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| Number | Title | Issue Date |
| 8153436 | Assays for disease-associated crystals in biological samples Methods of assaying for disease-associated crystal species in biological samples are described. Such methods involve contacting a patient sample with an excess of a detectable crystal-tagging compound reactive with a plurality of crystal species under conditions tha... | 04/10/2012 |
| 8003394 | Methods for metal assays using optical techniques An improved optical method for determining metal or a metal compound thereof in a sample with organic impurities. The optical method comprises of solvating the metal in a liquid medium and then mixing this liquid medium with an optical indicator and then measuring t... | 08/23/2011 |
| 7964409 | Detecting hypocalcemia using bovine nose sweat The invention is collecting nose sweat and testing the nose sweat for levels of calcium. Testing may be done using standard laboratory procedures for calcium detection, or may be done cow-side using a suitable test for calcium levels, such as a water hardness test k... | 06/21/2011 |
| 7767461 | Apparatus and method for measuring concentrations of scale-forming ions This invention relates to methods and apparatus for determination of ion concentrations, particularly in downhole water from hydrocarbon wells, aquifers etc. It is useful in a wide range of applications, including predicting the formation of scale and fingerprinting... | 08/03/2010 |
| 7544516 | Reagent for determination of calcium and determination method A method for determination of calcium in a sample derived from a living body, by the reaction of calcium in the sample with Chlorophosphonazo-III or a compound analogous thereto in the presence of vanadate ions, followed by determination of calcium in the sample on ... | 06/09/2009 |
| 7419637 | Oxides of manganese processed in continuous flow reactors Methods and systems for regenerating and pretreating oxides of manganese and precipitation of oxides of manganese from manganese salt solutions. Oxides of manganese, a slurry containing oxides of manganese or manganese salt solutions are mixed with heated aqueous ox... | 09/02/2008 |
| 7416893 | Methods for diagnosing drug-resistant cancer cells or for identifying chemotherapeutic agents by measuring anomalous intracellular ion and/or second messenger dynamics The present invention relates to methods of identifying drug-resistant and/or drug-sensitive cells, for example, breast cancer and brain tumor cells, on the basis of different ion and/or second messenger dynamics between a drug-sensitive and drug-resistant cell. For... | 08/26/2008 |
| 7407626 | Composition and method of use of medical test kit A medical test kit includes a glucose testing composition, a protein testing composition, a bilirubin testing composition, a bilinogen testing composition, an amylase testing composition, a blood testing composition, a calcium testing composition, a nitrite testing ... | 08/05/2008 |
| 7399639 | Sensors, and methods of making and using the same The present invention is directed, in part, to sensors for detecting metal ions, and methods of making and using the same. ... | 07/15/2008 |
| 7312611 | Apparatus and method for trapping bead based reagents within microfluidic analysis systems The present invention provides an on-chip packed reactor bed design that allows for an effective exchange of packing materials such as beads at a miniaturized level. In accordance with the present invention, there is provided a method of concentrating an analyte wit... | 12/25/2007 |
| 7297547 | Analysis of metals in acidic solutions In one embodiment, a method of neutralizing the matrix of an acidic solution including at least one metal using a weak anion exchange resin is provided. The method includes the acts of: activating the weak anion exchange resin with a weakly acidic metal complexing r... | 11/20/2007 |
| 7288414 | Use of phosphonazo III for the measurement of calcium, magnesium and sodium in analytical samples Novel reagent formulations and methods are described for the use of phosphonazo III to measure calcium, magnesium and sodium in biological fluids. ... | 10/30/2007 |
| 7275418 | Method for the quantitative detection of two contaminants in a fluid The quantitative determination of two contaminants of a fluid is carried out in the following steps: detection of permittivity ε and viscosity v of the fluid; determination of the quantity of the first contaminant 11e on the basis of a difference betw... | 10/02/2007 |
| 7254490 | Marking system and method A methodology for facilitating the identification, authentication or quality control of packaged products is described comprising a marking and an authentication phase. In the marking phase the method involves obtaining an analytical specification, and for example a... | 08/07/2007 |
| 7247489 | Ion-detecting microspheres and methods of use thereof This invention provides methods of using ion-detecting microspheres containing an ionphore and a chromoionphore in clinical laboratory instrumentation such as flow cytometry for sample analysis. In one embodiment, the microspheres are contacted with a flowing stream... | 07/24/2007 |
| 7241623 | Lithium detection in liquid biological samples and reagents therefor A method of detecting soluble lithium in a liquid biological sample comprising combining: (a) an amount of the biological sample; (b) 2,3,7,8,12,13,17,18-octobromo-5,10,15,20-tetrakis(4-sulphonatophenyl) porphyrin; (c) alkali; (d) detergent; (e) chelating agent; and... | 07/10/2007 |
| 7226563 | Ion-detecting sensors comprising plasticizer-free copolymers Plasticizer-free ion-detecting sensors for detecting a target ion in a sample are provided. The sensor comprises a plasticizer-free copolymer comprised of polymerized units of methacrylate monomers and a polymerizable ion exchanger, wherein the methacrylated monomer... | 06/05/2007 |
| 7220383 | Method and instrument for automated analysis of fluid-based processing systems An analytical apparatus to monitor fluid systems has at least one extraction module having a raw-sample reservoir connected by input fluid conduit to individual ones of said fluid systems, to extract raw samples for analysis from said fluid systems, one or more modi... | 05/22/2007 |
| 7214538 | Device and method for the determination of lithium ion concentration in a biological fluid The present invention relates to a novel device and method for the detection of lithium ions in a biological fluid. In a preferred embodiment, the present invention provides a novel compound and a optical sensor which incorporates said compound for the detection of ... | 05/08/2007 |
| 7208121 | Plasticizer-free-ion-detective sensors A plasticizer-free ion detective sensor for detecting a target ion in a sample is provided. The sensor comprises a copolymer of methacrylate monomers with pendant alkyl groups of different length, and an ionophore for detecting the target ion. The copolymer matrix o... | 04/24/2007 |
| 7201876 | Ion-detecting sensors comprising plasticizer-free copolymers Ion-detecting sensors for detecting a target ion in a sample are provided. The sensor comprises a plasticizer-free copolymer comprised of polymerized units of methacrylate monomers having pendent alkyl groups of different length and a functionalized ionophore of sai... | 04/10/2007 |
| 7202090 | Hardness measurement reagent To provide a hardness measurement reagent unaffected by an M alkalinity in hardness measurement. A hardness measurement reagent as a one-solution type reagent includes a dye chosen from Eriochrome Black T (EBT) and Calmagite, triethanolamine, a glycol compound, and ... | 04/10/2007 |
| 7198955 | Method and apparatus for measurement of blood substitutes A method is disclosed whereby the concentration of a blood substitute, such as cross-linked hemoglobin, in a serum or plasma specimen is rapidly and accurately identified and quantified. The method further takes the measured concentration of the blood substitute and... | 04/03/2007 |
| 7168288 | Hydrogen sulfide generator for sensor calibration The present invention relates to the use of internally-generated hydrogen sulfide as a calibration gas for hydrogen sulfide sensors. The present invention also relates to an apparatus and methods for self-calibration of hydrogen sulfide sensors. ... | 01/30/2007 |
| 7150997 | Multiplexed active biologic array A method of addressing and driving an electrode array includes the step of addressing one or more electrodes within the array using a plurality of row and column lines. In one aspect of the method, a value corresponding to a voltage is stored in a local memory assoc... | 12/19/2006 |
| 7129093 | Quantitative method of determining beryllium or a compound thereof in a sample A method of determining beryllium or a beryllium compound thereof in a sample, includes providing a sample suspected of comprising beryllium or a compound thereof, extracting beryllium or a compound thereof from the sample by dissolving in a solution, adding a fluor... | 10/31/2006 |
| 7125660 | Nucleic acid sensor molecules and methods of using same Methods for engineering a nucleic acid sensor molecule are provided. Biosensors comprise a plurality of nucleic acid sensor molecules labeled with a first signaling moiety and a second signaling moiety. The nucleic acid sensor molecules recognizes target molecules w... | 10/24/2006 |
| 7109043 | Fluorescent probe for magnesium ion determination A fluorescent probe for measuring magnesium ion, which can selectively form a complex with magnesium ion in aqueous system is disclosed. The fluorescent probe for measuring magnesium ion according to the present invention has the structure represented by the followi... | 09/19/2006 |
| 7101717 | Addressable biologic electrode array An addressable biologic electrode array includes an array of electrodes disposed on a support, the array of electrodes being selectively addressed and driven using a memory associated with each electrode of the array, the driven electrodes being driven at one of a p... | 09/05/2006 |
| 7067320 | Sensor for luminescense-optical determination of an analyte The invention relates to an optochemical sensor functioning in accordance with the FRET-principle and exhibiting an acceptor (chromophore or luminophore) responsive to an analyte contained in a sample medium as well as a donor (luminophore), characterized in that ac... | 06/27/2006 |
| 7045097 | Biologic electrode array with integrated optical detector A biologic electrode array is formed on a semiconductor substrate. A matrix of electrode sites is disposed on the semiconductor substrate. A matrix of optical detectors is disposed beneath the electrode sites in the semiconductor substrate, wherein each electrode si... | 05/16/2006 |
| 6994973 | Method and agent for determining total water hardness The invention relates to a dry chemical method and a test strip for determining calcium and magnesium in aqueous samples. Said test strip contains o-cresolphthalein complex (o-CPC; CAS Registry No. 2411-89-4) as a colour-causing reagent in a buffer system with a pH ... | 02/07/2006 |
| 6902700 | Method and device for testing aldehyde in polyester polymer A test strip, methods for making and using the test strip, and a kit are described, which allow for the simple and efficient determination of the acetaldehyde content in a polyester polymer. The strip and methods have application, for example, in the manufacture of ... | 06/07/2005 |
| 6875615 | Sensors for the determination of organometallic compounds The present invention relates to sensors for the determination of organometallic compounds comprising the following elements: a) an inorganic, organic or polymeric support, insoluble in the sample to analyze b) an indicator which reversibly reacts with... | 04/05/2005 |
| 6867048 | Multiplexed active biologic array A method of addressing and driving an electrode array includes the step of addressing one or more electrodes within the array using a plurality of row and column lines. In one aspect of the method, a value corresponding to a voltage is stored in a local memory assoc... | 03/15/2005 |
| 6846299 | Method for continuous recirculating peritoneal dialysis Method for a continuous recirculating peritoneal dialysis wherein the peritoneal dialysis fluid is infused into a peritoneal cavity of a patient and then, typically on a continuous process basis a portion of the dialysis fluid is sequentially drained from the cavity... | 01/25/2005 |
| 6821786 | Diagnostic test for elemental imbalances A self-diagnostic test, a self-diagnostic test apparatus, and method of manufacturing a self-diagnostic test for screening for elemental mineral imbalances in a patient utilizing an analysis of the reaction of mineral specific reagents to a sample from a patient are... | 11/23/2004 |
| 6812034 | Fetuin-MGP-mineral complex in serum assayed to determine calcification risk This invention provides methods of inhibiting calcification of a soft tissue (e.g., an artery, a heart valve, an atherosclerotic plaque, a cancer, a kidney, a prostate, skin, muscle, cartilage, viscera, and heart muscle) in a mammal. These methods involve inhibiting... | 11/02/2004 |
| 6806089 | Low frequency modulation sensors using nanosecond fluorophores Described is a new approach to fluorescence sensing based on a mixture of fluorophores, one of which is sensitive to the desired analyte. If a long lifetime analyte-insensitive fluorophore is mixed with a short lifetime analyte-sensitive fluorophore, the modulation ... | 10/19/2004 |
| 6790664 | Fluorometric monitoring and control of soluble hardness of water used in industrial water systems A method of monitoring and controlling hardness in an industrial water system is described and claimed. The method requires the use of a Compound that develops a separate detectable fluorescent signal in the presence of soluble hardness. A fluorometer is used to det... | 09/14/2004 |
