Bizarre Patents
Decorative Jeweled Wheel Cover
An improved wheel is provided wherein decorative items such as gem stones are embedded in either the wheel surface, a special mounting section attached to the wheel surface, or to a spoke strap that wraps around each spoke and positions embedded gem stones on the outside surface of the spoke.
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| Number | Title | Issue Date |
| 7387897 | Tetrameric antibody complexes for blocking non-specific labeling of antigens A method for preventing or inhibiting non-specific binding reactions between a detection reagent and an antigen in an immunological assay is described. The method involves using tetrameric antibody complexes that can bind to the antigen and are comprised of two mono... | 06/17/2008 |
| 7387772 | Chimeric, human and humanized anti-CSAP monoclonal antibodies The present invention provides humanized, chimeric and human anti-CSAp antibodies and anti-CSAp antibody fusion proteins that are useful for the treatment and diagnosis of various cancers, including colon cancer. ... | 06/17/2008 |
| 7368247 | Diagnostic assay for transmissible spongiform encephalopathies Heart and brain fatty acid binding proteins (H-FABP, B-FABP) are markers for TSEs, especially CJD. The invention provides a diagnostic assay for either of these markers, preferably by enzyme immunoassay using a specific antibody thereto. Since H-FABP is also a marke... | 05/06/2008 |
| 7166469 | Detection and determination of the stages of coronary artery disease A method having clinically sufficient degree of diagnostic accuracy for detecting the presence of coronary artery disease in a human patient from the general population and for distinguishing between the stages of the disease in that patient is disclosed. The stages... | 01/23/2007 |
| 7135340 | Tetrameric antibody complexes for blocking non-specific labeling of antigens A method for preventing or inhibiting non-specific binding reactions between a detection reagent and an antigen in an immunological assay is described. The method involves using tetrameric antibody complexes that can bind to the antigen and are comprised of two mono... | 11/14/2006 |
| 7135335 | Method for separating cells using immunorosettes The present invention relates to methods for separating cells using immunorosettes. The method involves contacting a sample containing nucleated cells and red blood cells with an antibody composition which allows immunorosettes of the nucleated cells and the red blo... | 11/14/2006 |
| 7071006 | Carrier holding micro-substances, system suspending such carriers apparatus for manipulating such carriers and method of controlling positions of such carriers Carriers hold remote-acting bodies which can be manipulated by a remote force, and also hold a micro-substance which is a target substance of an assay. The remote-acting bodies are manipulated in order to control the positions of the micro-substances, so as to execu... | 07/04/2006 |
| 6991776 | Intracorporeal medicaments for high energy phototherapeutic treatment of disease New intracorporeal radiodense medicaments and certain medical uses and methods for use of such high energy phototherapeutic medicaments for treatment of human or animal tissue are described, wherein a primary active component of such medicaments is a halogenated xan... | 01/31/2006 |
| 6991907 | Methods for the assay of troponin I and T and complexes of troponin I and T and selection of antibodies for use in immunoassays Antibodies and methods are described for the detection and quantitation of cardiac specific troponin I in samples. Cardiac-specific troponin isoforms exist in various forms in the blood, including free and complexed forms. By selecting antibodies that are insensitiv... | 01/31/2006 |
| 6939678 | Methods for the assay of troponin I and T and complexes of troponin I and T and selection of antibodies for use in immunoassays Assay systems and specialized antibodies for the detection and quantitation of troponin I and troponin T in body fluids as an indicator of myocardial infarction. Since troponin I and T exist in various conformations in the blood, the ratios of the monomeric troponin... | 09/06/2005 |
| 6884628 | Multifunctional polymeric surface coatings in analytic and sensor devices Multifunctional, polyionic copolymers with molecular architectures and properties optimized for specific applications are synthesized on/or applied to substrate surfaces for analytical and sensing purposes. The coatings are particularly useful for suppression of non... | 04/26/2005 |
| 6750326 | Method for separating cells using immunorosettes The present invention relates to methods for separating cells using immunorosettes. The method involves contacting a sample containing nucleated cells and red blood cells with an antibody composition which allows immunorosettes of the nucleated cells and the red blo... | 06/15/2004 |
| 6713256 | Fluorescent energy transfer mediated chemical activation (fetma) for the elucidation of the three-dimensional structure of biomacromolecules The present invention relates to a method for the selected chemical activation of photo-activatable cross-linker molecules around ligand binding pockets and fluorescent groups in macromolecules, especially biological macromolecules, by using fluorescent ligands of t... | 03/30/2004 |
| 6673562 | Differential immunoassay The invention provides assay methods and kits that in general measure the level of a first analyte in a sample reduced by the level of a second analyte present in the same sample. In one embodiment, where levels of a first analyte from a first source is d... | 01/06/2004 |
| 6579687 | Methods for the assay of troponin I and T complexes of troponin I and T and selection of antibodies for use in immunoassays Methods and compositions are described for the detection and quantitation of cardiac specific troponin I and troponin T in samples. Cardiac-specific troponin isoforms exist in various forms in the blood, including free and complexed forms. By selecting an... | 06/17/2003 |
| 6410251 | Method for detecting or assaying target substance by utilizing oxygen electrode A method for detecting or assaying one constituting member in a specific binding pair, for example, the antigen in an antigen/antibody pair, by utilizing specific binding such as binding between an antigen and an antibody, together with redox reaction for... | 06/25/2002 |
| 6331286 | Methods for high energy phototherapeutics Methods of treating and imaging diseased tissue having the steps of administering a radiosensitizer agent proximate to or into the diseased tissue; and treating the diseased tissue with x-rays or other ionizing radiation so as to activate the radiosensiti... | 12/18/2001 |
| 6303325 | Method for detecting analytes The invention relates to methods of determining the presence or amount of an analyte in a sample suspected of containing the analyte, said method comprising the steps of: (a) bringing together in an aqueous medium to form a mixture: (i) the sample; (ii) a... | 10/16/2001 |
| 6299876 | Cytotoxic drug therapy A compound comprises a target cell-specific portion, such as an antibody specific to tumor cell antigens, and an inactivating portion, such as an enzyme, capable of converting a substance which in its native state is able to inhibit the effect of a cytoto... | 10/09/2001 |
| 6235535 | Fluorescent energy transfer ligand interaction assay on a lipid film This invention relates to a fluorescence-based immunoassay method for the detection of an analyte, or for the measurement of its concentration in a biological sample. The method is based on the ability of a multivalent analyte to induce aggregation of rec... | 05/22/2001 |
| 6174686 | Methods for the assay of troponin I and T and complexes of troponin I and T and selection of antibodies for use in immunoassays Assay systems and specialized antibodies for the detection and quantitation of troponin I and troponin T in body fluids as an indicator of myocardial infarction. Since troponin I and T exist in various conformations in the blood, the ratios of the monomer... | 01/16/2001 |
| 6156521 | Methods for the recovery and measurement of troponin complexes The invention relates in part to methods and compositions for identifying the presence, measuring the amount, stabilizing, and facilitating recovery of troponin complexes or individual troponin isoforms in a sample.... | 12/05/2000 |
| 5851778 | Analyte assay using a trifunctional conjugate A trifunctional conjugate is provided having three chemical moieties attached through a spacer moeity. At least two of the chemical moieties are relatively small molecules, usually less than about 7,000 Daltons in size. The spacer moiety is selected to im... | 12/22/1998 |
| 5795725 | Methods for the assay of troponin I and T and selection of antibodies for use in immunoassays Assays and antibodies are disclosed for the detection and quantitation of cardiac specific troponin I and troponin T in body fluids as an indicator of myocardial infarction. Since troponin I and T exist in various conformations in the blood, the ratios of... | 08/18/1998 |
| 5736342 | Biosensor for detecting the presence of chosen analytes The present invention relates to a biosensor for detecting the presence of an analyte in solution. The biosensor is composed of: a) an ion channel receptor immobilized in a suspended lipid film which is in contact with an ion-containing solution on each side t... | 04/07/1998 |
| 5736341 | Methods and test kits for specific and sensitive diagnosing of periodontal diseases Methods and test kits are described which provide a reliable, sensitive and selective assessment of periodontal disease activity, peri-implantitis or HIV(+)-infection/AIDS-disease related periodontal diseases. The preferred methods and test kits are const... | 04/07/1998 |
| 5728519 | Assay for virulent revertants of attenuated live vaccines and kits therefor The present invention provides a method of classifying an unclassified live poliovirus vaccine as having an acceptable or unacceptable level of neurovirulence, comprising, prior to vaccine administration, the steps of: a) selectively amplifying a region o... | 03/17/1998 |
| 5661019 | Trifunctional conjugates A trifunctional conjugate is providing having three chemical moieties attached through a spacer moiety. At least two of the chemical moieties are relatively small molecules, usually less than about 7,000 Daltons in size. The spacer moiety is selected to i... | 08/26/1997 |
| 5658568 | Cytotoxic drug therapy A compound comprises a target cell-specific portion, such as an antibody specific to tumour cell antigens, and an inactivating portion, such as an enzyme, capable of converting a substance which in its native state is able to inhibit the effect of a cytot... | 08/19/1997 |
| 5601977 | Enzyme-catalyzed chemiluminescent detection of proteins and nucleic acids using hydroxyaryl cyclic diacylhydrazide compounds A method and test kit using a hydroxyaryl cyclic diacylhydrazide, a peroxide and a peroxidase enzyme on a blotting membrane for detecting DNA, RNA or proteins (polypeptides) is described. The method and kit provides enhanced chemiluminescence in an assay ... | 02/11/1997 |
| 5583004 | Direct detection of unexpected alloantibodies in the serum of prospective transfusion recipients using a new hemagglutination inhibition assay Human red blood cells with antigenic determinants recognized by unexpected alloantibodies are mixed with serum from the potential recipient. Following incubation, multivalent monoclonal IgM antibodies specific to the antigenic determinant present on the t... | 12/10/1996 |
| 5573920 | Antibodies, and methods for their use This invention relates to antibodies and is particularly, though not exclusively, concerned with diagnostic and therapeutic methods using monoclonal bi- or tri-specific antibodies. The invention also provides a method in which binding of a first antigen t... | 11/12/1996 |
| 5552298 | Enzyme-catalyzed chemiluminescence from hydroxyaryl cyclic diacylhydrazide compounds An assay method, compositions and test kits using a hydroxyaryl cyclic diacylhydrazide is described. A hydrogen peroxide and peroxidase enzyme. The preferred compositions incorporate enhancer compounds and a chelating agent which suppresses light producti... | 09/03/1996 |
| 5523210 | Bispecific antibody determinants A homogenous sample of identical bispecific antibody determinants, each determinant being composed of two L-H half-molecules linked by disulfide bonds, each L-H half-molecule being specific for a different antigenic determinant and including at least the ... | 06/04/1996 |
| 5502197 | Derivatized pyridinoline reagent A pyridinoline composition in which pyridinoline is derivatized specifically at its aliphatic hydroxyl group by a selected chemical group is disclosed. In various embodiments, the composition may be used as a standard for HPLC or immunoassay of pyridinoli... | 03/26/1996 |
| 5492840 | Surface plasmon resonance sensor unit and its use in biosensor systems Methods for functionalizing sensing surfaces to be used in systems for measuring simultaneously several properties of one biomolecule as well as for simultaneously measuring the concentrations of a plurality of biomolecules in a sample. The invention furt... | 02/20/1996 |
| 5413913 | Erythrocyte agglutination assay In an erythrocyte agglutination assay, the agglutination reagent comprises at least one erythrocyte binding molecule coupled to at least one specific analyte binding molecule wherein the erythrocyte binding molecule does not cause agglutination when incub... | 05/09/1995 |
| 5405753 | CMP-activated, fluorescing sialic acids, as well as processes for their preparation A process for preparing CMP-activated fluorescence indicator-labelled sialic acids is disclosed. According to the process, a 5-acylamido-9-amino-3,5,9-tridesoxy-ଲ-D-glycero-D-galactonoulosonic acid or 5-aminoacylamido-3,5-didesoxy-ଲ-D-glycero-... | 04/11/1995 |
| 5298401 | Process for the quantitative determination of the function and antigenic concentration of a substance contained in a biological liquid In a process for the quantitative determination of the function and antigenic concentration of a substance contained in a biological liquid, the substance is immobilized, the function is determined by the addition of a specific substrate which is then rem... | 03/29/1994 |
| 5292668 | Bispecific antibody determinants A homogenous sample of identical bispecific antibody determinants, each determinant being composed of two L-H half-molecules linked by disulfide bonds, each L-H half-molecule being specific for a different antigenic determinant and including at least the ... | 03/08/1994 |
