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| Number | Title | Issue Date |
| 7442671 | O-phenylphenol/alkoxylated amine wood protection compositions A composition for protecting wood from decay, mildew and sapstain comprises o-phenylphenol in combination with an alkoxylated amine, wherein the weight ratio of alkoxylated amine to o-phenylphenol ranges from 1:1 to 10:1. Organic or inorganic acids may be added to e... | 10/28/2008 |
| 7368440 | Methods for the administration of amifostine and related compounds The present invention provides methods of administering amifostine, WR-1065, or a combination thereof, to patients receiving radiation therapy or chemotherapy in a manner that significantly reduces or decreases the adverse or undesirable side-effects of the compound... | 05/06/2008 |
| 7314959 | Amino thiol compounds and compositions for use in conjunction with cancer therapy The invention provides novel polyamine and amino thiol compounds and pharmaceutical compositions for administration in conjunction with cancer chemotherapy or radiation therapy. The compounds are administered locally to provide protection against the adverse side-ef... | 01/01/2008 |
| 7309698 | Compositions for delivering bisphosphonates Compounds and compositions for the delivery of bisphosphonates are provided. Methods of preparation, administration and treatment are provided as well. ... | 12/18/2007 |
| 7279502 | Polyamine analog conjugates and quinone conjugates as therapies for cancers and prostate diseases Peptide conjugates in which cytocidal and cytostatic agents, such as polyamine analogs or naphthoquinones, are conjugated to a polypeptide recognized and cleaved by enzymes such as prostate-specific antigen (PSA) and cathepsin B are provided, as well as compositions... | 10/09/2007 |
| 7105575 | Methods for the treatment of neuro- disorders using aminothiol compounds The present invention relates to new uses of S-2-(3-aminopropylamino)ethyl dihydrogen phosphorothioate, (amifostine) and other aminothiol compounds to treat and reverse toxicities caused by therapeutic agents, radiation treatment or diabetes. In particular, the inve... | 09/12/2006 |
| 7053072 | Methods for the administration of amifostine and related compounds The present invention provides methods of administering amifostine, WR-1065, or a combination thereof, to patients receiving radiation therapy in a manner that significantly reduces or decreases the adverse or undesirable side-effects of the compounds as compared wi... | 05/30/2006 |
| 7045550 | Polyamines and analogs for protecting cells during cancer chemotherapy and radiotherapy Polyamine effectors are administered locally to provide protection against the adverse side-effects of chemotherapy or radiation therapy, such as alopecia, mucositis and dermatitis. Pharmaceutical preparations comprising one or more polyamine effectors formulated fo... | 05/16/2006 |
| 6998109 | Emu-based formulations with lidocaine for wound treatment by inhibiting microbial activity The present formulation is an analgesic, anesthetic and anti-pruritic formulation with from about 10.0 wt % to about 75.0 wt % Emu oil; from about 10.0 wt % to about 33.0 wt % benzyl alcohol; from about 0.25 wt % to about 5.0 wt % allantoin; from about 0.1 wt % to a... | 02/14/2006 |
| 6974593 | Insoluble drug delivery Particles of water insoluble biologically active compounds, particularly water-insoluble drugs, with an average size of 100 nm to about 300 nm, are prepared by dissolving the compound in a solution then spraying the solution into compressed gaz, liquid or supercriti... | 12/13/2005 |
| 6784168 | Biocidal compositions and treatments A synergistic biocide comprises a tris(hydroxymethyl)phosphine or a tetrakis (hydroxymethyl)phosphonium salt and at least one non-surfactant biopenetrant, such as a polymer or copolymer having a plurality of quaternary ammonium groups, a hydrotrope or a syntan, toge... | 08/31/2004 |
| 6680307 | Use of ibandronate for promoting osseointegration of endoprostheses The invention relates to use of ibandronic acid (1-hydroxy-3-(N-methyl-N-pentyl)aminopropyl-1,1-diphosphonic acid) or physiologically compatible salts or esters thereof for improving the osseointegration of cement-free anchored endoprostheses. Ibandronate... | 01/20/2004 |
| 6677320 | Parenteral bisphosphonate composition with improved local tolerance The present invention relates to a parenteral composition comprising a bisphosphonic acid or a pharmaceutically acceptable salt thereof (bisphosphonate) as active component and a pharmaceutically acceptable chelating agent, processes of the preparation of... | 01/13/2004 |
| 6627660 | Stabilized thyroxine compounds Throxinyldimethylphosphinate was invented as a prodrug to stabilize thyroxine, a drug widely used to treat hypothyroidism. The presence of the dimethylphosphinate group at the phenolic hydroxyl of thyroxine is key to preventing thyroxine from decomposing ... | 09/30/2003 |
| 6528040 | EMU oil-based formulations for use as an analgesic, anesthetic and antipruritic An analgesic, anesthetic and antipruritic formulation is provided containing 0.01 to 13 wt % alkyl esters; and 20 to 70 wt % Emu oil; 10 to 33 wt % benzyl alcohol; 10 to 33 wt % benzoin; 0.2 to 2 wt % allantoin; 0.25 to 1.25 wt % methylparaben and 0.01 to... | 03/04/2003 |
| 6468559 | Enteric coated formulation of bishosphonic acid compounds and associated therapeutic methods Oral dosage forms are provided for the administration of a bisphosphonic acid compound in the prevention and treatment of conditions involving calcium or phosphate metabolism, i.e., conditions associated with bone resorption such as osteoporosis, Paget's ... | 10/22/2002 |
| 6326363 | Methylenebisphosphonic acid derivatives The object of the invention are novel halogen substituted methylenebisphosphonic acid anhydrides, ester anhydrides, amide anhydrides, and ester amide anhydrides, processes for the preparation of these novel compounds, as well as pharmaceutical preparation... | 12/04/2001 |
| 6200961 | Concentrates of organophosphorous insecticides A low volatile organic compound co-solvent system is disclosed for preparing emulsion concentrates of low melting organophosphorous insecticides wherein the bioefficacy of the insecticide active is significantly enhanced. The co-solvent system comprises a... | 03/13/2001 |
| 6194004 | Dry mix formulation for bisphosphonic acids Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by direct compression/dry mix tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, ... | 02/27/2001 |
| 6114316 | Combination of bisphosphonate and tetracycline Tissue-destructive conditions related to excess protemase activity in a biological system are treated or prevented by administering to the system a composition which combines a tetracycline and a bisphosphonate in synergistic proteinase inhibiting amounts... | 09/05/2000 |
| 5824663 | Alternative enzyme substrates as deodorants The invention relates to a method of suppressing human body malodor by utilizing a deodorant composition containing a competitive substrate for the enzymatic creation of axillary body malodor.... | 10/20/1998 |
| 5616571 | Bisphosphonates prevent bone loss associated with immunosuppressive therapy Bisphosphonate, particularly alendronate, can prevent or treat bone loss associated with immunosuppressive therapy, whether or not the immunosuppressive therapy is associated with an organ transplant.... | 04/01/1997 |
| 5614510 | Pharmaceutical composition with improved bioavailability of inositol phosphate The invention relates to an inositol phosphate containing pharmaceutical composition which comprises a nitrogen-containing compound for improvement of the bioavailability of the inositol phosphate in mammals including man at non-parenteral administration.... | 03/25/1997 |
| 5514671 | Alternative enzyme substrates as deodorants The invention relates to a method of suppressing human body malodor by utilizing a deodorant composition containing a competitive substrate for the enzymatic creation of axillary body malodor.... | 05/07/1996 |
| 5438047 | Diphosphates of catecholamines and pharmaceutical compositions containing them Diphosphates of catecholamines having formula (I) wherein R, R1, R2, R3, R4, R5, R6, R7 and X have the meanings reported in the description, are useful in the therapy of cardiova... | 08/01/1995 |
| 5409911 | Prostaglandin analog for treating osteoporosis This invention relates to a prostaglandin-bisphosphonate compound of the formula: ##STR1## and its pharmaceutically acceptable salts. The claimed compounds are effective as delivery agents of prostaglandins to treat osteoporosis and related bone... | 04/25/1995 |
| 5360797 | Bisphosphonic acid derivatives useful as anti-arthritic agents Novel acids, esters, and salts of phenyl, naphthyl, quinoxalinyl, and biphenyl bisphosphonic acids and 1,2-oxaphosphepins are described. These compounds are useful as antiinflammatory and anti-arthritic agents. Also described are known compounds of the ph... | 11/01/1994 |
| 5358941 | Dry mix formulation for bisphosphonic acids with lactose Pharmaceutical compositions of bisphosphonic acids, and salts thereof, are prepared by direct compression/dry mix tablet formulation. These pharmaceutical compositions are useful in the treatment of disturbances involving calcium or phosphate metabolism, ... | 10/25/1994 |
| 5217964 | Polyamine thiols as radioprotective agents The present invention relates to certain polyamine thiols which are useful as radioprotective agents.... | 06/08/1993 |
| 4643764 | Multiple types of microcapsules and their production In a process of encapsulating water-immiscible material within discrete capsules of polyurea without addition of a second reactant, whereby hydrolysis of an isocyanate monomer to form an amine takes place which in turn reacts with another isocyanate monom... | 02/17/1987 |
| 4397846 | Storage-stable lipid vesicles and method of preparation Lipid vesicles, such as those containing inositol hexaphosphate useful for improving the oxygen-release of intact erythrocytes, may be rendered stable to long term storage at temperatures below the freezing point of the encapsulated solution, by rapid fre... | 08/09/1983 |
| 4228614 | Floating pesticide dispenser A method and composition for dispensing through a slow release floating polymer a pesticide for destroying aqueous pests, especially mosquito larva. The polymer matrix which has a specific gravity of less than 1.0 so that it floats, may be shaped into any... | 10/21/1980 |
| 4041151 | Resin compositions containing 0,0,0',0'-tetramethyl 0,0'-thiodi-p-phenylene phosphorothioate This invention relates to novel resin compositions containing 0,0,0',0'-tetramethyl 0,0'-thiodi-p-phenylene phosphorothioate. More particularly, this invention relates to novel dry blended polyvinyl chloride resin compositions containing 0,0,0',0'-tetrame... | 08/09/1977 |
| 3968207 | Method of controlling fleas and ticks on cats and dogs This invention relates to the use of O,O,O',O'-tetramethyl O,O'-thiodi-p-phenylene phosphorothioate insecticidal and acaricidal compositions in cats and dogs.... | 07/06/1976 |
| 3966919 | O,O,O',O'-Tetraalkyl, O,O'-vinylenedi-p-phenylene phosphorothioates and compositions containing the same for the control of siphonaptera infestations Method of using O,O,O',O'-tetraalkyl(C1 -C4)- O,O'-vinylenedi-p-phenylene phosphorothioates for the control of siphonaptera infestations and compositions containing said phosphorothioates as the active component, are described.... | 06/29/1976 |
