Did You Know...
...that after Parker Brothers executives turned down the game of Monopoly because it had "52 fundamental errors" (including taking too long to play), a copy of the game wound up in the home of the company president who stayed up until 1 a.m. to finish playing it? He was so impressed by the game that the next day he wrote to inventor Charles Darrow and offered to buy it!
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| Number | Title | Issue Date |
| 8444932 | D-dimer, troponin, and NT-proBNP for pulmonary embolism The present invention relates to a method of diagnosing acute pulmonary embolism (PE) in a subject including a) determining the amount of fibrin-fibrinogen degradation products, in particular D-dimer in a sample of the subject; b) determining the amount of a natriur... | 05/21/2013 |
| 8426209 | Methods and apparatus for sorting cells using an optical switch in a microfluidic channel network Apparatus and Methods are provided for a microfabricated fluorescence activated cell sorter based on an optical switch for rapid, active control of cell routing through a microfluidic channel network. This sorter enables low-stress, highly efficient sorting of popul... | 04/23/2013 |
| 8404487 | Magnetic resonance spectroscopy of breast biopsy to determine pathology, vascularization and nodal involvement Robust classification methods analyse magnetic resonance spectroscopy (MRS) data (spectra) of fine needle aspirates taken from breast tumors. The resultant data when compared with the histopathology and clinical criteria provide computerized classification-based dia... | 03/26/2013 |
| 8377392 | Immunoassay device with improved sample closure An apparatus and method for sealing a fluid sample collection device, comprising loading a fluid sample collection device with a fluid sample, said device comprising a housing having at least one substantially planar surface that includes an orifice in fluid communi... | 02/19/2013 |
| 8361412 | Cell measuring and sorting chip A cell sorting device using an inexpensive chip capable of being exchanged for each sample. The chip includes: a first flow path allowing buffer fluid containing cells to flow down; second and third flow paths which put the first flow path therebetween and allow buf... | 01/29/2013 |
| 8323885 | Homeobox gene An isolated nucleic acid molecule comprising the nucleotide sequence set forth in SEQ ID NO: 1. ... | 12/04/2012 |
| 8309360 | Reagent for analyzing urine and method for analyzing urine A reagent for analyzing urine is described. The reagent comprises a fungus membrane damaging agent for damaging a cellular membrane of yeast-like fungus in urine; a first dye for staining yeast-like fungus so that a fluorescent intensity of damaged yeast-like fungus... | 11/13/2012 |
| 8304246 | Methods for the diagnosis of dementia and other neurological disorders The present invention is directed to a method for differentially diagnosing dementia or the risk of dementia in a patient. The method comprises obtaining a sample from the patient; analyzing the sample to obtain quantifying data for one or more than one metabolite m... | 11/06/2012 |
| 8303906 | Test element for analyzing body fluids An analytical test element for determining an analyte in a body fluid comprises a detection area in which the analyte is detected and an application site at which the body fluid can be applied to the test element. The application site is spaced apart from the detect... | 11/06/2012 |
| 8304245 | Microfluidic flow lysometer device, system and method The invention provides a device, system and method that enables a microfluidic flow lysometer cell analyzer. Using a population of suspended living cells. cell surface molecule detection reagents, and cell cytoplasm (or nuclear) molecule detection reagents, this mic... | 11/06/2012 |
| 8293536 | Reagent, reagent kit and analyzing method A method for analyzing platelet is described. In the method, a measurement sample is prepared by mixing a sample and a dye for staining platelet. The dye is selected from the group consisting of Capri blue, Nile blue and brilliant cresyl blue. By irradiating cells i... | 10/23/2012 |
| 8283176 | Method of pre-treatment and staining of a biological sample and device for support of a biological sample and methods of using such device There is disclosed a method of pre-treatment and staining, according to a protocol, of a biological sample disposed upon the surface of a carrier, the method comprising the step of recording at least one parameter relating to at least one protocol step in a non-vola... | 10/09/2012 |
| 8283177 | Fluidic system with washing capabilities for a flow cytometer A method for cleaning a fluidic system of a flow cytometer having a sheath pump to pump sheath fluid towards an interrogation zone and a waste pump to pump the sheath fluid and a sample fluid as waste fluid from the interrogation zone, wherein the sheath pump and/or... | 10/09/2012 |
| 8273574 | Apparatus and methods for conducting assays and high throughput screening The present invention provides microfluidic devices and methods for using the same. In particular, microfluidic devices of the present invention are useful in conducting a variety of assays and high throughput screening. Microfluidic devices of the present invention... | 09/25/2012 |
| 8263408 | Method to characterize blood and red blood cells via erythrocyte membrane fragility quantification A method for quantifying the quality degradation of individual stored red blood cell (RBC) units, thereby yielding information to improve decisions regarding their respective allocation, patient suitability, and use. The method comprises: a hemolysis step; an optica... | 09/11/2012 |
| 8263407 | Method for non-contact particle manipulation and control of particle spacing along an axis Method and system for uniformly spacing particles in a flowing system comprising suspending particles in an elongated fluid filled cavity; exposing said cavity to an axial acoustic standing wave field, wherein said axial acoustic standing wave field drives said part... | 09/11/2012 |
| 8241914 | EPI-damage apparatus and methods for sorting particles A method and apparatus for sorting stained particles in a fluid stream, each of the method and apparatus including an epi-illumination optics system with a focusing lens. The optics system being operable to direct a beam of electromagnetic radiation through the focu... | 08/14/2012 |
| 8227250 | Lysing reagent, cartridge and automatic electronic cell counter for simultaneous enumeration of different types of white blood cells The present invention relates to a lysing reagent for use in the simultaneous automatic electronic enumeration and volumetric discrimination of different types of blood cells, such as leukocytes, thrombocytes, etc, in blood. Further, the present invention relates to... | 07/24/2012 |
| 8216848 | Means and method for diagnosing diabetes The present invention relates to a method for diagnosing diabetes or a predisposition thereof, comprising determining at least one metabolite in a test sample of a subject suspected to suffer from diabetes or to have a predisposition therefor and comparing the metab... | 07/10/2012 |
| 8216847 | Means and method for predicting diabetes The present invention relates to a method for diagnosing a predisposition for diabetes, comprising determining a metabolite in a test sample of a subject suspected to have a predisposition for diabetes and comparing the metabolite to a reference to diagnose the, pre... | 07/10/2012 |
| 8206987 | Photo-damage method for sorting particles A system and method for sorting a mixture of stained particles in a fluid flow path, including stained particles from two distinguishable groups. The system and method can include an electromagnetic radiation source for exciting fluorescence emissions from the stain... | 06/26/2012 |
| 8206986 | Methods for detecting Alzheimer's disease Markers are provided that are predictive of Alzheimer's disease. Levels of these markers, when different from a standard, are indicative of a patient being at risk of having or developing Alzheimer's disease. ... | 06/26/2012 |
| 8206988 | Method and apparatus for orienting sperm in a fluid stream A flow cytometry nozzle and method for orienting sperm cells in a fluid flow path including an interior surface of a nozzle. The interior surface of the nozzle having a first, a second and a third axially tapered region for progressively accelerating the speed of a ... | 06/26/2012 |
| 8206989 | Method of generating a dosing schedule using gamma secretase notch biomarkers The present invention relates to the biomarker TFF-3 that measures γ-secretase mediated Notch processing. TFF-3 has utility in predicting and/or determining in vivo Notch-related toxicity associated with inhibition of Notch processing mediated by γ-secretase. The ... | 06/26/2012 |
| 8206922 | Methods of detecting charcot-marie tooth disease type 2A Methods are described for screening a subject for risk of Charcot-Marie-Tooth Disease Type 2A or for diagnosing Charcot-Marie-Tooth disease or a predisposition for developing Charcot-Marie-Tooth disease in a subject, by detecting the presence or absence of a mutatio... | 06/26/2012 |
| 8198093 | Methods for sorting particles A method of sorting stained particles in a flow cytometer by generating a mathematical model based upon extracted features of waveform pulses produced in response to the stained particles. Waveform pulses can then be analyzed to determine the probability the stained... | 06/12/2012 |
| 8198092 | Digital sampling apparatus and methods for sorting particles A system and method for sorting a mixture of stained particles including a digital signal processor for analyzing and classifying the digital information generated from the particles and providing a sorting signal to a sorting system as a function of the analyzed an... | 06/12/2012 |
| 8192994 | Method of applying a biological specimen to an analytic plate A method applying a biological specimen to an analytic plate by using an applicator device to apply a coating to the analytic plate and adhering the biological sample to the plate. The coating is substantially transparent, translucent or invisible, and is substantia... | 06/05/2012 |
| 8187888 | Fluidic system for a flow cytometer The fluidic system of the preferred embodiment includes a sheath pump to pump sheath fluid from a sheath container into an interrogation zone and a waste pump to pump waste fluid from the interrogation zone into a waste container. The sheath pump and/or the waste pu... | 05/29/2012 |
| 8173432 | Method and system for characterization and mapping of tissue lesions The present invention provides a method and an apparatus for the in vivo, non-invasive, early detection of alterations and mapping of the grade of these alterations, caused in the biochemical and/or in the functional characteristics of epithelial tissues during the ... | 05/08/2012 |
| 8163560 | Coated test elements The invention concerns coated test elements and in particular test elements comprising a capillary gap which have a hydrophobic structured coating at least in the area surrounding the capillary gap. ... | 04/24/2012 |
| 8158434 | Method for performing counts within a biologic fluid sample A method for enumerating cellular elements and particulates within a biologic fluid sample is provided. According to one aspect of the invention, the method includes the steps of: a) providing a chamber formed between a first planar member that is transparent and a ... | 04/17/2012 |
| 8053190 | Susceptibility genes for age-related maculopathy (ARM) on chromosome 10q26 Allelic variations in the genes PLEKHA1 and LOC387715 are identified herein as risk factor for Age Related Maculopathy (ARM). A method is therefore provided for identifying a risk of development of ARM in an individual that comprises identification of allelic variat... | 11/08/2011 |
| 8026102 | Apparatus and method to characterize blood and red blood cells via erythrocyte membrane fragility quantification The present disclosure describes an apparatus and associated method for quantifying the quality degradation of individual stored red blood cell (RBC) units, thereby yielding information to improve decisions regarding their respective allocation, patient suitability,... | 09/27/2011 |
| 8017402 | Fluidic system for a flow cytometer The fluidic system of the preferred embodiment includes a sheath pump to pump sheath fluid from a sheath container into an interrogation zone and a waste pump to pump waste fluid from the interrogation zone into a waste container. The sheath pump and/or the waste pu... | 09/13/2011 |
| 7993927 | Histology methods Described are methods of visualizing biological samples using histological staining and invisible light (e.g., infrared or near-infrared) fluorescence. ... | 08/09/2011 |
| 7993928 | Detection of blood plasma Danshensu and Salvianolic acid B dissipating blood stasis botanical A detection method of blood plasma danshensu and salvianolic acid B of dissipating blood stasis botanical is disclosed. The method includes: (1) pretreating mammalian plasma sample: applying the plasma with medicine to small column of Waters Oasis HLB activated by m... | 08/09/2011 |
| 7989208 | Gamma secretase notch biomarkers The present invention relates to the biomarker TFF-3 that measures γ-secretase mediated Notch processing. TFF-3 has utility in predicting and/or determining in vivo Notch-related toxicity associated with inhibition of Notch processing mediated by γ-secretase. The ... | 08/02/2011 |
| 7989207 | Testing lumenectomy samples for markers of non-vascular diseases Lumenectomy material is tested to determine the presence or likelihood of a condition of a patient. The lumenectomy material is in the form of at least one continuous tissue strand collected in vivo from an inner surface of a body lumen of the patient. The presence ... | 08/02/2011 |
| 7989209 | Methods of chromogen separation-based image analysis Methods for chromogen separation-based image analysis are provided, with such methods being directed to quantitative video-microscopy techniques in cellular biology and pathology applications. ... | 08/02/2011 |
