Quotables
"It is my heart-warmed and world-embracing Christmas hope and aspiration that all of us, the high, the low, the rich, the poor, the admired, the despised, the loved, the hated, the civilized, the savage (every man and brother of us all throughout the whole earth), may eventually be gathered together in a heaven of everlasting rest and peace and bliss, except the inventor of the telephone. "
Mark Twain ; Christmas greetings, 1890
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| Number | Title | Issue Date |
| 7410808 | Method and assay for detection of residues Embodiments described herein include methods and assays for detecting an analyte in a sample using a plurality of control zone capture agents. Some embodiments include detection of multiple analytes in a sample utilizing a plurality of analyte binders and a control ... | 08/12/2008 |
| 7393697 | Diagnostic test for analytes in a sample Diagnostic devices and methods are provided. The diagnostic devices preferably comprise a test strip with a test area. The sample to be analyzed contacts the test area, which comprises a specific binding partner for the analyte of interest. Analyte, if present in th... | 07/01/2008 |
| 7223848 | Methods for purifying Fc-containing proteins The present invention provides a process for dissociating Fc-containing molecules from complexes of Protein A/Fc-containing molecules or mixtures containing Fc-containing molecules and Protein A. The association, e.g., by hydrophobic interactions, between the Fc-con... | 05/29/2007 |
| 7071006 | Carrier holding micro-substances, system suspending such carriers apparatus for manipulating such carriers and method of controlling positions of such carriers Carriers hold remote-acting bodies which can be manipulated by a remote force, and also hold a micro-substance which is a target substance of an assay. The remote-acting bodies are manipulated in order to control the positions of the micro-substances, so as to execu... | 07/04/2006 |
| 7056657 | Apparatus and methods for magnetic separation Separation apparatus and method for separating magnetic and/or magnetically-labeled particles from a test medium. Test medium within a reaction chamber is caused to flow past a collecting surface, and a high-gradient magnetic field is applied to the surface t... | 06/06/2006 |
| 6972327 | Regeneration of chromatography material The invention provides improved methods of regenerating and using affinity chromatography material, in particular Protein A affinity chromatography resins. ... | 12/06/2005 |
| 6893881 | Method for detection of specific target cells in specialized or mixed cell population and solutions containing mixed cell populations The invention relates to a method for detecting specific target-cells in a simple and time saving way, using paramagnetic particles, antibodies recognizing the Fc portions of target-cell associating antibodies and target-cell associating antibodies directed to speci... | 05/17/2005 |
| 6870034 | Protein purification A method for purifying proteins by Protein A chromatography is described which comprises removing contaminants by washing the solid phase with various intermediate wash buffers. ... | 03/22/2005 |
| 6797814 | Protein purification A method for purifying proteins by Protein A chromatography is described which comprises the steps of: (a) adsorbing the protein to Protein A immobilized on a solid phase comprising silica or glass; (b) removing contaminants bound to the solid phase by washing the s... | 09/28/2004 |
| 6686169 | Reagent for the detection of Staphylococcus aureus by agglutination Reagents and methods for the detection of Staphylococcus aureus are provided. The reagents contain an antibody that binds to a capsular polysaccharide of type 5 of Staphylococcus aureus, and can be used in methods for detection of oxacillin resistant Stap... | 02/03/2004 |
| 6673614 | Rapid methods and kits for detection and semi-quantitation of anti-adenovirus antibody Methods for rapid detection and/or semi-quantitation of anti-adenovirus antibody are disclosed. Anti-adenovirus antibody is detected using a device comprising a membrane with adsorbed antigen which specifically binds anti-adenovirus antibody and an absorb... | 01/06/2004 |
| 6670192 | Apparatus for combined assay for current glucose level and intermediate or long-term glycemic control The present invention is directed to a single test system and method for determining the integrated glycemic condition of a subject by measuring the concentration of glucose and the level of protein-bound glucose in a subject's body fluid, such as whole b... | 12/30/2003 |
| 6613574 | Method to identify interface residue in biomolecular complex A method of identifying interface residues in a biomolecular complex are identified by selecting one molecule with residues to be identified, and the nonexchangeable hydrogens (protons) and not less than 70% of exchangeable hydrogens (protons) in the one ... | 09/02/2003 |
| 6509454 | Free solution ligand interaction molecular separation method The present invention is directed to novel methods for enhancing the ability to separate a species of interest from other different species present in a free solution mixture thereof which takes advantage of interactions that occur between soluble, small ... | 01/21/2003 |
| 6309646 | Protein-polysaccharide conjugate vaccines and other immunological reagents prepared using homobifunctional and heterobifunctional vinylsulfones, and processes for preparing the conjugates A method is disclosed for producing a soluble conjugate vaccine, and preferably protein/polysaccharide conjugates. In this process, the polysaccharide is reacted with a reagent so as to provide a functional group on the polysaccharide molecule. Once the f... | 10/30/2001 |
| 6303325 | Method for detecting analytes The invention relates to methods of determining the presence or amount of an analyte in a sample suspected of containing the analyte, said method comprising the steps of: (a) bringing together in an aqueous medium to form a mixture: (i) the sample; (ii) a... | 10/16/2001 |
| 6303390 | Method for antigen and antibody determination in bloodgroup serology Method and test kit for assaying in a sample an analyte which is a bloodgroup antigen present on erythrocytes or an antibody binding to such a bloodgroup antigen. To that end, the sample is treated with a reagent containing a binding partner for the analy... | 10/16/2001 |
| 6255048 | Highly sensitive fluoroassay This invention provides fluoroassay which comprises labeling analyte molecules with a fluorescent material having a nucleic acid portion stained with a sufficient number of fluorochrome molecules so as to be measurable as fluorescent spots, and a reactive... | 07/03/2001 |
| 6194552 | Immunosorbents with developed binding efficiency and method of manufacture The antitope of an antibody is masked with a masking agent, followed by immobilization on a support. The masking agent is then eluted to produce an improved immunosorbent, which is capable of binding more than double the amount of an antigen than existing... | 02/27/2001 |
| 6184043 | Method for detection of specific target cells in specialized or mixed cell population and solutions containing mixed cell populations The invention relates to a method for detecting specific target-cells in a simple and time saving way, using paramagnetic particles, antibodies recognizing the Fc portions of target-cell associating antibodies and target-cell associating antibodies direct... | 02/06/2001 |
| 6156524 | Reagent for the detection of Staphylococcus aureus by agglutination Reagents and methods for the detection of Staphylococcus aureus are provided. The reagents contain an antibody that binds to a capsular polysaccharide of type 5 of Staphylococcus aureus, and can be used in methods for detection of oxacillin resistant Stap... | 12/05/2000 |
| 6077940 | Free solution ligand interaction molecular separation method The present invention is directed to novel methods for enhancing the ability to separate a species of interest from other different species present in a free solution mixture thereof which takes advantage of interactions that occur between soluble, small ... | 06/20/2000 |
| 6013763 | Peptide variants of protein A Z domain variants of staphylococcal protein A have significantly reduced size but possess IgG-binding affinity equivalent to the wild type Z domain. These Z domain variants are suitable for use in affinity chromatography purification of proteins and in th... | 01/11/2000 |
| 5986066 | Biosensory layers A biologically recognizing layer on a solid phase consisting of biologically recognizing molecules comprising regions which recognize a substance to be analyzed and regions which do not recognize a substance to be analyzed. The biologically recognizing mo... | 11/16/1999 |
| 5958790 | Solid phase transverse diffusion assay The present invention relates to a method and kit for carrying out a qualitative or semi-quantitative assay. The invention uses a multi-layer device including an an uppermost cover layer of a water-impermeable material having a hole therein with a diamete... | 09/28/1999 |
| 5905028 | Method and apparatus useful for detecting bloodgroup antigens and antibodies The present invention is a method useful for the detection of bloodgroup antigens and antibodies. The method of the present invention is envisioned for two types of assays: a direct assay and an indirect assay. The direct assay comprises adding a sample o... | 05/18/1999 |
| 5798205 | Retrovirus from the HIV type O and its use (MVP-2901/94) A novel HIV type O immunodeficiency virus is disclosed which has the designation MVP-2901/94 and which has been deposited with the European Collection of Animal Cell Cultures (ECACC) under No. V 95012601. The characteristic antigens which can be obtained ... | 08/25/1998 |
| 5783087 | Method and apparatus for isolation and purification of immune complexes A system and method for isolating and purifying complexes of biologically active compounds. The inventive system and method utilize a centrifugal filtration device employing a membrane having ligands that preferentially bind a biologically active compound... | 07/21/1998 |
| 5773222 | Solid phase immunological assay A solid phase method of detection or assay of the presence or amount in a serum or plasma sample of a target antibody specific to a cell surface antigen. The sample is contacted with an immobilised preparation of cells bearing the antigen and antibody bou... | 06/30/1998 |
| 5728540 | Cytotoxic factor as is associated with multiple sclerosis, its detection and its quantification Gliotoxic factor in the isolated or purified state, characterized in that it possesses toxic activity with respect to human or animal astrocytic cells, having the effect of a cytomorphological disorganization of their network of intermediate filaments and... | 03/17/1998 |
| 5670623 | Methods of use of cellulose binding domain proteins A cellulose binding domain (CBD) having a high affinity for crystalline cellulose and chitin is disclosed, along with methods for the molecular cloning and recombinant production thereof. Fusion products comprising the CBD and a second protein are likewis... | 09/23/1997 |
| 5665558 | Method and apparatus useful for detecting bloodgroup antigens and antibodies The present invention is a method and apparatus useful for the detection of bloodgroup antigens and antibodies. There are two preferred embodiments of the method: a direct assay and an indirect assay. The direct assay comprises adding a sample of erythroc... | 09/09/1997 |
| 5597735 | Glycolipids for serodiagnosis of tuberculosis and leprosy A Dot-Blot assay ("spot test") with Bis-N,N,dioctadecylamide (BDA.TDA) as antigen was developed to detect anti-BDA.TDA antibodies in tuberculosis patients. To develop the antigen-antibody reaction, as a first step and in order to enhance the reaction, an ... | 01/28/1997 |
| 5580741 | Chemiluminescence immunoassay for chlorinated aromatic compound detection A sensitive chemiluminescence immunoassay method for field detection of the presence or the amount of low chlorinated biphenyl compounds in a solution is disclosed. The assay has a five minute analysis time and a working range of detection as low as about... | 12/03/1996 |
| 5561045 | Detection reagent, article, and immunoassay method The binding site on an immunoglobulin for a protein is blocked by hydrophobically coupling the immunoglobulin to a blocking agent such as a label. This results in a detection reagent useful in a variety of test assays in which a protein and an immunoglobu... | 10/01/1996 |
| 5543332 | Water-soluble, polymer-based reagents and conjugates comprising moieties derived from divinyl sulfone Water soluble reagents are claimed, comprising a water-soluble polymeric carrier molecule having attached thereto more than one connecting moiety wherein the connecting moiety is derived from divinyl sulfone, and wherein each connecting moiety is attached... | 08/06/1996 |
| 5492834 | Method of sample preparation for urine protein analysis with capillary electrophoresis Processes are provided for pretreating body fluid compositions and subsequently analyzing the pretreated body fluid compositions for analytes of interest. Processes for pretreating the compositions include providing size exclusion gel having a molecular w... | 02/20/1996 |
| 5466574 | Apparatus and methods for magnetic separation featuring external magnetic means A magnetic separator for isolating magnetically-labeled substances of interest, such as immunological agents, from a non-magnetic test medium using a method of high gradient magnetic separation. The target substance is contacted with microscopic magnetic ... | 11/14/1995 |
| 5424193 | Assays employing dyed microorganism labels The present invention relates generally to test articles and assays for the detection of analytes in biological fluid samples. More particularly, the present invention relates to test articles an assays which employ dyed microorganisms as visual labels to... | 06/13/1995 |
| 5384241 | Specific binding assay compound with inhibitive self-quenching characteristics Disclosed is an assay system including a compound comprising an analyte-specific moiety having substituted thereon a polymer comprising plurality of self-quenching emitter moieties and a plurality of isocharged functionality separating the emitter moietie... | 01/24/1995 |
