Did You Know...
...that Charles Goodyear performed some of his experiments on rubber while in debtor's prison? He was there so often he referred to it as his "hotel". Chronically in debt because of poor business sense and ill health, Goodyear depended on the generosity of friends and family. Even after he unlocked the secret to vulcanizing rubber, he was unable to improve his financial situation. When he died, his estate was $200,000 in debt.
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| Number | Title | Issue Date |
| 7842513 | Pregnancy detection This invention provides methods and compositions for testing for pregnancy and non-pregnancy in ungulates and non-hoofed ruminates. The tests provided by this invention are useful during a time that coincides with the estrus cycle during which breeding occurs or the... | 11/30/2010 |
| 7695977 | Assays for preimplantation factor and preimplantation factor peptides The present invention relates to assay methods used for detecting the presence of PIF, and to PIF peptides identified using this assay. In particular, the present invention relates to flow cytometry assays for detecting PIF. It is based, at least in part, on the obs... | 04/13/2010 |
| 7687281 | Bovine pregnancy test This invention provides bovine pregnancy test methods and devices. The test is also suitable for other ruminant and/or ungulate animals. Antigens from Group A (early pregnancy antigens), and/or Group B (mid-pregnancy antigens), and Group C (early, mid- and late preg... | 03/30/2010 |
| 7678582 | Assays for preimplantation factor and preimplantation factor peptides The present invention relates to assay methods used for detecting the presence of PIF, and to PIF peptides identified using this assay. In particular, the present invention relates to flow cytometry assays for detecting PIF. It is based, at least in part, on the obs... | 03/16/2010 |
| 7670851 | Assays for preimplantation factor and preimplantation factor peptides The present invention relates to assay methods used for detecting the presence of PIF, and to PIF peptides identified using this assay. In particular, the present invention relates to flow cytometry assays for detecting PIF. It is based, at least in part, on the obs... | 03/02/2010 |
| 7670850 | Assays for preimplantation factor and preimplantation factor peptides The present invention relates to assay methods used for detecting the presence of PIF, and to PIF peptides identified using this assay. In particular, the present invention relates to flow cytometry assays for detecting PIF. It is based, at least in part, on the obs... | 03/02/2010 |
| 7670852 | Assays for preimplantation factor and preimplantation factor peptides The present invention relates to assay methods used for detecting the presence of PIF, and to PIF peptides identified using this assay. In particular, the present invention relates to flow cytometry assays for detecting PIF. It is based, at least in part, on the obs... | 03/02/2010 |
| 7410768 | Test methods and devices A method and test device for differentiating between states of an analyte that can exist in different forms, such as follicle stimulating hormone (FSH). The method or test device uses a pair of specific binding agents, especially monoclonal antibodies, in two assays... | 08/12/2008 |
| 7410807 | Pregnancy and sex identification test based on saliva or other bodily fluids A method of testing an animal for pregnancy or sex identification comprising the steps of first, providing a first vessel containing a liquid and having a removable surface wherein said removable surface is at least partially coated with an antibody and then introdu... | 08/12/2008 |
| 7393696 | Bovine pregnancy test This invention provides bovine pregnancy test methods and devices. The test is also suitable for other ruminant and/or ungulate animals. Antigens from Group A (early pregnancy antigens), and/or Group B (mid-pregnancy antigens), and Group C (early, mid- and late preg... | 07/01/2008 |
| 7392140 | Cellular fibronectin as a diagnostic marker in stroke and methods of use thereof Methods for the diagnosis and evaluation of stroke and stroke sub-type employ a variety of bio-markers including cellular fibronectin (c-Fn) assembled as a panel for stoke diagnosis and evaluation. Methods are disclosed for selecting markers and correlating their co... | 06/24/2008 |
| 7364914 | Method for diluting a fluid and detecting analytes within a diluted fluid The present invention provides a method and device for processing, sampling, and diluting a fluid and for detecting an analyte within the processed, sampled, and diluted fluid. In the method and device for processing, sampling, and diluting a fluid, an amount of flu... | 04/29/2008 |
| 7332350 | Diagnostic device for distinguishing between normal and ectopic pregnancy and method for preparing the same A one-step diagnostic device for simultaneously detecting and distinguishing between a normal pregnancy and an ectopic pregnancy and methods for preparing the device are disclosed. Utilizing the device and principles of the present invention, normal pregnancy and ec... | 02/19/2008 |
| 7326536 | Agents for treatment of HCV and methods of use An amphipathic helix at the approximate N-terminus of Hepatitis C virus (HCV) nonstructural proteins mediates the association of these proteins with cytoplasmic membranes in infected cells. This association is essential for replication. Thus, assessing the ability o... | 02/05/2008 |
| 7323346 | Screening for gestational disorders The invention relates to methods and compositions for identifying pregnant subjects having, or predisposed to having, gestational diabetes, preeclampsia, and gestational hypertension. The methods are applicable to urine and/or blood samples and can be conducted prio... | 01/29/2008 |
| 7300633 | Specimen collection container The present invention recognizes that sample handling devices, particularly those used for testing for substances of abuse, do not allow for a separation of the bulk sample from a sample thereof to be tested. The present invention provides such a device and methods ... | 11/27/2007 |
| 7270959 | Specimen collection container The present invention recognizes that sample handling devices, particularly those used for testing for substances of abuse, do not allow for a separation of the bulk sample from a sample thereof to be tested. The present invention provides such a device and methods ... | 09/18/2007 |
| 7270970 | Point of care diagnostic systems Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and operating rooms, or in any situation in which a rapid and accurate res... | 09/18/2007 |
| 7258990 | Alleviation of non-specific binding in microarray assays A post-incubation treatment is employed to effectively remove targets, such as proteins/protein complexes, or other label-bearing moieties that may non-specifically bind to a microarray substrate during a binding assay. Following incubation, a one-step wash is carri... | 08/21/2007 |
| 7238538 | Chromatographic assay device and methods A chromatographic assay device for the analysis of an analyte in a liquid sample has a proximal sample application zone and a distal test zone. The test zone contains a first ligand capable of binding with the analyte to form an analyte-ligand complex. The device al... | 07/03/2007 |
| 7232661 | Diagnostic agents for the prenatal diagnosis of preterm delivery, fetal infection, and fetal damage, and diagnostic kit containing the same This invention is about a method for the prenatal diagnosis of preterm delivery, fetal infection, and fetal damage, and diagnostic reagent system and diagnostic kit for the diagnosis. The method, diagnostic reagent system, and kit are based on the finding that the l... | 06/19/2007 |
| 7228295 | Methods for selecting, developing and improving diagnostic tests for pregnancy-related conditions Decision-support systems, such as neural networks, for assessing the risk of delivery within a predetermined time or the likelihood of preterm delivery are provided. ... | 06/05/2007 |
| 7211269 | Cosmetic or dermatological use of peptides for promoting adhesion between skin cells Method for preparing a cosmetic or dermatological composition, of a sufficient amount of peptides of sequence (Gly-Pro-Gln)n-NH2, wherein: n ranges between 1 and 3, and the amino acids can be in the form L, D or DL; the peptides or the composit... | 05/01/2007 |
| 7211444 | Waveguide and assay A fluidic waveguide comprising a container and a fluid that fills said container, wherein said fluid has a refractive index greater than the refractive index of the wall of said container and wherein said fluid can act as a waveguide for electromagnetic radiation wh... | 05/01/2007 |
| 7208292 | Nucleic acid encoding an interleukin-9 receptor variant This invention relates to the diagnosis, treatment and methods for discovery of new therapeutics for atopic asthma and related disorders based on variants of Asthma Associated Factor 2. One embodiment of the invention is a variant of AAF2 wherein codon 173 is delete... | 04/24/2007 |
| 7179640 | Method and apparatus for detecting conception in animals The present invention provides antibodies which specifically bind early conception factor, which can be found in body fluids of animals including but not limited to the cow, cat, dog, horse, human, sheep, and pig. The invention provides methods for detecting concept... | 02/20/2007 |
| 7179660 | Carriers coated with polysaccharides, their preparation and use A polysaccharide coated carrier having a coating of at least two successive layers of polysaccharide. The first polysaccharide layer spontaneously associates with a second polysaccharide layer and, optionally, the carrier. Each successive layer of polysaccharide spo... | 02/20/2007 |
| 7125728 | Determination of pregnancy status in cattle and sheep A method and kit for determining whether an animal is not pregnant, or is pregnant following a breeding. The level of expression of a pregnancy induced protein is determined in an animal for which pregnancy status information is desired and the level is compared to ... | 10/24/2006 |
| 7109042 | Assays An analytical test device useful for example in pregnancy testing, comprises a hollow casing (500) constructed of moisture-impervious solid material, such as plastics materials, containing a dry porous carrier (510) which communicates indirectly with t... | 09/19/2006 |
| 7101682 | Simultaneous screening of multiple analytes Methods, compositions and kits are disclosed. The methods are directed to determining the presence of one or more analytes in a sample suspected of containing any one of a plurality of the analytes. A combination is provided comprising in a medium (i) the sample, (i... | 09/05/2006 |
| 7090802 | Sampling assembly for simultaneously testing a liquid biological sample for a plurality of hormones and method thereof A sampling assembly for simultaneously testing a liquid biological sample for a plurality of hormones and method thereof are described. A sampling membrane includes a dry porous carrier having a proximal end narrower than a distal end and forming a unidirectional li... | 08/15/2006 |
| 7090984 | Device and method for detecting substance A method for detecting a substance, comprising developing a developing liquid through a test region up to a reference region, and a detection device for use therein, wherein the reference region comprises a metal compound other than an alkali metal salt, and the dev... | 08/15/2006 |
| 7074576 | Protein biopolymer markers indicative of alzheimer's disease The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopoly... | 07/11/2006 |
| 7056698 | Nucleic acids encoding interleukin-9 receptor variants This invention relates to the diagnosis, treatment and methods for discovery of new therapeutics for atopic asthma and related disorders based on variants of Asthma Associated Factor 2. One embodiment of the invention is a variant of AAF2 wherein codon 173 is delete... | 06/06/2006 |
| 7045342 | Diagnostic detection device and method The invention provides an improved test cell for detecting the presence of an analyte in a liquid sample. The device has an elongate casing defining a liquid sample inlet, a reservoir volume, a test volume, and a window through the casing at the test volume. Dispose... | 05/16/2006 |
| 7033775 | Simultaneous screening of multiple analytes Methods, compositions and kits are disclosed. The methods are directed to determining the presence of one or more analytes in a sample suspected of containing any one of a plurality of the analytes. A combination is provided comprising in a medium (i) the sample, (i... | 04/25/2006 |
| 7029866 | Cancer diagnosis by the measurement of Nup88 in body samples The invention is directed to a method of diagnosis of the existence and/or the pathological developmental stage and/or the grade of malignancy of carcinomas and/or sarcomas in mammals characterized by the preparation of a body sample of said mammals and the determin... | 04/18/2006 |
| 7008775 | Diagnostic method for screening complement regulatory protein levels to predict spontaneous abortion The invention provides a method for the early detection of pregnancy failure, spontaneous abortion or premature birth by determinations of complement regulatory protein levels. A kit for use in rapid identification of these pregnancy complications is also provided. | 03/07/2006 |
| 6998243 | Biopolymer marker indicative of disease state having a molecular weight of 1793 daltons The instant invention involves the use of a combination of preparatory steps in conjunction with mass spectroscopy and time-of-flight detection procedures to maximize the diversity of biopolymers which are verifiable within a particular sample. The cohort of biopoly... | 02/14/2006 |
| 6960445 | Determination of endometrial receptivity toward embryo implantation Methods of diagnosing infertility in a mammal that include detecting the presence and level of a β3 integrin subunit in an endometrium sample of a mammal at a plurality of stages of the endometrial cycle and correlating delayed appearance or a reduced le... | 11/01/2005 |
