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| Number | Title | Issue Date |
| 7629333 | Stable amorphous amifostine compositions and methods for the preparation and use of same The present invention relates to a sterile, stable dosage forms suitable for reconstitution and parenteral administration to a patient, said dosage form comprising an amorphous aminoalkyl dihydrogen phosphorothioate, and of amifostine in particular. The invention fu... | 12/08/2009 |
| 7244718 | Water soluble prodrugs of hindered alcohols The present invention is directed to novel water-soluble prodrugs of aliphatic or aromatic hindered hydroxyl group containing pharmaceuticals. ... | 07/17/2007 |
| 7176185 | Short peptide carrier system for cellular delivery of agent A dipeptide or tripeptide carrier system for active agent delivery to cells has an N-terminus natural amino acid and an active agent covalently bonded to a side chain of one of the remaining amino acid bases. The system is amenable to formulation as an oral administ... | 02/13/2007 |
| 7163918 | Iodothyronine compositions The present invention relates to compositions comprising thyroxine (T4) and triiodothyronine (T3). More specifically, the invention relates to thyroxine (T4) and triiodothyronine (T3) compositions that include a peptide carrier and thyroxine (T4) and triiodothyronin... | 01/16/2007 |
| 7109181 | Joint lubrication with P2Y purinergic receptor agonists The present invention is directed to a method of altering the amount or composition of synovial fluids secreted from joints in a subject in need of such treatment. The method comprises administering to a subject a pharmaceutical composition comprising a P2Y purinerg... | 09/19/2006 |
| 7078552 | Combretastatin A-1 phosphate and combretastatin B-1 phosphate prodrugs The present invention relates to the syntheses and structural elucidation of Combretastatin A1-Phosphate Prodrugs and Combretastatin B1-Phosphate Prodrugs and the utilization of those prodrugs in the treatment of neoplastic diseases. The prodrugs described herein ha... | 07/18/2006 |
| 7060708 | Active agent delivery systems and methods for protecting and administering active agents The present invention relates to active agent delivery systems and more specifically to compositions that comprise amino acids, as single amino acids or peptides, covalently attached to active agents and methods for administering conjugated active agent compositions... | 06/13/2006 |
| 7041658 | Method of inhibiting hair growth Disclosed herein are a method of inhibiting hair growth, which comprises administering an inhibitor of elastase-like enzymes or a neutral endopeptidase inhibitor, and use of an inhibitor of elastase-like enzymes or a neutral endopeptidase inhibitor for the preparati... | 05/09/2006 |
| 6943155 | Unique compositions of zwitterionic phospholipids and bisphosphonates and use of the compositions as bisphosphate delivery systems with reduced GI toxicity Compositions and methods for treating osteoporosis using the compositions are disclosed where the compositions have reduced GI toxicity and improved bio-availability and include a bisphosphonate and zwitterionic phospholipid. ... | 09/13/2005 |
| 6923989 | Method for preparing a calcium phosphate pasty material for injection A method for preparing a calcium phosphate pasty material for injection which after, setting, is designed to form an apatite material consists in: producing from water and calcium phosphates pasty mixture capable of developing, hardening and forming a hydroxyapatite... | 08/02/2005 |
| 6841545 | Stable amorphous amifostine compositions and methods for the preparation of same The present invention relates to a sterile, stable dosage forms suitable for reconstitution and parenteral administration to a patient, said dosage form comprising an amorphous aminoalkyl dihydrogen phosphorothioate, and of amifostine in particular. The invention fu... | 01/11/2005 |
| 6803057 | Hydrogen peroxide disinfectant with increased activity An acidic aqueous hydrogen peroxide solution is provided with improved disinfectant activity. Concentrated solutions preferably contain up to about 8 wt./wt. % H2O2 and as-used concentrations contain about 0.5% wt./wt. % H2O2. The solution also contains from 0.05 to... | 10/12/2004 |
| 6776977 | Polypodal chelants for metallopharmaceuticals Tripodal polyaminophosphonate chelants are disclosed, as well as chelates of the chelants with metal ions to form radiopharmaceutical and radioactive, MRI and X-ray or CT imaging compounds and compositions. Therapeutic and imaging methods of use are also disclosed. | 08/17/2004 |
| 6747017 | Method of inhibiting hair growth Disclosed herein are a method of inhibiting hair growth, which comprises administering an inhibitor of elastase-like enzymes or a neutral endopeptidase inhibitor, and use of an inhibitor of elastase-like enzymes or a neutral endopeptidase inhibitor for the preparati... | 06/08/2004 |
| 6649646 | Insecticidal and miticidal compositions The invention relates to an insecticidal and miticidal composition which contains as active ingredients chlorfenapyr in combination with one or more organophosphoric acid ester-type compounds and to a method for controlling insecticidal or miticidal pests... | 11/18/2003 |
| 6566304 | Biogenic control and limitation of the reproduction of parasitic earth nematodes in stock culture The invention relates to use of (a) compounds of phosphorus containing at least partly lipophilic organic radicals together with (b) urea and/or urea derivatives in selected quantity ratios of (a) to (b) as a soil additive for biologically controlling pla... | 05/20/2003 |
| 6562845 | Materials and methods for the control of tephritidae fruit flies The subject invention provides materials and methods for the effective control of fruit flies. Specifically, the subject invention pertains to the use of imidacloprid compounds to control fruit flies. These compounds achieve a high level of control withou... | 05/13/2003 |
| 6525035 | Therapeutic composition and methods The invention provides composition comprising, 1) polyprenol monophosphates of the formula H--[--CH2-C(CH3).dbd.CH--CH2]n-O--P(.dbd.O)(OH)2 wherein n is an integer from 6-19 inclusive or a salt thereof, and 2) polyprenol pyrophosphates of the formula H--[... | 02/25/2003 |
| 6521264 | Method for preparing a biomaterial based on hydroxyapatite, resulting biomaterial and surgical or dental use A solid powder product with a Ca/P ratio of between 1.40 and 1.90 is prepared from tricalcium phosphate and tetracalcium phosphate. An aqueous solution containing calcium ions and phosphate ions with a Ca/P ratio higher than 0.20 and lower than 0.50 is pr... | 02/18/2003 |
| 6458775 | NAALADase inhibitors useful as pharmaceutical compounds and compositions The present invention relates to N-Acetylated -Linked Acidic Dipeptidase (NAALADase) inhibitors enzyme activity, pharmaceutical compositions comprising such inhibitors, and methods of their use to inhibit NAALADase enzyme activity, thereby effectin... | 10/01/2002 |
| 6413949 | Prodrugs with enhanced penetration into cells The invention relates to a pharmaceutically acceptable prodrug which is a covalent conjugate of a pharmacologically active compound and an intracellular transporting adjuvant, characterized by the presence of a covalent bond which is scission-sensitive to... | 07/02/2002 |
| 6410522 | Anti-depressant, stress suppressor and mood improver An anti-depressant, mental & emotional stress suppressor and mood improver having a prominent action for decreasing blood cortisol level and serotonin reuptake and has an effect of alleviating symptoms associated with depression and mental & emotional str... | 06/25/2002 |
| 6391328 | Controlled delivery compositions and processes for treating organisms in a column of water on land Controlled release compositions of matter are disclosed comprising complexes for treating a population of ore or more aquatic organisms in a column of water. The complexes comprise a least one system wherein the system comprises at least one bioactive age... | 05/21/2002 |
| 6387386 | Controlled delivery compositions and processes for treating organisms in a column of water or on land Controlled release compositions of matter are disclosed comprising complexes for treating a population of one or more aquatic organisms in a column of water. The complexes comprise at least one system wherein the system comprises at least one bioactive ag... | 05/14/2002 |
| 6380177 | LPA analogs as agonists of the Edg2 LPA receptor Applicant has probed the Edg2 lysophosphatidic acid (LPA) receptor with a series of LPA analogs to determine receptor activation. The present invention is drawn to a series of LPA analogs which function as Edg2 receptor agonists, and methods of using such... | 04/30/2002 |
| 6369045 | Phospholipase A2 inhibitors thereof and use of same in diagnosis and therapy The enzyme Lp-PLA2 in purified form, an isolated nucleic acid molecule incoding Lp-PLA2, the use of an inhibitor of the enzyme Lp-PLA2 in therapy and a method of screening compounds to identify those compounds which inhibi... | 04/09/2002 |
| 6355629 | Prodrugs with enhanced penetration into cells The invention relates to a pharmaceutically acceptable prodrug which is a covalent conjugate of a pharmacologically active compound and an intracellular transporting adjuvant, characterized by the presence of a covalent bond which is scission-sensitive to... | 03/12/2002 |
| 6338860 | Compositions for plants containing phosphonate and phosphate salts, and derivatives thereof A fungicidal composition for plants containing phosphonate (PO3) and phosphate (PO4) salts, and derivatives thereof is disclosed. The composition provides a single product which may be employed to control a Phytophthora infestans inf... | 01/15/2002 |
| 6313106 | Phospholipid derivatives of valproic acid and mixtures thereof The present invention relates to compounds, which are phospholipid derivatives of valproic acid, to compositions comprising said compounds and their use for treating epilepsy, migraine, bipolar disorders and pain.... | 11/06/2001 |
| 6245761 | Indolyl neuropeptide Y receptor antagonists This invention provides a series of substituted indoles which are useful in treating or preventing a condition associated with an excess of neuropeptide Y. This invention also provides the novel substituted indoles as well as pharmaceutical formulations w... | 06/12/2001 |
| 6200961 | Concentrates of organophosphorous insecticides A low volatile organic compound co-solvent system is disclosed for preparing emulsion concentrates of low melting organophosphorous insecticides wherein the bioefficacy of the insecticide active is significantly enhanced. The co-solvent system comprises a... | 03/13/2001 |
| 6197777 | Synthesis, anti-human immunodeficiency virus, and anti-hepatitis B virus activities of 1,3-oxaselenolane nucleosides A method and composition for the treatment of HIV infection, HBV infection, or abnormal cellular proliferation in humans and other host animals is disclosed that includes the administration of an effective amount of a 1,3-oxaselenolane nucleoside or a pha... | 03/06/2001 |
| 6172119 | Method of treating acute renal failure This invention relates to a method of treating patients afflicted with acute renal failure. The method includes administering to a patient in need of treatment an effective amount of a thiol or reducible disulfide compound according to the formula set for... | 01/09/2001 |
| 6165997 | Phospholipids having antimicrobial activity with or without the presence of antimicrobials A pharmaceutical formulation for stimulating growth of Gram-positive Bacilli and increasing the acidity in vagina comprises sucrose and/or maltose, optionally with other sugars, viscous base, and anti-fungal and/or anti-bacterial agents.... | 12/26/2000 |
| 6127465 | Polycarbonate resin composition Disclosed is a polycarbonate resin composition comprising an aromatic polycarbonate (PC), a high-impact polystyrene resin (HIPS) and a non-halogen phosphate, and also talc and/or polytetrafluoroethylene (PTFE). Optionally, the composition may contain a co... | 10/03/2000 |
| 6123966 | Stabilized two-part disinfecting system and compositions and methods related thereto A stabilized two-part disinfecting system comprising a first part and a second part adapted to be mixed to yield an aqueous disinfecting composition. The first part contains a non-esterifying acid and an alcohol-containing humectant or antifreeze, while t... | 09/26/2000 |
| 6077838 | Method of treating hangover This invention relates to a method of treating patients afflicted with hangover. The method includes administering to a patient in need of treatment an effective amount of a thiol or reducible disulfide compound according to the formula set forth in the s... | 06/20/2000 |
| 6077837 | Prodrugs with enhanced penetration into cells The invention relates to a pharmaceutically acceptable prodrug which is a covalent conjugate of a pharmacologically active compound and an intracellular transporting adjuvant, characterized by the presence of a covalent bond which is scission-sensitive to... | 06/20/2000 |
| 5997910 | Plant fertilizer compositions containing phosphonate and phosphate salts and derivatives thereof A fertilizer composition for plants containing phosphonate and phosphate slats, and derivatives thereof is disclosed. The composition provides a single product which may be employed to stimulate the growth response in plants.... | 12/07/1999 |
| 5977090 | Pharmaceutical compositions and methods of treating compulsive disorders using NAALADase inhibitors The present invention relates to a pharmaceutical composition and a method for treating a compulsive disorder using a NAALADase inhibitor.... | 11/02/1999 |
