Celebrity Inventors
Comic actor Danny Kaye received patent D166,807 for the co-design of "Blowout Toy or the Like". It's similar to one of those toys that unravels when you blow into at a birthday party except Kaye's has three blowouts going in different directions, not just one.
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 8178514 | Inositol pyrophosphates, and methods of use thereof The present invention comprises compounds, compositions thereof, and methods capable of delivering modified inositol hexaphosphate (IHP) comprising an internal pyrophosphate ring to the cytoplasm of mammalian cells. In certain embodiments, the present invention rela... | 05/15/2012 |
| 7915238 | Immunomodulatory compounds and methods of use thereof The present invention is directed to methods of treating diseases and disorders related to immune responses by administering one or more immunomodulatory compounds. In particular, the invention is directed to methods of stimulating and reducing immune responses, the... | 03/29/2011 |
| 7833993 | Immunomodulatory compounds and methods of use thereof The present invention is directed to methods of treating diseases and disorders related to immune responses by administering one or more immunomodulatory compounds. In particular, the invention is directed to methods of stimulating and reducing immune responses, tre... | 11/16/2010 |
| 7833992 | Conjugates and compositions for cellular delivery This invention features conjugates, degradable linkers, compositions, methods of synthesis, and applications thereof, including cholesterol derived conjugates of biologically active compounds, including antibodies, antivirals, chemotherapeutics, peptides, proteins, ... | 11/16/2010 |
| 7361644 | Specific antagonist for both E- and P-selectins Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-med... | 04/22/2008 |
| 7109181 | Joint lubrication with P2Y purinergic receptor agonists The present invention is directed to a method of altering the amount or composition of synovial fluids secreted from joints in a subject in need of such treatment. The method comprises administering to a subject a pharmaceutical composition comprising a P2Y purinerg... | 09/19/2006 |
| 7094546 | Inhibitors of the inositol polyphosphate 5-phosphatase SHIP2 molecule The present invention is related to an inhibitor of the inositol polyphosphate 5-phosphatase SHIP2 protein or its encoding nucleotide sequence identified by SEQ ID NO. 1 or of SHIP2 mRNA expression. The present invention is also related to a pharmaceutical compositi... | 08/22/2006 |
| 7084126 | Methods and compositions for enhancing cellular function through protection of tissue components Methods and composisions for enhancing cellular function through protection of a tissue components such receptors, proteins, lipids, nucleic acids, carbohydrates, hormones, vitamins, and cofactors, by administering pyrophosphate analogs or related compounds. ... | 08/01/2006 |
| 7060685 | Compounds and methods for inhibiting selectin-mediated function Compounds and methods are provided for modulating in vitro and in vivo processes mediated by selectin binding. More specifically, selectin modulators and their use are described, wherein the selectin modulators that modulate (e.g., inhibit or enhance) a selectin-med... | 06/13/2006 |
| 7053150 | Segmented polymers and their conjugates Segmented water soluble polymers, containing a higher molecular weight segment linked to a lower molecular weight segment, are described. In one embodiment, the polymer segments are poly(ethylene glycol) segments. The segmented polymers are functionalized and are us... | 05/30/2006 |
| 6949517 | Method of treating inflammatory, tissue repair and infectious conditions The present invention relates to a method of treating inflammatory, tissue repair and infectious conditions in a mammal suffering therefrom which comprises administering to a mammal in need thereof an effective amount of a cyclic compound selected from the group con... | 09/27/2005 |
| 6943155 | Unique compositions of zwitterionic phospholipids and bisphosphonates and use of the compositions as bisphosphate delivery systems with reduced GI toxicity Compositions and methods for treating osteoporosis using the compositions are disclosed where the compositions have reduced GI toxicity and improved bio-availability and include a bisphosphonate and zwitterionic phospholipid. ... | 09/13/2005 |
| 6936452 | Inhibitors of the inositol polyphosphate 5-phosphate SHIP2 molecule The present invention is related to an inhibitor of the inositol polyphosphate 5-phosphatase SHIP2 protein or its encoding nucleotide sequence identified by SEQ ID NO. 1 or of SHIP2 mRNA expression. The present invention is also related to a pharmaceutical compositi... | 08/30/2005 |
| 6774180 | Synthesis of high molecular weight non-peptidic polymer derivatives High molecular weight derivatives of activated poly(ethylene glycol) and the like polymers are prepared in high purity by conjugating a large PEG molecule to a small PEG molecule. Most of the reaction steps can be accomplished on the more readily purified small mole... | 08/10/2004 |
| 6680307 | Use of ibandronate for promoting osseointegration of endoprostheses The invention relates to use of ibandronic acid (1-hydroxy-3-(N-methyl-N-pentyl)aminopropyl-1,1-diphosphonic acid) or physiologically compatible salts or esters thereof for improving the osseointegration of cement-free anchored endoprostheses. Ibandronate... | 01/20/2004 |
| 6677320 | Parenteral bisphosphonate composition with improved local tolerance The present invention relates to a parenteral composition comprising a bisphosphonic acid or a pharmaceutically acceptable salt thereof (bisphosphonate) as active component and a pharmaceutically acceptable chelating agent, processes of the preparation of... | 01/13/2004 |
| 6627660 | Stabilized thyroxine compounds Throxinyldimethylphosphinate was invented as a prodrug to stabilize thyroxine, a drug widely used to treat hypothyroidism. The presence of the dimethylphosphinate group at the phenolic hydroxyl of thyroxine is key to preventing thyroxine from decomposing ... | 09/30/2003 |
| 6605603 | Uses of 1-amino-3-(N,N-dimethylamino)-propylidene-1,1-bisphosphonic acid The present invention relates to novel uses of 1-amino-3-(N,N-dimethylamino)-propylidene-1,1-bisphosphonic acid or any of its soluble salts or any of its hydrates, in particular its use for the manufacture of a medicament for selective modulation of osteo... | 08/12/2003 |
| 6436913 | Use of estramustine phosphate in the treatment of bone metastasis Estramustine phosphate is shown to act as an inhibitor of bone resorption and can thus be used to treat, prevent or alleviate the symptoms of bone metastasis which arise due to said bone resorption.... | 08/20/2002 |
| 6337078 | Controlled delivery compositions and processes for treating organisms in a column of water or land Controlled release compositions of matter are disclosed comprising complexes for treating a population of one or more aquatic organisms in a column of water. The complexes comprise at least one system wherein the system comprises at least one bioactive ag... | 01/08/2002 |
| 6326363 | Methylenebisphosphonic acid derivatives The object of the invention are novel halogen substituted methylenebisphosphonic acid anhydrides, ester anhydrides, amide anhydrides, and ester amide anhydrides, processes for the preparation of these novel compounds, as well as pharmaceutical preparation... | 12/04/2001 |
| 6316430 | Insecticidal and miticidal compositions The invention relates to an insecticidal and miticidal composition which contains as active ingredients chlorfenapyr in combination with one or more organophosphoric acid ester-type compounds and to a method for controlling insecticidal or miticidal pests... | 11/13/2001 |
| 6303588 | Therapeutic methods utilizing naturally derived bio-active complexes and delivery systems therefor Methods are disclosed for correcting biological information transfer in a patient in need of such therapy which comprise administration to a patient of a composition comprising a therapeutically effective amount of a biocomplex comprising at least one bio... | 10/16/2001 |
| 6221856 | Inositol derivatives for inhibiting superoxide anion production Inositol derivatives, compositions comprising inositol derivatives, and methods for using compositions comprising inositol derivatives as agents for inhibiting superoxide anion production are described. The inositol derivatives are obtainable via conventi... | 04/24/2001 |
| 6200961 | Concentrates of organophosphorous insecticides A low volatile organic compound co-solvent system is disclosed for preparing emulsion concentrates of low melting organophosphorous insecticides wherein the bioefficacy of the insecticide active is significantly enhanced. The co-solvent system comprises a... | 03/13/2001 |
| 6114316 | Combination of bisphosphonate and tetracycline Tissue-destructive conditions related to excess protemase activity in a biological system are treated or prevented by administering to the system a composition which combines a tetracycline and a bisphosphonate in synergistic proteinase inhibiting amounts... | 09/05/2000 |
| 5998485 | Method for modulating immune response with inositol A composition for modulating immune response in mammals, comprises a therapeutic agent such as a stereoisomer of inositol, derivatives, salts, and mixtures thereof, and optionally a carrier. The composition is provided in solid and liquid formulations, in... | 12/07/1999 |
| 5955453 | Membrane-permeant phosphoinositides Membrane-permeant phosphoinositides, including phosphatidylinositol phosphate esters, are described. A membrane-permeant phosphoinositide includes groups that neutralize the charges of the phosphate moieties of the phosphoinositide. A cell can be treated ... | 09/21/1999 |
| 5885974 | Therapeutic methods utilizing naturally derived bio-active complexes and delivery systems therefor Methods are disclosed for correcting biological information transfer in a patient in need of such therapy which comprise administration to a patient of a composition comprising a therapeutically effective amount of a biocomplex comprising at least one bio... | 03/23/1999 |
| 5846957 | Use of an ester of inositoltrisphosphate for the preparing of medicaments The present invention relates to the use of an ester of inositoltrispbosphate for the preparing of a medicament effective against retroviral diseases.... | 12/08/1998 |
| 5827837 | Polyanion anti-inflammatory agents Selectin binding and inflammation is modulated by a method which utilizes inositol polyaninon.... | 10/27/1998 |
| 5827838 | Method for the treatment of diseases related with protein isoprenylation The invention provides a method for inhibiting protein isoprenylation by administration of a polyisoprenyl pyrophosphate analogue. The polyisoprenyl pyrophosphate analogue may have formula 1, ##STR1## wherein: Pren represents a C10 -C... | 10/27/1998 |
| 5760022 | Pharmaceutical composition with improved bioavailability of inositol phosphate The invention relates to an inositol phosphate containing pharmaceutical composition which comprises an aliphatic ester or ether for improvement of the bioavailability of the inositol phosphate in mammals including man at non-parenteral administration. Th... | 06/02/1998 |
| 5726163 | Dermatologic composition A dermatologic composition is disclosed which comprises a hydrogenated phospholipid having an iodine value of 10 or less and a phosphatidylcholine content of 90% or more, a cholesterol and an oily ingredient.... | 03/10/1998 |
| 5726164 | Nanosuspensions for intravenous administration The present invention relates to a pharmaceutical composition for the intravenous administration of the sparingly soluble staurosporin derivative N-benzoyl-staurosporin. The composition comprises the following preferred components: a) the therpeutic agent... | 03/10/1998 |
| 5668120 | Iontophoretic delivery of bisphosphonates to the alveolar bone The present invention relates to methods of inhibiting alveolar bone resorption or the undesirable movement of teeth of a human or other animal comprising: a) administering a reservoir to the gingival tissue of the oral cavity such that the reservoir is i... | 09/16/1997 |
| 5663179 | Certain isoquinoline derivatives having anti-tumor properties Compounds are described of general formula (I) ##STR1## and salts and solvates thereof, including physiologically acceptable salts and solvates thereof, in which: Z represents either Het, ##STR2## Het represents an optionally substituted bicycli... | 09/02/1997 |
| 5628986 | Oral compositions Disclosed are oral compositions such as toothpastes, mouthrinses, liquid dentifrices, lozenges and gums containing at least one phosphate derivative and a copper source.... | 05/13/1997 |
| 5618804 | Methanediphosphonic acid derivative, process for production thereof and use for pharmaceuticals A methane diphosphonic acid derivative represented by the general formula (I): ##STR1## wherein, X and Y are defined in the specification; m represents an integer of 0 to 3; n represents an integer of 0 to 4; and each X of the (X)m an... | 04/08/1997 |
| 5616571 | Bisphosphonates prevent bone loss associated with immunosuppressive therapy Bisphosphonate, particularly alendronate, can prevent or treat bone loss associated with immunosuppressive therapy, whether or not the immunosuppressive therapy is associated with an organ transplant.... | 04/01/1997 |
