Bizarre Patents
Combination Beverage Container and Spittoon
A combination beverage container and spittoon includes a bottom portion including outer wall and a first inner wall defining a spittoon space.
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| Number | Title | Issue Date |
| 6277586 | Cloned glutamic acid decarboxylase The invention provides cDNA molecules comprising a part of the cDNA sequence of GAD65 which encode at least one epitope for autoantibodies to GAD65. The invention also provides cloning vehicles capable of replication and expression c... | 08/21/2001 |
| 6277559 | Histamine measuring apparatus and a histamine measuring method Histamine may be quantitatively measured by performing the following steps. First, an oocyte that expresses histamine receptors is held in a recess formed at the bottom of a vessel. Then, first and second electrodes are inserted into the oocyte. Subsequen... | 08/21/2001 |
| 6268223 | Assay for detecting damage to the central nervous system A method is disclosed for the rapid diagnosis of disorders characterized by an ischemic event, such as stroke, transient ischemic attack, head trauma, myocardial infarction or other insults resulting in interrupted cranial blood flow. The method involves ... | 07/31/2001 |
| 6265150 | Phage antibodies Peripheral blood leucocytes incubated with a semi-synthetic phage antibody library and fluorochrome-labeled CD3 and CD20 antibodies were used to isolate human single chain Fv antibodies specific for subsets of blood leucocytes by flow cytometry. Isolated ... | 07/24/2001 |
| 6265227 | Method for assaying antigen related to disorders caused by mental stress The invention relates to the development of a method for assaying an antigen which is associated with disorders caused by mental stress in a human body fluid by way of an immunoassay technique which utilizes an antibody against a mental stress related pro... | 07/24/2001 |
| 6262265 | Non-hydrolyzable analogs of heroin metabolites suitable for use in immunoassay Novel chemical analogs are disclosed for the essential heroin metabolite 6-O-acetyl morphine (6MAM). The analogs optionally can be made to contain protein reactive groups, and can be used to form protein conjugates, fluorescently labeled compounds, and so... | 07/17/2001 |
| 6254830 | Magnetic focusing immunosensor for the detection of pathogens A magnetic focusing immunosensor for the detection of pathogens comprising a laser, an exciting fiber and a collecting fiber, a fiber optic magnetic probe in communication with the collecting and exciting fibers and means for detecting, collecting and mea... | 07/03/2001 |
| 6251687 | Fluorescence energy transfer and intramolecular energy transfer in particles using novel compounds The invention describes the particles comprising an energy donor as a first component and a fluorescent dye as a second component positioned in said particles at an energy exchanging distance from one another, wherein the two components have a Stokes shif... | 06/26/2001 |
| 6248531 | Trans-platinum compound, and diagnostic kit ##STR1## The present invention is concerned with a trans-platinum based compound for use in a method for labelling a bio-organic molecule, having formula (I), wherein A represents a reactive moiety for attachment to a label, D represents a reactive mo... | 06/19/2001 |
| 6248544 | Method of measuring bone resorption rate Tartrate-resistant acid phosphatase (TRAP) has been used as a marker for bone resorption. However, there are two forms of said enzyme in the body: TRAP 5a and TRAP 5b, of which TRAP 5b is a much more specific marker. The present invention is directed to a... | 06/19/2001 |
| 6238931 | Fluorescence energy transfer in particles Particles and methods for the detection or visualization of analytes using fluorescence energy transfer. Particles comprising an energy donor as a first component and a fluorescent dye as a second component positioned in said particles at an energy exchan... | 05/29/2001 |
| 6235538 | Test for detecting substances which alter the conformational structure of zinc fingers The present invention is a method and kit for analyzing a sample, preferably a liquid environmental sample, which may comprise a toxic xenobiotic element or compound, i.e., an environmental pollutant. The method and kit preferably utilize a portion of a m... | 05/22/2001 |
| 6235535 | Fluorescent energy transfer ligand interaction assay on a lipid film This invention relates to a fluorescence-based immunoassay method for the detection of an analyte, or for the measurement of its concentration in a biological sample. The method is based on the ability of a multivalent analyte to induce aggregation of rec... | 05/22/2001 |
| 6232130 | Method for detecting or quantifying carbohydrate containing compounds A method of evaluating a carbohydrate in a sample. The method includes providing a low valency carbohydrate binding ligand, providing a glycoconjugate which includes a label, and a carbohydrate moiety, contacting the low valency carbohydrate binding ligan... | 05/15/2001 |
| 6225132 | Enhanced chromatography using multiphoton detection A method for detecting an analyte of interest present in a mixture at an ultralow concentration includes selecting a radioactive derivatizing agent comprising a multiphoton-emitting radioisotope moiety and a moiety reactive with the analyte of interest, t... | 05/01/2001 |
| 6225046 | Method for detecting microorganisms Methods for detecting microorganisms in a sample by binding detectable particles and fluorescent labelled ligands reactive to the microorganisms. The present invention also includes the use of multiple fluorochromes for the detection of microorganisms and... | 05/01/2001 |
| 6221602 | Functionalized nanocrystals and their use in labeling for strand synthesis or sequence determination Provided are compositions comprising functionalized nanocrystal-labeled nucleobases that are produced by operably linking a nucleobase to a functionalized nanocrystal via reactive functionalities. Also provided are kits comprising a plurality of species o... | 04/24/2001 |
| 6221604 | Electron-deficient nitrogen heterocycle-substituted fluorescein dyes The invention provides compositions electron-deficient nitrogen heterocycle-substituted fluorescein dyes and methods in which the dyes are conjugated to substrates and used as detection labels in molecular biology experiments. The electron-deficient nitro... | 04/24/2001 |
| 6221612 | Photon reducing agents for use in fluorescence assays The present invention provides a method for reducing undesirable light emission from a sample using at least one photon producing agent and at least one photon reducing agent (e.g. dye-based photon reducing agents). The present invention further provides ... | 04/24/2001 |
| 6214628 | Method of conducting an assay of a sample containing an analyte of interest In accordance with the present invention, a method of conducting an assay of a sample containing an analyte of interest includes the step of forming a mixture so as to bring a metal-ligand complex into interactive proximity with the sample containing the ... | 04/10/2001 |
| 6214563 | Photon reducing agents for reducing undesired light emission in assays The present invention provides a method for reducing undesirable light emission from a sample using at least one photon producing agent and at least one photon reducing agent (e.g. dye-based photon reducing agents). The present invention further provides ... | 04/10/2001 |
| 6207464 | Rigidized monomethine cyanines Boron complexes of certain bis-heterocyclic compounds are provided. The complexes resemble monomethine cyanines and are useful for imparting fluorescent properties to materials by covalent and noncovalent association. The compounds have the following gene... | 03/27/2001 |
| 6207392 | Semiconductor nanocrystal probes for biological applications and process for making and using such probes A semiconductor nanocrystal compound is described which is capable of linking to one or more affinity molecules. The compound comprises (1) one or more semiconductor nanocrystals capable of, in response to exposure to a first energy, providing a second en... | 03/27/2001 |
| 6204002 | Gangliosides having fluorescent-tagged ceramide moieties The invention provides a compound represented by the following formula (I) ##STR1## wherein m is an integer of 2-15; n is an integer of 0-12; R represents a sugar chain or a derivative thereof; R' represents a general formula (II) ##STR2## (wherein p is a... | 03/20/2001 |
| 6203994 | Fluorescence-based high throughput sereening assays for protein kinases and phosphatases The invention relates to novel fluorescence-based assays for protein kinases and phosphatases which can be used in high throughput screening. The methods of the invention utilize a competitive immunoassay to determine the amount of substrate that is phosp... | 03/20/2001 |
| 6203974 | Chemiluminescent immunoassay for detection of antibodies to various viruses The subject invention relates generally to immunoassays for detection of antibodies by use chemiluminescent compounds. More particularly, the subject invention relates to chemiluminescent immunoassays to detect antibodies wherein a precomplex mixture is c... | 03/20/2001 |
| 6200762 | Photon reducing agents and compositions for fluorescence assays The present invention provides a method for reducing undesirable light emission from a sample using at least one photon producing agent and at least one photon reducing agent (e.g. dye-based photon reducing agents). The present invention further provides ... | 03/13/2001 |
| 6190923 | Diethylenetriamine-N,N',N"-triacetic acid derivatives The present invention relates to the field of immunoassays for metal ions. The invention presents: chelators, chelates, antibodies specific for the chelates, tracers comprising chelates conjugated to detectable labels, and immunoassays utilizing the foreg... | 02/20/2001 |
| 6190873 | Cyclosporin assay and kit A method of measuring the amount of cyclosporin in a sample suspected of containing cyclosporin is disclosed. A method of inactivating interfering cross-reactive material in an assay for measuring the amount of cyclosporin in a sample suspected of contain... | 02/20/2001 |
| 6184379 | Rhodamine derivatives and the use thereof The invention concerns rhodamine derivatives of the general formulae ##STR1## in which Ca-Cd each denote a C atom, and Ca and Cb as well as Cc and Cd are either linked together by a single bond or by a double bond; X1 to X16 denote independently of one an... | 02/06/2001 |
| 6180340 | Extended dynamic range assays A method and compositions for the detection and/or quantification of an analyte through the use of a plurality of labeled probes, with two or more said probes targeted to different regions of said analyte. In specific embodiments, the labels are separatel... | 01/30/2001 |
| 6171807 | Detection and quantitation of endotoxin by fluorescence polarization Fluorescently labeled ENP as well as methods of preparation are disclosed. Also disclosed is a method of detecting endotoxin in a liquid sample suspected of containing endotoxin, comprising admixing said liquid sample with fluorescently labeled ENP for a ... | 01/09/2001 |
| 6165800 | Chemiluminescent energy transfer conjugates and their uses as labels in binding assays A new class of chemiluminescent acridinium or benzacridinium compounds is disclosed by virtue of forming an intramolecular energy transfer conjugate (ETC) between the acridinium or benzacridinium compound and a luminophore. A method of extending the emiss... | 12/26/2000 |
| 6165729 | Electrochemiluminescent reaction utilizing amine-derived reductant Electrochemiluminescent assay methods for determining an analyte of interest, which methods include forming one or more compositions which include, in the aggregate, (a) a sample to be tested for the analyte of interest, (b) a component capable of specifi... | 12/26/2000 |
| 6159749 | Highly sensitive bead-based multi-analyte assay system using optical tweezers An apparatus and method for chemical and biological analysis, the apparatus having an optical trapping means to manipulate the reaction substrate, and a measurement means. The optical trapping means is essentially a laser source capable of emitting a beam... | 12/12/2000 |
| 6159748 | Evaluation of autoimmune diseases using a multiple parameter latex bead suspension and flow cytometry Immunoassay methods and apparatus are provided which utilize flow cytometry, coated latex microspheres, and labelled antibodies, to simultaneously detect the presence and amount of several antigens or antibodies in a sample. Microspheres can be sized by f... | 12/12/2000 |
| 6143507 | High throughput compatible assay for receptor-TRAF interactions Disclosed is a high throughput compatible assay that is useful for the identification of specific antagonists of TRAF-receptor interactions. The modular flexibility of the assay makes it possible to introduce simple modifications in order to measure the i... | 11/07/2000 |
| 6136612 | Sulfo benz[E]indocyanine flourescent dyes The present invention is directed to fluorescent dyes and its valence tautomers of the formula wherein Q represents a conjugated moiety that increases the fluorescent quantum yield of the compound; R1 is a functionalized group of the formula--(... | 10/24/2000 |
| 6130313 | Rapidly degrading GFP-fusion proteins Green fluorescent protein (GFP) is widely used as a reporter in determining gene expression and protein localization. The present invention provides fusion proteins with a half life of ten hours or less. Such proteins may be constructed by fusing C-termin... | 10/10/2000 |
| 6130101 | Sulfonated xanthene derivatives The present invention describes xanthene dyes, including rhodamines, rhodols and fluoresceins that are substituted one or more times by a sulfonic acid or a salt of a sulfonic acid. The dyes of the invention, including chemically reactive dyes and dye-con... | 10/10/2000 |
