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| Number | Title | Issue Date |
| 7432107 | Cardiac hormones for assessing cardiovascular risk The present invention relates to the use of cardiac hormones, particularly natriuretic peptides, for diagnosing the cardiovascular risk of a patient who is a candidate for adminitstration of a cox-2-inhibiting compound, in particular an NSAID, selective cox-2 inhibi... | 10/07/2008 |
| 7410768 | Test methods and devices A method and test device for differentiating between states of an analyte that can exist in different forms, such as follicle stimulating hormone (FSH). The method or test device uses a pair of specific binding agents, especially monoclonal antibodies, in two assays... | 08/12/2008 |
| 7312069 | Method of analyzing ligand in sample and apparatus for analyzing ligand in sample A sample analyzing method capable of high-precision analysis without being affected by vibration and optical design is provided. In the sample analyzing method, a sample containing a ligand is caused to bind to a receptor that can bind specifically to the ligand, an... | 12/25/2007 |
| 7309611 | Prewetting stop flow test strip A test strip and method for detecting an analyte present in a sample. The test strip comprising: a buffer addition zone to which a buffer may be added; an absorbent zone proximal to the buffer addition zone; one or more test zones distal to the buffer addition zone,... | 12/18/2007 |
| 7229839 | Bidirectional lateral flow test strip and method A test strip adapted to receive a sample and detect an analyte therein is provided. The test strip comprises a sample addition zone to which a sample may be added; an absorbent zone proximal to the sample addition zone; one or more test zones distal to the sample ad... | 06/12/2007 |
| 7214531 | Pressure transduced chemical assay and method An assay system has a chamber that receives a test strip onto which a sample comprising an analyte has been placed. The chamber is in gaseous communication with a piezoelectric material that generates an electrical signal in response to a pressure change in the cham... | 05/08/2007 |
| 7205155 | Method for the determination of substances using the evanescence field method This invention relates to a method for the determination of substances using the evanescence field method. A cuvette, a microtiter well, a solution and a kit for application in a method according to the invention are disclosed. This method can in particular be used ... | 04/17/2007 |
| 7192779 | Diagnosis of Smith-Lemli-Optiz syndrome The invention provides a non-invasive assay for the detection of a SLOS affected individual by determining the ratio of at least one of the specific SLOS steroid analytes, dehydro-estriol (8-DHE3) and a dehydro-pregnanetriol (7-DHPT) to their normal steroid counterp... | 03/20/2007 |
| 7129096 | Sensor for use in testing biological, biochemical, chemical or environmental samples Disclosed are sensors for use in testing biological, biochemical, chemical or environmental samples, and methods of making and using the same. ... | 10/31/2006 |
| 7109042 | Assays An analytical test device useful for example in pregnancy testing, comprises a hollow casing (500) constructed of moisture-impervious solid material, such as plastics materials, containing a dry porous carrier (510) which communicates indirectly with t... | 09/19/2006 |
| 7091049 | Enhanced diffraction-based biosensor devices An enhanced diffraction based biosensor system and method are provided for detecting an analyte of interest in a test medium. The system incorporates at least one additional detection tag substance with the analyte of interest, the tag emitting a measurable paramete... | 08/15/2006 |
| 7083986 | Near infrared chemiluminescent acridinium compounds and uses thereof A method for the detection or quantitation of an analyte in a biological sample is disclosed. The method comprises the steps of selecting a biological sample suspected of containing a target analyte and binding the target analyte in the sample to a binding partner c... | 08/01/2006 |
| 7049152 | Color and shape changing polymeric ribbons and sheets The present invention herein provides the design, synthesis and characterization of compositions comprising asymmetric bolaamphiphilic lipids that form extended polymeric ribbons and wide sheets. These compositions may be doped, or interspersed, with various compoun... | 05/23/2006 |
| 7033775 | Simultaneous screening of multiple analytes Methods, compositions and kits are disclosed. The methods are directed to determining the presence of one or more analytes in a sample suspected of containing any one of a plurality of the analytes. A combination is provided comprising in a medium (i) the sample, (i... | 04/25/2006 |
| 6905886 | Preservative solutions This invention relates to preservative solutions for peptides, for example, parathyroid hormone, insulin-like growth factor binding protein 3 (IGFBP3), adrenocorticotropic hormone (ACTH) and mixtures thereof. Preferably, the peptides preserved by the solutions are n... | 06/14/2005 |
| 6818455 | Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents An analytical test device useful for example in pregnancy testing, comprises a hollow casing (500) constructed of moisture-impervious solid material, such as; plastics materials, containing a dry porous carrier (510) which communicates indirectly with ... | 11/16/2004 |
| 6808932 | Diagnosis of Smith-Lemli-Optiz syndrome The invention provides a non-invasive assay for the detection of a SLOS affected individual by determining the ratio of at least one of the specific SLOS steroid analytes, dehydro-estriol (8-DHE3) and a dehydro-pregnanetriol (7-DHPT) to their normal steroid counterp... | 10/26/2004 |
| 6797481 | Simultaneous screening of multiple analytes Methods, compositions and kits are disclosed. The methods are directed to determining the presence of one or more analytes in a sample suspected of containing any one of a plurality of the analytes. A combination is provided comprising in a medium (i) the sample, (i... | 09/28/2004 |
| 6787324 | Method and apparatus for detecting conception in animals The present invention provides antibodies which specifically bind early conception factor, which can be found in body fluids of animals including but not limited to the cow, cat, dog, horse, human, sheep, and pig. The invention provides methods for detecting concept... | 09/07/2004 |
| 6767708 | Stabilized aqueous steroid immunoassay standards Aqueous solutions of steroid compounds which have biological activity and have a tendency to oxidative degradation at temperatures between 2 and 8° C. on storage in excess of several months are stabilized by the addition of chelators. Aqueous solutions of particula... | 07/27/2004 |
| 6756233 | Method for measuring free ligands in biological fluids, and assay kits for measuring same A method for measuring free ligands in biological fluids in the presence of bound ligand and endogenous binding proteins, without disturbing the equilibrium between the free ligand and the protein-bound ligand, comprised of the following steps: (a) incubating a samp... | 06/29/2004 |
| 6720192 | Screening for analytes using labeled receptors A method for assaying an analyte in a sample. The method comprising the steps of a) contacting the sample with material comprising a receptor which is present in a liposome and which liposome comprises a detectable functionality, said contact occurring under conditi... | 04/13/2004 |
| 6689615 | Methods and devices for processing blood samples Approaches are described for separating plasma from whole blood samples and include the use of magnetically attractable particles associated with an agglutinating agent. The magnetically attractable particles bind the cellular components in a whole blood ... | 02/10/2004 |
| 6677123 | Process for detecting increased risk of fetal chromosomal abnormality An increased risk of a fetal chromosomal abnormality, for example, fetal Down syndrome can be detected by separating or discriminating -fetoproteins present in the body fluid of a pregnant woman, and measuring the proportion of one or more of the &... | 01/13/2004 |
| 6613583 | Electrochemiluminescent label based on multimetallic assemblies Electrochemiluminescent label compounds containing multimetallic centers separated by bridging ligands are described. An example of a multimetallic electrochemiluminescent label suitable for use in electrochemiluminescence (ECL) methods, [(bpy)2 | 09/02/2003 |
| 6610496 | Prediction of growth performance and composition in animals, including cattle, from response to growth hormone releasing hormone A method for predicting animal growth performance, which includes administering a suitable amount of growth hormone releasing hormone (GHRH) to an animal, observing levels of growth hormone (GH) subsequent to GHRH administration and; predicting growth and... | 08/26/2003 |
| 6548306 | Placental protein 13 The full amino acid and DNA sequences of placental protein 13 (PP13) are disclosed. Also described are various PP13 derived peptide fragments, and a recombinant method for the production of PP13. PP13 may be used in a screening and a diagnostic method for... | 04/15/2003 |
| 6528323 | Bidirectional lateral flow test strip and method A test strip adapted to receive a sample and detect an analyte therein is provided. The test strip comprises a sample addition zone to which a sample may be added; an absorbent zone proximal to the sample addition zone; one or more test zones distal to th... | 03/04/2003 |
| 6509462 | Estradiol derivative and immunoassy using the same The present invention provides a highly sensitive immunoassay system for estrogens, which utilizes as a labeled compound a biotinylated estradiol derivative of the formula (1) ##STR1## wherein one of R1 and R2 is hydrogen and the oth... | 01/21/2003 |
| 6492178 | Methods of determining an increased risk of a woman carrying a downs syndrome affected fetus by measuring an analyte in a biological sample There are provided methods for assaying biological specimens for one or more of leptin, prorenin or renin in order to provide predictive information about the likelihood of a woman carrying a Downs Syndrome affected fetus.... | 12/10/2002 |
| 6485982 | Test device and method for colored particle immunoassay Disclosed is a test cell and a method for detection of a preselected ligand in a liquid sample such as a body fluid. The test cell includes an elongate outer casing which houses an interior permeable material capable of transporting an aqueous solution an... | 11/26/2002 |
| 6429018 | Prenatal screening for Down's syndrome using hyperglycosylated gonadotropin A prenatal screening method for Down's syndrome involves assaying for hyperglycosylated gonadotropin in biological test samples such as urine, plasma or serum obtained from pregnant women. Hyperglycosylated gonadotropin comprises a variant population of c... | 08/06/2002 |
| 6395503 | Chemiluminescent reagents and chemiluminescence analysis methods with the use of the same The present invention provides a novel chemiluminescent reagent producing chemiluminescence in the presence of hydrogen peroxide, extent of which depends on peroxidase concentration, chemiluminescent analysis method using the same, in particular useful fo... | 05/28/2002 |
| 6387711 | Liquid intact parathyroid hormone (PTH) standards A solution of a non-reconstituted hormone and a preservative having a useful shelf life of at least six months, and, in some circumstances, at least a year. A series of solution of varying levels of the non-reconstituted hormone may be in a test kit and u... | 05/14/2002 |
| 6383766 | Reduced cortisol conjugates The present invention relates to compositions comprising novel reduced cortisol conjugates, methods for their preparation and use in immunoassays for cortisol. In another aspect, it relates to conjugates of reduced cortisol as immunogens or haptens for el... | 05/07/2002 |
| 6350579 | Extended dynamic range assays A method and compositions for the detection and/or quantification of an analyte through the use of a plurality of labeled probes, with two or more said probes targeted to different regions of said analyte. In specific embodiments, the labels are separatel... | 02/26/2002 |
| 6326209 | Measurement and quantification of 17 ketosteroid-sulfates as a biomarker of biological age The present invention provides an improved method for using the measurement of total urinary 17 KS-S, referred to herein as the urinary Anabolic/Catabolic Index (ACI), as part of a biomarker for biological age.... | 12/04/2001 |
| 6326159 | Receptors for immune complexes Receptors are disclosed that are antibodies that exhibit a binding affinity for an immune complex of a monoepitopic antigen and an antibody for such antigen that is substantially greater than the binding affinity for the monoepitopic antigen or the antibo... | 12/04/2001 |
| 6323321 | Antibody 97A6 The present invention relates to a monoclonal antibody binding an antigen on the megakaryocytic cell line UT-7. The invention further relates to hybridoma cells producing such an antibody.... | 11/27/2001 |
| 6300082 | Method and apparatus for measurement of the effect of test compounds on signal transduction at the level of biological receptors A method and apparatus for measuring binding between a plurality of molecules of a biological receptor protein and a plurality of molecules of a type which binds to said biological receptor is presented. Apparatus utilizes a sensor possessing a waveguide ... | 10/09/2001 |
