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| Number | Title | Issue Date |
| 4594327 | Assay method for whole blood samples Methods and compositions are provided for performing an assay on whole blood samples. The method is for a determination of an analyte which is a member of a specific binding pair (sbp) consisting of ligand and homologous receptor. The method involves a bi... | 06/10/1986 |
| 4594326 | Time-integrated measurement for determining substances in biological fluids A method for obtaining a measurement of the time integral of concentrations of substances in a biological fluid, without the necessity to collect samples of that fluid, and a device useful in the practice of that method. The concepts accomplish time-integ... | 06/10/1986 |
| 4563418 | Process for detection of selected motile organisms A motility-immunoimmobilization method permits the detection of a particular motile organism, such as Salmonella, in a sample.... | 01/07/1986 |
| 4562147 | Method and kit for diagnosis of pseudorabies A radial immunodiffusion enzyme assay method for the simple testing of pseudorabies antibodies in swine and other animals. Agar test plates are provided including an underlying adherent coating of solubilized non-infectious swine pseudorabies antigen. Blo... | 12/31/1985 |
| 4557955 | Shaped articles which are composed of a copolymer containing fluorine groups and which are selectively permeable to liquids and gases and are simultaneously oleophobic and oleophilic The invention relates to films and tubular structures which are selectively permeable to liquids and gases which are based on a copolymer composed of a copolymerized fluorinated olefin, copolymerized vinyl acetate and, optionally, a copolymerized olefin. ... | 12/10/1985 |
| 4517288 | Solid phase system for ligand assay A method for conducting a ligand assay in an inert porous medium wherein a binding material is immunologically immobilized within the medium, which includes the steps of immunologically immobilizing a binding material within a finite zone of the medium, a... | 05/14/1985 |
| 4515889 | Method for carrying out analytical determinations The present invention provides a process for carrying out analytical determinations by mixing and incubating a sample solution with at least one reagent and optically measuring a parameter in the incubated reaction mixture. The mixing, incubating and meas... | 05/07/1985 |
| 4446232 | Enzyme immunoassay with two-zoned device having bound antigens A device for determining the presence of antigens which comprises a first zone containing antigens and enzyme-linked antibodies which are capable of immunologically reacting with said antigens, said antibodies being positioned in said first zone such that... | 05/01/1984 |
| 4436824 | Leukocyte migration through antigen containing agaroses for immunocompetence testing The method assesses the level of general and specific cellular immunocompetence by measuring the responses of individuals to antigens in vitro employing the phenomenon of Leukocyte Migration Inhibition (LMI). The present invention differs from the previou... | 03/13/1984 |
| 4435504 | Immunochromatographic assay with support having bound "MIP" and second enzyme Chromatographic immunoassay employing a specific binding pair member and a label conjugate which delineates a border whose distance from one end of the chromatograph relates to the amount of analyte present. By combining the label conjugate and sample in ... | 03/06/1984 |
| 4403041 | Diagnosis of atherosclerosis A novel method of diagnosis of atherosclerosis comprises comparing the migration of endothelial cells or of cells of endothelium-like morphology in vitro, in the presence of serum from the person being examined, with the migration of identical cells in th... | 09/06/1983 |
| 4399099 | Optical fiber apparatus for quantitative analysis This invention relates to a method and to apparatus for chemical and biochemical analyses which employ an energy-transmissive core and may employ one or more sheaths which selectively absorb, react with, and/or filter an analyte or a product of an analyte... | 08/16/1983 |
| 4398894 | Method for quantitatively determining the degree of agglutination of particles A method and apparatus for quantitatively determining a degree of agglutination of a suspension of particles or the presence of the agglutination thereof is disclosed, wherein a liquid which contains agglutinated clots, otherwise a substance or substances... | 08/16/1983 |
| 4323439 | Method and apparatus for dynamic equilibrium electrophoresis Novel method and apparatus for separating, purifying and/or concentrating ions in a mixture of different molecular species using a method of electrophoresis in the presence of a counterflowing carrier fluid are provided. By selecting the appropriate carri... | 04/06/1982 |
| 4292154 | Buffer composition and method for the electrophoretic separation of proteins A buffer composition for use in the electrophoretic separation of proteins into fractions, the buffer composition consisting essentially of Tris; an acid having the formula R1 --CO--NH--R2 --COOH where R1 is NH2... | 09/29/1981 |
| 4244803 | Quantitative protein analysis by immunodiffusion Methods and apparatus are described by which immunochemical procedures such as immunodiffusion and immunoelectrophoresis can be used to provide quantitative measurement of the concentration of individual proteins in fluids such as serum, spinal fluid, tis... | 01/13/1981 |
| 4235601 | Test device and method for its use Test device for determining a characteristic of a sample, particularly for determining substances in fluid samples. The device comprises a strip element which is composed of a material capable of transporting a developing fluid therealong by capillarity a... | 11/25/1980 |
| 4222744 | Assay for ligands Assay for a ligand wherein the ligand is contacted in a fluid with (1) labeled binder or (2) binder and labeled reference ligand, and the presence of ligand determined from the movement of labeled material in at least one region of the fluid. In a particu... | 09/16/1980 |
| 4200508 | Method and composition for detecting antigenic substances A method and composition for detecting an antigenic substance by immunodiffusion using an antigenic substance to be detected labeled by a chromogenic enzyme. According to the method and the detection material of this invention, even a small amount of an a... | 04/29/1980 |
| 4181501 | Method and apparatus for measuring antibody levels A diagnostic device is described employing a solid, rigid diagnostic substrate (having as a part thereof an exposed layer of first immunologically reactive biological particles) in combination with means spaced therefrom for containing a solution of secon... | 01/01/1980 |
| 4162208 | Quantitative protein analysis by immunodiffusion Methods are described by which immunochemical procedures such as immunodiffusion and immunoelectrophoresis can be used to provide quantitative measurement of the concentration of individual proteins in fluids such as serum, spinal fluid, tissue extracts a... | 07/24/1979 |
| 4081241 | Diagnostic process An in vitro method for the diagnosis of immunization states which involves measuring, in an electric field, the changed mobility of charged indicator particles, other than macrophages, which particles have been treated with (1) a suspension of lymphocytes... | 03/28/1978 |
| 4080264 | Immunoassay by light scattering spectroscopy This inventin provides a means for determining the concentration of any of a wide range of antibody or antigen molecules with a high degree of specificity, accuracy and sensitivity. Antigen or antibody concentration is determined by effecting an agglutina... | 03/21/1978 |
| 4028056 | Substance separation technique Apparatus and a method of separating a particulate portion as defined herein from a mixture including a liquid portion, including introducing the mixture into a stream of wash solution flowing along an open bore of a conduit, the wash solution having immi... | 06/07/1977 |
| 4011044 | Use of laser speckle patterns for measurement of electrophoretic mobilities Reduction in electrophoretic mobility of antigen-coated microscopic polystyrene spheres due to an antigen-antibody reaction is detected by observing changes in oscillation amplitude of speckle patterns (i.e., regions of light and dark) produced by laser l... | 03/08/1977 |
| 3981776 | Magnetically responsive, biologically active substance and associated methods and apparatus A biologically active substance is incorporated in a unitary body with a magnetically responsive material for carrying out diffusion testing. These may be, microbiological, immunological, serological and other biochemical examinations. The body is applied... | 09/21/1976 |
| 3969497 | Test substance for tuberculosis A new test substance for use in skin testing for tuberculosis, which substance is produced from Mycobacterium tuberculosis (M.tb.) culture filtrate or bacillary extract. The culture filtrate or extract is first fractionated by means of chromatography. Res... | 07/13/1976 |
| 3960488 | Method and apparatus for quantitative surface inhibition test A metallized slide has adsorbed thereon a first monomolecular layer of particular first immunologically reactive biological particles and is covered with a suitable moisture holding medium. A test solution is then applied along a first edge of the slide, ... | 06/01/1976 |
| 3960489 | Method and apparatus for determination of concentration of immunologically reactive biological particles The area of a bimolecular layer formed on a metallized slide is related to the concentration of second immunologically reactive biological particles forming the second layer. The slide initially has adsorbed thereon a first monomolecular layer of first im... | 06/01/1976 |
| 3960491 | Method and apparatus for detecting immunologically reactive biological particles A metallized solid substrate is covered with a moistened porous paper, and specimens of first and second solutions suspected of respectively containing first and second immunologically reactive biological particles specific to each other are applied to se... | 06/01/1976 |
