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"That the automobile has practically reached the limit of its development is suggested by the fact that during the past year no improvements of a radical nature have been introduced."
Scientific American ; Jan. 2 edition, 1909
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| Number | Title | Issue Date |
| 7374946 | Method for the detection of compounds comprising methylenedioxyphenyl Process and a test kit for the detection of drugs of methylenedioxy amphetamine family and derivatives, are disclosed. The process comprises (a) sampling sufficient amount of a material, suspected to be examined comprise of said methylenedioxyphenyl group; (b) admix... | 05/20/2008 |
| 7247502 | Hapten-carrier conjugates for treating and preventing nicotine addiction Novel hapten-carrier conjugates are capable of inducing the production of antibodies, in vivo, that specifically bind to nicotine. These conjugates comprise a nicotine hapten conjugated to an immunogenic carrier protein. The novel conjugates preserve the chirality o... | 07/24/2007 |
| 7238533 | Personal illicit drug detection method Personal illicit drug detecting apparatus is disclosed which includes a substance chemically reactive to a suspected drug. The substance is provided in the form of a layer positioned on at least one finger of a user. The substance can be blended into finger nail pol... | 07/03/2007 |
| 7148070 | Diagnostic detection method The present invention relates to a diagnostic test kit and method for detecting the presence of certain metabolic by-products in human urine. The kit includes a test strip with an exposed face side containing chemical reagents which react in the presence of selected... | 12/12/2006 |
| 7091049 | Enhanced diffraction-based biosensor devices An enhanced diffraction based biosensor system and method are provided for detecting an analyte of interest in a test medium. The system incorporates at least one additional detection tag substance with the analyte of interest, the tag emitting a measurable paramete... | 08/15/2006 |
| 7060505 | Assay device An assay device and method are provided which allow the determination of the presence or absence of at least one analyte in a test sample, while providing specific identification of the test subject. The assay device includes a reaction medium having at least one re... | 06/13/2006 |
| 6949344 | Hair analysis method A method the direct analysis of an analyte in keratinized structures, e.g., hair and fingernails, which comprises preparing a mixture containing a low redox potential activator compound such as dithiothreitol or dithioerythritol, an enzyme suitable for the digestion... | 09/27/2005 |
| 6818452 | Lateral flow contact test apparatus A test strip assembly for detecting the presence of a substance in liquid sample comprises a contact detection pad in communication with a reagent-free absorbent strip. The absorbent strip receives the liquid sample and communicates it to the contact detection pad v... | 11/16/2004 |
| 6797481 | Simultaneous screening of multiple analytes Methods, compositions and kits are disclosed. The methods are directed to determining the presence of one or more analytes in a sample suspected of containing any one of a plurality of the analytes. A combination is provided comprising in a medium (i) the sample, (i... | 09/28/2004 |
| 6702988 | Automatic on-site drug testing system and method A system and method for on-site drug testing rapidly and objectively performs a drug screen on a urine sample at a collection center. The system includes a plurality of collection centers, wherein each collection center includes a test station for perform... | 03/09/2004 |
| 6645776 | Electrical excitation of label substances at insulating film-coated conductors The excitation of label molecules usable in chemical and biochemical analysis by electrical pulses at electrodes covered with a thin insulating film, and the use of such electrodes in chemical, clinical and biochemical analysis. The electrodes include a c... | 11/11/2003 |
| 6613583 | Electrochemiluminescent label based on multimetallic assemblies Electrochemiluminescent label compounds containing multimetallic centers separated by bridging ligands are described. An example of a multimetallic electrochemiluminescent label suitable for use in electrochemiluminescence (ECL) methods, [(bpy)2 | 09/02/2003 |
| 6602892 | Methods for nicotine replacement dosage determination A method for predicting nicotine replacement dosage to achieve a target nicotine serum concentration relies on measuring blood nicotine concentration prior to smoking cessation. At least two values corresponding to other patient characteristics, such as b... | 08/05/2003 |
| 6558956 | Method and apparatus for detection of a controlled substance Techniques and devices for detecting and analyzing controlled substances and the like are discussed including highly reactive sensor molecules which are coated on a spectroscopic sample surface (4) and which may chemically react with a given analyte to fo... | 05/06/2003 |
| 6534325 | Immunoassay for the detection of amphetamines, methamphetamines and methylenedioxy designer amphetamines The present invention provides an immunoassay method for the highly sensitive detection of amphetamines, methamphetamines, and methylenedioxy designer amphetamines in urine samples. Commercially available reagents for the determination of amphetamines and... | 03/18/2003 |
| 6472227 | Barbiturate assay, tracers, immunogens, antibodies and kit The present invention is directed to a fluorescence polarization immunoassay for barbiturates, to the various components needed for preparing and carrying out such an assay, and to methods of making these components. Specifically, tracers, immunogens and ... | 10/29/2002 |
| 6472228 | Composition and methods for synthesis of novel tracers for detecting amphetamine and methamphetamine in samples This invention relates to novel tracers and their synthesis and use in an immunoassay for the detection of controlled drugs such as amphetamine (APM), methamphetamine (MAPM) and their derivatives, in a biological or aqueous sample. In particular, this inv... | 10/29/2002 |
| 6461873 | Caffeine detector The caffeine detector uses a paper chromatographic technique to measure the concentration of caffeine in a beverage. The device includes a well or other receptacle for containing a predetermined test volume of the beverage. A paper strip is suspended so t... | 10/08/2002 |
| 6406922 | Device for the testing of body fluid samples A drug of abuse test kit for testing low volumes of a fluid sample having a transparent flat bag container for retaining a fluid sample to be tested and the open end of the container has a recloseable closure. The container is maintained in a substantiall... | 06/18/2002 |
| 6403383 | Diagnostic test kit for immunological assays of fluid samples A diagnostic test kit has a cup-like container for retaining a fluid sample to be tested and the open top end of the container is closed by a closure cap on the open end. There is a slit in the closure cap to receive a multiple test card having a pluralit... | 06/11/2002 |
| 6391261 | Device for detecting analytes related to sample pH A device for measuring, concurrently from the same sample solution, the pH and presence or quantity of an analyte in the solution. The pH and analyte measuring sections of the invention are contained within the same holding structure.... | 05/21/2002 |
| 6352863 | Assay device An assay device and method are provided which allow the determination of the presence or absence of at least one analyte in a test sample, while providing specific identification of the test subject. The assay device includes a reaction medium having at l... | 03/05/2002 |
| 6350582 | Hair analysis method A method for the direct analysis of the presence of an analyte which becomes embedded in keratinized structures, e.g., hair, fingernails and toenails, from the bloodstream of a subject which comprises preparing a mixture containing dithiothreitol or dithi... | 02/26/2002 |
| 6251690 | Electrical excitation of label substances at insulating film-coated conductors The excitation of label molecules usable in chemical and biochemical analysis by electrical pulses at electrodes covered with a thin insulating film, and the use of such electrodes in chemical, clinical and biochemical analysis. The electrodes include a c... | 06/26/2001 |
| 6228658 | Method of using a test strip for the immunochemical detection of substances A test strip for the immunochemical detection of substances after sampling from surfaces, with a conjugate zone (2) located between an eluent application zone (1) at one end of the test strip and a reaction zone (3) at the opposite end, the zones being in... | 05/08/2001 |
| 6174688 | Multiassay method for determining the concentrations of antigens and interferants A method of determining the concentration of a sample antigen in the presence of an interferant by (1) running two immunoassays on the sample: one assay where the interferant influences the binding of both the sample antigen and a labeled antigen and a se... | 01/16/2001 |
| 6165800 | Chemiluminescent energy transfer conjugates and their uses as labels in binding assays A new class of chemiluminescent acridinium or benzacridinium compounds is disclosed by virtue of forming an intramolecular energy transfer conjugate (ETC) between the acridinium or benzacridinium compound and a luminophore. A method of extending the emiss... | 12/26/2000 |
| 6156272 | Method and apparatus for urine self-test intended for use in a toilet A method and apparatus for urine self testing wherein the apparatus is placed directly into the toilet after urination which avoids the direct placement and retention of an apparatus in the stream of urine as is common with urine testing devices. The appa... | 12/05/2000 |
| 6124136 | Method of monitoring compliance with methadone treatment program A method of monitoring compliance of a patient that has been placed on a methadone maintenance program by determining plasma methadone concentration from urine methadone concentration. An unadulterated urine sample is obtained from the patient. The urine ... | 09/26/2000 |
| 6066505 | Fluorescence polarization immunoassay In a fluorescence polarization assay for determining the amount of a target analyte in a test sample, wherein the amount of analyte is related to the amount of fluorescence emitted from the analyte-containing reagent medium, the improvement comprising con... | 05/23/2000 |
| 6025200 | Method for remote detection of volatile taggant A method of tagging and detecting objects is disclosed which comprises the steps of: (a) applying a volatile taggant to the object; and (b) subsequently detecting the presence of the taggant by the absorption, transmittance, reflectance, photon emission o... | 02/15/2000 |
| 6022693 | Hair analysis method A method for the direct analysis of the presence of an analyte which becomes embedded in keratinized structures, e.g., hair, fingernails and toenails, from the bloodstream of a subject which comprises preparing a mixture containing dithiothreitol or dithi... | 02/08/2000 |
| 5981298 | Immunoassay device and method A device and related method for performing one or more immunoassays to detect the presence of respective analytes in a sample. The device involves the use of a unitary bibulous material providing one or more flow paths having a common origin site and a pl... | 11/09/1999 |
| 5976895 | Device for the collection, testing and shipment of body fluid samples A drug abuse test kit has a transparent cup-like container for retaining a fluid sample to be tested and the open top end of the container is closed by an inner closure insert seated within the open end. There is a slit in the inner closure insert to rece... | 11/02/1999 |
| 5849599 | Method for making a preconjugate A method for making a preconjugate which includes immunogenic species of a polymorphic analyte. The method is carried out by reacting an activated binding moiety, and a polymorphic analyte at room temperature for between about 10 hours and about 60 hours.... | 12/15/1998 |
| 5846703 | Fluorescence immunoassays using fluorescent dyes free of aggregation and serum binding Fluorescence immunoassays methods are provided which use fluorescent dyes which are free of aggregation and serum binding. Such immunoassay methods are thus, particularly useful for the assay of biological fluids, such as serum, plasma, whole blood and ur... | 12/08/1998 |
| 5840588 | Agglutination inhibition assay methods and reagents for psychoactive substances Immunoassays of psychoactive drugs including psychotomimetic drugs, narcotic drugs, and tetrahydrocannabinols and treatment methods based on the antigenic properties of protein conjugates of these drugs. These methods are based upon treating the psychoact... | 11/24/1998 |
| 5747352 | Reagents and methods for the rapid and quantitative assay of pharmacological agents Bidentate reagents for rapidly and quantitatively assaying the concentration of pharmacological agents in biological samples are described. The reagents are used in an immunoassay format for determining the concentration of desired, preselected pharmacolo... | 05/05/1998 |
| 5710005 | Analyte detection with a gradient lateral flow device Methods for determining the concentration of an analyte in a sample in which an analyte gradient is established and brought into contact with one or more zones that contain binding members that interact with the analyte and thereby produce a detectable si... | 01/20/1998 |
| 5707872 | Nicotine and/or nicotine metabolite detection A solid phase capable of detecting the presence of nicotine and/or nicotine metabolites is described. The solid phase is impregnated with assay reagents including a color determinant, a buffer, a cyanogen releasing agent and a cyanogen halide forming agen... | 01/13/1998 |
