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| Number | Title | Issue Date |
| 8119423 | Device and method for multiple analyte detection The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurali... | 02/21/2012 |
| 7439079 | Assay devices having detection capabilities within the hook effect region A lateral flow assay device for detecting the presence or quantity of an analyte within a test sample is provided. The device utilizes multiple zones, one of which serves as an indicator of whether or not the analyte in the test sample is within the “hook effectâ€... | 10/21/2008 |
| 7413880 | Test kit for immunochromatography A test kit for immunochromatography comprising a test strip and a test tube is described. The test strip comprises a detection zone for detecting an analyte in a sample. The test tube accommodates the test strip. The test tube comprises an indicator at a position co... | 08/19/2008 |
| 7390675 | Multi-functional and configurable assay Novel magnetic assay methods and systems. According to a preferred embodiment, a chromatographic medium is provided that is designed to be contacted with a test solution having activated magnetic particles such that the solution flows bilaterally thereacross. A magn... | 06/24/2008 |
| 7384794 | Micro-devices and analytical procedures for investigation of biological systems Fibres with an extraction phase coated thereon in combination with a positioning device are described to perform adsorption of components of interest from an animal or animal tissue for the investigation of living systems. A number of interfaces to analytical instru... | 06/10/2008 |
| 7381570 | Device and method for multiple analyte detection The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurali... | 06/03/2008 |
| 7381571 | Device and method for analyte detection The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurali... | 06/03/2008 |
| 7381569 | Device and method for multiple analyte detection The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurali... | 06/03/2008 |
| 7374951 | System and apparatus for use in detecting microorganisms A system and an apparatus for use in detecting a target microorganism or agent is disclosed which involves a solid support carrying a binding partner specific for the particular microorganism or agent and the solid support being characterised in that it defines mean... | 05/20/2008 |
| 7368294 | Method for optical detection of an adjoining of a material component to a sensor material with the aid of biological, chemical or physical interaction and device for carrying out said method (variants) Method for detecting biological or chemical components in liquid or gas is based on measuring changes of the sensor layer thickness due to binding reactions. A plate or a gap with two surfaces of a solid optical material is used as the sensor layer. The surfaces are... | 05/06/2008 |
| 7364921 | Method and apparatus for separating biological materials and other substances A method for separating biological materials and other substances is disclosed, wherein a mixture containing desired and undesired components are exposed to magnetic particles having ligands capable of binding to the desired and/or the undesired components to form a... | 04/29/2008 |
| 7354614 | Diagnostic device A diagnostic device 1 for performing an immunochromatographic analysis of a sample is disclosed. The diagnostic device 1 comprises a porous substrate 10 for performing the analysis and a pre-filter 30 to remove solid components, such as s... | 04/08/2008 |
| 7354776 | Method of processing and testing powdered samples using immunochromatographic strip tests A method and kit for processing and testing powdered samples are provided herein. The powdered sample is combined with a fluid to produce a slurry or liquid suspension, and the slurry is contacted with an immunochromatographic test strip containing detectable reagen... | 04/08/2008 |
| 7319032 | Non-sugar sweeteners for use in test devices The present invention provides methods, compositions, and kits for rapid detection of analytes in a sample. Surprisingly, it has been found that bulking materials having non-sugar sweeteners effectively enhance chromatographic detection methods by providing componen... | 01/15/2008 |
| 7309614 | Self-referencing biodetection method and patterned bioassays The invention relates to compositions and methods for detecting biomolecular interactions. The detection can occur without the use of labels and can be done in a high-throughput manner. The invention further relates to self-referencing colorimetric resonant optical ... | 12/18/2007 |
| 7309611 | Prewetting stop flow test strip A test strip and method for detecting an analyte present in a sample. The test strip comprising: a buffer addition zone to which a buffer may be added; an absorbent zone proximal to the buffer addition zone; one or more test zones distal to the buffer addition zone,... | 12/18/2007 |
| 7303924 | Method of functionalising solid supports The invention relates to: a method of functionalizing solid supports; the functionalized solid supports thus obtained; and the use thereof, in particular for the immobilization of biological molecules, such as nucleic acids, polypeptides, lipids, carbohydrates and h... | 12/04/2007 |
| 7288413 | Combined chemical and immunochemical fecal occult blood test Methods for testing a fecal sample for the presence of hemoglobin, comprising performing a chemical fecal occult blood test on the sample and then performing an immunochemical fecal occult blood test on a portion of the sample exposed to the chemical reagents used i... | 10/30/2007 |
| 7276367 | Method of etching islands of cells in a grid pattern An apparatus and process for monitoring migratory cell proliferation with restricted migration on a substrate includes providing a substrate, coating the substrate with extracellular matrix, plating cells suspended in cell culture media on extracellular matrix, and ... | 10/02/2007 |
| 7270995 | Analyzing device The present invention is an analytical device which comprises a porous piece assembly consisting of a liquid reagent-receiving porous piece (1), a labeled substance-retaining piece (2), a test piece (3) comprising a detection site (4) and... | 09/18/2007 |
| RE39816 | Conjunctive analysis of biological marker expression for predicting cardiac mortality A diagnostic tool is disclosed for accurately and rapidly diagnosing the condition of an ailing organ. Although applicable to numerous organ and organ systems, this application particularly illustrates the concept of conjunctive marker utilization as it relates to d... | 09/04/2007 |
| 7252938 | Methods and devices for producing a polymer at a location of a substrate Methods and devices for producing a polymer at a location of a substrate are provided. In the subject methods, a fluid droplet containing a first monomer labeled with a first detectable label is deposited from a fluid deposition device onto a location of a substrate... | 08/07/2007 |
| 7244622 | Device and method for multiple analyte detection The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurali... | 07/17/2007 |
| 7244396 | Method for preparation of microarrays for screening of crystal growth conditions A method of screening solution conditions suitable for the crystallization of macromolecules with a picogram to a microgram of protein using picoliter or nanoliter volumes is provided. A preferred method comprises preparing a plurality of recipe solutions in millili... | 07/17/2007 |
| 7241418 | Method for immobilizing conjugates in diagnostic tests The invention concerns a method for the detection of an analyte in a sample using analyte-specific conjugates which have at least one heterologous group for an analyte-independent binding to a control zone. The present invention additionally provides new conjugates ... | 07/10/2007 |
| 7241626 | Isolation and confirmation of analytes from test devices Methods, articles, and kits for obtaining elevated concentrations of a substance from a sample that has become bound, for example by providing a positive test result in an immunoassay or other binding assay. The concentrated substance is optionally subjected to furt... | 07/10/2007 |
| 7235406 | Nucleic acid analysis device The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality ... | 06/26/2007 |
| 7232689 | Calibration procedure for investigating biological systems Use of calibrant in extraction phase is described for quantification of components of interest in samples in laboratory application as well as in on-site monitoring. This approach is particularly useful for in-vivo investigation of living systems. ... | 06/19/2007 |
| 7226793 | Method for adding an apparent non-signal line to a lateral flow assay A test device and method for determining the presence or absence of an analyte in a fluid sample, the test device including a support bearing a mark thereon, and a matrix defining an axial flow path. In operation, an observation area in the test device becomes trans... | 06/05/2007 |
| 7211443 | Device and method for multiple analyte detection The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurality ... | 05/01/2007 |
| 7179657 | Method for adding an apparent non-signal line to a rapid diagnostic assay A test device and method for determining the presence or absence of one or more analytes in a fluid sample, the test device including a support or member bearing a mark thereon, and a matrix or member containing a capture zone. In operation, an observation area in t... | 02/20/2007 |
| 7097981 | Reaction wells, assembly thereof, immunoassay apparatus and method using such well assemblies The present invention relates mainly to reaction vessels, to sets of such vessels for automatic immunological assay apparatuses, to automatic immunological assay apparatuses making use of such sets of vessels, and to a method implementing sets of such vessels. Accor... | 08/29/2006 |
| 7060448 | Evaluating binding affinities by force stratification and force panning The present invention is a method for selectively removing objects from a surface utilizing a probe. The probe is scanned over the surface utilizing a greater and greater relative amount of force so that a certain number of the objects are removed from the surface. ... | 06/13/2006 |
| 7056746 | Array cytometry A method and apparatus for the manipulation of colloidal particulates and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution. Light-controlled electrokinetic assembly of particles near surfaces relies on t... | 06/06/2006 |
| 7056657 | Apparatus and methods for magnetic separation Separation apparatus and method for separating magnetic and/or magnetically-labeled particles from a test medium. Test medium within a reaction chamber is caused to flow past a collecting surface, and a high-gradient magnetic field is applied to the surface t... | 06/06/2006 |
| 7052858 | Diagnostic assays for detection of This invention provides a novel Cryptosporidium parvum protein disulfide isomerase polypeptide, and nucleic acids that encode this polypeptide. The invention also provides methods, reagents, and kits that are useful for diagnosing infection by Cryptosporid... | 05/30/2006 |
| 7045363 | Nucleic acid-bound polypeptide method of producing nucleic acid-bound polypeptide and immunoassay using the polypeptide A nucleic acid-bound polypeptide produced by binding a nucleic acid to a polypeptide, a method of producing the nucleic acid-bound polypeptide, and applications of the nucleic acid-bound polypeptide, including immunoassays for an antigen or antibody, such as an aggl... | 05/16/2006 |
| 7041509 | High throughput screening assay systems in microscale fluidic devices The present invention provides novel microfluidic devices and methods that are useful for performing high-throughput screening assays. In particular, the devices and methods of the invention are useful in screening large numbers of different compounds for their effe... | 05/09/2006 |
| 7018830 | Device and method for the detection of an analyte utilizing mesoscale flow systems Disclosed are devices for detecting the presence of a preselected analyte in a fluid sample. The devices comprise a substrate microfabricated to define a sample inlet port, and a mesoscale flow system that includes a sample flow channel extending from the inlet port... | 03/28/2006 |
| 7008799 | Analytical test element with a capillary channel The invention concerns an analytical test element for the determination of an analyte in a liquid containing an inert carrier, a detection element and a channel capable of capillary liquid transport which has a sample application opening at one end and a vent openin... | 03/07/2006 |
