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...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.

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Class 514/157 - The hetero ring is six-membered and includes at least two nitrogens and no other hetero atoms


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the heterocyclic ring has six members
No. of patents: 95
Last issue date: 12/29/2009


1      
NumberTitleIssue Date
7638506Granular agrochemical composition
Provided is a granular agrochemical composition by which the problems accompanying the prior art granular agrochemical compositions can be overcome, which can be prepared in a simple formulation and by which sustained releasability of the agrochemically active ingre...
12/29/2009
7347984Mammalian agmatinase inhibitory substance
The present invention provides for methods and compounds for treating brain trauma and disorders such as: ischemia, stroke, neurodegenerative disorders, opioid addiction, idiopathic pain, epilepsy, and depression. More specifically, the invention provides methods fo...
03/25/2008
7320967Cosmetic composition, method of cosmetic treatment and preparation of a composition for promoting the growth and/or preventing or delaying the loss of hair
The invention relates to a cosmetic composition containing at least one 15-hydroxy-prostaglandin dehydrogenase inhibitor and cosmetically acceptable excipients. It also relates to a method of cosmetic treatment for promoting the growth and/or preventing or delaying ...
01/22/2008
7211696Antileishmanial dinitroaniline sulfanomides with activity against parasite tubulin
Dinitroaniline compounds useful for the treatment of diseases caused by parasitic protozoa in subjects in need of such treatment. The compounds are particularly useful in the treatment of leishmaniasis. The compounds are preferably less cytotoxic to normal cells tha...
05/01/2007
7048937Methods and compositions for control of coccidiosis
Feeding yeast cell wall-containing compositions, including those compositions comprising mannanoligosaccharide(s), to animals exposed to or infected with coccidia, especially poultry exposed to pathogenic species of Eimeria, results in improved livestock perf...
05/23/2006
7001924Inhibitors of RNase P proteins as antibacterial compounds
The present invention features compounds useful for inhibiting RNase P activity. These compounds can be used as therapeutics for treating or preventing a variety of bacterial infections. The compounds belong to several classes including mono- and bis-guanylhydrazone...
02/21/2006
6974593Insoluble drug delivery
Particles of water insoluble biologically active compounds, particularly water-insoluble drugs, with an average size of 100 nm to about 300 nm, are prepared by dissolving the compound in a solution then spraying the solution into compressed gaz, liquid or supercriti...
12/13/2005
6974825Compounds with analgesic effect
Compounds of general formula (I) wherein m is 0 or 1, and n is 1 or 2; are disclosed and claimed in the present application, as well as their pharmaceutically acceptable salts, pharmaceutical compositions comp...
12/13/2005
6777000In-situ gel formation of pectin
In-situ gelation of a pectic substance. Composition, method of preparation, and method of use of a pectin in-situ gelling formulation for the delivery and sustained release of a physiologically active agent to the body of an animal. The pectin can be isolated from A...
08/17/2004
6573254Method for the stimulation of sperm production and gonadal development in animals
Disclosed is a method to stimulate or enhance sperm development in males and gonadal development in females by administration of an agent which results in a transiently level of a thyroid hormone such as T3 and increased gonadotropin levels in ...
06/03/2003
6432935Pharmaceutical compositions, mainly vaginal suppository, containing many different active ingredients
Compositions comprising an antibiotic, sulphonamide, at least one an antiquagul agent, e.g., clotrimazol (bis-phenyl-(2-chlorophenyl)-1-imidazolyl-methane), natamycin, or nystatin,and 5-nitro-metronidazol (5-nitro-inidazoles) e.g., (metronidazol or t...
08/13/2002
6180633Drug resistance and multidrug resistance modulators
Drug and multidrug resistant modulators of the formula: ##STR1## where R1 and R2 are independently hydrogen or halo; A is --CH2 --CH2 --, --CH2 --CHR4 --CH2 --, or --CH2
01/30/2001
5725875Protective skin composition
A protective cream composition contains 15 to 40 wt % of an alkali metal fatty acid salt having from 8 to 18 carbon atoms, an effective amount of a topical agent such as an antimicrobial compound, 5 to 20 wt. % of a polyol effective as an emollient, 0.5 t...
03/10/1998
5370876Antimicrobial protective skin composition and method for protecting skin from body fluids
A protective cream composition contains 15 to 40 wt. % of an alkali metal fatty acid salt having from 8 to 18 carbon atoms, an effective amount an antimicrobial compound, 5 to 20 wt. % of a polyol effective as an emollient, 0.5 to 8.0 wt. %, of an alkali ...
12/06/1994
5335675Stress-softened elastomeric films, articles, and method and apparatus for making such films and articles
A stress-softened thermoplastic elastomeric (TPE) film which has been subjected to tensional deformation comprising at least uniaxial strain, and having improved textural and thermal transmissivity characteristics, as compared to a native, unstretched mat...
08/09/1994
5330980Medicament for the topical treatment of skin
A medicament for the topical treatment of burned, irritated, ulcered, chafed, or infected, skin, a method of making the medicament, and a method of use of the medicament, the medicament comprising: about 70.6% by weight of Petrolatum U.S.P.(Vaseline); abo...
07/19/1994
5273970Treatment of protozoal diseases
The antibacterial substance baquiloprim (2,4-diamino-5-[8-dimethylamino-7-methyl-5-quinolylmethyl]pyrimidine) is shown to be active against protozoal infections, e.g. toxoplasmosis. Preferably the baquiloprim is administered together with a sulphonamide....
12/28/1993
5258373Anticoccidial compositions
Compositions comprising a mixture of the antibiotic frenolicin B with a potentiated sulfonamide anticoccidial agent, useful for the treatment and prevention of coccidiosis in animals and methods of treating coccidiosis are disclosed....
11/02/1993
5179127Halopropargyl acyl compound, compositions, microbicidal uses and processes of preparation
Compounds of the formula ##STR1## wherein A is selected from the group consisting of (1) phenyl, (2) naphthyl, (3) phenyl substituted with one or more halo, cyano, (C1 -C4)alkyl, nitro, (C1 -C4)haloalkyl, a...
01/12/1993
5135924Therapeutic treatment of animals with oral administration of ormetoprim-potentiated sulfonamides
Systemic bacterial infections caused by aerobic and anaerobic organisms in companion animals such as dogs can be treated effectively and conveniently by the oral administration on a once a day basis of an antibacterial combination of ormetoprim and a sulf...
08/04/1992
5096896Sustained release compositions
A non-crosslinked derivative formable by reacting at least one substituted or unsubstituted, saturated or unsaturated, mono-, di- or poly-carboxy, hydroxy or mercapto hydrocarbon with at least one cyclic unsaturated (thio)ether....
03/17/1992
5063219Anticoccidial composition
Compositions comprising a mixture of a 2,4-diamino-5-(trisubstituted)benzyl-pyrimidine potentiated sulfonamide antibiotic with an ionophorous polyether anticoccidial agent are useful for the treatment and prevention of coccidiosis in animals....
11/05/1991
5013306Anti-infective and antithrombogenic medical articles and method for their preparation
An anti-infective medical article has chlorhexidine bulk distributed throughout a polyurethane base layer and may have a coating layer on the base layer. The coating layer may be chlorhexidine permeated into the surface or it may be an antibiotic, antithr...
05/07/1991
4999210Anti-infective and antithrombogenic medical articles and method for their preparation
An anti-infective medical article has chlorhexidine bulk distributed throughout a polyurethane base layer and may have a coating layer on the base layer. The coating layer may be chlorhexidine, an antibiotic, or an antithrombogenic agent permeated into th...
03/12/1991
4996198Anticoccidial composition
Compositions comprising a mixture of a 2,4-diamino-5-(trisubstituted)benzyl-pyrimidine potentiated sulfonamide antibiotic with an ionophorous polyether anticoccidial agent are useful for the treatment and prevention of coccidiosis in animals....
02/26/1991
4956354Therapeutic preparation for use on skin
A therapeutic preparation for the treatment of skin problems. More particularly, the preparation is a mixture including almond oil, sulfathiazole, water and paraffin wax....
09/11/1990
4931433Method for treating certain neoplastic diseases
Compounds of formula I are formulated with a pharmaceutical carrier for the treatment of neoplastic disease sensitive to treatment with the compounds in animals including humans. ##STR1## wherein: Y is a substituent attached to any of the unsubstitut...
06/05/1990
4871722Synergistic veterinary composition and/or fodder premix and process for preparing same
The invention relates to a synergistic veterinary composition and/or a fodder premix useful for preventing or curing bacterial, fungal and protozoic infection particularly occurring at poultry species. Furthermore the invention relates to a process for pr...
10/03/1989
4818753Synthesis and method of use for 2, 4 diaminoquinazoline
Compounds of the formula ##STR1## wherein R1 is H, methyl, ethyl, or chloro and R2 is hydrocarbyl of 1-12 C are useful as antifungal agents. Compounds of this series wherein R2 is 7-12 C are novel. A new synthetic met...
04/04/1989
47925519-anthryloxyaminoalkanes and related compounds as anti-inflammatory and analgetic agents
Compounds useful for treating inflammation, pain and swelling, represented by the formula: ##STR1## and the pharmaceutically acceptable acid addition salts thereof, wherein: Y and Z are each independently halo, alkyl or alkoxy; l and m are each indep...
12/20/1988
4781920Anthelmintic paste compositions containing resinates of d1-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole
The invention provides physically stable anthelmintic paste compositions containing resinates of d1-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole and other anthelmintic compounds in combination with a wide variety of therapeutic agents such as an...
11/01/1988
4735959Carboxylic acid amides and pharmaceutical compositions containing them
There are described novel carboxylic acid derivatives of the formula ##STR1## and derivatives of the formula ##STR2## and the addition salts thereof, which exhibit an effect on the intermediary metabolism. Furthermore, the compounds of Formula I...
04/05/1988
4696921Antimalarial pharmaceutical compositions
Mixtures of active substances and pharmaceutical compositions useful in malaria therapy comprising a quinolinemethanol derivative of the formula ##STR1## wherein R1 is hydrogen, fluorine, chlorine, bromine, methyl or trifluoromethyl, R
09/29/1987
4677143Antimicrobial compositions
Antimicrobial compositions finding particular utility for coating access systems, lead devices including shunts, cannulae, catheters, catheter adapters, wires and other solid or hollow tubular devices used for a variety of medical purposes is provided. Th...
06/30/1987
4654323Method and composition for the therapeutic and prophylactic treatment of trauma to the skin
A novel method and composition are disclosed for the therapeutic and prophylatic treatment of trauma to the skin. In particular, burns, sunburn and frostbite are treated with compounds that have the ability to interfere with the action of calcium calmodul...
03/31/1987
4612337Method for preparing infection-resistant materials
An infection-resistant polymeric material, such as polytetrafluoroethylene, for use on or within a human or animal body, for example, in the form of a vascular graft, can be prepared by an improved method which comprises the following sequence of steps: (...
09/16/1986
4599226Wound dressing comprising silver sulfadiazine incorporated in animal tissue and method of preparation
Animal tissue and the like having silver sulfadiazine incorporated therein is useful as a covering for burns and/or wounds. The silver sulfadiazine is incorporated in the tissue by soaking the tissue in an ammoniacal silver sulfadiazine solution or suspen...
07/08/1986
4581028Infection-resistant materials and method of making same through use of sulfonamides
Infection-resistant materials, and methods of preparing same, suitable for use within the interior of a human or animal body in such forms as vascular grafts prostheses, or other implanted devices. The material is rendered infection-resistant by incorpora...
04/08/1986
4579731Polymeric diffusion burn matrix and method of use
A protective skin matrix is provided which is particularly suited for the protection of burned or wounded patients. The matrix may be either cured, applied in sheets, or painted or sprayed directly onto the burned or wounded patient. The protective skin m...
04/01/1986
4562211Pharmaceutically active 2-substituted-1-(omega-aminoalkoxy)benzenes
2-Substituted-1-(omega-aminoalkoxy)benzenes are prepared and found useful as pharmaceutical agents, particularly as antidepressants....
12/31/1985
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