Quotables
"That’s an amazing invention, but who would ever want to use one of them?"
President Rutherford B. Hayes ; Said in 1876, after Alexander Graham Bell demonstrated the telephone to him at the White House
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7326535 | Immunoreactive peptides from Epstein-Barr virus Epstein-Barr virus (EBV) specific polypeptides are disclosed. Also disclosed are the use of these polypeptides for the production of polypeptide-specific antibodies and the diagnosis and treatment of EBV-associated disease. ... | 02/05/2008 |
| 7285218 | Method for the extra-corporeal qualitative and/or quantitative recording of neurotoxic substances in the blood plasma of an individual The invention relates to a method for the extra-corporeal qualitative and/or quantitative recording of neuro-toxic substances in the blood plasma of an individual. According to said method, a system containing neurones or neuronal networks, which have been cultivate... | 10/23/2007 |
| 7169550 | Diffraction-based diagnostic devices A biosensor includes a substrate with a receptive material layer of radiation-absorbing member (RAM)-tagged biomolecules disposed thereon. The receptive material is specific for an analyte of interest. A pattern of active and deactivated areas of the receptive mater... | 01/30/2007 |
| 6986995 | Methods of diagnosing liver fibrosis The present invention provides a method of diagnosing the presence or severity of liver fibrosis in an individual by detecting α2-macroglobulin (α2-MG) in a sample from the individual; detecting hyaluronic acid (HA) in a sample from the individual; detecting tissu... | 01/17/2006 |
| 6881821 | Hepatitis-C virus type 4, 5, and 6 Newly elucidated sequences of hepatitis C virus type 4 and type 5 are described, together with those of a newly discovered type 6. Unique type-specific sequences in the NS4, NS5 and core regions enable HCV detection and genotyping into types 1 to 6. Antigenic peptid... | 04/19/2005 |
| 6861212 | NANBV diagnostics and vaccines A family of cDNA sequences derived from hepatitis C virus (HCV) are provided. These sequences encode antigens which react immunologically with antibodies present in individuals with non-A non-B hepatitis (NANBH), but which are absent from individuals infected with h... | 03/01/2005 |
| 6849720 | Monoclonal antibodies to the human LDL receptor, their production and use There are provided monoclonal antibodies to the LDL receptor which are useful for the identification and purification of LDL and in treatment of e.g. hepatitis C infection. ... | 02/01/2005 |
| 6696242 | Recombinant proteins of a Pakistani strain of hepatitis E and their use in diagnostic methods and vaccines A strain of hepatitis E virus from Pakistan (SAR-55) implicated in an epidemic of enterically transmitted non-A, non-B hepatitis, now called hepatitis E, is disclosed. The invention relates to the expression of the whole structural region of SAR-55, desig... | 02/24/2004 |
| 6692907 | Conserved motif of hepatitis C virus E2/NS1 region The hypervariable region (E2HV) of the putative hepatitis C virus (HCV) glycoprotein E2/NS1, between about amino acid 384 to about amino acid 414, is a rapidly evolving region of HCV, and is likely to be under positive immune selection. A newly discovered... | 02/17/2004 |
| 6632682 | One-step immunoassay for the determination of antigen-specific antibodies of one of the immunoglobulin classes A, M, D, or E, and an agent suitable for this purpose An immunochemical method for the determination of antibodies which are specific for an antigen and are of one of the immunoglobulin classes: A, M, D or E in a fluid, with this fluid being contacted with a solid phase to which the antibodies against this i... | 10/14/2003 |
| 6610471 | Methods and compositions to investigate infection by hepatitis B virus and agents to prevent and treat the infection Methods and compositions that use the hepatitis B virus genome, and fragments or extensions, in a baculovirus vector, to develop anti-HBV agents and to drive high-level expression of a desired gene in a cell of hepatic origin.... | 08/26/2003 |
| 6596476 | Hepatitis C assay The present invention provides an improved assay for detecting the presence of an antibody to an HCV antigen in a sample by contacting the sample with at least one polypeptide containing at least one epitope of an HCV antigen. Preferred assay formats incl... | 07/22/2003 |
| 6576417 | Synthetic antigens for the detection of antibodies to hepatitis C virus Peptide sequences are provided which are capable of mimicking proteins encoded by HCV for use as reagents for screening of blood and blood products for prior exposure to HCV. The peptides are at least 5 amino acids long and can be used in various specific... | 06/10/2003 |
| 6541198 | Antibodies and other binding molecules specific for hepatitis B viral antigens The present invention relates to antibodies and other binding molecules specific for hepatitis B viral antigens (HBV), peptides comprising epitopes recognized by such molecules, and cell lines capable of producing antibodies. The invention is further conc... | 04/01/2003 |
| 6489131 | Interference reduction by rheumatoid factors The invention concerns a method for the determination of an analyte in which rheumatoid factors or rheumatoid-factor-like substances are added as an interference reducing reagent to reduce of avoid a hook effect. The invention in addition concerns suitabl... | 12/03/2002 |
| 6482602 | Reagent for the detection of Staphylococcus aureus by agglutination Reagents and methods for the detection of Staphylococcus aureus are provided. The reagents contain an antibody that binds to a capsular polysaccharide of type 5 of Staphylococcus aureus, and can be used in methods for detection of oxacillin resistant Stap... | 11/19/2002 |
| 6451578 | Non-A, non-B, non-C, non-D, non-E hepatitis reagents and methods for their use Hepatitis GB Virus (HGBV) nucleic acid and amino acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV nucleic acid or amino acid sequences, HGBV immunogenic particles, and antibodies which specifically bi... | 09/17/2002 |
| 6416944 | Methods of typing hepatitis C virus and reagents for use therein The claimed invention provides methods of detecting and typing HCV using nucleic acid molecules encoding type specific and type-cluster specific epitopes. The nucleic acid molecules flanking regions encoding type specific or type cluster specific epitopes... | 07/09/2002 |
| 6403298 | Method and apparatus for urine self-test intended for use in a toilet A method and apparatus for urine self testing wherein the apparatus is placed directly into the toilet after urination which avoids the direct placement and retention of an apparatus in the stream of urine as is common with urine testing devices. The appa... | 06/11/2002 |
| 6391540 | Method for detecting antibodies in a sample The present invention is directed to assays for detecting antibodies in a sample in a single incubation step. The assays employ universal solid phases and/or universal detectable markers, and facilitate the detection and differentiation of antigens from t... | 05/21/2002 |
| 6379886 | Diagnostic regeant for hepatitis C virus infection A diagnostic reagent for hepatitis C virus infection obtained by sensitizing a solid phase with HCV antigen and a conjugated antigen prepared by chemical bonding of HCV antigen and a carrier protein, and a method of diagnosing hepatitis C virus infection,... | 04/30/2002 |
| 6322965 | Chimera antigen peptide A chimera antigen peptide containing the epitope regions in the core region, the NS3 region, and the NS4 region of the HCV polypeptide. A sensitive detection of a wide range of infection by hepatitis C virus (HCV) can be carried out.... | 11/27/2001 |
| 6312889 | Combinations of hepatitis c virus (HCV) antigens for use in immunoassays for anti-HCV antibodies Combinations of HCV antigens that have a broader range of immunological reactivity than any single HCV antigen. The combinations consist of an antigen from the C domain of the HCV polyprotein, and at least one additional HCV antigen from either the NS3 do... | 11/06/2001 |
| 6306579 | Recombinant antigen from the NS3 region of the hepatitis C virus The present invention concerns a polypeptide which is composed of the amino acids 1207&#b1;10 to 1488&#b1;10 of a hepatitis C virus and of less than 20 foreign amino acids and the use of this polypeptide as an antigen in an immunological test.... | 10/23/2001 |
| 6303292 | Immunoreactive polypeptide compositions This invention relates generally to immunoreactive polypeptide compositions comprising hepatitis type C viral epitopes, methods of using the compositions in immunological applications, and materials and methods for making the compositions... | 10/16/2001 |
| 6300139 | FTCD antigen The present invention relates to FTCD antigen which is liver specific to serve as a diagnostic tool for Autoimmune Hepatitis type II. There is provided a human liver specific FTCD antigen recognized by LC1 antibodies which essentially consists in the amin... | 10/09/2001 |
| 6287761 | Synthetic antigens for the detection of antibodies to hepatitis C virus Peptide sequences are provided which are capable of mimicking proteins encoded by HCV for use as reagents for screening of blood and blood products for prior exposure to HCV. The peptides are at least 5 amino acids long and can be used in various specific... | 09/11/2001 |
| 6251584 | Specific binding assays using methyl orange The present invention relates to a method for improving the specificity of a specific binding assay by adding methyl orange to a coating solution in an amount sufficient for improving specificity of an immunoassay conducted using said coating. The present... | 06/26/2001 |
| 6235284 | Synthetic polypeptides belonging to the hepatitis C virus (HCV) and which can be used especially for detecting the latter The invention relates to a polypeptide comprising a peptide sequence belonging to the sequence of the first 62 amino acids of the terminal part of the CORE (or capsid) protein of the human hepatitis C virus (HCV), the polypeptide comprising either an isol... | 05/22/2001 |
| 6156499 | Methods for detecting antibodies to HAV 3C proteinase The present invention discloses methods for detecting antibodies to HAV 3C proteinase. These methods can distinguish an individual with a natural infection from one who has been vaccinated with an inactivated vaccine and are thus of utility in the diagnos... | 12/05/2000 |
| 6143510 | Measuring method using whole blood sample A method for quantitatively measuring analyte in an undiluted whole blood sample is disclosed which involves contacting an undiluted whole blood sample comprising the analyte with magnetically-responsive particles which comprise a first partner which is c... | 11/07/2000 |
| 6027874 | Immunoenzymatic conjugate, method for its productions, applications thereof Immunoenzymatic conjugate consisting of glycosylated labelling enzymes in copolymer form and substances having immunological activity. Method for the production of the conjugates according to the invention and use of the said conjugates in diagnostic kits.... | 02/22/2000 |
| 6022685 | Methods and compositions for detecting anti-hepatitis E virus activity The present invention provides antigenic peptides and polypeptides of hepatitis E virus. Also provided are mixtures of conjugated and unconjugated peptides of the present invention. Methods of detecting hepatitis E viral infection in a subject using the p... | 02/08/2000 |
| 6007982 | Synthetic antigens for the detection of antibodies to hepatitis C virus Peptide sequences are provided which are capable of mimicking proteins encoded by HCV for use as reagents for screening of blood and blood products for prior exposure to HCV. The peptides are at least 5 amino acids long and can be used in various specific... | 12/28/1999 |
| 6004561 | High level expression of polypeptide that contains modified preS1 region of hepatitis B virus large antigen The present invention relates to methods of producing recombinant molecules including the nucleotide sequence for the structure of the preS1 region of the surface glycoprotein of the hepatitis B virus, and to compositions of the molecules. Compositions of... | 12/21/1999 |
| 5989865 | Hepatitis B vaccine A variant HBsAg protein of fragment thereof displaying the antigenicity of Hepatitis B virus surface antigen is dicslosed, in which the variant protein of fragment thereof (vHBsAg) comprises a modified `a` determinant in which there is an amino acid other... | 11/23/1999 |
| 5935778 | Method for serological typing using type-specific antigens The invention concerns a method for typing antibodies in a sample liquid by means of type-specific antigens and in particular a method for typing antibodies to the hepatitis C virus and peptide antigens suitable for this.... | 08/10/1999 |
| 5925512 | Hepatitis B virus mutants, reagents and methods for detection Mutant Hepatitis B Virus (HBV) nucleic acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HBV nucleic acid sequences, HBV immunogenic particles, and a method for producing antibodies to HBV. Also provided ar... | 07/20/1999 |
| 5922532 | Synthetic antigens for the detection of antibodies to hepatitis C virus Peptide sequences are provided which are capable of mimicking proteins encoded by HCV for use as reagents for screening of blood and blood products for prior exposure to HCV. The peptides are at least 5 amino acids long and can be used in various specific... | 07/13/1999 |
| 5910404 | Synthetic antigens for the detection of antibodies to hepatitis C virus Peptide sequences are provided which are capable of mimicking proteins encoded by HCV for use as reagents for screening of blood and blood products for prior exposure to HCV. The peptides are at least 5 amino acids long and can be used in various specific... | 06/08/1999 |
