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| Number | Title | Issue Date |
| 8148160 | Electrode for molecular sensing and method for molecular sensing Molecular sensing of target molecules is performed by using an electrode for molecular sensing in which detecting molecules which can shift a surface potential of the electrode by an interaction with the target molecules are bound directly or via coupling molecules ... | 04/03/2012 |
| 8017403 | Mass spectrometry method for measuring vitamin B6 in body fluid Provided are methods of detecting the presence or amount of the active form of vitamin B6, pyridoxal 5′-phosphate, in a body fluid sample using tandem mass spectrometry coupled with liquid chromatography. ... | 09/13/2011 |
| 7977110 | Method for distinguishing between kidney dysfunctions A method for distinguishing between kidney dysfunctions in a mammal, including pre-renal azotemia, an acute renal injury that may progress to acute renal failure, and chronic kidney disease, using a urinary or circulating NGAL assay result that is compared to a pred... | 07/12/2011 |
| 7648841 | Reagent for determining the absolute configuration of chiral compound and determination method The present invention relates to a reagent for determining the absolute configuration of a chiral compound containing as an active ingredient a metalloporphyrin dimer, wherein the metalloporphyrin dimer has an alkaline-earth metal ion as a central metal and has a ca... | 01/19/2010 |
| 7358093 | Aztreonam L-lysine and methods for the preparation and analysis thereof The present invention relates to the L-lysine salt of aztreonam and methods for making the L-lysine salt of aztreonam. ... | 04/15/2008 |
| 7332345 | Chemical sensor system A chemical sensing apparatus and method for the detection of sub parts-per-trillion concentrations of molecules in a sample by optimizing electron utilization in the formation of negative ions is provided. A variety of media may be sampled including air, seawater, d... | 02/19/2008 |
| 7297940 | Method, apparatus, and program product for classifying ionized molecular fragments Apparatus, methods, and program products are disclosed that classify spectral peaks in dissociation spectrum data and thereby improves the efficiency of molecular sequencing. ... | 11/20/2007 |
| 7267994 | Element-coded affinity tags The present invention provides compositions and methods for detecting, analyzing, and identifying biomolecules. More particularly, the invention provides Element Coded Affinity Tags comprising a metal chelate and a metal ion and methods of using the tags to detect, ... | 09/11/2007 |
| 7267990 | Chelation of charged and uncharged molecules with porphyrin-based compounds Porphyrins containing one or more neutral or negatively-charged, closo- or nido-carborane substituents are useful as chelators. The carbon-carbon bonds linking the boron-containing groups to the porphyrin ring make the compounds highly resistant to hydrolysis. These... | 09/11/2007 |
| 7264777 | Measurement of surface areas by polyvinylpyrrolidone sorption A method of quantitatively determining surface area of a sample uses polyvinylpyrrolidone (PVP) dispersed in a solution containing the sample, and determining the amount of PVP that has deposited on the sample. ... | 09/04/2007 |
| 7262293 | Aztreonam L-lysine and methods for the preparation thereof The present invention relates to the L-lysine salt of aztreonam and methods for making the L-lysine salt of aztreonam. ... | 08/28/2007 |
| 7262060 | Method for assessing nicotine dependence A method for assessing nicotine dependence, which involves measuring a whole blood, serum or platelet-rich plasma serotonin level and rating the whole blood, serum or platelet-rich plasma serotonin level on such a scale that the higher it is, the higher nicotine dep... | 08/28/2007 |
| 7255835 | Single pass attenuated total reflection fourier transform infrared microscopy apparatus and method for identifying protein secondary structure, surface charge and binding affinity Apparatus and method for acquiring an infrared spectrum of a sample having or suspected to have an amide I band, an amide II band, an amide III band, an amide A band, an OH stretching region or a combination thereof. A representative method includes providing a samp... | 08/14/2007 |
| 7214545 | Element-coded affinity tags The present invention provides compositions and methods for detecting, analyzing, and identifying biomolecules. More particularly, the invention provides Element Coded Affinity Tags comprising a metal chelate and a metal ion and methods of using the tags to detect, ... | 05/08/2007 |
| 7198955 | Method and apparatus for measurement of blood substitutes A method is disclosed whereby the concentration of a blood substitute, such as cross-linked hemoglobin, in a serum or plasma specimen is rapidly and accurately identified and quantified. The method further takes the measured concentration of the blood substitute and... | 04/03/2007 |
| 7148069 | Method for analysis of compounds with amino group and analytical reagent therefor The present invention provides a method for the analysis of a compound with amino group (e.g., an amino acid or peptide) contained in a sample and convenient manner with a high sensitivity. The compound with amino group in a sample containing the compound with amino... | 12/12/2006 |
| 7144971 | Polycarbonates and photoconductive imaging members A polycarbonate generated from the polymerization of a protected hydroxylated bisphenolic compound, a bisphenol, a monophenolic endcapping agent, a bisphenol haloformate, and a curing compound, and thereafter subjecting the obtained polymer to a reaction with an aci... | 12/05/2006 |
| 7090993 | Method of assaying pyrrole-containing biological compounds This invention relates to a method of assaying pyrrole-containing biological compounds and chemical compositions that can be used in the method. The method involves contacting a biological compound with one of: a) a bound or bindable derivatizing agent ... | 08/15/2006 |
| 7067267 | Method of assaying pyrrole-containing biological compounds This invention relates to a method of assaying pyrrole-containing biological compounds and chemical compositions that can be used in the method. The method involves contacting a biological compound with one of: a) a bound or bindab... | 06/27/2006 |
| 7033839 | Quick acting toxic ammonia test for aqueous samples A method, test reagent and device usable as a test strip for detecting toxic ammonia levels in water samples such as aquarium water. The volume of the water to be tested contacted with a soda lime reagent to raise the pH to at least 10, and simultaneously contacted ... | 04/25/2006 |
| 7000452 | Phased micro fluid analyzer A micro fluid analyzer having a concentrator and separator. A strip continuous through a channel in the concentrator may provide a hot zone that may move with the flow of fluid through the channel of the concentrator to provide a concentration of heat in the flow. A... | 02/21/2006 |
| 6964844 | Hybrid phthalocyanine derivatives and their uses Water soluble hybrid phthalocyanine derivatives useful in competitive and noncompetitive assays immunoassays, nucleic acid and assays are disclosed and claimed having (1) at least one donor subunit with a desired excitation peak; and (2) at least one acceptor subuni... | 11/15/2005 |
| 6830933 | Reference standards for determining the purity or stability of amlodipine maleate and processes therefor Amlodipine aspartate and amlodipine maleamide are used as reference standards or markers in determining the purity of amlodipine maleate substances and products. ... | 12/14/2004 |
| 6790668 | Monitoring patient compliance and bioavailability of drugs by deproteinizing body fluids The present invention is a method for drug level detection by using a simplified and effective deproteinizing step from body fluids, such as plasma, blood, urine, saliva, tear fluid, followed by drug extraction and measurement using an accurate technique, such as a ... | 09/14/2004 |
| 6713306 | Method for identification of flunitrazepam A method for detecting the presence of flunitrazepam in a sample. Flunitrazepam contained within the sample is reduced and hydrolyzed by the addition of a hydrolyzing agent and a reducing agent. A visualizing agent is provided to combine with the reduced and hydroly... | 03/30/2004 |
| 6649598 | 4,7-dichlorofluorescein dyes as molecular probes Long wavelength, narrow emission bandwidth fluorecein dyes are provided for detecting specially overlapping target substances. The dyes comprise 4,7-dichlorofluoresceins, and particularly 2',4',5',7'-tetrachloro-4,7-dichloro-5-(and 6-) carboxyfluoresceins... | 11/18/2003 |
| 6620624 | Mass spectrometry interface, a mass spectrometer and a mass spectrometry With rotating and translating a rotation-translation drum installed in a vacuum chamber of a mass spectrometry interface to constitute a mass spectro-meter, a liquid sample incorporating a dissolved substance to be analyzed in its mass is emitted for the ... | 09/16/2003 |
| 6608178 | 5-hydroxytryptophol (5-HTOL) derivatives, antibodies, immunoassays and detection of recent alcohol consumption Antibody specific for a 5-HTOL compound. A glucuronide with 5-hydroxytryptophol (5-HTOL) characterized in that it comprises the structure of the ଲ-glucuronide between the 5-hydroxy group of 5-HTOL and D-glucopyranosiduronic acid. An immunoassay and ... | 08/19/2003 |
| 6558956 | Method and apparatus for detection of a controlled substance Techniques and devices for detecting and analyzing controlled substances and the like are discussed including highly reactive sensor molecules which are coated on a spectroscopic sample surface (4) and which may chemically react with a given analyte to fo... | 05/06/2003 |
| 6472222 | Method of estimating rate of nicotine metabolism in individuals A simple screening method is provided for determining biological variations among individuals in a smoking cessation program so that a therapy regimen can be adjusted appropriately for each individual. The method includes the steps of having an individual... | 10/29/2002 |
| 6417006 | Assay method for cardiovascular disease An assay method for detecting potential cardiovascular disease (CVD) in a vascularized subject by assessing the concentration of holo-transcobalamin II (holo-TCII) in a sample from the subject where abnormally low levels of holo-TCII are indicative of CVD... | 07/09/2002 |
| 6333198 | Compound and its use A method of testing the purity or stability to degradation of a sample of lamotrigine or a pharmaceutical dosage form comprising lamotrigine comprises assaying the said sample for the presence of a compound selected from 3-amino-6-(2,3-dichlorophenyl)-1,2... | 12/25/2001 |
| 6296810 | Apparatus for DNA sequencing The present invention provides a method and apparatus for automated DNA sequencing. The method of the invention includes the steps of: a) using a processive exonuclease to cleave from a single DNA strand the next available single nucleotide on the strand;... | 10/02/2001 |
| 6265220 | Assay for homocysteine A non-immunochemical method is disclosed for determining homocysteine in a sample. A combination of the sample and a first compound that comprises a cis-1,4-dioxo-2-butene moiety or hydrolytically derived precursor thereto is provided in a liquid medium. ... | 07/24/2001 |
| 6133040 | Process and test kit for cocaine detection Test kit and method for discriminating cocaine and its salts from substances that falsely give a positive color reaction with Scott's thiocyanate reagent. As all Scott false positive substances have lower pKa values than cocaine, or in their basic from hi... | 10/17/2000 |
| 6130044 | Surfaces for biological reactions, process for preparing them and process for their use A highly specific surface for biological reactions, which includes a support with at least one essentially compact layer of an organic compound. On the outside of the organic compound layer is an exposed group containing an ethylenic double bond, which ha... | 10/10/2000 |
| 6096723 | 4,7-dichlorofluorescein dyes as molecular probes Long wavelength, narrow emission bandwidth fluorecein dyes are provided for detecting spacially overlapping target substances. The dyes comprise 4,7-dichlorofluoresceins, and particularly 2',4',5', 7'-tetrachloro-4,7-dichloro-5- (and 6-) carboxyfluorescei... | 08/01/2000 |
| 6057161 | Method for determination of drugs of abuse in biological samples A high purity styrene-divinyl benzene resin is used for rapid solid phase extraction of drugs of abuse from body fluid samples. Simple extraction procedures are described which provide high recovery and selectivity for a wide variety of drugs. A convenien... | 05/02/2000 |
| 6054322 | Use of sialic acid determination for determining alcohol consumption A method for the determination of an individual's alcohol consumption, characterized in comprising the steps: i) determining the level of sialic acid in a body fluid sample from the individual; ii) comparing the level found in step (i) with the level for ... | 04/25/2000 |
| 6034267 | Esters of 5-aminolevulinic acid as photosensitizing agents in photochemotherapy The invention provides a pharmaceutical compositions comprising a compound of formula I: R22 N--CH2 COCH2 --CH2 CO--OR1(I) wherein, R1 and R2 have any of the values defined in t... | 03/07/2000 |
