Bizarre Patents
Mouthguard made at least partially from an edible candy
A mouthguard includes a U-shaped upper bite plate which removably fits over upper teeth of a person, with the entire upper bite plate being made from a soft, deformable and edible gummi candy.
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| Number | Title | Issue Date |
| 6180135 | Three-dimensional colorimetric assay assemblies A direct assay is described using novel three-dimensional polymeric assemblies which change from a blue to red color when exposed to an analyte, in one case a flue virus. The assemblies are typically in the form of liposomes which can be maintained in a s... | 01/30/2001 |
| 6174686 | Methods for the assay of troponin I and T and complexes of troponin I and T and selection of antibodies for use in immunoassays Assay systems and specialized antibodies for the detection and quantitation of troponin I and troponin T in body fluids as an indicator of myocardial infarction. Since troponin I and T exist in various conformations in the blood, the ratios of the monomer... | 01/16/2001 |
| 6174683 | Method of making biochips and the biochips resulting therefrom Methods for preparing a biochip are provided herein wherein the biomolecular probe to be used with the biochip is alternatively bound to a hydrogel prepolymer prior to or simultaneously with polymerization of the prepolymer. In particularly preferred embo... | 01/16/2001 |
| 6166187 | Method of concentrating prion proteins in blood samples A sample is prepared from blood in a manner which makes it possible to further analyze proteins in the sample, e.g. to detect prions in the sample. Blood is extracted, allowed to clot and subjected to separation processing (e.g. centrifugation) to obtain ... | 12/26/2000 |
| 6159749 | Highly sensitive bead-based multi-analyte assay system using optical tweezers An apparatus and method for chemical and biological analysis, the apparatus having an optical trapping means to manipulate the reaction substrate, and a measurement means. The optical trapping means is essentially a laser source capable of emitting a beam... | 12/12/2000 |
| 6159748 | Evaluation of autoimmune diseases using a multiple parameter latex bead suspension and flow cytometry Immunoassay methods and apparatus are provided which utilize flow cytometry, coated latex microspheres, and labelled antibodies, to simultaneously detect the presence and amount of several antigens or antibodies in a sample. Microspheres can be sized by f... | 12/12/2000 |
| 6159742 | Nanometer-scale microscopy probes A carbon-based tip for scanning probe microscopy. The tip used in microscopy to reveal chemical characteristics of a sample includes a structure of the formula: X--(L--M)n in which n is 1 to 100, X is a carbon-based nanotube, L is a linking group ... | 12/12/2000 |
| 6156521 | Methods for the recovery and measurement of troponin complexes The invention relates in part to methods and compositions for identifying the presence, measuring the amount, stabilizing, and facilitating recovery of troponin complexes or individual troponin isoforms in a sample.... | 12/05/2000 |
| 6153394 | Immunoassay for equine protozoal myeloencephalitis in horses An immunoassay for Sarcocystis neurona antibodies in equines is described. The immunoassay uses blocking of Sarcocystis antigens by antibodies to Sarcocystis sp. other than Sarcocystis neurona in connection with the immunoassay.... | 11/28/2000 |
| 6150147 | Biological array fabrication methods with reduction of static charge The present invention provides modified methods and apparatus for the preparation of arrays of material wherein each array includes a preselected collection of polymers, small molecules or inorganic materials associated with a surface of a substrate. The ... | 11/21/2000 |
| 6143577 | Process and installations for separation of magnetic particles in a fluid for biological analysis, and application of said process A process for magnetic immunoseparation of cells, in particular bacteria, fetal cells, stock cells of bone marrow and circulating cancerous cells, of the type consisting in affixing the target cells on paramagnetic balls and in causing a magnetic field to... | 11/07/2000 |
| 6143511 | Sandwich immunoassays for collagen type II degradation products Sandwich immunoassays for detecting analyte indicative of type II collagen resorption in vivo, by contacting a body fluid sample with a first antibody and a second antibody such that analyte present in the sample forms a first antibody-analyte-second anti... | 11/07/2000 |
| 6140045 | Multi-array, multi-specific electrochemiluminescence testing Materials and methods are provided for producing patterned multi-array, multi-specific surfaces which are electronically excited for use in electrochemiluminescence based tests. Materials and methods are provided for the chemical and/or physical control o... | 10/31/2000 |
| 6136551 | Assay for detecting the presence of botulinum toxin neutralizing antibodies in a patient serum sample An assay for the identification of neutralizing botulinum antibodies in sera is provided which includes the steps of separating non-sodium dodecyl sulfate, non-trypsinized complex botulinum toxin in an arylamide gel by electrophoresis, the separation occu... | 10/24/2000 |
| 6127448 | Biocompatible polymeric coating material The invention provides a biocompatible polymeric coating material, wherein the polymeric material is selected from the group consisting of linear, dendrimeric and branched polymers which contain primary, secondary, tertiary or quaternary amine groups with... | 10/03/2000 |
| 6127190 | Method for producing combinatorial libraries having a predetermined frequency of each species of test compound A technique is disclosed for generating nonrandom combinatorial libraries on solid phase supports in which each of a set of predetermined species of test compounds is present on a predetermined number of solid phase supports, preferably on only one, and e... | 10/03/2000 |
| 6127130 | Multiassay method for determining the concentrations of antigens and interferants A method of determining the concentration of a sample antigen in the presence of an interferant by (1) running two immunoassays on the sample: one assay where the interferant influences the binding of both the sample antigen and a labeled antigen and a se... | 10/03/2000 |
| 6124103 | Arrangement and method of examining hydrophilic macromolecules in an aqueous solution An arrangement for the investigation of hydrophilic macromolecules (1) in an aqueous solution having a solid carrier surface (5) onto which a lipid film (24) is disposed, wherein the molecules (1) to be investigated are bound, by means of a molecular coup... | 09/26/2000 |
| 6120856 | Coated, resuspendable magnetically responsive, transition metal oxide particles and method for the preparation thereof The invention relates to an improved method for the manufacture of magnetically responsive particles, also called ferrofluids. The improved method involves a heat treatment step, which may occur at various times during the preparation of the materials, in... | 09/19/2000 |
| 6114179 | Method and test kit for detecting antigens and/or antibodies A suspension of inert particles is prepared in an aqueous solution, to which an antibody or an antigen and a carrier-bound antigen or antibody, respectively, are added in any desired order. After centrifuging, the positive, weakly positive, or negative re... | 09/05/2000 |
| 6107080 | Biosensor device and method A biosensor apparatus for detecting a binding event between a ligand and receptor. The apparatus includes an electrode substrate coated with a high-dielectric hydrocarbon-chain monolayer, and having ligands attached to the exposed monolayer surface. Bindi... | 08/22/2000 |
| 6107066 | Detection of transmembrane potentials by optical methods Methods and compositions are provided for determining the potential of a membrane. In one aspect, the method comprises: (a) introducing a first reagent comprising a hydrophobic fluorescent ion capable of redistributing from a first face of the membrane to a se... | 08/22/2000 |
| 6107050 | Diagnostic test for alzheimers disease The present invention provides methods for the diagnosis of Alzheimer's disease using human cells. Specifically, one method detects differences between potassium channels in cells from Alzheimer's patient and normal donors, and differences in intracellula... | 08/22/2000 |
| 6107045 | Antibodies to lipoproteins and apolipoproteins and methods of use thereof Compositions and methods using antibodies which are immunoreactive with specific apolipoproteins to determine the concentrations of lipoproteins such as HDL and LDL, and/or apolipoproteins in human blood, serum or plasma sample, are described. Monoclonal ... | 08/22/2000 |
| 6103478 | CDT assay The invention provides a method of assessment of carbohydrate-deficient transferrin in a transferrin containing body fluid, said method comprising the steps of: i) obtaining a transferrin containing liquid sample of or derived from a said fluid; ii) conta... | 08/15/2000 |
| 6103217 | Polymeric assemblies for sensitive colorimetric assays The presently claimed invention relates to polymeric assemblies which visibly change color in the presence of analyte. In particular, the presently claimed invention relates to liposomes comprising a plurality of lipid monomers, which comprises a polymeri... | 08/15/2000 |
| 6103484 | Method for immunodiagnosis of heartworm in mammals In accordance with the present invention, a 31-33 kDa glycoprotein of D. immitis (DiT33) is provided which represents another member of the family of putative pepsin inhibitors. Other known members include Ov33 (a.k.a. Ov33.3, Oc3.6, OvD 5B), Bm33 and Av3... | 08/15/2000 |
| 6096825 | Electrically conductive electroactive functionalized conjugated polymers, and uses thereof There are electrically conductive, electroactive functionalized conjugated polymers having formula (I): ##STR1## These electrically conducive, electroactive conjugated polymers may be covalently bonded to a first biological molecule or antiligand. Po... | 08/01/2000 |
| 6096508 | Method of reducing background in biotin-based assays This invention relates to an improvement in a method for detecting labeled molecules and especially biotinylated molecules and particularly relates to a method for reducing background signal problems in such detection methods.... | 08/01/2000 |
| 6093546 | Process for preparing test elements The invention relates to a process for making a test element, such as an analytical test element. Compositions of matter, such as analyte specific receptors, are treated to carry a charge. These are then applied to test carriers treated to carry a charge ... | 07/25/2000 |
| 6090925 | Macromolecular microparticles and methods of production and use Microparticles formed by mixing a macromolecule with a polymer at a pH near the isoelectric point of the macromolecule and incubating the mixture in the presence of an energy source for a predetermined length of time. The microparticles are composed of ho... | 07/18/2000 |
| 6090912 | Topologically segregated, encoded solid phase libraries comprising linkers having an enzymatically susceptible bond The invention relates to libraries of synthetic test compound attached to separate phase synthesis supports. In particular, the invention relates to libraries of synthetic test compound attached to separate phase synthesis supports that also contain codin... | 07/18/2000 |
| 6087186 | Methods and apparatus for synthesizing labeled combinatorial chemistry libraries The present invention provides labeled synthetic libraries of random oligomers and methods and apparatus for generating labeled synthetic oligomer libraries. Each member of such a library is labeled with a unique identifier tag that specifies the structur... | 07/11/2000 |
| 6087185 | Integrated packaging holder device for immunochromatographic assays in flow-through or dipstick formats The prevent invention relates to an integrated package-holder assay devices for detecting the presence of analyte in a sample. The device serves the dual roles of supporting and protecting an immunochromatographic assay. The device is compatible with any ... | 07/11/2000 |
| 6087184 | Opposable-element chromatographic assay device for detection of analytes An assay device for detection or determination of an analyte in a sample uses opposable components and is suitable for assay of human chorionic gonadotropin and other protein or glycoprotein hormones. One embodiment of the device comprises: (1) a first op... | 07/11/2000 |
| 6086821 | Ultrasonic force differentiation assay An ultrasonic energy source is used to provide a variable force for measuring the binding forces between molecular entities and for sensing the presence of an analyte in a test sample. The device includes a surface that has a first binding member attached... | 07/11/2000 |
| 6078782 | Methods for improved particle electrochemiluminescence assays The invention relates to methods of performing a binding assay for an analyte of interest present in a sample based upon electrochemiluminescence at an electrode of interest. Particles are employed in the method, which are then collected in a zone at whic... | 06/20/2000 |
| 6077681 | Diagnosis of motor neuropathy by detection of antibodies Methods of detecting antibody to GM1 ganglioside in a sample, comprising covalent linkage of GM1 ganglioside to a solid-phase reactant, are disclosed. The methods of detecting antibody to GM1 ganglioside can be used in methods of diagnosing motor neuropat... | 06/20/2000 |
| 6068986 | Antibodies specific for d-myo-inositol 1,4,5-trisphosphate and the enzyme-linked immunosorbent assay of d-myo-inositol 1,4,5-trisphosphate Antibodies against Ins(1,4,5)P3 were raised by immunizing rabbits with two types of IP3 -BSA conjugates which were synthesized by covalently coupling Ins(1,4,5)P3 to the carrier protein via alkyl linkages. The anti-Ins(1,4... | 05/30/2000 |
| 6066331 | Method for preparation of vesicles loaded with biological structures, biopolymers and/or oligomers A composition useful for preparing vesicles loaded with biological cell-structures, biopolymers and/or -oligomers is prepared by solubilizing amphiphatic material such as a phospholipid in a polar-protic solvent miscible with water, solubilizing biologica... | 05/23/2000 |
