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| Number | Title | Issue Date |
| 7691644 | Devices for the detection of multiple analytes in a sample The present invention relates generally to an assay for detecting and differentiating multiple analytes, if present, in a single fluid sample, including devices and methods therefore. ... | 04/06/2010 |
| 7670853 | Assay device, system and method A system for treating a blood sample (700) having an analyte of interest comprises a strip (200) having a membrane (218), respective portions (216, 220 and 222, or 300) which are provided for receiving the sample, for lysing... | 03/02/2010 |
| 7670854 | Immunological assay and chip The present invention provides an immunological assay suitable to be carried out on a chip. After an antigen-antibody complex in which an antigen 2 to be measured and an antibody 3 have bound to each other was obtained in a reaction chamber 7, t... | 03/02/2010 |
| 7662643 | Reduction of the hook effect in membrane-based assay devices A membrane-based assay device for detecting the presence or quantity of an analyte residing in a test sample is provided. The device utilizes a chromatographic zone on which is disposed a plurality of microporous particles. The chromatographic zone can effectively r... | 02/16/2010 |
| 7655477 | System and method for the separation of analytes A separation module operates to fractionate or separate an analyte into fractions according to pI, i.e., pI bands, utilizing capillary isoelectric focusing (“CIEF”) within a first microchannel. The fractions are stacked to form plugs, the number of which is dete... | 02/02/2010 |
| 7638344 | Active agent eluting matrices with particulates The present invention is directed to polymeric matrices for the controlled release of a hydrophilic bioactive agent. Generally, the elution control matrix includes a polymeric matrix having a first polymer and a plurality of microparticles that include the hydrophil... | 12/29/2009 |
| 7629178 | Assays An analytical test device incorporating a dry porous carrier to which a liquid sample, eg. urine, suspected of containing an analyte such as HCG or LH can be applied indirectly, the device also incorporating a labelled specific binding reagent which is freely mobile... | 12/08/2009 |
| 7625763 | Rapid diagnostic test systems and methods A rapid diagnostic test system includes a lateral-flow strip for performing a binding assay. The lateral-flow strip contains a binding agent having a deposition density that varies periodically along at least a portion of the lateral-flow strip. The test system furt... | 12/01/2009 |
| 7608466 | Process and device for producing reagent carriers The invention concerns a process for producing reagent carriers having a binding capability that are suitable for determining analytes in liquids, wherein the process comprises at least one step of treating a respective reagent carrier body in particular by transfer... | 10/27/2009 |
| 7601546 | Diagnostic test devices A diagnostic test apparatus comprising: a shaft having a first end and a second end; a swab or a biopsy punch mounted on the first end of a shaft; and a cap for fitting over the first end of the shaft, said cap containing at least one diagnostic test reagent; wherei... | 10/13/2009 |
| 7598090 | Biosensor A biosensor is provided with an area in which a reagent having bleaching action is carried in a state where it can be dissolved, at least in a part of a sample application area to which an inspection target solution is applied or the downstream of the sample applica... | 10/06/2009 |
| 7598091 | Micromachined diagnostic device with controlled flow of fluid and reaction This invention relates to a micromachined microfluidics diagnostic device that comprises one or multiple assaying channels each of which is comprised a sample port, a first valve, a reaction chamber, a second valve, a fluid ejector array, a third valve, a buffer cha... | 10/06/2009 |
| 7575938 | Method for diagnosing liver diseases The present invention relates to a method for diagnosing a liver disease rapidly in an early stage. More particularly, the present invention relates to a monoclonal antibody against asialo α1-acid glycoprotein; a method for diagnosing a liver disease which evaluate... | 08/18/2009 |
| 7569396 | Caffeine detection using internally referenced competitive assays Methods, compositions, and apparatus for detecting the presence of caffeine in a liquid sample are provided. In certain embodiments, an internally referenced competitive assay allows a very precise determination of a threshold value of caffeine for use in semiquanti... | 08/04/2009 |
| 7569397 | Immunoassay devices and use thereof An immunoassay device has a housing defining a first opening for receiving a solution and a second opening through which a liquid sample is deposited, a strip of sorbent material having a test site with immobilized antigen or antibody for the ligand to be tested, an... | 08/04/2009 |
| 7566572 | Immunological assay and chip The present invention provides an immunological assay suitable to be carried out on a chip. After an antigen-antibody complex in which an antigen to be measured and an antibody have bound to each other was obtained in a reaction chamber, the reaction chamber is wash... | 07/28/2009 |
| 7547557 | Directed-flow assay device A diagnostic assay device that directs an applied sample to the analytical membrane of a directed flow device. The device has a sample receiving port defined by layers of built-up material on one end of the test strip. The port contains the sample and specifically d... | 06/16/2009 |
| 7541194 | Device for collection and assay of oral fluids A device for collecting and transporting aqueous fluid from the oral cavity to a lateral chromatographic strip for test is disclosed. The lateral chromatographic strip is placed within and extend along a cavity defined in a housing. At least one inspection site to t... | 06/02/2009 |
| 7521259 | Assay test strips with multiple labels and reading same In one aspect, an assay test strip includes a test label that specifically binds a target analyte and a control label that is free of any specific binding affinity for the target analyte and has a different optical characteristic than the test label. In another aspe... | 04/21/2009 |
| 7521260 | Assay test strips and reading same An assay test strip includes a flow path, a sample receiving zone, a label, a detection zone that includes a region of interest, and at least one position marker. The at least one position marker is aligned with respect to the region of interest such that location o... | 04/21/2009 |
| 7491551 | Quantitative lateral flow assays and devices This invention provides solid phase specific binding lateral flow assay methods, devices and kits for quantitating high and low molecular weight analytes. The methods and devices of the invention employ labelled reagents which are either analyte analogs or complemen... | 02/17/2009 |
| 7488606 | Collection device for lateral flow chromatography A device for collecting oral liquids includes a lateral flow chromatography strip having a collection member. The collection member is separated from the remainder of the chromatography strip by a liquid impermeable removable barrier which prevents liquid in the col... | 02/10/2009 |
| 7476549 | Laser-induced fluorescence detection device and method Disclosed is a lateral flow quantitative assay method which can measure one or more analyte species at the same time, with high sensitivity. Also, the present invention relates to a strip which can measure one or more analyte species at the same time, with high sens... | 01/13/2009 |
| 7476548 | Dry reagent strip configuration, composition and method for multiple analyte determination An assay device, analytical instrument and assay method for determining the presence or amount of an analyte in a fluid is disclosed. The device is a one-step lateral flow dry reagent immunoassay with one, two or more zones along a transverse axis of the device, eac... | 01/13/2009 |
| 7473563 | Environmental sampling and testing device Provided is sampling and testing device for the detection of specific molds, allergens, viruses, bacteria, fungi, and other protein containing substances. Embodiments of the device include a sampling member slideably engaged with a base that contains a lateral flow ... | 01/06/2009 |
| 7473562 | Method for high-throughput integrated chemical and biochemical reactions The present invention relates to methods for monitoring in a high through-put fashion a multitude of molecular reaction processes, using a substrate, said substrate comprising a plurality of micro-channels, wherein each micro-channel has inlet and outlet open ends o... | 01/06/2009 |
| 7465587 | Diagnostic assay device This invention relates to assays for an analyte in a liquid sample such as a body fluid. More particularly, the invention relates to a method and apparatus for the detection of a ligand in a body fluid such as urine or blood, which includes an immobilization zone fo... | 12/16/2008 |
| 7459314 | Lateral flow immunoassay controls Rapid lateral flow immunoassays have an extensive history of use in both the clinical and home settings. These devices are used to test for a variety of analytes, such as drugs of abuse, hormones, proteins, urine or plasma components and the like. The present invent... | 12/02/2008 |
| 7449343 | Method for measuring surface plasmon resonance It is an object of the present invention to provide a measurement method which can suppress noise when a specific binding reaction between a physiologically active substance and a test substance is measured using a surface plasmon resonance measurement device. The p... | 11/11/2008 |
| 7445941 | Diagnostic devices and apparatus for the controlled movement of reagents without membranes The assay devices, assay systems and device components of this invention comprise at least two opposing surfaces disposed a capillary distance apart, at least one of which is capable of immobilizing at least one target ligand or a conjugate in an amount related to t... | 11/04/2008 |
| 7442557 | Bi-directional flow assay device with reagent bridge A device for conducting an assay to determine the presence or amount of an analyte in a fluid sample. The device includes a flow path that facilitates fluidic flow by capillary action. The flow path has a first fluid permeable region, a second fluid permeable region... | 10/28/2008 |
| 7432111 | Non-continuous immunoassay device and immunoassay method using the same A non-continuous immunoassay device which includes two or more separated pads for immunoassay analysis, and is capable of controlling the migration speed of a mobile phase between the separated pads, and an immunoassay method using the same are disclosed. The immuno... | 10/07/2008 |
| 7427511 | Immunochromatographic test device An immunochromatographic test device of the present invention comprises: a sample receiving member for receiving a sample; a label holding member for holding a labeling substance to bind to an analyte contained in the sample; and a chromatographic membrane having a ... | 09/23/2008 |
| 7419784 | Methods, systems and apparatus for separation and isolation of one or more sample components of a sample biological material Devices, systems and methods for use in separating sample materials into different sample components and then isolating one or more of the sample components for further processing or analysis are disclosed. Devices employ configurations that optionally allow a sampl... | 09/02/2008 |
| 7413880 | Test kit for immunochromatography A test kit for immunochromatography comprising a test strip and a test tube is described. The test strip comprises a detection zone for detecting an analyte in a sample. The test tube accommodates the test strip. The test tube comprises an indicator at a position co... | 08/19/2008 |
| 7410808 | Method and assay for detection of residues Embodiments described herein include methods and assays for detecting an analyte in a sample using a plurality of control zone capture agents. Some embodiments include detection of multiple analytes in a sample utilizing a plurality of analyte binders and a control ... | 08/12/2008 |
| 7407764 | Plasma C5A levels as an indicator of asthma severity This invention provides the first blood test which characterizes asthma severity. More specifically, the present invention provides methods of determining the severity of acute asthma in a patient by determining the levels of C5a or C5a-desArg in the patient's blood... | 08/05/2008 |
| 7407813 | Assays An analytical test device incorporating a dry porous carrier to which a liquid sample, eg. urine, suspected of containing an analyte such as HCG or LH can be applied indirectly, the device also incorporating a labelled specific binding reagent which is freely mobile... | 08/05/2008 |
| 7405054 | Signal amplification method for surface plasmon resonance-based chemical detection The present invention provides methods and compositions for amplifying the detection signal in surface plasmon resonance (SPR)-based flow systems. The signal amplification methods comprise the use of well established marker systems that provide a precipitate. The ma... | 07/29/2008 |
| 7393697 | Diagnostic test for analytes in a sample Diagnostic devices and methods are provided. The diagnostic devices preferably comprise a test strip with a test area. The sample to be analyzed contacts the test area, which comprises a specific binding partner for the analyte of interest. Analyte, if present in th... | 07/01/2008 |
