"The abolishment of pain in surgery is a chimera. It is absurd to go on seeking it...knife and pain are two words in surgery that must forever be associated in the consciousness of the patient."
Dr. Alfred Velpeau, French surgeon ; 1839
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| Number | Title | Issue Date |
| 8178350 | Method and apparatus for automated rapid immunohistochemistry A method of biochemical processing may, in certain embodiments, involve the steps of use of a consumable biochemical process element and a consumable biochemical process alterable information memory element associated therewith, such as a substance withdrawal consum... | 05/15/2012 |
| 8158431 | Remote control system The objective of the present invention is to provide a remote control method which allows a technician, etc. in a support center to remote-control a clinical specimen processing device, and a remote control system, a status informing device and a control apparatus u... | 04/17/2012 |
| 8105837 | Method for automatic assay of anionic detergents in seawater A method for assaying anionic detergents in seawater comprises: (1) flow a sample through a sample system and an analysis-detection system; flow a reference solution through a reference system, a valve, and the analysis-detection system; where the sample and referen... | 01/31/2012 |
| 8080422 | Method of generating a fluid stream in a microfluidic device A method of continuously regulating external gas pressure on a variable volume container for the delivery of fluids to a microfluidic device and analysis of particles based upon relative presence or absence of at least one particle characteristic. ... | 12/20/2011 |
| 8075852 | System and method for bubble removal In one aspect of the invention, systems, methods, and devices are provided for handling liquid. In some embodiments, such systems, methods, and devices are used to combine fluids while removing gaseous bubbles. ... | 12/13/2011 |
| 8058072 | Microanalysis measuring apparatus and microanalysis measuring method using the same This invention provides a measuring apparatus for microanalysis, which can be simply manufactured and can realize a number of analyses and measurements in a small analyte amount and particularly can analyze and measure a number of analytes having different concentra... | 11/15/2011 |
| 8030080 | Systems and methods for processing samples in a closed container, and related devices A system and method for automated processing of nucleic acids and other samples includes a disposable container comprising a tray and a flexible barrier. The barrier is configured to seal with a top edge of the tray, providing a closed, aseptic work area within the ... | 10/04/2011 |
| 8026101 | Failure detection in automated clinical analyzers The invention is a method for detecting failures in an analyzer for conducting clinical assays. Potential errors that can result in assay failures in an analyzer are identified, as are their potential sources. The probability that an error source so identified will ... | 09/27/2011 |
| 8021884 | Detecting bacteria by direct counting of structural protein units or pili by IVDS and mass spectrometry A system and method for detecting the presence of submicron sized particles in a sample taken from the environment. More particularly, the system may be used to detect and identify bacteria by detecting the presence of bacterial pili which have been separated from b... | 09/20/2011 |
| 7998741 | Remote control system The objective of the present invention is to provide a remote control method which allows a technician, etc. in a support center to remote-control a clinical specimen processing device, and a remote control system, a status informing device and a control apparatus u... | 08/16/2011 |
| 7960178 | Enhanced scheduling sample processing system and methods of biological slide processing A sample processing system 101 that may be automated and methods are disclosed where sample(s) 198 are arranged on a carrier element 197 and a process operation control system 171 automatically processes the sample(s) perhaps robotically ... | 06/14/2011 |
| 7951597 | Pressurized fluid sample injector and method of injecting fluid samples The present invention is a pressurized fluid sample injector system consisting of a sample needle, multiport valve, sample loop, metering syringe and a pressure assist pump. The speed of sample transport into the sample loop is increased by pressurizing the fluid in... | 05/31/2011 |
| 7935534 | Automated molecular pathology apparatus having fixed slide platforms Apparatus and methods for automatically staining or treating multiple tissue samples mounted on slides are provided, in which the slides and reagent bottles are held in fixed position, and the reagent, wash and coverslipping solutions brought to the slides. Alternat... | 05/03/2011 |
| 7736901 | Apparatus and method for assaying coagulation in fluid samples This invention is a disposable cartridge for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge, in use with an electronic analyzer allows a fluid sample to be metered and quantitatively ... | 06/15/2010 |
| 7732212 | Method of management of analytical data and system for management of analytical data A communication unit (12) of a service center (10) transmits and receives information such as analysis information to and from a plurality of automatically analyzing apparatuses (100). A database (16) stores the information such as the an... | 06/08/2010 |
| 7662630 | Method for verifying the integrity of thermal desorption sampling tubes An analyte of a sample is transferred to an analytical instrument by introducing a quantity of a compound of a standard material into a vessel containing an adsorbent material; introducing a quantity of the analyte of the sample into the vessel; and transferring the... | 02/16/2010 |
| 7645611 | Device and method for micro sorbent extraction and desorption This invention relates to a micro cartridge and to a method of using the micro cartridge to sample and extract components of interest from a gas or a liquid. The cartridge contains a sorbent and has passages through which a pressure drop can be created to permit acc... | 01/12/2010 |
| 7582481 | Method of multiple reaction in microreactor, and microreactor When fluids A and B are caused to flow together from a fluid introduction portion into a microreactionchannel, they are divided into a plurality of fluid segments A and B in a diametral section of the microreactionchannel at the entrance side, and are mixed with eac... | 09/01/2009 |
| 7579190 | Method and apparatus for preparing cytological specimens An automated system for preparing a plurality of cytological specimens from a plurality of fluid samples in vials includes an apparatus for collecting a monolayer of cells from each sample and transferring the cells to a microscope slide for fixing, staining, and in... | 08/25/2009 |
| 7534617 | Methods for avoiding contamination of negative sample material with analyte-containing samples when using pipetting robots A method is disclosed for reducing the contamination of reaction containers which are empty or already fitted with analyte-free sampling material or sampling material having a low analyte concentration, inside a configuration of reaction containers which are spatial... | 05/19/2009 |
| 7479390 | Device and method for micro sorbent extraction and desorption This invention relates to a micro cartridge and to a method of using the micro cartridge to sample and extract components of interest from a gas or a liquid. The cartridge contains a sorbent and has passages through which a pressure drop can be created to permit acc... | 01/20/2009 |
| 7476543 | Device and method for wetting objects The invention relates to a device and a method for moistening objects with a liquid by means of a system (1) for carrying a specimen slide that is disposed at a distance from a platform (7). To reduce liquid consumption, the specimen slide is raised or... | 01/13/2009 |
| 7442339 | Microfluidic apparatus, Raman spectroscopy systems, and methods for performing molecular reactions Disclosed herein are methods, apparatuses, and systems for performing nucleic acid sequencing reactions and molecular binding reactions in a microfluidic channel. The methods, apparatuses, and systems can include a restriction barrier to restrict movement of a parti... | 10/28/2008 |
| 7438856 | Microfluidic devices and methods Embodiments of the invention are directed to microfluidic devices. In one embodiment, a microanalysis chip comprises a body having at least one transfer-separation channel with a channel bottom that has a bottom opening. The transfer-separation channel terminates in... | 10/21/2008 |
| 7435602 | Reducing effects of spectral nonuniformity Method and system providing calibration of light detected from biological samples with a correction factor including components for each of a plurality of spectrally distinguishable species and/or for each well and/or for each filter. ... | 10/14/2008 |
| 7434513 | Flexible high density array print head with systems and methods for aligning pin plate, reservoir and substrate with respect to each other Systems and methods for aligning High Density Array (“HDA”) pin plates, substrates and reservoirs with respect to each other. The system includes a flexure having a flexible print head, elongated members flexibly connected off-axis to the system and a pin plate ... | 10/14/2008 |
| 7435382 | Incubator An incubator includes a rotating incubator rotor. The incubator rotor is provided with a plurality of element chambers which are arranged along the outer periphery of the incubator rotor and each of which accommodates a dry analysis element spotted with a sample and... | 10/14/2008 |
| 7435598 | Catalyst testing apparatus and process An apparatus and process are described in which a plurality of preloaded catalyst samples tubes can be serially and automatically moved from a support to a reaction zone where each catalyst sample can be heated and a preheated reagent feed contacted with the sample ... | 10/14/2008 |
| 7435599 | Method and apparatus for preparing cytological specimens An automated system for preparing a plurality of cytological specimens from a plurality of fluid samples in vials includes an apparatus for collecting a monolayer of cells from each sample and transferring the cells to a microscope slide for fixing, staining, and in... | 10/14/2008 |
| 7435383 | Automated tissue staining system and reagent container An automated staining system and a reagent container designed for use with the automated staining apparatus. The reagent container includes a reagent containment section capable of containing a volume of a reagent. The reagent containment section includes an upper w... | 10/14/2008 |
| 7431889 | Inner walls of microfluidic devices A microfluidic device comprising one, two, three or more enclosed microchannel structures, each of which comprises a) an inlet arrangement with an inlet opening for liquid, b) a reaction microcavity (RM1) downstream to the inlet opening, and c) an upstrea... | 10/07/2008 |
| 7429358 | Method and apparatus for measuring gas sorption and desorption properties of materials The invention relates to a method and an apparatus (herein referred to as a “gas sorption/desorption analyzer”) for measuring the gas sorption properties of substances (for example hydrogen sorption by metal alloys). Measurements include: Pressure Composition Te... | 09/30/2008 |
| 7425254 | Fractionation of macro-molecules using asymmetric pulsed field electrophoresis A method and apparatus for fractionation of charged macro-molecules such as DNA is provided. DNA solution is loaded into a matrix including an array of obstacles. An alternating electric field having two different fields at different orientations is applied. The alt... | 09/16/2008 |
| 7419636 | Vapor sensing instruments for ultra trace chemical detection A detector for detecting vapors emitted from analytes includes a housing, a pump and a sensing assembly. The housing has an inlet, an outlet and an enclosed sensing volume therebetween. The pump communicates with the housing for moving a carrier sequentially through... | 09/02/2008 |
| 7419639 | Multilayer microfluidic device The present invention provides microfluidic devices constructed from four layers. The layers include a rigid substrate layer, a patterned rigid layer having thickness t, a patterned elastomeric layer having thickness greater than t, and a rigid support layer. Microf... | 09/02/2008 |
| 7419835 | Screening for ligand binding at specific target sites A method for screening of compounds for binding differentiation at various drug target binding sites is used with a device measuring the enthalpy of reaction for the binding. The method includes merging test ligand with target compound and merging test ligand with t... | 09/02/2008 |
| 7416699 | Carbon nanotube devices Nanotubes and nanotube-based devices are implemented in a variety of applications. According to an example embodiment of the present invention, a nanotube is adapted to pass current between two conductive elements. In one implementation, each conductive element incl... | 08/26/2008 |
| 7416703 | Polymer based lanthanide luminescent sensors for the detection of organophosphorus compounds A device for measuring and detecting the organophosphonis compounds, such as a pesticides or a nerve agents is provided. The devices function by selectively binding an organophosphorous compound to a luminescent functionality-imprinted copolymer. The copolymers poss... | 08/26/2008 |
| 7416897 | Method for high-throughput screening assay sample preparation and analysis A method is disclosed for high-throughput screening assay sample preparation and testing for the identification of binding between drug targets and library compounds, for use with a calorimetric device measuring the enthalpy of reaction for the binding. The method i... | 08/26/2008 |
| 7416903 | Wavy interface mixer The present invention provides methods and apparatus for mixing samples in-line in a microfluidic system, comprising methods of and means for introducing a first fluid sample into a flow-tube at a first end at a first velocity via a first conduit; methods of and mea... | 08/26/2008 |