Celebrity Inventors
Mark Twain (Samuel L. Clemens) received Patent No. 121,992 for "An Improvement in Adjustable and Detachable Straps for Garments." He later received two more patents: one for a self-pasting scrapbook and one for a game to help players remember important historical dates.
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| Number | Title | Issue Date |
| 8143068 | Oxidation resistant indicator molecules Compounds having enhanced oxidation stability are disclosed. The compounds have an aryl boronic acid residue having one or more electron withdrawing groups on the aromatic moiety which contains the boronic acid residue, such that the molecule has enhanced oxidation ... | 03/27/2012 |
| 8048680 | Holographic sensor A sensor for the detection of an analyte comprising a cis-diol moiety, which comprises a holographic element comprising a medium and a hologram disposed throughout the volume of the medium, wherein an optical characteristic of the element changes as a result of a va... | 11/01/2011 |
| 8008088 | SMMR (small molecule metabolite reporters) for use as in vivo glucose biosensors Small Molecule Metabolite Reporters (SMMRs) for use as in vivo glucose biosensors, sensor compositions, and methods of use, are described. The SMMRs include boronic acid-containing xanthene, coumarin, carbostyril and phenalene-based small molecules which are used fo... | 08/30/2011 |
| 8003397 | Glucose monitoring by viscometric sensing of polymeric fluid A polymeric sensing fluid for detecting the presence of glucose and systems and methods of its use are generally disclosed. The polymeric sensing fluid includes a polymer in a solvent (e.g., an aqueous solvent). The polymer has a plurality of boronic acid moieties e... | 08/23/2011 |
| 7972862 | Noninvasive glucose monitor A method of sensing glucose in subjects includes the steps of providing a sensing solution including a plurality of metal ions, introducing a bodily fluid sample from a subject into the sensing solution. An optically-based measurable derived from directing incident ... | 07/05/2011 |
| 7972861 | Methods for performing hematocrit adjustment in glucose assays and devices for same Methods and devices for performing in situ hematocrit adjustments during glucose testing using glucose-monitoring products and using those adjusted values to estimate the hematocrit value of blood samples to reduce or eliminate the assay bias caused by the different... | 07/05/2011 |
| 7951605 | Multianalyte sensor The invention relates to devices for continuously measuring the concentrations of more than one target analyte. Specifically, the devices comprise a plurality of analyte binding domains, with each domain being capable of specifically and reversibly binding to at lea... | 05/31/2011 |
| 7939332 | Detection of analytes in aqueous environments The invention relates to indicator molecules for detecting the presence or concentration of an analyte in a medium, such as a liquid, and to methods for achieving such detection. More particularly, the invention relates to copolymer macromolecules containing relativ... | 05/10/2011 |
| 7927882 | Instrument A method and apparatus for performing a first measurement on a biological fluid or control, which first measurement varies with both the concentration of a first component and at least one of the presence and concentration of a second component. The method and appar... | 04/19/2011 |
| 7923258 | Instrument A method and apparatus for performing a first measurement on a biological fluid or control, which first measurement varies with both the concentration of a first component and at least one of the presence and concentration of a second component. The method and appar... | 04/12/2011 |
| 7851225 | Oxidation resistant indicator molecules Compounds having enhanced oxidation stability are disclosed. The compounds have an aryl boronic acid residue having one or more electron withdrawing groups on the aromatic moiety which contains the boronic acid residue, such that the molecule has enhanced oxidation ... | 12/14/2010 |
| 7829341 | Polyviologen boronic acid quenchers for use in analyte sensors The invention relates to a class of glucose-responsive, polyviologen boronic acid quenchers that may be used in combination with fluophores to achieve real-time measurement of glucose levels in vivo. ... | 11/09/2010 |
| 7824918 | HPTS-Mono and BIS Cys-Ma polymerizable fluorescent dyes for use in analyte sensors Novel fluorescent dyes are disclosed for use in analyte detection. In particular, mono- and bis-substituted HPTS dyes and methods of making them are provided. ... | 11/02/2010 |
| 7704747 | Dual blood glucose meter Disclosed herein is a dual blood glucose meter. The dual blood glucose meter includes a meter body, a measurement strip, a variety of electronic parts and upper and lower strip receiving ports. The meter body is provided with a liquid crystal display panel on the fr... | 04/27/2010 |
| 7629172 | Entrapped binding protein as biosensors The invention is directed to entrapped mutated binding proteins, mutated binding proteins containing reporter groups, compositions of mutated binding proteins containing reporter groups in analyte permeable matrixes, and their use as analyte biosensors both in vitro... | 12/08/2009 |
| 7494818 | Method for determining concentration of multiple analytes in a single fluid sample A multilayer test strip that measures concentrations of multiple analytes from a single whole blood sample. The test strip includes a test matrix of several layers held together in constant contact by a test strip holder. The invention is characterized in that it ha... | 02/24/2009 |
| 7439033 | Method and test strip for determining a fluid analyte A reagent strip for measuring the concentration of glucose in whole blood has a polymer on at least one side thereof to increase the opacity thereof, thereby reducing the effect of hematocrit on the glucose determination. ... | 10/21/2008 |
| 7432096 | Glucose dehydrogenase and production thereof The invention relates to novel PQQ-dependent soluble glucose dehydrogenases (sPQQGDH) from Acinetobacter and to a process for their preparation by overexpression in suitable microbial expression systems. ... | 10/07/2008 |
| 7431885 | Measuring device for the amperometric measurement of test strips A measuring device for the amperometric measurement of test strips 12, each having a test field moistenable by a liquid to be investigated and having measuring electrodes associated with the test field. The device includes at least one test strip receiver ... | 10/07/2008 |
| 7417164 | Fluorescent dyes for use in glucose sensing A novel class of compounds that includes HPTS-Cys-MA, and methods of making them are disclosed herein. The class of compounds including HPTS-Cys-MA are useful as fluorescent dyes for analyte detection. ... | 08/26/2008 |
| 7407811 | System and method for analyte measurement using AC excitation A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the an... | 08/05/2008 |
| 7407626 | Composition and method of use of medical test kit A medical test kit includes a glucose testing composition, a protein testing composition, a bilirubin testing composition, a bilinogen testing composition, an amylase testing composition, a blood testing composition, a calcium testing composition, a nitrite testing ... | 08/05/2008 |
| 7395158 | Method of screening for disorders of glucose metabolism A method of screening for disorders of glucose metabolism such as impaired glucose tolerance and diabetes allows prevention, or early detection and treatment of diabetic complications such as cardiovascular disease, retinopathy, and other disorders of the major orga... | 07/01/2008 |
| 7390663 | Process, composition and kit for providing a stable whole blood calibrator/control The present invention is directed toward a stable calibrator and/or control, kit and process for using in a glucose monitoring instrumentation. Principally, the instant invention teaches a glycolyzed red blood cell component which has been treated with a glycolysis ... | 06/24/2008 |
| 7390667 | System and method for analyte measurement using AC phase angle measurements A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the an... | 06/24/2008 |
| 7384791 | Method of analyzing blood A method of analyzing blood includes delivering a blood sample to a test device, applying a spatially varying electric field to the blood sample to provide a depleted cell concentration in a portion of the blood sample, and sensing a property of the portion of the b... | 06/10/2008 |
| 7374721 | Chip with measuring reliability and a method thereof A chip with measuring reliability and a method thereof are provided. The present invention serially connects a resistor having a resistance equal to or a little more than a maximum resistance of the chip itself to the resistor Rs of the chip so as to comp... | 05/20/2008 |
| 7371247 | Method and apparatus for penetrating tissue A tissue penetrating system includes a plurality of penetrating members each having a tip. A penetrating member driver is coupled to the plurality of penetrating members. Each tip of a penetrating member is uncovered during launch of the penetrating member by the pe... | 05/13/2008 |
| 7368085 | Analyte detector An analyte detector including a device having a surface, wherein the device is capable of detecting a charge adjacent to the surface. The surface includes a plurality of molecules bonded thereto, wherein the molecules have a structure (I): | 05/06/2008 |
| 7351213 | Integrated spot monitoring device with fluid sensor A bodily fluid sampling device is operable to breach the skin surface and allow bodily fluid to emerge from the breach location. The bodily fluid sampling device further evaluates the amount of bodily fluid emerged from breach location and determines whether the amo... | 04/01/2008 |
| 7338639 | System and method for analyte measurement A method of measuring an analyte in a biological fluid comprises applying an excitation signal having a DC component and an AC component. The AC and DC responses are measured; a corrected DC response is determined using the AC response; and a concentration of the an... | 03/04/2008 |
| 7335702 | Photochromic plastic object A photochromic plastic object made of a transparent synthetic resin material composed of at least two mutually penetrating polymer networks of different polymer materials and containing at least one photochromic dye homogeneously distributed therein, and a method fo... | 02/26/2008 |
| 7331931 | Method and apparatus for penetrating tissue These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes an electrically powered drive force generator. A penetrating member is operatively coupled to the force generator. The force generato... | 02/19/2008 |
| 7316700 | Self optimizing lancing device with adaptation means to temporal variations in cutaneous properties A lancing device, an embodiment of which controls the advancement and retraction of a lancet by monitoring the position of the lancet in conjunction with a lancet controller which incorporates a feedback loop for modulating the lancet driver to follow a predetermine... | 01/08/2008 |
| 7315767 | Impedance spectroscopy based systems and methods One aspect of the invention provides a device that non-invasively determines the concentration of a substance in a target. The device includes a first electrode, a measuring circuit, and a data processor. In one embodiment of the device, the first electrode can be e... | 01/01/2008 |
| 7303922 | Reagentless analysis of biological samples by applying mathematical algorithms to smoothed spectra Apparatus and method for determining at least one parameter, e. g., concentration, of at least one analyte, e. g., urea, of a biological sample, e. g., urine. A biological sample particularly suitable for the apparatus and method of this invention is urine. In gener... | 12/04/2007 |
| 7291117 | Method and apparatus for penetrating tissue These and other objects of the present invention are achieved in a body fluid sampling system for use on a tissue site that includes a voice coil based penetrating member driver. A plurality of penetrating members are included. A transport mechanism is configured to... | 11/06/2007 |
| 7282367 | Method for verifying amount of sample solution, method for controlling measurement system and method for measuring concentration of solution in apparatus for measuring optical characteristic A verification method of a sample solution amount includes the steps of: detecting at least one of a transmitted light component, a scattered light component and a reflected light component of a light by a photosensor while irradiating a sample solution, which is be... | 10/16/2007 |
| 7264971 | Read-head for optical diagnostic device A readhead for a photometric diagnostic instrument includes a housing adapted for incorporation within the photometric diagnostic instrument, and an elongated sample table operatively engaged with the housing. The sample table is configured to support elongated reag... | 09/04/2007 |
| 7258693 | Device and method for variable speed lancet A method of penetrating tissue is provided. The method comprises using a lancet driver to advance a lancet into the tissue; advancing the lancet at a first desired velocity in a first layer of tissue; advancing the lancet at a second desired velocity in a second lay... | 08/21/2007 |
