Did You Know...
...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Number | Title | Issue Date |
| 7205337 | End-capped polymers and compositions containing such compounds End-capped polymers, methods for making those end-capped polymers, compositions containing those end-capped polymers, and methods for using those compositions are disclosed. One of the disclosed end-capped copolymers has the formula (I): | 04/17/2007 |
| 6773717 | Process and apparatus for the preparation of chlortetracycline-containing animal feed compositions The present invention provides improved chlortetracycline-containing animal feed compositions and processes and apparatuses for their preparation. In certain embodiments, raw fermentation broth comprising chlortetracycline is divided into two portions. The first por... | 08/10/2004 |
| 6429204 | Method of inhibiting cancer growth The invention is a method of inhibiting a sarcoma, such as Kaposi's sarcoma, in a mammal. The method employs 6-demethyl-6-deoxy-4-de(dimethylamino)tetracycline (CMT-3.)... | 08/06/2002 |
| 6310053 | Long-acting oxytetracycline composition An injectable composition is described having a higher residual effect with reduced detrimental effects such as pain at injection site, swelling, tissue irritancy or necrosis. The composition contains as active principle a tetracycline compound, either as... | 10/30/2001 |
| 6277829 | Process for preparing of aqueous formulation for opthalmic use The present invention describes a process for the preparation of aqueous formulations containing azithromycin for ophthalmic use, as well any formulations obtained by this process and their topical use in the ocular bacterial infections, more preferably i... | 08/21/2001 |
| 6191124 | Methanol derivatives for treatment of retroviral infections especially HIV infections The present invention relates to compounds of formula (I) which are imidazo[2,1-b]benzothiazole-3-methanol and imidazo[2,1-b]thiazole-5-methanol derivatives useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus, wherein ... | 02/20/2001 |
| 6110905 | Long-acting oxytetracycline composition An injectable composition of higher residual effect with reduced detrimental effects such as pain at injection site, swelling, tissue irritancy or necrosis and containing as active principle a tetracycline compound, either as the free base or a salt there... | 08/29/2000 |
| 6100248 | Method of inhibiting cancer growth The invention is a method of inhibiting cancer growth, by inhibiting cellular proliferation, invasiveness, or metastasis, or by inducing cytotoxicity against cancer in mammals. The method employs 6-demethyl-6-deoxy-4-de(dimethylamino)tetracycline (CMT-3) ... | 08/08/2000 |
| 5998390 | Combination of bisphosphonate and tetracycline Tissue-destructive conditions related to excess proteinase activity in a biological system are treated or prevented by administering to the system a composition which combines a tetracycline and a bisphosphonate in synergistic proteinase inhibiting amount... | 12/07/1999 |
| 5883074 | Potentiators of antibacterial agents Methods for screening for compounds which potentiate the activity of antibacterial agents against bacteria resistant to the antibacterial agent alone, pharmaceutical compositions including such potentiators, and methods of treating bacterial infections us... | 03/16/1999 |
| 5837696 | Method of inhibiting cancer growth The invention is a method of inhibiting cancer growth, including cellular proliferation, invasiveness, or metastasis in mammals. The method employs 6-demethyl-6-deoxy-4-dedimethylaminotetracycline (CMT-3) and other functionally related chemically modified... | 11/17/1998 |
| 5824666 | Low PH, hydrolytically stable, cosmetic compositions containing acidic actives The present invention relates to leave on, oil-in-water, skin care compositions, comprising: (A) from about 0.05% to about 20% of an acidic active ingredient, preferably having a solubility parameter from about 6 to about 12; (B) from about 0.1% to about ... | 10/20/1998 |
| 5753636 | Injection solution for intramuscular and subcutaneous administration to animals An injection solution for subcutaneous or intramuscular administration to an animal, and a method of producing same, are provided. The injection solution is substantially free of chloride ions and employs a basic amino acid as a pH-adjusting agent, charac... | 05/19/1998 |
| 5604208 | Antibiotic preparation and use of the same in plants An antibiotic formulation comprising gentamicin, and optionally tetracycline or oxytetracycline, for use in plants.... | 02/18/1997 |
| 5312813 | Biofilm reduction method A method of killing microorganisms which form a biofilm on a tissue or implant surfaces in a patient, and which are refractory to a biocide at a dose which is effective to kill the microorganism in planktonic form. The effect of the biocide is potentiated... | 05/17/1994 |
| 5075295 | Novel oxytetracycline compositions Novel aqueous oxytetracycline compositions comprising oxytetracycline, polyethylene glycol with a mean molecular weight of 400, and magnesium oxide. These compositions have good clarity and low viscosity.... | 12/24/1991 |
| 4772460 | Method of reducing the swelling or pain associated with antibiotics compositions Oxytetracycline aqueous solutions, particularly for parenteral administration containing N-Methylpyrollidone as a solvent are disclosed.... | 09/20/1988 |
| 4693997 | Novel pharmaceutical composition A novel complex of carrageenan and a member of the group consisting of emepronium, doxycycline, and propranolol, pharmaceutical preparations containing such a complex, and its use in medicine.... | 09/15/1987 |
| 4608380 | Substituted aminopyridones having histamine H2 -receptor blocking activity This invention relates to 2-substituted aminopyridone compounds which have histamine H2 -antagonist activity.... | 08/26/1986 |
| 4560553 | Use of eucalyptol for enhancing skin permeation of bio-affecting agents Eucalyptol is used to enhance skin permeation of bio-affecting agents.... | 12/24/1985 |
| 4386083 | Injectable oxytetracycline compositions Increased content of oxytetracycline injectable compositions containing glycerol formal as the solvent is achieved by utilization of particular magnesium compounds, viz., magnesium acetate and magnesium chloride. Magnesium chloride is utilized with oxytet... | 05/31/1983 |
| 4376118 | Stable nonaqueous solution of tetracycline salt Nonaqueous solution of a tetracycline antibiotic salt which is stable upon extended storage comprises a mixture of a tetracycline antibiotic salt, nonaqueous diluent, nonaqueous solvent, and nonaqueous nonionic solubilizer. It preferably also contains an ... | 03/08/1983 |
| 4038388 | Antimicrobial compositions The stability of tetracycline is improved by compounding it with 8 - hydroxyquinoline or a chlorinated and/or alkyl derivative thereof. In the compositions, which are particularly suitable for topical application, the tetracycline and the quinoline deriva... | 07/26/1977 |
| 4020162 | Oxytetracycline solution for parenteral, peroral and local administration and processes for the production thereof The present invention relates to an aqueous oxytetracycline solution for parenteral, peroral and local administration, which contains, in addition to the active substance present as base or as salt, polyethylene glycol having a mean molecular weight of 30... | 04/26/1977 |
| 4011313 | Medicament preparations A pharmaceutical preparation having a minor amount of a tetracycline medicament, and a major amount of a dialkylated mono- or poly-alkylene glycol vehicle therefor, and, optionally, a minor amount of one or more antioxidants for the dialkylated glycol veh... | 03/08/1977 |
| 3957980 | Doxycycline parenteral compositions Doxycycline compositions suitable for the preparation of injectable liquid preparations are disclosed.... | 05/18/1976 |
| 3944668 | Antimicrobial compositions The stability of tetracycline is improved by compounding it with 8 - hydroxyquinoline or a chlorinated and/or alkyl derivative thereof. In the compositions, which are particularly suitable for topical application, the tetracycline and the quinoline deriva... | 03/16/1976 |
