Did You Know...
...that the Band-Aid Bandage was invented by a Johnson & Johnson employee whose wife had cut herself? Earl Dickson's wife was rather accident prone, so he set out to develop a bandage that she could apply without help. He placed a small piece of gauze in the center of a small piece of surgical tape, and what we know today as the Band Aid bandage was born!
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| Number | Title | Issue Date |
| 7329484 | Retentate chromatography and protein chip arrays with applications in biology and medicine This invention provides methods of retentate chromatography for resolving analytes in a sample. The methods involve adsorbing the analytes to a substrate under a plurality of different selectivity conditions, and detecting the analytes retained on the substrate by d... | 02/12/2008 |
| 7326579 | Immunoassay method for lyzed whole blood The present invention provides an immunoassay method in which blood can be measured even without pretreatment by means of a centrifuge etc. In the present invention, antibodies or antigens in a sample are subjected to agglutination reaction with insoluble carriers o... | 02/05/2008 |
| 7312089 | Detection of erythropoietin and erythropoietin receptor The invention is based on the development of several sensitive and simple methods for detecting erythropoietin and the erythropoietin receptor and associated antibodies. The methods and reagents are useful for differential diagnosis in Epo and EpoR related clinical ... | 12/25/2007 |
| 7309611 | Prewetting stop flow test strip A test strip and method for detecting an analyte present in a sample. The test strip comprising: a buffer addition zone to which a buffer may be added; an absorbent zone proximal to the buffer addition zone; one or more test zones distal to the buffer addition zone,... | 12/18/2007 |
| 7291504 | Assay involving detection and identification with encoded particles A method and apparatus for the manipulation of colloidal particles and biomolecules at the interface between an insulating electrode such as silicon oxide and an electrolyte solution. Light-controlled electrokinetic assembly of particles near surfaces relies on the ... | 11/06/2007 |
| 7291477 | Method and device for detection A method and kit for detecting Trichomonas vaginalis infection in a human subject are disclosed. In the method, a body-fluid sample such as a vaginal swab sample or urine is obtained from the subject and contacted with an antibody specific against a Tricho... | 11/06/2007 |
| 7288415 | Compositions and methods for capturing, isolating, detecting, analyzing and quantifying macromolecules The present invention provides imprint compositions useful for capturing, isolating, detecting and/or quantifying macromolecules in a sample, methods of making and using the same. Generally, the imprint compositions comprise a matrix material defining an imprint of ... | 10/30/2007 |
| 7288416 | Ionic polymers and polymer-comprising substrates An objective of the present invention is to provide ionic polymers that can provide for polymer-comprising substrates whose surfaces can stably and easily immobilize ligands such as sugar chains interacting with biological substances, in which the ligand portion exi... | 10/30/2007 |
| 7279339 | Reagent for an immunoassay The present invention relates to (1) A reagent for an immunoassay of a target substance existing in a free form and a bound form in a specimen, comprising a latex 1 which is immobilized with a monoclonal antibody 1 for the target substance, and a latex 2 which has a... | 10/09/2007 |
| 7279323 | Method for conducting receptor-ligand association reaction and reactor used therefor A method for conducting a receptor-ligand association reaction includes the steps of dipping a biochemical analysis unit including a substrate formed with a plurality of absorptive regions which contain receptors or ligands and are formed to be spaced apart from eac... | 10/09/2007 |
| 7270995 | Analyzing device The present invention is an analytical device which comprises a porous piece assembly consisting of a liquid reagent-receiving porous piece (1), a labeled substance-retaining piece (2), a test piece (3) comprising a detection site (4) and... | 09/18/2007 |
| 7270970 | Point of care diagnostic systems Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and operating rooms, or in any situation in which a rapid and accurate res... | 09/18/2007 |
| 7271008 | Quality control of assays The invention relates to a device and methods for determining the quality of reagents used in an assay process, particularly a multistep immunohistochemical assay. In particular, the device comprises a substrate with a plurality of compounds affixed to a substrate, ... | 09/18/2007 |
| 7267992 | Method for the determination of an analyte in a liquid A method is provided to determine the presence of an analyte in a sample. The method provides an element with a sample application zone, a detection zone, a zone containing immobilized analyte or analyte analogue, a conjugate that has a first bioaffine binding partn... | 09/11/2007 |
| 7267993 | Phage ligand sensor devices and uses thereof Methods and compositions for identifying and characterizing one or more ligands of a peptide are provided. In particular, the invention provides a phage ligand sensor device (PLSD) comprising a sensor coupled to a binding element of interest. Binding elements of int... | 09/11/2007 |
| 7267957 | Detection and amplification of ligands A system for the detection of ligands comprising at least one receptor and an amplification mechanism coupled to the receptor wherein an amplified signal is produced as a result of receptor binding a ligand. Examples of suitable amplification mechanisms include anti... | 09/11/2007 |
| RE39816 | Conjunctive analysis of biological marker expression for predicting cardiac mortality A diagnostic tool is disclosed for accurately and rapidly diagnosing the condition of an ailing organ. Although applicable to numerous organ and organ systems, this application particularly illustrates the concept of conjunctive marker utilization as it relates to d... | 09/04/2007 |
| 7262281 | Method of depositing S-layer proteins on a carrier to immobilize functional molecules On a carrier surface, a layer of S-layer proteins is produced as a carrier of functional molecules. A solution containing S-layer proteins in the form of monomers or oligomers is brought into contact with the carrier surface. Electrochemical conditions are produced ... | 08/28/2007 |
| 7258980 | Determining non-nucleic acid molecule binding to target by competition with nucleic acid ligands A competitive binding assay is used to determine whether a non-nucleic acid molecule from a library of non-nucleic acid molecules binds to a target. The non-nucleic acid molecule competes with a labeled nucleic acid ligand for binding to the target which may be immo... | 08/21/2007 |
| 7252938 | Methods and devices for producing a polymer at a location of a substrate Methods and devices for producing a polymer at a location of a substrate are provided. In the subject methods, a fluid droplet containing a first monomer labeled with a first detectable label is deposited from a fluid deposition device onto a location of a substrate... | 08/07/2007 |
| 7247489 | Ion-detecting microspheres and methods of use thereof This invention provides methods of using ion-detecting microspheres containing an ionphore and a chromoionphore in clinical laboratory instrumentation such as flow cytometry for sample analysis. In one embodiment, the microspheres are contacted with a flowing stream... | 07/24/2007 |
| 7241627 | Wearable article with multi-level alert system A wearable article equipped with a multi-level alert system detects and emits signals corresponding to various abnormal levels of a substance in a mammalian extract. By providing different signals corresponding to multiple abnormal levels of the substance, the weare... | 07/10/2007 |
| 7238537 | Assays An analytical test device incorporating a dry porous carrier to which a liquid sample, eg. urine, suspected of containing an analyte such as HCG or LH can be applied indirectly, the device also incorporating a labelled specific binding reagent which is freely mobile... | 07/03/2007 |
| 7238539 | Magnetizable bead detector A ferromagnetic thin-film based magnetic field detection system used for detecting the presence of selected molecular species. A magnetic field sensor supported on a substrate has a binding molecule layer positioned on a side thereof capable of selectively binding t... | 07/03/2007 |
| 7238536 | Controlled transport through multiple reversible interaction point membranes A membrane comprising two or more macromolecules that interact via multiple reversible physical interaction points (MRIPM). The membrane further comprises a chemical species A, which interacts selectively or nonselectively with the MRIPM; and a chemical species B, w... | 07/03/2007 |
| 7232661 | Diagnostic agents for the prenatal diagnosis of preterm delivery, fetal infection, and fetal damage, and diagnostic kit containing the same This invention is about a method for the prenatal diagnosis of preterm delivery, fetal infection, and fetal damage, and diagnostic reagent system and diagnostic kit for the diagnosis. The method, diagnostic reagent system, and kit are based on the finding that the l... | 06/19/2007 |
| 7229835 | Amine detection method and materials A compound linked to a solid support (R) through a divalent linker moiety (X) and which is represented by the following formula: is disclosed. In particular, the 1-hydroxybenzotriazole-6-carboxylic acid is direct... | 06/12/2007 |
| 7229839 | Bidirectional lateral flow test strip and method A test strip adapted to receive a sample and detect an analyte therein is provided. The test strip comprises a sample addition zone to which a sample may be added; an absorbent zone proximal to the sample addition zone; one or more test zones distal to the sample ad... | 06/12/2007 |
| 7214546 | Dendritic chemiluminescent substrates Chemiluminescent substrate delivery systems comprising a conjugate of a dendrimer and at least one chemiluminescent substrate are provided. The substrate delivery systems can also include a chemiluminescence enhancer. The dendrimer/chemiluminescent substrate conjuga... | 05/08/2007 |
| RE39606 | Methods and apparatus for synthesizing labeled combinatorial chemistry libraries The present invention provides labeled synthetic libraries of random oligomers and methods and apparatus for generating labeled synthetic oligomer libraries. Each member of such a library is labeled with a unique identifier tag that specifies the structure or sequen... | 05/01/2007 |
| 7208286 | Bioluminescent bioreporter integrated circuit devices and methods for detecting ammonia Monolithic bioelectronic devices for the detection of ammonia includes a microorganism that metabolizes ammonia and which harbors a lux gene fused with a heterologous promoter gene stably incorporated into the chromosome of the microorganism and an Optical Applicati... | 04/24/2007 |
| 7208322 | Sensor surfaces for detecting analytes The present invention provides a sensor surface comprising: a substrate coated with a free electron metal; and a matrix layer disposed on the free electron metal, wherein the matrix layer comprises an organic compound having a boronic acid complexing moiety. The mat... | 04/24/2007 |
| 7205157 | Method of separating cells from a sample Rare cells are separated from a sample fluid by a positive selection or negative selection antibody by centrifuging in a tube containing a harvesting float. The harvesting float has an axial passage and a density to settle in the sample fluid and expand the layer of... | 04/17/2007 |
| RE39571 | Methods and apparatus for synthesizing labeled combinatorial chemistry libraries The present invention provides labeled synthetic libraries of random oligomers and methods and apparatus for generating labeled synthetic oligomer libraries. Each member of such a library is labeled with a unique identifier tag that specifies the structure or sequen... | 04/17/2007 |
| 7202076 | Label-free high-throughput optical technique for detecting biomolecular interactions Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters. ... | 04/10/2007 |
| RE39545 | Methods and apparatus for synthesizing labeled combinatorial chemistry libraries The present invention provides labeled synthetic libraries of random oligomers and methods and apparatus for generating labeled synthetic oligomer libraries. Each member of such a library is labeled with a unique identifier tag that specifies the structure or sequen... | 04/03/2007 |
| 7198954 | Methods for predicting pregnancy outcome in a subject by hCG assay The present invention provides a method of predicting pregnancy outcome in a subject by determining the amount of an early pregnancy associated molecular isoform of hCG in a sample. The present invention further provides a method for determining the amount of early ... | 04/03/2007 |
| 7195924 | Method for immobilizing a biomolecule on a solid substrate at a high density by using the substrate having an activated carboxyl group on a surface thereof and microarray produced using the method Provided is a method for immobilizing a biomolecule on a solid substrate. The method includes coating the solid substrate with silane anhydride to introduce an anhydride functional group onto a surface of the solid substrate; obtaining a carboxyl group from the anhy... | 03/27/2007 |
| 7179659 | Sensor surfaces for detecting analytes and methods of use The present invention provides a method for detecting an analyte, comprising providing a sensor comprising a substrate coated with a free electron metal, a matrix layer disposed on the free electron metal, the matrix layer comprising an organic compound, wherein the... | 02/20/2007 |
| 7179657 | Method for adding an apparent non-signal line to a rapid diagnostic assay A test device and method for determining the presence or absence of one or more analytes in a fluid sample, the test device including a support or member bearing a mark thereon, and a matrix or member containing a capture zone. In operation, an observation area in t... | 02/20/2007 |
