Did You Know...
...that several people are credited with the invention of the flush toilet? Most people have heard of Thomas Crapper (1837-1910), the sanitary engineer who invented the valve-and-siphon arrangement that made the modern toilet possible. Another claimant to "the throne" was British inventor Alexander Cumming who patented a toilet in 1775. Then there's a nameless Minoan (a native of ancient Crete) who lived 4,000 years ago who supposedly was ahead of his time and created the first flush toilet!
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| Number | Title | Issue Date |
| 6893816 | Microfabricated, flowthrough porous apparatus for discrete detection of binding reactions An improved microfabricated apparatus for conducting a multiplicity of individual and simultaneous binding reactions is described. The apparatus comprises a substrate on which are located discrete and isolated sites for binding reactions. The apparatus is characteri... | 05/17/2005 |
| 6884592 | Devices for analyte concentration determination and methods of manufacturing and using the same Test strips for determining the concentration of at least one analyte, e.g., glucose, in a physiological sample and methods for their manufacture and use and are provided. The subject test strips include a transfer element for facilitating the transfer of sample to ... | 04/26/2005 |
| 6881578 | Analyte concentration determination meters and methods of using the same Devices and methods for determining the concentration of an analyte in a physiological sample are provided. The subject devices are meters characterized by having an internal structure that includes a test strip selecting element having a continuously reduced cross-... | 04/19/2005 |
| 6875578 | System for cell-based screening The present invention provides systems, methods, screens, reagents and kits for optical system analysis of cells to rapidly determine the distribution, environment, or activity of fluorescently labeled reporter molecules in cells for the purpose of screening large n... | 04/05/2005 |
| 6844162 | Assays for TSH receptor autoantibodies A method and kit for monitoring autoantibodies to thyroid stimulating hormone (TSH) receptor in a sample of body fluid, which employs the steps of: (i) incubating TSH receptor with a sample of body fluid; (ii) reac... | 01/18/2005 |
| 6844165 | Retentate chromatography and protein chip arrays with applications in biology and medicine This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity conditions, and detecting the analytes retained on the substrate by d... | 01/18/2005 |
| 6833111 | Multiple analyte assaying device with a multiple sample introduction system A multiple analyte assaying device includes a casing having a pocket portion adapted to capture or contain a predetermined volume of fluid specimen to be assayed. Disposed within the casing is a sample receiving pad and one or more reagent test strips. The pocket po... | 12/21/2004 |
| 6827899 | Test device A test device for testing of analyte concentration in a fluid comprises: a housing (2) having an opening and containing a stack of sensors (16); a transport member (4) rotatably mounted in the opening of the housing, having an axis of rotation w... | 12/07/2004 |
| 6812038 | Assay device and use thereof A test device and a kit for conducting an assay for the determination of an analyte in a sample comprises (i) a housing (1,2), and within said housing, (ii) a flow matrix (6) allowing liquid to be transported by capillary action and having at least one... | 11/02/2004 |
| 6808889 | Method and device for detection of Apo A, Apo B and the ratio thereof in saliva A method has been developed to detect the levels of apolipoproteins A-1 and B in saliva, which is correlated with the levels of HDL and LDL in serum, respectively. In unstimulated saliva, the ration of Apo A to Apo B is correlated with the ration of HDL to LDL in se... | 10/26/2004 |
| 6794150 | Assay for YKL-40 as a marker for degradation of mammalian connective tissue matrices The invention is a method of identifying the presence of, and monitoring, a disease state in a mammal which is associated with degradation of connective tissue in the mammal. The method detects and determines whether diagnostically or prognostically significant leve... | 09/21/2004 |
| 6770490 | Membrane immunobead assay for the detection of ciguatoxin and related polyether marine toxins An immunological test kit suitable for the rapid detection of ciguatoxin and related low molecular weight lipid polyether marine toxins in fish tissues in the field, home or laboratory. The test procedure utilizes a synthetic membrane laminated onto one end of a sol... | 08/03/2004 |
| 6764856 | Semen detection system and method The present invention is directed to a system and method for detecting the presence of semen on material. The system includes a solution of sodium phosphate, maleic acid, dye fast blue salt, naphthyl acid phosphate and deionized water, together with a solution dispe... | 07/20/2004 |
| 6762033 | Method for determining the fertility of mammals, especially humans Disclosed is a method for determining the fertility of mammals, in particular of humans, wherein a body or organ fluid is taken from a mammal, the afamin content is determined in this body or organ fluid, and the determined afamin content is com... | 07/13/2004 |
| 6753190 | Immunologic test method and immunologic test kit The present invention relates to an immunological detection method capable of performing detection of an analyte in a test sample, and a kit used therefor. There is provided an immunological detection method for detecting an analyte by using a water-absorbent substr... | 06/22/2004 |
| 6743640 | Fluorescent polymer-QTL approach to biosensing A chemical composition including a moiety comprising a quencher (Q), a tethering element (T), and a ligand (L) that associates with and quenches a fluorescent polymer is disclosed. When an analyte sample is introduced, the ligand (L) binds to a target biological age... | 06/01/2004 |
| 6727072 | EGF-r detection kit A kit containing the reagents necessary for the qualitative or quantitative demonstration of epidermal growth factor receptor (EGFR) in formalin-fixed, paraffin-embedded tissue sections. A immunohistochemical staining procedure is employed which utilizes a primary m... | 04/27/2004 |
| 6723524 | Immunoassay method and kit An immunoassay, e.g. ELISA, method and kit for determining (preferably quantitatively) an analyte adsorbed at a surface or present in a liquid sample, comprising binding the analyte to a solid phase, attaching a marker to the analyte, and detecting marker attached t... | 04/20/2004 |
| 6716410 | Reagents and methods for diagnosing, imaging and treating atherosclerotic disease The invention provides a novel human Mab Fab, cloned by phage display, and its use in diagnostic and therapeutic methods. In particular the invention provides a method for analyzing the OxLDL components of atherosclerotic plaques in vivo and a means to determine the... | 04/06/2004 |
| 6716641 | Dipstick for carbohydrate-free transferrin assay The invention relates to a new dipstick assay for detecting and quantifying the content of an target analyte in a sample. The assay is particularly useful for example in the diagnosis and monitoring of alcoholism by the detection of asialo transferrin or carbohydrat... | 04/06/2004 |
| 6709633 | Disposable devices for testing body fluids A self-contained disposable device to be used in testing a body fluid, particularly urine. The device is in the form of a 3-ply composite comprising an intermediate ply and outer plies on opposite sides thereof. The intermediate ply has a cavity for retaining a test... | 03/23/2004 |
| 6689617 | Agent for detecting malondialdehyde, method of making the same, and test kit for use thereof A reagent for use in detecting the presence of aldehyde particularly in an aqueous solution, urine, or other body fluids comprising a solution sodium metabisulfite, phosphoric acid, basic fuchsin (BA 130) and deionized water. The sodium metabisulfite is p... | 02/10/2004 |
| 6682897 | Peptides derived from human heat protein 60 for treatment of diabetes, compositions, methods and kits Novel peptides which are epitopes of the human 60 kDa heat shock protein (hsp60) may be used for the diagnosis and treatment of insulin-dependent diabetes mellitus (IDDM). Pharmaceutical compositions containing such peptides and kits for use in diagnosis ... | 01/27/2004 |
| 6680202 | Method for concurrent and sequential multi-step reactions for producing a plurality of different chemical compounds The present invention is a method and an apparatus to provide a dynamic matrix system for synthesizing a plurality of chemical compounds simultaneously, i.e. in parallel, and to synthesize a series of plurality of simultaneously synthesized chemical compo... | 01/20/2004 |
| 6649414 | Microparticles with multiple fluorescent signals and methods of using same This invention provides a novel fluorescent particle including a core or carrier particle having on its surface a plurality of smaller polymeric particles or nanoparticles, which are stained with different fluorescent dyes. When excited by a light source ... | 11/18/2003 |
| 6638716 | Rapid amperometric verification of PCR amplification of DNA Rapid electrochemical verification of the amplification of DNA by a polymerase chain reaction in a small sample of the PCR product.... | 10/28/2003 |
| 6638480 | High sensitivity test system for the colorimetric determination of specific gravity or total dissolved solids in aqueous samples A highly sensitive and convenient test method, composition and device for the facile calorimetric determination of total dissolved solids in an aqueous sample having a low specific gravity is presented. The reagent composition comprises the mixture of a c... | 10/28/2003 |
| 6632681 | Reagent delivery device and method of use A device and method for filtering a biologically derived sample and for mixing the sample with a reagent, comprising a fluid container defining a reservoir compartment and including a container outlet, a filter and a fluid flow-through matrix disposed in ... | 10/14/2003 |
| 6623979 | System for collecting and locally analyzing a fluid specimen A method and apparatus for collecting a fluid specimen, locally analyzing the specimen to qualitatively detect specified chemical components at concentrations above threshold levels, and providing machine readable test results for facilitating data collec... | 09/23/2003 |
| 6596502 | Kit and method for detecting fecal parasites The invention concerns a home kit and a method for detection of the presence of a fecal parasite in a stool.... | 07/22/2003 |
| 6589731 | Method for detecting biological agents A sensor element is provided including a polymer exhibiting a measurable property from the group of luminescence and electrical conductivity, the polymer being complexed with a unit including a recognition element, a tethering element and a property-alter... | 07/08/2003 |
| 6579684 | Assay of YKL-40 as a marker for cancer This invention is a method of identifying the presence of, and monitoring, a disease state in a mammal which is associated with degradation of connective tissue in the mammal. The method detects and determines whether diagnostically or prognostically sign... | 06/17/2003 |
| 6558911 | Sperm quality assay The present invention relates to male infertility, and in particular to assays for predicting fertility in animals including human and bovines. In some embodiments, semen samples are evaluated by measuring the amount of ubiquitin in the sample, and in par... | 05/06/2003 |
| 6558959 | Analytical assay device and methods using surfactant treated membranes to increase assay sensitivity An analytical device comprising a surfactant-treated porous reaction membrane having an exposed sample-contacting surface and at least one receptor area located in a limited region of the exposed sample-contacting surface. The limited region has a higher ... | 05/06/2003 |
| 6548654 | DNA encoding mammalian CX3C chemokine genes Nucleic acids encoding a new family of chemokines, the CX3 C family, from a mammal, reagents related thereto, including specific antibodies, and purified proteins are described. Methods of using said reagents and related diagnostic kits are als... | 04/15/2003 |
| 6548309 | Procedure for assay of liquids containing undissolved solids, semisolids or colloids In qualitative or quantitative assays which employ a test device comprising a test strip pretreated for detection of a specified target analyte dissolved in a liquid medium, the presence of solid, semisolid and/or colloidal materials in the liquid medium ... | 04/15/2003 |
| 6544796 | System for producing multiple diagnostic test elements A system for producing multiple diagnostic test elements has a support (1) with an analytical region (3) to which diagnostic test spots (8) are applied, one or several stop edges (11-13) for each direction in space for positioning the support, a first hol... | 04/08/2003 |
| 6541267 | Methods for testing oxidative stress Method and compositions for determining oxidative stress in a subject are provided in which presence of an aldehyde in a biological fluid is correlated with an oxidative stress in a subject. A test reagent having a pH regulator, a reducing agent, and an a... | 04/01/2003 |
| 6534282 | Detection of hypertension using immunoreactive metabolic products A method to assess hypertension by measuring the amount of free and conjugated hydroxyeicosatrienoic acids (DHETs) and metabolites of DHETs, which are metabolites of arachidonic acid (AA) epoxygenases and epoxide hydrolases, in a biological sample which c... | 03/18/2003 |
| 6534323 | Compositions and methods for early detection of heart disease The invention relates to methods, compositions, kits, and devices for detecting cardiac ischemia, hypoxia, or other causes of heart failure in a mammal by obtaining a test sample from a mammal, measuring a level of a non-polypeptidic cardiac marker in the... | 03/18/2003 |
