a pharmaceutical carrier. Also disclosed are methods of treating lesionous symptoms of a viral infection involvi... | 02/15/2005 |
| 6833362 | Method and composition for the accelerated in vivo removal of ethanol A composition for accelerating the disposal of ethanol from bodily fluid. Certain additives can accelerate the metabolic oxidation of ethanol, and others in addition act as catalysts or “pseudo” enzymes for the oxidation. Additives include the oxidant Nicotinami... | 12/21/2004 |
| 6730329 | Zinc containing compositions for anti-viral use One aspect of the invention relates to anti-viral composition containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients such as at least one analgesic) at least one hydrocarbyl containing compound, and water. Anoth... | 05/04/2004 |
| 6706290 | Methods for eradication of nanobacteria Nanobacteria contribute to pathological calcification in the human and animal body, including diseases such as kidney stones, salivary gland stones, dental pulp stones and atherosclerosis. The present invention provides methods for sterilizing articles contaminated ... | 03/16/2004 |
| 6624153 | Halogenated antituberculosis agents Halogenated derivatives of two synthetic anti-tuberculosis agents, thioacetazone and p-aminosalicylic acid, have been synthesized. In general, the halogenated compound has the structure of Structure I: ##STR1## wherein X1 is a halogen and X | 09/23/2003 |
| 6620785 | Treatment of Mycobacterial diseases by administration of bactericidal/permeability-increasing protein products The present invention relates to methods for treating a subject suffering from infection with Mycobacteria, such as M. leprae or M. tuberculosis comprising administering to the subject a composition comprising a bactericidal/permeability-inducing (BPI) pr... | 09/16/2003 |
| 6593339 | Use of compounds as antibacterial agents The present invention discloses a new use of NO-releasing NSAIDs, especially NO-releasing NSAIDs of the formula I, or a pharmaceutically acceptable salt or enantiomer thereof, for the manufacture of a medicament for the treatment of bacterial infections, ... | 07/15/2003 |
| 6589944 | Breakers of advanced glycation endproducts Advanced glycation endproducts (AGEs) have been implicated in the pathogenesis of a variety of debilitating diseases such as diabetes, atherosclerosis, Alzheimer's and rheumatoid arthritis, as well as in the normal aging process. Five compounds are here r... | 07/08/2003 |
| 6551620 | Pellet formulation for the treatment of the intestinal tract An orally adminsterable pharmaceutical pellet formulation for the treatment of the intestinal tract is disclosed, which comprises a core and an enteric coating, the core including, as a pharmaceutical active compound, aminosalicylic acid or a pharmaceutic... | 04/22/2003 |
| 6482846 | Compositions and methods to prevent toxicity induced by nonsteroidal antiinflammatory drugs Nonsteroidal antiinflammatory drugs which have been substituted with a nitrogen monoxide group; compositions comprising (i) a nonsteroidal antiinflammatory drug, which can optionally be substituted with a nitrogen monoxide group and (ii) a compound that d... | 11/19/2002 |
| 6475526 | Zinc containing compositions for anti-viral use One aspect of the invention relates to anti-viral composition containing at least one zinc compound and at least one phenolic antioxidant (and optionally other ingredients such as at least one analgesic) at least one hydrocarbyl containing compound, and w... | 11/05/2002 |
| 6455515 | Salicylohydrazide derivatives, processes and intermediates for their preparation, compositions comprising them, and their use Salicylohydrazide derivatives of the formula I ##STR1## in which the index and the substituents have the following meanings: X is halogen, NO2, cyano, alkyl or alkoxy; m is 0, 1, 2 or 3, it being possible for the substituents X to differ from each o... | 09/24/2002 |
| 6426338 | Therapy for constipation Compositions comprising colchicine and at least one amino-salicylic acid derivative, preferably olsalazine is used for treatment of prophylaxis of constipation.... | 07/30/2002 |
| 6326364 | Use of 5-aminosalicylates as antimicrobial agents A method of inhibiting the growth of a bacterial species in a human or non-human vertebrate employs the antimicrobial (i.e., antibiotic) properties of 5-aminosalicylates. These antimicrobial properties are also employed in an antimicrobial method of inhib... | 12/04/2001 |
| 6287601 | Topical nitric oxide donor compositions Compositions and methods of the topical treatment of equine laminitis are disclosed. In particular, combinations of a fast acting nitric oxide (NO) donor, a sustained acting NO donor and an NSAID mixed in a lipid-based carrier are described. The applicati... | 09/11/2001 |
| 6277412 | Pellet-type formulation intended for treating the intestinal tract An orally adminsterable pharmaceutical pellet formulation for the treatment of the intestinal tract is disclosed, which comprises a core and an enteric coating, the core including, as a pharmaceutical active compound, aminosalicyclic acid or a pharmaceuti... | 08/21/2001 |
| 6255298 | Macrophage scavenger receptor antagonists for use in the treatment of cardiovascular diseases Salicylanilide derivatives which are macrophagescavenger receptor antagonists are provided. Methods of treating cardiovascular disease comprising administration of the present compounds are also provided. The present compounds inhibit lipid accumulation w... | 07/03/2001 |
| 6225296 | Inhibitory effects of synthetic and natural colorant on carcinogenesis VIII A method of inhibiting Epstein-Barr virus early antigen induction in Epstein-Barr virus genome-carrying cells which have been cultivated in vitro in a medium containing at least one chemical selected from the group consisting of tumor-inducing chemicals a... | 05/01/2001 |
| 6177414 | Starburst conjugates Starburst conjugates which are composed of at least one dendrimer in association with at least one unit of a carried agricultural, pharmaceutical, or other material have been prepared. These conjugates have particularly advantageous properties due to the ... | 01/23/2001 |
| 6143734 | Nitroso esters of ଲ-oxo-amides and aryl propionic acid derivatives of non-steroidal antiinflammatory drugs A compound comprising a non-steroidal antiinflammatory agent to which is directly or indirectly linked an NO group, a compound comprising an enolic anilide non-steroidal antiinflammatory agent to which is directly or indirectly linked an NO2 gr... | 11/07/2000 |
| 6143735 | Agent for treating heart diseases Vitamin E acts to enhance and improve the effect upon oral administration of coronary active vasodilators and/or blood circulation-promoters. The new use and new agents containing vitamin E are described.... | 11/07/2000 |
