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Patent No. 5205055

Pneumatic Shoe Lacing Apparatus

This invention provides a pneumatic shoe lacing apparatus for the pneumatic lacing of shoe.

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Class 436/811 - TEST FOR NAMED DISEASE, BODY CONDITION OR ORGAN FUNCTION


Subclass of Class 436 - Chemistry: analytical and immunological testing
Definition: Art collection related to antigen-antibody test for a named
No. of patents: 815
Last issue date: 12/27/2011


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NumberTitleIssue Date
7161034Lidocaine analogs and methods of making and using same
Lidocaine analogs, latex particle-analog conjugates, and methods of making and using the same. The analogs have the formula: wherein Z comprises a nucleophilic group and optiona...
01/09/2007
7148071Quantitative, high-throughput screening method for protein stability
In proteomic research, it is often necessary to screen a large number of polypeptides for the presence of stable structure. Described herein are methods (referred to as MALDI MS-HX and SUPREX) for measuring the stability of proteins in a rapid, high-throughput fashi...
12/12/2006
7148025Method of detecting native proBNP
The present invention relates to antibodies specifically binding to native proBNP, a method for specific detection of native proBNP, a method of correlating the level of native proBNP to the diagnosis of heart failure, a kit for detection of native proBNP and to a h...
12/12/2006
7144705Diagnostic assay for stroke
Heart and brain fatty acid binding proteins (H-FABP, B-FABP) are markers for stroke. The invention provides a diagnostic assay for either of these markers, preferably by ELISA using anti-H-FABP or B-FABP antibody. Since H-FABP is also a marker for acute myocardial i...
12/05/2006
7138237Diagnosis, prevention and treatment of Crohn's disease using the OmpC antigen
The present invention provides a method of diagnosing Crohn's disease in a subject by determining the presence or absence of IgA anti-OmpC antibodies in the subject, where the presence of the IgA anti-OmpC antibodies indicates that the subject has Crohn's disease.
11/21/2006
7138239Method and reagent for testing for multiple organ failure in SIRS by cytochrome C measurement
A method for testing for multiple organ failure in SIRS, which comprises determining cytochrome C in body fluid and using the determined result as an index of the multiple organ failure, and a reagent for testing for multiple organ failure in SIRS, which comprises a...
11/21/2006
7109044Method of detection and disease state management for renal diseases
The present invention relates to a method of detection of an early-stage renal disease, comprising determining the concentration of human lipocalin-type prostaglandin D synthase in a body fluid sample taken from a subject and comparing the determined concentration w...
09/19/2006
7101682Simultaneous screening of multiple analytes
Methods, compositions and kits are disclosed. The methods are directed to determining the presence of one or more analytes in a sample suspected of containing any one of a plurality of the analytes. A combination is provided comprising in a medium (i) the sample, (i...
09/05/2006
7087435Biopolymer marker indicative of disease state having a molecular weight of 2753 daltons
The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopoly...
08/08/2006
7081348Immunoassay of human medullasin and diagnosis of multiple sclerosis using the same
There is provided an immunoassay by which the amount of human medullasin present inside granulocytes, which are one leukocyte component in blood, can be determined with high accuracy and with good reproducibility. Also provided is an immunoassay of medullasin, where...
07/25/2006
7081347Method for predicting cardiovascular events
A method for assessing aspirin resistance and relative risk of a cardiovascular event in a patient taking aspirin is provided. The concentration of 11-dehydro-thromboxane B2 in a urine sample is measured and compared to a set of standardized quartile concentrations....
07/25/2006
7074576Protein biopolymer markers indicative of alzheimer's disease
The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopoly...
07/11/2006
7070760Skin test for schizophrenia
A diagnostic method for assaying schizophrenia in a subject is provided wherein a preparation comprising platelet derived proteins or fractions thereof having a pI above about 6.5 is injected into a subject and the occurrence of delayed type hypersensitivity (DTH) r...
07/04/2006
7056745Diagnostic method and apparatus
Diagnostic method, based on the amounts of biogenic amines that are contained in a body fluid or other sample. A number of measured parameters related to the desired diagnostic information are derived from the amounts. For each diagnostic information desired, an inp...
06/06/2006
7049152Color and shape changing polymeric ribbons and sheets
The present invention herein provides the design, synthesis and characterization of compositions comprising asymmetric bolaamphiphilic lipids that form extended polymeric ribbons and wide sheets. These compositions may be doped, or interspersed, with various compoun...
05/23/2006
7033775Simultaneous screening of multiple analytes
Methods, compositions and kits are disclosed. The methods are directed to determining the presence of one or more analytes in a sample suspected of containing any one of a plurality of the analytes. A combination is provided comprising in a medium (i) the sample, (i...
04/25/2006
7033836Mastitis detection method
The invention relates to a method for detecting mastitis in an animal, characterized by the steps of collecting milk from the animal, and assaying the milk for a substance produced in the animal in an anaerobic environment, and comparing the substance levels obtaine...
04/25/2006
7026132Method of monitoring the effect of Cathepsin S inhibitors
The present invention relates to a method for monitoring the effect of in vivo administration of Cathepsin S inhibitors by measuring accumulation of an intermediate degradation product of invariant chain (Ii), in particular the p10 Ii fragment, in blood of dosed sub...
04/11/2006
7015048Methods and kits for diagnosing or monitoring synovial or osteoarticular disease, comprising the use of a specific marker for synovial tissue degradation
Disclosed are specific markers for synovial tissue degradation and methods of using the markers in diagnosing, monitoring or determining a prognosis of synovial disease. ...
03/21/2006
7015044Diagnostic for early stage Alzheimer's disease
A method for diagnosing Alzheimer's disease even at early stages by assessing the levels of sulfatides or its metabolites in biological fluids is disclosed. ...
03/21/2006
7008613Quaternary ammonium compounds
A compound of formula corresponding to either formula (Ia) or (Ib): wherein: M represents a molecule that can be used for the treatment or diagnosis of pathologies caused by attack on the cartilage, ...
03/07/2006
7008800Biopolymer marker indicative of disease state having a molecular weight of 1077 daltons
The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopoly...
03/07/2006
6998243Biopolymer marker indicative of disease state having a molecular weight of 1793 daltons
The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopoly...
02/14/2006
6998242Method of diagnosing metabolic bone diseases
A method of diagnosing metabolic bone diseases, especially osteoporosis and arthrosis characterized by determining the concentration of osteoclastgenesis inhibitory factor (OCIF) in humor. Monoclonal antibodies recognizing equally both of monomer type and dimer type...
02/14/2006
6991907Methods for the assay of troponin I and T and complexes of troponin I and T and selection of antibodies for use in immunoassays
Antibodies and methods are described for the detection and quantitation of cardiac specific troponin I in samples. Cardiac-specific troponin isoforms exist in various forms in the blood, including free and complexed forms. By selecting antibodies that are insensitiv...
01/31/2006
6989239Methods for diagnosis and treatment of chronic immune diseases
Methods are provided for diagnosing/characterizing chronic immune disease activity in a subject. In the subject methods, a sample is obtained from a subject suspected of having or known to have a chronic immune disease. The sample is then assayed for the presence an...
01/24/2006
6989278Method of identifying therapeutic compounds for a treatment of hepatic disorders
The present invention relates to methods of identifying potentially therapeutic compounds for the treatment of hepatic disorders, preferably alcohol-induced hepatitis. Further, use of mammals in such methods, therapeutic compounds identified using said methods and t...
01/24/2006
6989240Method for detecting hemolysis
This invention provides a method for determining the presence of hemolyzed erythrocytes in blood by detecting erythrocyte adenylate kinase in a serum sample from the blood. This invention also provides a method for diagnosing a hemolytic condition in a subject suspe...
01/24/2006
6986995Methods of diagnosing liver fibrosis
The present invention provides a method of diagnosing the presence or severity of liver fibrosis in an individual by detecting α2-macroglobulin (α2-MG) in a sample from the individual; detecting hyaluronic acid (HA) in a sample from the individual; detecting tissu...
01/17/2006
6974706Application of biosensors for diagnosis and treatment of disease
A method for detecting compounds of interest in bodily fluids, including exhaled breath and blood. The present invention uses biosensors that mimic naturally occurring cellular mechanisms, including RNA oligonucleotide chains or “aptamers,” in combination with m...
12/13/2005
6951759Detection of bacterial vaginosis
There is disclosed a method for detecting the presence of bacterial vaginosis in a female subject comprising the steps of: obtaining a sample from the vaginal region of the subject; detecting acetic acid present in...
10/04/2005
6951763Detection of antibodies to glycosphingolipids using solid-phase reactants coated with carbonyl groups
Methods of detecting antibodies to one or more glycosphingolipid(s) of interest in a sample are disclosed which comprise using a solid-phase reactant having carbonyl groups attached theron, and the glycosphingolipid(s) of interest linked to the solid-phase reactant ...
10/04/2005
6951730Method for rapidly diagnosing upper respiratory conditions
A method for detecting upper respiratory conditions. The method includes implementation of a device upon which are fixed discrete indicators of pH, protein content, nitrite content and/or leukocyte esterase activity. ...
10/04/2005
6951716Anti-platelet immunoglobulin bead positive control
Immunoassay methods and apparatus are provided which utilize flow cytometry, coated latex microspheres, and fluorochrome labeled antibodies, to simultaneously detect the presence and amount of one or more analytes in a sample. Beads of several different sizes, color...
10/04/2005
6946260Allergen/inflammatory testing and diagnosis
The invention relates to the use of a secretor variant cell-line expressing the alpha moiety of human IgE binding protein to determine the allergic status of a given individual. Moreover, the cell-line is also used to provide an assay system for determining the alle...
09/20/2005
6939716Method for detecting conditions indicative of sepsis
The disclosure describes a method for detecting conditions indicative of sepsis. In one embodiment of the invention, an increase in the level of 3-chlorotyrosine or 3-bromotyrosine from the normal level in a sample of body fluid or tissue is indicative of early seps...
09/06/2005
6939678Methods for the assay of troponin I and T and complexes of troponin I and T and selection of antibodies for use in immunoassays
Assay systems and specialized antibodies for the detection and quantitation of troponin I and troponin T in body fluids as an indicator of myocardial infarction. Since troponin I and T exist in various conformations in the blood, the ratios of the monomeric troponin...
09/06/2005
6936476Point of care diagnostic systems
Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and operating rooms, or in any situation in which a rapid and accurate res...
08/30/2005
6933106Platelet immunoglobulin bead suspension and flow cytometry
Immunoassay methods and apparatus are provided which utilize flow cytometry, coated latex microspheres, and fluorochrome labeled antibodies, to simultaneously detect the presence and amount of one or more analytes in a sample. By combining FALS and fluorescence, it ...
08/23/2005
6913936Immunological test kit comprising an immunologically invisible peg copolymer conjugated to one or more immunologically reactive substances
A novel compound comprising an immunologically invisible polyethylene glycol copolymer is used to carry one or more immunologically reactive substances. The novel compounds may be used as part of kits for immunological assays. ...
07/05/2005
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