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| Number | Title | Issue Date |
| 7517869 | Fluorophosphonocinnamic compounds, synthesis and uses for treating disorders caused by oxidative stress Process for the specific fluorination of the phosphorus atom of a phosphonocinnamic compound of the general formula (II) or (II′): X being selected from: an oxygen atom, a sulfur atom, R1, R | 04/14/2009 |
| 7371905 | Method of producing hydrofluorocarbons A process for producing fluorinated C1 HFCs comprising fluorinating a reactive organic compound to produce a reaction product comprising at least the desired C1 HFC, unreacted reactive organic compound and a byproduct having a boiling point between the boiling point... | 05/13/2008 |
| 7335470 | Compilations of nucleic acids and arrays and methods of using them In one aspect the invention provides compilations of nucleic acids, articles of manufacture, e.g., arrays, and methods for the detection of chromosomal abnormalities, such as a chromosomal aneuploidies, deletions, amplifications, and the like, and the diagnosis or p... | 02/26/2008 |
| 7189311 | Purification of difluoromethane A method for separating difluoromethane from a mixture of difluoromethane and at least one impurity, the method involving extractively distilling the mixture using dichloromethane as an extractive agent to recover a product stream of purified difluoromethane having ... | 03/13/2007 |
| 7084126 | Methods and compositions for enhancing cellular function through protection of tissue components Methods and composisions for enhancing cellular function through protection of a tissue components such receptors, proteins, lipids, nucleic acids, carbohydrates, hormones, vitamins, and cofactors, by administering pyrophosphate analogs or related compounds. ... | 08/01/2006 |
| 7015209 | Hair-growing agent A hair-growing agent comprising, as active ingredients, one or more members selected from the group consisting of lysophosphatidic acids, and phosphatidic acids wherein the fatty acid residue moiety consists only of straight-chain fatty acid residues having an even ... | 03/21/2006 |
| 6919322 | Phenyl Phosphonate Fructose-1,6-Bisphosphatase Inhibitors Novel FBPase inhibitors of the formula I are useful in the treatment of diabetes and other conditions associated with elevated blood glucose. ... | 07/19/2005 |
| 6762183 | Active substance combinations having insecticidal and acaricidal properties The invention relates to novel active compound combinations of certain cyclic ketoenols and certain active compounds that together have unexpectedly good insecticidal and acaricidal properties. ... | 07/13/2004 |
| 6566304 | Biogenic control and limitation of the reproduction of parasitic earth nematodes in stock culture The invention relates to use of (a) compounds of phosphorus containing at least partly lipophilic organic radicals together with (b) urea and/or urea derivatives in selected quantity ratios of (a) to (b) as a soil additive for biologically controlling pla... | 05/20/2003 |
| 6562803 | Hair-growing agent The present invention provides a hair-growing agent comprising, as an active ingredient, a phosphatidic acid represented by formula (I): ##STR1## (wherein R1 represents straight-chain alkyl having an odd number of carbon atoms, straight-chain a... | 05/13/2003 |
| 6562804 | Hair-growing agent The present invention provides a hair-growing agent comprising, as an active ingredient, a phosphatidic acid represented by formula (I): ##STR1## (wherein R1 represents alkyl, alkenyl, alkanoyl or alkenoyl; and when R1 represents alk... | 05/13/2003 |
| 6525035 | Therapeutic composition and methods The invention provides composition comprising, 1) polyprenol monophosphates of the formula H--[--CH2-C(CH3).dbd.CH--CH2]n-O--P(.dbd.O)(OH)2 wherein n is an integer from 6-19 inclusive or a salt thereof, and 2) polyprenol pyrophosphates of the formula H--[... | 02/25/2003 |
| 6506737 | Antimicrobial phosphonium and sulfonium polyhalide compositions An oxidizing species is described herein as a reaction product through an in situ preparation combining a protonizable phosphorus or sulfur compound, and a halide source at controlled proportions in an aqueous, non-aqueous, gel, aerosol, solid-phase or po... | 01/14/2003 |
| 6365580 | Process for the production of difluoromethane The present invention provides a vapor phase process for the production of difluoromethane, HFC-32. The process of this invention provides for the preparation of HFC-32 by a process that exhibits both good product yield and selectivity.... | 04/02/2002 |
| 6242433 | Geranylgeranyl-derivatives, process for the preparation thereof and related pharmaceutical compositions The present invention relates to novel geranylgeranyl derivatives and the pharmaceutically acceptable salts thereof having antiproliferative activity in eukaryotic cells with respect to the inhibition of protein geranygeranylation. The invention also rela... | 06/05/2001 |
| 6184214 | Pharmaceutical formulations A pharmaceutical composition is provided comprising an effective amount of a phosphoenolpyruvate compound of the formula: ##STR1## wherein R1 and R2 are independently H, alky, alkenyl, alkoxy (except where applied to OR1),... | 02/06/2001 |
| 6096330 | Alkylphosphines as pesticidal agents A method for controlling pests comprising administering to them a compound of the formula (i) R-PH-R', wherein R is a C1 -C6 aliphatic hydrocarbyl group and R' is H or a C1 -C6 aliphatic hydrocarbyl group. Eithe... | 08/01/2000 |
| 5846955 | Acylated phospholipid drugs This invention relates to a method for improving the efficiency of a drug containing a free carboxy group, the improvement comprising esterifying said carboxy group to the hydroxy group of the glycerol portion of a glycerolphospholipid ester having the fo... | 12/08/1998 |
| 5709890 | Polyaspartic acid and its analogues in combination with insecticides An insecticide composition is enhanced from the standpoint of its ability to be absorbed by insects, such as red fire ants, particularly dithiophosphate ester pesticides by the addition of a small amount of a water soluble non-aromatic polyorganic acid or... | 01/20/1998 |
| 5648349 | PLA2 inhibitors PLA2 inhibitors selected from the group consisting of ##STR1## wherein A is selected from the group consisting of ##STR2## and Z, W, R1, R2, R3, R4, R5, R6, R7, ... | 07/15/1997 |
| 5646133 | Polyaspartic acid and its analogues in combination with insecticides An insecticide composition is enhanced from the standpoint of its ability to be absorbed by insects, such as red fire ants, particularly dithiophosphate ester pesticides by the addition of a small amount of a water soluble non-aromatic polyorganic acid or... | 07/08/1997 |
| 5639653 | Method for proliferating Vγ2Vδ2 T cells This invention is directed to a method for stimulating the proliferation of Vγ2Vδ2 T cells comprising contacting Vγ2Vδ2 T cells with a Vγ2Vδ2 T cell proliferation stimulating amount of a compound selected from the group consisting of a monoalkyl pho... | 06/17/1997 |
| 5627174 | Fluoroalkenyl compounds and their use as pest control agents Fluorinated alkene compounds useful for and methods of controlling nematodes, insects, and acarids that prey on agricultural crops, these compounds having the general structure: ##STR1## These Polar compounds are particularly useful for systemic cont... | 05/06/1997 |
| 5574025 | Inhibitors of prenyl-protein transferases The compounds disclosed inhibit the prenylation of several proteins. These compounds are potent inhibitors of famesyl-protein transferase and geranylgeranyl-protein transferase. Further contained in this invention are chemotherapeutic compositions contain... | 11/12/1996 |
| 5541221 | Pharmaceutical compositions and method for administering 3 and 4-substituted 2(5H)-furanones to a mammal for inhibiting bone loss 3 and 4-substituted 2(5H)-furanone compounds influence the balance between bone production and bone resorption in mammals, including humans. The active compounds are administered to mammals, including humans, in an effective dose which ranges between 0.05... | 07/30/1996 |
| 5532226 | Trifluoromethybenzylphosphonates useful in treating osteoporosis Novel benzylphosphonate compounds of the general formula I: ##STR1## are disclosed as useful in treating bone wasting diseases including postmenopausal osteoporosis in increasing in mammals bone formation and bone mass.... | 07/02/1996 |
| 5480877 | Use of lysophosphatidic acids to enhance fibronectin binding Lysophosphatidic acids are used to enhance fibronectin binding. This assists in the process of wound healing. The acids are exogenously supplied. In one aspect, a kit is provided containing a skin salve that contains the acid or a salt thereof.... | 01/02/1996 |
| 5366727 | Antibacterial agent An antibacterial agent comprising as an active ingredient a vinylbenzyl phosphonium salt of the general formula (I), ##STR1## wherein R1, R2 and R3 each represent a hydrogen atom, a linear or branched alkyl group havi... | 11/22/1994 |
| 5306714 | (S)-2,3-dihydropolyprenyl, monophosphate, and agents for inhibiting the metastasis of cancers Disclosed are (S)-2,3-dihydropolyprenol of formula (I) ##STR1## wherein m is 7 or 8 and (S)-2,3-dihydropolyprenyl monophosphate of formula (II) ##STR2## wherein m is 7 or 8 as well as pharmaceutically acceptable salts thereof. They are usef... | 04/26/1994 |
| 5242908 | Use of benzylphosphonic acid derivatives for the treatment of diseases caused by viruses The use of a compound of the formula I ##STR1## in which V is an alkyl group, fluorine, chlorine, bromine, or iodine, n is an integer from 1 to 5, W is an alkyl, alkenyl, alkynyl or alkoxy group, cyanide, nitro, carboxyl, hydrogen or a cycloalkyl, ar... | 09/07/1993 |
| 5186947 | Wood preservative based on polymeric nitrogen compounds and metal-fixing acids Water-soluble wood preservatives which contain mixtures of a metal compound, a metal-fixing acid and a complexing polymeric nitrogen compound, and methods for protecting wood with such mixtures.... | 02/16/1993 |
| 5147867 | Phosphorus containing enzyme inhibitors Dipeptide mimics which contain phosphorus and their pharmaceutical use and preparation are disclosed. The compounds have dehydropeptidase (DHP) enzyme inhibitor activity.... | 09/15/1992 |
| 5128333 | Alkyl substituted phosphates and phosphonates as disruptants of insect sex pheromone-mediated behavior Compounds of the general formula I ##STR1## wherein R1 represents --R3, --OR3 or --N(R3)2, in which R3 is alkyl of 1 to about 18 carbon atoms; R2 represents alkyl of 1 to about 18 carbon atoms; and X represents --OR3, halogen, --CN, --SR4 or --... | 07/07/1992 |
| 5064820 | Alkyl substituted phosphates and phosphonates as disruptants of insect sex pheromone-mediated behavior Compounds of the general formula I ##STR1## wherein R1 represents --R3, --OR3 or --N(R3)2, in which R3 is alkyl of 1 to about 18 carbon atoms; R2 represents alkyl of 1 to about 18 carbon atoms; and X represents --OR3, halogen, --CN, --SR4 or --... | 11/12/1991 |
| 5015635 | Pesticidal S-(halogenoalkyl)-dithiophosphoric(phosphonic) acid esters Pesticidal S-(halogenoalkyl)-dithiophosphoric (phosphonic) acid esters of the formula ##STR1## in which R1 represents an optionally substituted radical from the group consisting of alkyl, alkenyl, alkoxy, alkenyloxy and alkinyloxy, R2... | 05/14/1991 |
| 5004735 | Pharmaceutical compositions for the inhibition of tumor metastasis Polyprenols and polyprenyl phosphates are of the formula ##STR1## wherein ##STR2## represents a trans-isoprene unit, ##STR3## represents a cis-isoprene unit, ##STR4## represents a dihydroisoprene unit, l is an integer of 2 to 8, m... | 04/02/1991 |
| 4970199 | Steroidal glycolipids as host resistance stimulators against viral infection Disclosed are steroidal derivatives of glycolipids, in which steroids are bridged, via a medium length hydrocarbon chain, to 1-thio-D-mannopyranoses or 1-thio-L-fucopyranoses in combination with an anti-AIDS drug, that protect an immunocomprimised hot, pa... | 11/13/1990 |
| 4962097 | Method of treating bacterial infection with phosphorus containing DHP enzyme inhibitors Dipeptide mimics which contain phosphorus and their pharmaceutical use and preparation are disclosed. The compounds have dehydropeptidase (DHP) enzyme inhibitor activity.... | 10/09/1990 |
| 4946834 | Phosphonic acid substituted steroids as steroid 5-reductase inhibitors Invented are substituted acrylate analogues of steroidal synthetic compounds, pharmaceutical compositions containing the compounds, and methods of using these compounds to inhibit steroid 5-reductase. Also invented are intermediates used in prepari... | 08/07/1990 |
| 4938797 | Process for the preparation of microcapsules The invention relates to a process for the preparation of microcapsules having a capsule wall of polyurea and encapsulating a water-immiscible pesticide. The process comprises first dispersing a solution of a polyisocyanate in the sparingly water-soluble ... | 07/03/1990 |
