Did You Know...
...that Robert Adler has the dubious distinction of being the Father of the Couch Potato? Back in 1955 Adler was employed by what was then Zenith Radio Corp., where he was charged to invent something that would allow viewers to turn down the TV volume without leaving their chairs. After a series of flops (such as a wired contraption that people tripped over), Adler hit on the idea of using sound waves. Thus the Remote Control was born...
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| Number | Title | Issue Date |
| 7897402 | Chromophore and polymer capable of detecting the presence of various neurotoxins and method of use Applicants have produced a chromophore and a polymer that are highly sensitive to the presence of various agents, including organophosphates, pesticides, neurotoxins, metal ions, some explosives, and biological toxins. The detection is accomplished by detecting a ch... | 03/01/2011 |
| 7879617 | Method, device and apparatus for measuring the concentration of creatinine, and method, device and apparatus for measuring the amount of salt in urine using the same A method for measuring the concentration of creatinine includes the steps of: (A) mixing a sample containing creatinine with a creatinine quantitative reagent including 1-methoxy-5-methylphenazinium in the absence of picric acid and any enzyme responsive to creatini... | 02/01/2011 |
| 7820449 | Test strip for creatinine determination The present invention provides a novel test piece for creatinine measurement. The test piece includes a compound expressed by the following formula (1), a metal that forms a colored complex with the compound, and a buffer agent in a porous material. The amount of cr... | 10/26/2010 |
| 7816145 | Method, device and apparatus for measuring the concentration of creatinine, and method, device and apparatus for measuring the amount of salt using the same A method for measuring a concentration of creatinine includes the steps of: (A) mixing a sample containing creatinine with a creatinine quantitative reagent containing a metal complex of at least one of hexacyanoferrate and hexacyanoruthenate in the absence of picri... | 10/19/2010 |
| 7393692 | SERS method for rapid pharmacokinetic analysis of drugs in saliva The method and apparatus rapidly separate drugs and their metabolites from saliva and, in a continuous sequence of steps, rapidly detect, identify and quantify them through surface-enhanced Raman spectroscopy. ... | 07/01/2008 |
| 7393691 | SERS method and apparatus for rapid extraction and analysis of drugs in saliva The method and apparatus rapidly separate drugs and their metabolites from saliva and, in a continuous sequence of steps, rapidly detect, identify and quantify them through surface-enhanced Raman spectroscopy. ... | 07/01/2008 |
| 7332345 | Chemical sensor system A chemical sensing apparatus and method for the detection of sub parts-per-trillion concentrations of molecules in a sample by optimizing electron utilization in the formation of negative ions is provided. A variety of media may be sampled including air, seawater, d... | 02/19/2008 |
| 7255835 | Single pass attenuated total reflection fourier transform infrared microscopy apparatus and method for identifying protein secondary structure, surface charge and binding affinity Apparatus and method for acquiring an infrared spectrum of a sample having or suspected to have an amide I band, an amide II band, an amide III band, an amide A band, an OH stretching region or a combination thereof. A representative method includes providing a samp... | 08/14/2007 |
| 7198955 | Method and apparatus for measurement of blood substitutes A method is disclosed whereby the concentration of a blood substitute, such as cross-linked hemoglobin, in a serum or plasma specimen is rapidly and accurately identified and quantified. The method further takes the measured concentration of the blood substitute and... | 04/03/2007 |
| 7195922 | Allergen detection A method of determining allergen activity in dust comprises: providing a dust sample; extracting from the dust sample at least one breakdown component or proteins or peptides; reacting the extracted at least one breakdown component with a colorimetric amine detectio... | 03/27/2007 |
| 7192776 | Synthetic urine and method of manufacturing same A synthetic urine solution and method of its manufacture are disclosed. The solution includes water having a pH between 3 and 10. The solution further includes creatinine and means for removing bacteria from the solution so as to control or eliminate sepsis of the u... | 03/20/2007 |
| 7192781 | Methods for stabilizing 5-azacytidine in plasma The invention provides methods for stabilizing 5-azacytidine against hydrolysis in plasma. By extracting the 5-azacytidine into acetonitrile and zinc sulfate, the 5-azacytidine can be stored for at least about 3 hours at about room temperature, and for at least abou... | 03/20/2007 |
| 7118916 | Method of reducing analysis time of endpoint-type reaction profiles Methods, devices and kits for facilitating medical diagnostic assays and reducing the time required for taking of such assays. The methods comprise initiating a reaction, obtaining at least three measurements, at three different time points, of a value or level of a... | 10/10/2006 |
| 7081347 | Method for predicting cardiovascular events A method for assessing aspirin resistance and relative risk of a cardiovascular event in a patient taking aspirin is provided. The concentration of 11-dehydro-thromboxane B2 in a urine sample is measured and compared to a set of standardized quartile concentrations.... | 07/25/2006 |
| 7002670 | Optical sensor and method for measuring concentration of a chemical constituent using its intrinsic optical absorbance An improved optical sensor and method for measuring concentration of a chemical constituent where measurement interference from other chemical compounds is present in the solution is provided. More specifically, the invention relates to a system for measuring the am... | 02/21/2006 |
| 6872573 | Fluorescent creatinine assay A method of detecting creatinine in body fluids using an indicator which produces a fluorescent response when oxidized in the presence of a copperII/creatinine complex. A preferred indicator is 4-(1-methylhydrazino)-7-nitro benzooxadiazole (MNBDH). ... | 03/29/2005 |
| 6855828 | Detection of hypoxia Nitroaromatic compounds and immunogenic conjugates comprising a novel nitroaromatic compound and a carrier protein are disclosed. The invention further presents monoclonal antibodies highly specific for the claimed nitroaromatic compounds, the compounds' protein con... | 02/15/2005 |
| 6852858 | Process for purifying N-[3-(3-cyanopyrazolo[1,5-a]pyrimidin-7-yl)phenyl]-N-ethylacetamide (zaleplon) and crystalline forms of zaleplon accessible with the process Zaleplon can be separated from a regioisomer impurity by crystallization from selected solvents or by adding an anti-solvent to a solution of zaleplon and the regioisomer. Zaleplon crystalline Forms II, III, IV, and V are useful for the treatment of insomnia. These ... | 02/08/2005 |
| 6815214 | Pharmaceutical uses and synthesis of diketopiperazines The synthesis of novel diketopiperazines, their use in inhibiting cellular events such as those involving NFK-α, NFK-β and in the treatment of inflammation events, a combinatorial library of diverse diketopiperazines and process for their synthesis as a library an... | 11/09/2004 |
| 6790668 | Monitoring patient compliance and bioavailability of drugs by deproteinizing body fluids The present invention is a method for drug level detection by using a simplified and effective deproteinizing step from body fluids, such as plasma, blood, urine, saliva, tear fluid, followed by drug extraction and measurement using an accurate technique, such as a ... | 09/14/2004 |
| 6773922 | Reagentless analysis of biological samples Apparatus and method for determining at least one parameter, e.g., concentration, of at least one analyte, e.g., urea, of a biological sample, e.g., urine. A biological sample particularly suitable for the apparatus and method of this invention is urine. In general,... | 08/10/2004 |
| 6693105 | Hydroxyl-containing compounds Disclosed are therapeutic compounds having the formula: including resolved enantiomers, diastereomers, hydrates, salts, solvates or mixtures thereof where j is an integer from one to three. The core moiety is a bicyclic ring structure having at least one heter... | 02/17/2004 |
| 6649598 | 4,7-dichlorofluorescein dyes as molecular probes Long wavelength, narrow emission bandwidth fluorecein dyes are provided for detecting specially overlapping target substances. The dyes comprise 4,7-dichlorofluoresceins, and particularly 2',4',5',7'-tetrachloro-4,7-dichloro-5-(and 6-) carboxyfluoresceins... | 11/18/2003 |
| 6558956 | Method and apparatus for detection of a controlled substance Techniques and devices for detecting and analyzing controlled substances and the like are discussed including highly reactive sensor molecules which are coated on a spectroscopic sample surface (4) and which may chemically react with a given analyte to fo... | 05/06/2003 |
| 6541273 | Multiple sorbent cartridges for solid phase extraction Methods and apparatus are disclosed which are useful for detecting the presence of various pesticides, including aryl pyrazoles such as fipronil. Pesticide residues are extracted from a variety of samples, including soil and/or water samples using techniq... | 04/01/2003 |
| 6524864 | Test strip for simultaneous detection of a plurality of analytes A test strip for simultaneously measuring a plurality of analytes in blood or other fluids comprising a plurality of reagent pads containing reagents specific to particular analytes located on a support. Each reagent pad is covered and in close contact wi... | 02/25/2003 |
| 6436721 | Device and method for obtaining clinically significant analyte ratios Disclosed is a method for determining the concentration of an analyte in a sample of body fluid. The method involves contacting the body fluid sample with a test strip containing mobile, labeled specific binding partner for the analyte, through which stri... | 08/20/2002 |
| 6416762 | Anti-picornaviral ligands via a combinatorial computational and synthetic approach The present invention provides structure-based combinatorial libraries of compounds containing the functional group minima of picornaviruses including poliovirus and rhinovirus. The libraries can be used to screen for therapeutical antiviral compounds, e.... | 07/09/2002 |
| 6379969 | Optical sensor for sensing multiple analytes A device for analyzing simultaneously multiple analytes in a fluid of unknown composition. The device includes a plurality of sensors, a light source for providing light to shine on the sensors, light detectors, and a processor. The sensors are exposed to... | 04/30/2002 |
| 6340764 | Reference compound for use in the analysis of levosimendan batches A pyridazinyl derivative (I) and its use as a reference compound in the determination of potentially genotoxic impurities in levosimendan samples. An analytic method for the determination of potentially genotoxic impurities in levosimendan samples wherein... | 01/22/2002 |
| 6333198 | Compound and its use A method of testing the purity or stability to degradation of a sample of lamotrigine or a pharmaceutical dosage form comprising lamotrigine comprises assaying the said sample for the presence of a compound selected from 3-amino-6-(2,3-dichlorophenyl)-1,2... | 12/25/2001 |
| 6326209 | Measurement and quantification of 17 ketosteroid-sulfates as a biomarker of biological age The present invention provides an improved method for using the measurement of total urinary 17 KS-S, referred to herein as the urinary Anabolic/Catabolic Index (ACI), as part of a biomarker for biological age.... | 12/04/2001 |
| 6210971 | Assay for the detection of creatinine Disclosed is an improved method for the detection of creatinine in a fluid test sample by contacting the test sample with cupric ions, a hydroperoxide, citrate and an oxidizable dye which gives a colored response in the presence of oxygen free radicals an... | 04/03/2001 |
| 6096723 | 4,7-dichlorofluorescein dyes as molecular probes Long wavelength, narrow emission bandwidth fluorecein dyes are provided for detecting spacially overlapping target substances. The dyes comprise 4,7-dichlorofluoresceins, and particularly 2',4',5', 7'-tetrachloro-4,7-dichloro-5- (and 6-) carboxyfluorescei... | 08/01/2000 |
| 6093551 | Process and device for in vitro diagnosis of allergic disorders The invention relates to a process for the in vitro diagnosis of allergic, in particular also pseudo-allergic, immunological and environment-related disorders using live biopsy tissue samples. Also disclosed is a mobile incubation device for keeping the t... | 07/25/2000 |
| 6074881 | Method for the prevention of hemoglobin interference in reagent systems for measuring peroxidase activity The present invention involves an improvement to an assay for the activity of a metal chelate, such as copper II/creatinine, which activity is related to the concentration of the analyte in a fluid test sample. In carrying out the assay, there is combined... | 06/13/2000 |
| 6001656 | Method for the detection of creatinine Disclosed is an improvement to the assay for creatinine in fluid test samples by contacting the test sample with a reagent formulation containing cupric ions, a hydroperoxide and an oxidizable dye. The improvement involves the inclusion of one or more sel... | 12/14/1999 |
| 5958786 | Fluorescent polymeric sensor for the detection of creatinine The present invention provides a creatinine sensor material having a first layer of a protonated pH sensitive fluorophore immobilized in a hydrophobic polymer, wherein the fluorophore can react quantitatively with ammonia and the transducing moiety of the... | 09/28/1999 |
| 5916815 | Assaying system for illicit substances using intentional false positives to initially preserve anonymity An assaying system for determining the presence of particular illicit substances in human physiological fluid, consisting of a collection cup, a collection cup lid, and a test card with assaying means, quality control means and adulteration detection mean... | 06/29/1999 |
| 5885778 | 4, 7-dichlorofluorescein dyes as molecular probes Long wavelength, narrow emission bandwidth fluorecein dyes are provided for detecting spacially overlapping target substances. The dyes comprise 4,7-dichlorofluoresceins, and particularly 2',4',5',7'-tetrachloro-4,7-dichloro-5- (and 6-) carboxyfluorescein... | 03/23/1999 |
