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Class 436/534 - Carrier is water suspendible particles


Subclass of Class 436 - Chemistry: analytical and immunological testing
Definition: Subject matter in which the carrier consists of colloidal
No. of patents: 692
Last issue date: 10/28/2008


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NumberTitleIssue Date
7442553Method for determining the amount of the maleimidyl groups of a particle
A method for quantitatively determining the amount of maleimidyl groups on a polymer fine particle containing at least maleimidyl groups, by allowing a fluorescent material having an SH group to react with the maleimidyl groups and determining the amount of maleimid...
10/28/2008
7390677Immunoassay and immunoassay apparatus
An immunoassay comprises the steps of: (a) mixing a whole blood sample with sensitized insoluble carrier particles smaller than erythrocytes to cause an immune agglutination reaction; (b) introducing the resulting immune agglutination reaction mixture including aggl...
06/24/2008
7371829Haptens, immunogens, antibodies and conjugates to ketamine and its metabolites
The invention provides haptens, immunogens comprising such haptens coupled to an antigenicity-conferring carrier material, conjugates comprising such haptens bonded to a labelling agent as well as, antibodies raised against such immunogens and capable of binding wit...
05/13/2008
7364906Products and methods for single parameter and multiparameter phenotyping of cells
A method of single parameter and multiparameter characterizing of cells, particularly immunophenotyping of cells, is provided. The method preferably uses antibody-coated microspheres which are adapted to bind to specific types of cells. One or more sets of coated mi...
04/29/2008
7354733Method for sorting and separating living cells
We disclose methods of sorting or separating mixtures of living cells (e.g., eukaryotic, prokaryotic, mammalian, pathogenic, bacterial, viral, etc.). We perform our methods by activating cell-selective photophoric labels, which photosensitize and chemically reduce a...
04/08/2008
7351589Products and methods for single parameter and multiparameter phenotyping of cells
A method of single parameter and multiparameter characterizing of cells, particularly immunophenotyping of cells, is provided. The method preferably uses antibody coated microspheres which are adapted to bind to specific types of cells. One or more sets of coated mi...
04/01/2008
7338813Carrier particle latex for assay reagent and assay reagent
An objective of the invention is to provide a carrier particle latex for an assay reagent capable of assaying a biological sample at a wide range of the concentration in an immunoserological test and capable of being stored stably for a prolonged period, as well as ...
03/04/2008
7332349Detection of cell membrane-associated proteins using membrane fragments displayed on encoded microparticle arrays
Disclosed are methods relating to cell membrane fragments associated with microbeads, so that the characteristics of the cells the fragments originated from can be determined. The fragments can be oriented with what was the outer surface of the cell membrane facing ...
02/19/2008
7316905Method for measurement of hepatitis C virus
A method for measurement of the hepatitis C virus (HCV) characterized by measuring HCV core antigen and HCV core antibody by their binding with probes in the presence of an anionic surfactant or a non-ionic surfactant, or both. ...
01/08/2008
7315378Optical arrangement for assay reading device
Disclosed, in one aspect, is an assay result reading device for reading the result of an assay performed using a test strip, the device comprising: a light source or sources, said light source/s emitting light incident upon at least two, spatially separated zones of...
01/01/2008
7309723Redox polymer nanoparticles
The invention provides nanoparticles comprising one or more redox-active species, methods of making such nanoparticles, and methods for using such nanoparticles, for example, as diagnostic agents for the detection of various analytes. ...
12/18/2007
7297554Immunoassay system
A competitive immunoassay, dye and method for rapidly detecting the presence of one or more target ligands within a fluid sample suspected of containing such ligand or ligands. The immunoassay comprises a protein-binding membrane, a first absorbent pad, a second abs...
11/20/2007
7270970Point of care diagnostic systems
Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and operating rooms, or in any situation in which a rapid and accurate res...
09/18/2007
7262063Directed assembly of functional heterostructures
The present invention relates to a systematic process for the creation of functionally organized, spatially patterned assemblies polymer-microparticle composites including the AC electric field-mediated assembly of patterned, self supporting organic (polymeric) film...
08/28/2007
7253006Device and method for manufacturing bead array, and method for detecting target substance
A device for manufacturing a bead array is provided including a container, a liquid including a bead having a biological substance fixed on a surface of the bead, and means for ejecting the liquid including the bead on a desired position on a solid-phase base. A met...
08/07/2007
7244622Device and method for multiple analyte detection
The invention is directed to a method and device for simultaneously testing a sample for the presence, absence, and/or amounts of one or more of a plurality of selected analytes. The invention includes, in one aspect, a device for detecting or quantitating a plurali...
07/17/2007
7229835Amine detection method and materials
A compound linked to a solid support (R) through a divalent linker moiety (X) and which is represented by the following formula: is disclosed. In particular, the 1-hydroxybenzotriazole-6-carboxylic acid is direct...
06/12/2007
7227688Apparatus for applying optical gradient forces
An apparatus and method for manipulating small dielectric particles. The apparatus and method involves use of a diffractive optical element which receives a laser beam and forms a plurality of light beams. These light beams are operated on by a telescope lens system...
06/05/2007
7217531Multiplex analysis using membrane-bound sensitizers
The present invention is directed to methods and compositions for determining the presence, absence, and/or amounts of one or more membrane-associated analytes in a sample. In accordance with the invention, binding compounds derivatized with releasable molecular tag...
05/15/2007
7202092Indinavir derivatives useful in immunoassay
Derivatives and conjugates of indinavir for generation of antibodies and labeled conjugates for use for detection of indinavir in biological samples. The derivatives are synthesized out of the indane ring hydroxyl group or the pyridine ring nitrogen of indinavir. Al...
04/10/2007
7202348Monoclonal antibody antagonists for treating medical problems associated with d-amphetamine-like drugs
The present invention provides synthetic immunochemical haptens for the generation of antibodies that are designed to recognize the common molecular features of d-methamphetamine-like abused stimulants with insignificant cross-reactivity to endogenous substrates (e....
04/10/2007
7198702Method for separating substances using dielectrophoretic forces
The present invention has an object of providing a method by which two kinds or more of molecules can be separated each other by using dielectrophoretic forces. The present invention comprises two methods. The first method is a method comprising forming a complex su...
04/03/2007
7192724Method for differentiating irritable bowel syndrome from inflammatory bowel disease (IBD) and for monitoring persons with IBD using total endogenous lactoferrin as a marker
A method for aiding in differentiating irritable bowel syndrome from inflammatory bowel disease by determining the level of total endogenous human lactoferrin in clinical specimens, such as feces, mucus and bile, wherein an elevated level of lactoferrin substantiall...
03/20/2007
7192786Biospecific assay method
This invention relates to a biospecific assay method, in which microparticles coated with the bioaffinity reactant A binding the analyte to be assayed; the sample to be analyzed, and the labelled bioaffinity reactant B are mixed. After the binding reaction the signa...
03/20/2007
7179660Carriers coated with polysaccharides, their preparation and use
A polysaccharide coated carrier having a coating of at least two successive layers of polysaccharide. The first polysaccharide layer spontaneously associates with a second polysaccharide layer and, optionally, the carrier. Each successive layer of polysaccharide spo...
02/20/2007
7176036Electroactive microspheres and methods
Methods and devices for electrochemical detection of a specific binding pair member utilizing a microsphere with an incorporated electroactive marker, wherein a member of the specific binding pair to be detected is bound, directly or through one or more intermediate...
02/13/2007
7176174Water-in-oil emulsion
A water-in-oil emulsion composition is disclosed. The composition contains (A) a solvent, (B) water, and (C) a surfactant. This composition is suitable for removing non-aqueous coatings such as paints and the like as well as waxes and greases from substrates. ...
02/13/2007
7166477Muscle sample prepared for prion assay
A method of preparing a sample of muscle tissue and of assaying the prepared sample to determine the presence of prions in the sample is disclosed. The muscle tissue is homogenized and mixed with a complexing agent which forms a complex with a higher specific gravit...
01/23/2007
7148196Anticancer compounds and methods
The testing of tumor cells, including human tumors capable of metastases, in assays employing fibronectin-depleted substrates is described. Ex vivo induction of cells, including biopsied human cells, is performed with invasion-inducing agents. Additionally, anti-can...
12/12/2006
7148024Busulfan immunoassay
Novel conjugates of busulfan and novel busulfan immunogens derived from α-substituted derivatives of busulfan and antibodies generated by these busulfan linked immunogens are useful in immunoassays for the quantification and monitoring of busulfan in biological flu...
12/12/2006
7144742Quantitative lateral flow assays and devices
This invention provides solid phase specific binding lateral flow assay methods, devices and kits for quantitating high and low molecular weight analytes. The methods and devices of the invention employ labelled reagents which are either analyte analogs or complemen...
12/05/2006
7144823Thermal treatment apparatus
The present invention is a thermal processing unit including: a heating-furnace body whose upper end has an opening; a heating unit provided on an inside wall of the heating-furnace body; a reaction container consisting of a single tube contained in the heating-furn...
12/05/2006
7144119System and method for programmable illumination pattern generation
An apparatus providing programmable illumination pattern generation for the manipulation of colloidal particulates and biomolecules in suspension between electrodes, is disclosed. The apparatus implements LEAPS (Light-controlled electrokinetic assembly of particles ...
12/05/2006
7141431Microparticles with multiple fluorescent signals and methods of using same
This invention provides a novel fluorescent particle including a core or carrier particle having on its surface a plurality of smaller polymeric particles or nanoparticles, which are stained with different fluorescent dyes. When excited by a light source they are ca...
11/28/2006
7138280Masking of the background fluorescence and luminescence in the optical analysis of biomedical assays
In a process for the quantitative optical analysis of biological cells labelled with a fluorescent dye, the sensitivity of analytical detection can be considerably improved if a masking dye, which absorbs the excitation light for the fluorescent dye and/or its emiss...
11/21/2006
7115383Assays for amphetamine and methamphetamine
Methods, compositions and kits are disclosed. The compounds disclosed comprise an amphetamine moiety and a methamphetamine moiety linked together by a first linking group. A second linking group depends from the first linking group and comprises a functional group. ...
10/03/2006
7109042Assays
An analytical test device useful for example in pregnancy testing, comprises a hollow casing (500) constructed of moisture-impervious solid material, such as plastics materials, containing a dry porous carrier (510) which communicates indirectly with t...
09/19/2006
7104659Apparatus for using optical tweezers to manipulate materials
A method and apparatus for control of optical trap arrays and formation of particle arrays using light that is in the visible portion of the spectrum. The method and apparatus provides a laser and a time variable diffractive optical element to allow dynamic control ...
09/12/2006
7097983Method for detecting the presence of an analyte in a sample
The invention features a method of determining whether one or more members of an analyte family are present in a sample. The method makes use of a test zone binder, e.g., a receptor that can bind one or a plurality of analytes within an analyte family, the analytes ...
08/29/2006
7083914Color-encoding and in-situ interrogation of matrix-coupled chemical compounds
A method and apparatus for the physico-chemical encoding of a collection of beaded resin (“beads”) to determine the chemical identity of bead-anchored compounds by in-situ interrogation of individual beads. The present invention provides method and apparatus to ...
08/01/2006
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