Did You Know...
...that a workman who left the soap mixing machine on too long was responsible for making Ivory Soap? He was so embarrassed by his mistake that he threw the mess in a stream. Imagine his dismay when the evidence of his error floated to the surface! Result: Ivory soap, the soap that floats.
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| Number | Title | Issue Date |
| 7935688 | Vitamin D-like compound The present invention provides a compound represented by the following general formula (I): or a pharmaceutically acceptable salt thereof, a pharmaceutical composition containing such a compound, and the like. The compound ... | 05/03/2011 |
| 7435408 | Porous particles comprising excipients for deep lung delivery Improved porous particles for drug delivery to the pulmonary system, and methods for their synthesis and administration are provided. In a preferred embodiment, the porous particles are made of a biodegradable material and have a mass density less than 0.4 g/cm... | 10/14/2008 |
| 7338971 | Treatment of inflammatory, cancer, and thrombosis disorders This invention provides for the treatment of inflammatory, cancer and thrombotic disorders through the administration, in combination, of a COX2 inhibitor, low dose aspirin, and antioxidant flavanoids, flavonoids or isoflavones and at least one of these combinations... | 03/04/2008 |
| 7329402 | Methods of imaging and treatment Novel ultrasound methods comprising administering to a patient a targeted vesicle composition which comprises vesicles comprising a lipid, protein or polymer, encapsulating a gas, in combination with a targeting ligand, and scanning the patient using ultrasound. The... | 02/12/2008 |
| 7208629 | 5′-Carbamoyl-1,1-biphenyl-4-carboxamide derivatives and their use as p38 kinase inhibitors Compounds of formula (I): wherein when m is 0 to 4 R1 is selected from C1–6alkyl, C3–7cycloalkyl, C2–6alkenyl, —SO2NR4R5, —CONR4R5 and —COOR4; and when m is 2 to 4 R1 is additionally selected from C1–6alkoxy, hydroxy, NR4R5, —NR4SO2R5, —NR4SOR5, â€... | 04/24/2007 |
| 7198949 | Compositions and methods for altering the biodistribution of biological agents The invention relates to a new and improved pharmaceutical composition and method for delivery of therapeutic agents. The methods and composition of the invention can be used with several therapeutic agents and can achieve site specific delivery of a therapeutic or ... | 04/03/2007 |
| 7105151 | Oxygen delivery agents and uses for the same The present invention describes, inter alia, oxygen delivery agents or blood substitutes comprising a fluorinated gas and a stabilizing material, uses for the oxygen delivery agents or blood substitutes, and apparatus for making and delivering the oxygen delivery ag... | 09/12/2006 |
| 7083572 | Therapeutic delivery systems Targeted therapeutic delivery systems comprising gas- or gaseous precursor-filled lipid microspheres comprising a therapeutic are described. Methods for employing such microspheres in therapeutic delivery applications are also provided. Targeted therapeutic d... | 08/01/2006 |
| 7078015 | Ultrasound imaging and treatment Methods of and apparatus for preparing temperature activated gaseous precursor-filled liposomes are described. Gaseous precursor-filled liposomes prepared by these methods are particularly usefull for example, in ultrasonic imaging applications and in therapeutic dr... | 07/18/2006 |
| 6998107 | Composition comprising low density microspheres Low density microspheres, methods for preparing same, and use of same as contrast agents are described. The microspheres have a void having a volume that comprises at least about 75% of the total volume of the microspheres, and which contains a gas or the vapor of a... | 02/14/2006 |
| 6927197 | Antibacterial compositions and method of using same Antibacterial solution useful as a cleaning agent suitable for cutaneous use by humans or otherwise which is aqueous based, free of alcohol and surfactants and having a quaternary ammonium compound as its principal antimicrobial agent, a number of moisturizing agent... | 08/09/2005 |
| 6867229 | Antiparasitic composition for the treatment and protection of pets Composition which is useful in particular for the treatment and protection of domestic animals which are infested with parasites or are likely to be infested with them, these compositions comprising, in the form of a ready-to-use solution: ... | 03/15/2005 |
| 6479456 | Antimicrobial perfume compositions An antimicrobial perfume compositions that contain a perfume ingredient having antimicrobial activity of at least 80% as measured by the "agar surface coating test," the "vapor phase test," or by the "direct spray method." The active ingredient is grapefr... | 11/12/2002 |
| 6395765 | Antiparasitic composition for the treatment and protection of pets Composition which is useful in particular for the treatment and protection of domestic animals which are infested with parasites or are likely to be infested with them, these compositions comprising, in the form of a ready-to-use solution: a) an insectici... | 05/28/2002 |
| 6117858 | Compositions and methods for altering the biodistribution of biological agents The invention relates to a new and improved pharmaceutical composition and method for delivery of therapeutic agents. The methods and composition of the invention can be used with several therapeutic agents and can achieve site specific delivery of a ther... | 09/12/2000 |
| 6100245 | Use of simethicone to treat ulcerative colitis The present invention provides compositions and methods for treating ulcerative colitis by providing an effective amount of simethicone and in a preferred embodiment in combination with sulfasalazine.... | 08/08/2000 |
| 6004948 | Derivatives of benzosulphonamides as inhibitors of the enzyme cyclooxygenase II Compounds of the formula (I) in which A is oxygen, sulphur or NH; B is a group of the formula (IIa) or (IIb); and the other variables have the meaning given in claim 1, may be used as inhibitors of the enzyme cyclooxygenase II ##STR1##... | 12/21/1999 |
| 5849727 | Compositions and methods for altering the biodistribution of biological agents This invention relates to a new and improved pharmaceutical composition and method for delivery of therapeutic or bioactive agents. The methods and composition of the invention can be used with several therapeutic or bioactive agents and can achieve site-... | 12/15/1998 |
| 5179127 | Halopropargyl acyl compound, compositions, microbicidal uses and processes of preparation Compounds of the formula ##STR1## wherein A is selected from the group consisting of (1) phenyl, (2) naphthyl, (3) phenyl substituted with one or more halo, cyano, (C1 -C4)alkyl, nitro, (C1 -C4)haloalkyl, a... | 01/12/1993 |
| 5110808 | Amide derivatives, compositions and use The invention concerns novel (oxamido- and ureido-phenylsulfonyl)nitromethane derivatives and pharmaceutically acceptable salts thereof which are inhibitors of the enzyme aldose reductase and are of value, for example, in the treatment of certain per... | 05/05/1992 |
| 5041436 | 1-arylsulphonyl-2-piperidinone derivatives, process and intermediates for the preparation thereof, their application as antispasmodics and compositions containing them The invention relates to the products of formula ##STR1## in which R represents the radical ##STR2## in which R1 at any position on the benzene ring represents linear, branched or cyclic alkyl, alkenyl or alkynyl containing up to 8 ca... | 08/20/1991 |
| 5037822 | 1-arylsulphonyl-2-pyrrolidinethione or 1-arylsulphonyl-2-piperidinethione derivatives, process for the preparation thereof their application as medicinal products and compositions containing them The invention relates to the products of formula ##STR1## in which R represents the radical ##STR2## in which R1 at any position on the benzene ring represents a linear, branched or cyclic alkyl, alkenyl or alkynyl containing up to 8 ... | 08/06/1991 |
| 4904647 | Antimicrobial pharmaceutical composition The invention relates to a synergistic, antimicrobial pharmaceutical composition containing 0.01 to 50% by weight of a quinolinecarboxylic acid derivative or a naphthyridinecarboxylic acid derivative of the formula (I), ##STR1## wherein X is car... | 02/27/1990 |
| 4818753 | Synthesis and method of use for 2, 4 diaminoquinazoline Compounds of the formula ##STR1## wherein R1 is H, methyl, ethyl, or chloro and R2 is hydrocarbyl of 1-12 C are useful as antifungal agents. Compounds of this series wherein R2 is 7-12 C are novel. A new synthetic met... | 04/04/1989 |
| 4769447 | Gamma-Glutamyl-4-azoanilides The present invention provides gamma-glutamyl-4-azoanilides, processes for their preparation and their use as substrates for gamma-glutamyl transferase determination, of the formula ##STR1## wherein X is alkyl, --(CH2)m --COOH o... | 09/06/1988 |
| 4742069 | Sulfonamide containing dihydropyridine derivatives, intermediates and medicinal use Dihydropyridine derivatives of the formula ##STR1## wherein the symbols A, R and R1, R2, R3, R4, R5, R6 and R7 are as described herein. Compounds of formula I have a pronounced c... | 05/03/1988 |
| 4735959 | Carboxylic acid amides and pharmaceutical compositions containing them There are described novel carboxylic acid derivatives of the formula ##STR1## and derivatives of the formula ##STR2## and the addition salts thereof, which exhibit an effect on the intermediary metabolism. Furthermore, the compounds of Formula I... | 04/05/1988 |
| 4657903 | Transition metal complexes of the selenium analogs of 2-acetyl- and 2-propionylpyridine thiosemicarbazones useful for treating malarial infections and leukemia This invention relates to novel transition metal complexes of 2-acetyl- and -propionylpyridine thiosemicarbazones, their selenium analogs. These compounds are useful as antimalarial and antileukemic agents. Also disclosed are several synthetic procedures u... | 04/14/1987 |
| 4520131 | Antihypertensive N-substituted 1,4-dihydropyridines Antihypertensive compounds of the formula ##STR1## where the substituents are as herein defined and where Z is alkylene, R3 is alkoxyalkyl and R4 is hydroxyalkyl.... | 05/28/1985 |
| 4415574 | Soluble N2 substituted derivatives of 2,4-diamino 5-benzyl pyrimidine, process for their preparation and medicaments containing them The present invention relates to novel soluble N2 substituted derivatives of 2,4-diamino 5-benzyl pyrimidines. These derivatives correspond to the general formula III below: ##STR1## The novel soluble N2 substituted derivatives ... | 11/15/1983 |
| 4393057 | Pharmaceutical preparations Pharmaceutical preparations containing glycerol alkyl ethers as the solvent.... | 07/12/1983 |
| 4386084 | N-Pyrimidinyl-carbamic acid esters, their preparation, and drugs containing these compounds 2-Carbamic acid esters of 2,4-diamino-5-(3',4',5'-trimethoxybenzyl)-pyrimidine (trimethoprim), a process for their preparation, and drugs containing these compounds, which, as pro-drugs of trimethoprim, have valuable antibacterial properties and pote... | 05/31/1983 |
| 4348389 | Quinoxaline adducts useful as anthelmintics Control of parasitic worm (helminth) infestations in warm-blooded animals including poultry, swine, cattle, sheep and goats by administering substituted quinoxaline adducts to infested animals. In particular, certain adducts of quinoxaline-1,4-dioxides ar... | 09/07/1982 |
| 4315931 | N-Pyrimidinyl-imidoacid esters and drugs containing the said compounds Unsubstituted or substituted 5-phenyl- and 5-benzyl-4-amino-pyrimidine-2-imidoacid esters, their preparation, drugs containing these compounds, and their use in infectious diseases.... | 02/16/1982 |
| 4211776 | N-Substituted 2-methoxybenzenesulphonamides, process for preparing them and medicaments containing them The invention relates to new N-substituted benzenesulphonamides of general formula ##STR1## in which n is 2 or 3, R1 and R2 are hydrogen atoms, methyl, ethyl groups, or jointly form with the nitrogen a nitrogenized heterocyclic ... | 07/08/1980 |
| 4209513 | Tablet formulation A tablet suitable for use in the treatment of microbial infections, which tablet comprises from 80 to 98% (w/w) of a combination of a 2,4-diaminopyrimidine with a sulphonamide and not more than 20% (w/w) of both a granulating and a disintegrating agent, t... | 06/24/1980 |
| 4203980 | Benzylpyrimidine derivatives Benzylpyrimidines of the formula ##STR1## wherein R1 and R2, independently, are C1-6 -alkyl, R3 is C1-3 -alkyl and R4 is methylene or C2-4 -alkylidene and physiologically compati... | 05/20/1980 |
| 4191758 | Benzylpyrimidines Benzylpyrimidines of the formula ##STR1## wherein R1 and R2, independently, are C1-3 -alkyl, and R3 and R4, independently, are hydrogen or methyl, and physiologically acceptable acid addition salts th... | 03/04/1980 |
| 4180578 | 2,4-Diamino-5-(4'-methylthio)benzylpyrimidenes, compounds, compositions and method of use A compound selected from a 2,4-diamino-5-thiobenzylpyrimidine of the formula: ##STR1## in which R is selected from hydrogen, alkyl, lower alkoxy, and halogen and R' is alkyl; and pharmacologically acceptable acid addition salts thereof. These co... | 12/25/1979 |
| 4132786 | N-Substituted 2-methoxybenzenesulphonamides and medicaments containing them The invention relates to new N-substituted benzenesulphonamides of general formula ##STR1## in which N IS 2 OR 3, R1 and R2 are hydrogen atoms, methyl, ethyl groups, or jointly form with the nitrogen a nitrogenized heterocyclic ... | 01/02/1979 |
