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Class 514/129 - Oxygen bonded directly to a carbon or hydrogen and wherein the oxygen is not bonded directly to phosphorus


Subclass of Class 514 - Drug, bio-affecting and body treating compositions
Definition: Subject matter wherein the organo-phosphorus compound contains
No. of patents: 154
Last issue date: 05/04/2010


1        
NumberTitleIssue Date
7709465Phosphorous containing compounds including triphenylmethylphosphonate esters for the treatment of melanoma and other cancers
Compounds and related methods for synthesis, and the use of compounds and combination therapies for the treatment of cancer and modulation of apoptosis in cells are disclosed. Particularly disclosed are phosphonate esters. Compounds, methods of making the compounds,...
05/04/2010
7432253Phosphoepoxides, method for making same and uses
The invention provides compounds comprising at least one phosphoepoxide group of the formula: where R1 is selected from among —CH3 and —CH2—CH3. Cat+...
10/07/2008
7378403Akt inhibitors, pharmaceutical compositions, and uses thereof
Disclosed are inhibitors of the serine/threonine kinase Akt, pharmaceutical compositions comprising such inhibitors, and a method of preventing or treating a disease or condition in an animal by the use of such inhibitors. The Akt inhibitors have the formula (I) whe...
05/27/2008
7371740Phosphorylated glyceryl ether aluminum salt
The present invention relates to a phosphorylated glyceryl ether aluminum salt represented by the general formula (1): (wherein R1 represents an alkyl or an alkenyl group with 8 to 32 carbon atoms; R2 ...
05/13/2008
7335675Aqueous suspension formulation for foliar application fungicide
The present invention provides an aqueous suspension formulation containing (RS)-N-[2-(1,3-dimethylbutyl)thiophene-3-yl]-1-methyl-3-trifluoromethyl-1H-pyrazole-4-carboxamide and having high rain resistance and stable residual effectiveness. A aqueous suspensi...
02/26/2008
7189408Cosmetic compositions
Base compositions (premix) comprising the following components: A) a perfluoropolyether phosphate; B) a solvent; C) water. ...
03/13/2007
7153843Inhibitors of phosphatidyl myo-inositol cycle
The present invention relates to the preparation and biological activity of 3-deoxy-Dmyo-inositol ether lipid analogs as inhibitors of phosphatidylinositol-3-kinase signaling and cancer cell growth. The compounds of the present invention are useful as anti-tumor 5 a...
12/26/2006
7144588Method of preventing surgical adhesions
The present invention relates to a method and composition for preventing surgical adhesions during surgery. Tissue surfaces and/or surgical articles involved in the surgery are separated by a biomaterial provided in the form of a non-crosslinked, decellularized and ...
12/05/2006
7135581Antiangiogenic agents
Compositions and methods for treating mammalian disease characterized by undesirable angiogenesis by administering derivatives of 2-methoxyestradiol of the general formula: wherein the variables are defined in th...
11/14/2006
7115661Methods and compositions for mitigating pain
Methods and therapeutic compounds for treating pain, mitigating inflammation, effecting analgesia and/or effecting sedation in a subject are described. A subject is administered an effective amount of a therapeutic compound which is a nitrate ester. Novel pharmaceut...
10/03/2006
7109183Phosphohalohydrins, process for the production thereof and use thereof
The invention provides compounds comprising at least one phosphohalohydrin group of the formula: where X is a halogen selected from among I, Br, Cl, R1 is selected from among â€...
09/19/2006
7008963Urushiol induced contact dermatitis solution
A solution for urushiol induced contact dermatitis is provided for in a topical solution. According to the invention, a method is provided for applying a composition of substances to the affected area, working the composition into the affected area, and removing the...
03/07/2006
6916835Nitrate esters and their use for neurological conditions
Compounds and methods for mitigating neurodegeneration, effecting neuroprotection and/or effecting cognition enhancement in a subject are described. Neurological or cognitive conditions are treated by administering to a subject an effective amount of a therapeutic c...
07/12/2005
6908909Liquid oral compositions comprising a calcium compound and an acidulant
Acidic oral compositions having reduced tooth erosion characteristics, especially acid beverages such as fruit juice drink concentrates, or oral healthcare products such as mouthwashes, are prepared by adding a calcium compound to the acid composition so that the mo...
06/21/2005
6762183Active substance combinations having insecticidal and acaricidal properties
The invention relates to novel active compound combinations of certain cyclic ketoenols and certain active compounds that together have unexpectedly good insecticidal and acaricidal properties. ...
07/13/2004
6743784Estrogen mimetics lacking reproductive tract effects
A method for treating symptoms, diseases and conditions in extra-reproductive tract tissues that are responsive to treatment with estrogen, using triarylethanes of formula (I) wherein R1 is —O(CH2...
06/01/2004
6727234Isoprenoid analog compounds and methods of making and use thereof
The invention provides compounds of formula I: wherein X, R1, R2, and n have any of the values defined in the specification, and their pharmaceutically acceptable salts. The compounds are useful, fo...
04/27/2004
6699485Cosmetic compositions
Base compositions (premix) comprising the following components: A) a perfluoropolyether phosphate; B) a solvent; C) water....
03/02/2004
6664245Adhesive compositions for hard tissues
An adhesive composition is provided which is suitable for the bonding of polymeric materials, in whole or in part, such as composite resins, or methacrylate-containing glass-ionomer filling materials, to tooth enamel, or tooth dentin, or to other hand tis...
12/16/2003
6649646Insecticidal and miticidal compositions
The invention relates to an insecticidal and miticidal composition which contains as active ingredients chlorfenapyr in combination with one or more organophosphoric acid ester-type compounds and to a method for controlling insecticidal or miticidal pests...
11/18/2003
6645952Adhesive compositions for hard tissues
An adhesive composition is provided which is suitable for the bonding of polymeric materials, in whole or in part, such as composite resins, or methacrylate-containing glass-ionomer filling materials, to tooth enamel, or tooth dentin, or to other hand tis...
11/11/2003
6596711(Aminopropyl)methylphosphinic acids
Novel compounds of formula I, with the exception of i) the racemate of (3-amino-2-hydroxypropyl)methylphosphinic acid; ii) (S)-(3-amino-2-hydroxypropyl)methylphosphinic acid; iii) (R)-(3-amino-2-hydroxypropyl)methylphosphinic acid; iv) (3-amino-2-hydroxypropyl)difluorom...
07/22/2003
6566304Biogenic control and limitation of the reproduction of parasitic earth nematodes in stock culture
The invention relates to use of (a) compounds of phosphorus containing at least partly lipophilic organic radicals together with (b) urea and/or urea derivatives in selected quantity ratios of (a) to (b) as a soil additive for biologically controlling pla...
05/20/2003
6541019Preservatives of formulations for topical use
Use as preservative in formulations for topical use containing water of a component A): a (per)fluoropolyether phosphate of general formula: Rf --[CF2 CH2 --Q--L--P(O) (OZ1) (OZ2)]l (I) wherein l=1 ...
04/01/2003
6521264Method for preparing a biomaterial based on hydroxyapatite, resulting biomaterial and surgical or dental use
A solid powder product with a Ca/P ratio of between 1.40 and 1.90 is prepared from tricalcium phosphate and tetracalcium phosphate. An aqueous solution containing calcium ions and phosphate ions with a Ca/P ratio higher than 0.20 and lower than 0.50 is pr...
02/18/2003
6506737Antimicrobial phosphonium and sulfonium polyhalide compositions
An oxidizing species is described herein as a reaction product through an in situ preparation combining a protonizable phosphorus or sulfur compound, and a halide source at controlled proportions in an aqueous, non-aqueous, gel, aerosol, solid-phase or po...
01/14/2003
6495533Drugs containing phosphoric acid derivatives as the active ingredient
The present invention relates to phosphoric acid derivatives represented by general formula (I), wherein each symbol is as defined in the description and nontoxic salts thereof. Because of having a TNF଱ production inhibitory effect, the compounds re...
12/17/2002
6475527Use of chlorate ion or preparations thereof for reduction of food borne pathogens
The invention provides a method and compositions for controlling food borne enteric bacterial pathogens in animals. Populations of enteropathogenic bacteria may be substantially reduced or eliminated by treatment of animals with an effective amount of the...
11/05/2002
6429203Farnesyl-protein transferase inhibitors
Substantially pure preparations of phosphosesquiterpenes are described. The compounds inhibit farnesyl-protein transferase activity and are useful for the treatment of cancer. Methods for inhibiting farnesyl-protein transferase activity are also described...
08/06/2002
6365579Nitrate esters and their use for neurological conditions
Compounds and methods for mitigating neurodegeneration, effecting neuroprotection and/or effecting cognition enhancement in a subject are described. Neurological or cognitive conditions are treated by administering to a subject an effective amount of a th...
04/02/2002
6338860Compositions for plants containing phosphonate and phosphate salts, and derivatives thereof
A fungicidal composition for plants containing phosphonate (PO3) and phosphate (PO4) salts, and derivatives thereof is disclosed. The composition provides a single product which may be employed to control a Phytophthora infestans inf...
01/15/2002
6323190Estrogen mimetics lacking reproductive tract effects
A method for treating symptoms, diseases and conditions in extra-reproductive tract tissues that are responsive to treatment with estrogen, using triarylethanes of formula (I) ##STR1## wherein R1 is --O(CH2)m R3...
11/27/2001
6310052Nitrate esters and their use for neurological conditions
Compounds and methods for mitigating neurodegeneration, effecting neuroprotection and/or effecting cognition enhancement in a subject are described. Neurological or cognitive conditions are treated by administering to a subject an effective amount of a th...
10/30/2001
6245754Inhibitors of phosphatidyl myo-inositol cycle
The present invention relates to the preparation and biological activity of 3-deoxy-D-myo-inositol ether lipid analogs as inhibitors of phosphatidylinositol-3-kinase signaling and cancer cell growth. The compounds of the present invention are useful as an...
06/12/2001
6242433Geranylgeranyl-derivatives, process for the preparation thereof and related pharmaceutical compositions
The present invention relates to novel geranylgeranyl derivatives and the pharmaceutically acceptable salts thereof having antiproliferative activity in eukaryotic cells with respect to the inhibition of protein geranygeranylation. The invention also rela...
06/05/2001
6200962Thionophosphate derivatives, process for their preparation and pharmaceutical compositions containing them
The invention relates to a compound of formula (I) ##STR1## in which X1 and X2 each independently represents an oxygen or nitrogen atom; p,m and n are each independently an integer of at least 2; R, R1 and R2 ea...
03/13/2001
6200961Concentrates of organophosphorous insecticides
A low volatile organic compound co-solvent system is disclosed for preparing emulsion concentrates of low melting organophosphorous insecticides wherein the bioefficacy of the insecticide active is significantly enhanced. The co-solvent system comprises a...
03/13/2001
6174874Phosphonic acids derivatives as inhibitors of protein tyrosine phosphate 1B (PTP-1B)
The invention encompasses the novel class of compounds represented by formula I which are inhibitors of the PTP-1B enzyme. ##STR1## The invention also encompasses pharmaceutical compositions and methods of treating or preventing PTP-1B mediated diseases....
01/16/2001
6117857Pharmaceutical composition
The invention relates to a pharmaceutical composition comprising an antiviral compound selected from the group consisting of foscarnet, acyclovir, valaciclovir, penciclovir and famciclovir, in admixture with galactolipids and a polar solvent. The pharmace...
09/12/2000
6114340Fungicidal compositions
An improved fungicidal composition is a mixture of (a) fungicide used to combat phytopathogenic fungi and (b) at least one phosphonate or phosphinate of formula R1 R2 P(O)OR3 where R1 is C6-20 alkyl, ...
09/05/2000
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