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Class 436/18 - Preservative, buffer, anticoagulant or diluent


Subclass of Class 436 - Chemistry: analytical and immunological testing
Definition: Compositions which are added to a sample for a chemical
No. of patents: 449
Last issue date: 05/22/2012


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NumberTitleIssue Date
4843013Multiple control standard for blood analysis
This invention discloses a multiple control standard for the use in the quality assurance of blood analysis instrumentation systems. The liquid control standard is able to act as a control standard for blood gas instrumentation systems measuring pH, pCO2 ...
06/27/1989
4833090Preservation of glucose in blood
Inclusion in a blood sample of an isomer of glucose which is capable of replacing glucose in blood cell metabolism ensures accuracy of glucose assay....
05/23/1989
4806486Calibration liquid for ion-specific electrodes, process for preparing them and their application
A calibration liquid, especially suitable for ion-selective electrodes, containing albumin. This solution is stable and prevents errors by junction potentials or unknown complexing with calcium....
02/21/1989
4793987Stabilized radiolabelled compounds
A stabilizer for radioactively labelled organic compounds has the general formula ##STR1## where R is C1 to C4 alkylene which may be OH substituted, m is 0 or 1 (i.e. R may be absent or present), X is carboxyl or sulphonyl e.g. COOH or SO3
12/27/1988
4784960Process for preparation of control for use in progesterone receptor
A process is disclosed for producing steroid hormone receptor samples to be utilized as controls during assays of various human tissue for steroid hormones, especially estrogen and progesterone. The process comprises collecting tissue known to include suc...
11/15/1988
4782026Collection medium for whole blood
An inhibitor of Platelet Factor 3 activity is included in a collection medium into which a whole blood sample is a collected. The inhibitor of Platelet Factor 3 activity, it has been discovered, prevents an initial drop in the activated clotting time meas...
11/01/1988
4782023Stabilized horseradish peroxidase conjugate composition
An enzyme conjugate composition comprising an enzyme conjugate, a calcium salt and a polyethylene glycol is disclosed. The enzyme conjugate composition is effectively stabilized by the presence of the calcium salt and the polyethylene glycol....
11/01/1988
4780419Method of inhibiting glycolysis in blood samples
There is described a method of inhibiting glycolysis in blood samples by adding an acid to the blood sample to adjust pH of the blood to a level between 5.0 and 7.0. Collected blood samples undergo glycolysis during storage due to progress of the reaction...
10/25/1988
4777139Hematology control or calibrator with red cell components of enhanced stability
Red cells are exposed to an unsaturated aldehyde such as acrolein (propenal) under conditions sufficient to increase the stability of the cells without impairing the ability of a lysing reagent to lyse the cells. After treatment, the treated cells are was...
10/11/1988
4755461Tableted blood plasma microconcentrated thromboplastin coagulation reagent
The invention herein is directed to an improved thromboplastin composition wherein the thromboplastin is supplied in a tablet separate from calcium salts in order to stabilize the thromboplastin....
07/05/1988
4753888Multiple control standard for blood analysis
This invention discloses a multiple control standard for the use in the quality assurance of blood analysis instrumentation systems. The liquid control standard is able to act as a control standard for blood gas instrumentation systems measuring pH, pCO2 ...
06/28/1988
4745071Method for the volumetric differentiation of blood cells types
Improved reagents and methods for obtaining distinct volumetric differentiation of platelets, erythocytes and certain leukocyute subpopulations are disclosed. 1,3-dimethylurea is disclosed as a cell stabilizing agent for use in the blood diluent reagent. ...
05/17/1988
4731330Whole blood control sample
A whole blood control sample and a method of preparing the sample are disclosed. The method comprises collecting a whole blood sample from one or more donor, separating each sample into red blood cells and plasma, fixing the red blood cells, mixing the fi...
03/15/1988
4729959Glucose reference control for glucose test strips
A stable glucose reference control has been found in which the true value and the measured value of glucose in blood, colorimetrically obtained with glucose test strips, is approximately the same. The glucose reference control comprises an aqueous suspens...
03/08/1988
4727042Calibrator composition and method of producing and using same for veterinary applications
Disclosed are a calibrator composition and method of producing and using the same in the analysis of blood of a particular species. From whole blood of the particular species, a solution is derived with which semi- and fully-automated particle counters ca...
02/23/1988
4722904Thermodynamically-stable aqueous perfluorocarbon microemulsion useful as blood gas control or calibrator
The present invention relates to aqueous perfluorocarbon emulsions and particularly microemulsions, and to their use as blood gas controls and calibrators....
02/02/1988
4716119Control serum and process therefor
Control serum containing (1) at least one compound of the formula: ##STR1## in which T is hydrogen or methyl, hydroxymethyl or methoxymethyl X is hydrogen hydroxymethyl or methyl when Y is hydroxyl, hydroxymethyl or NR2 ; Y is hydrogen, hydroxy...
12/29/1987
4704352L-ascorbate-2-phosphate salts in blood cell storage
A solution for blood cell storage having sugar-containing blood cell nutrients therein and additionally containing a magnesium or calcium L-ascorbate-2-phosphate salt is taught. The magnesium and calcium L-ascorbate-2-phosphate salts remain stable below p...
11/03/1987
4704365Composition and method for stabilization of dinucleotides
A reduced dinucleotide, preferably nicotinamide adenine dinucleotide (NADH), is stabilized in an aqueous base liquid containing propylene glycol, boric acid and a buffer capable of buffering within a pH range of 8-11. The stabilized liquid contains greate...
11/03/1987
4701417Control or calibration serum for lipid diagnosis
The present invention provides a control or calibration serum for lipid diagnosis, wherein it contains the parameters relevant for lipid diagnosis in the normal or pathological concentration range in a single storage-stable form. The present invention als...
10/20/1987
4693912Lyophilization of reagent-coated particles
A method of lyophilizing reagent-coated latex particles which results in a product easily reconstituted without agglutination, retains activity, and remains stable and active at storage at 4° C....
09/15/1987
4689308Article for preparing a chemical sensor for use
The article includes a first vial (12) which is positioned within a second larger vial (32). The first vial (12) separately contains a first fluid, such as a first calibrating fluid, and the second vial (32) contains a second fluid, such as a second calib...
08/25/1987
4684615Stabilized isoenzyme control products
Isoenzyme control reagents and methods for making same stabilized by means of plexiform stabilizing means. The preferred plexiform stabilizing means is selected from the group consisting of monosaccharide and disaccharide reducing sugars. The most preferr...
08/04/1987
4677075Urobilinogen control
A stable control solution is provided for the determination of urobilinogen. The control solution comprises an aqueous solution of about 3-12% ethylene glycol, about 0.1% protein and preferably about 40-400 mg/dl urobilinogen, said composition buffered to...
06/30/1987
4668618Nuclear isolation medium and procedure for separating cell nuclei
Nuclear isolation media and procedures are described for dissociating discrete, non-agglomerated cell nuclei from animal tissue without the need to use enzyme treatments, centrifugation or the like in order to achieve the desired separation. The media fac...
05/26/1987
4663295Estrogen-progesterone control reagents and methods for making same
Reagents useful for steroid receptor assays containing both progesterone and estrogen receptors and methods. The reagents of the instant invention contain both estrogen and progesterone receptors in a stabilized format. A preferred embodiment includes tar...
05/05/1987
4640897Immunoanalysis of basophil-containing blood fraction for diagnosing parasitoses and allergies
The reagent is constituted by a suspension of basophil granulocytes bearing specific IgE's, containing from 300 to 1000 basophils per mm3. This suspension is obtained from a blood sample taken from a human or animal patient, by means of a liqui...
02/03/1987
4637986Flow cytometry lysing reagent with leukoprotective agent for producing a 3-part WBC count
Lysing reagents for use in flow cytometry instruments. Lysing reagents suitable for lysing red blood cells are provided thereby permitting 3-part differential counting of white blood cells. The reagents comprise a leukoprotective agent for preserving the ...
01/20/1987
4632907Preservative solution for fixed avian erythrocytes for the viral hemagglutination test
A preservative solution for fixed avian erythrocytes for the viral hemagglutination test of this invention comprises purified water which may contain serum albumin, glycerol or dimethyl sulfoxide and, additionally, a preventive against the growth of bacte...
12/30/1986
4626511Composition for reducing turbidity in samples of biological fluids
A composition which reduces the turbidity of samples of artificial or naturally occurring biological fluids comprising: a buffering agent; a nonionic surfactant; alpha-cyclodextrin; a lipase; and water. The composition provides a catalyst for and agents which hydro...
12/02/1986
4626512Standard solution for simultaneously calibrating a plurality of ion electrodes
A standard solution for simultaneously calibrating a plurality of ion electrodes for determining a plurality of ion electrodes for determining a plurality of ions including at least potassium ions and calcium ions in blood, the improvement wherein the con...
12/02/1986
4617275Reagent for blood analysis
A reagent for blood analysis comprises, as a lysing reagent for leukocyte count, tetradecyltrimethylammonium bromide and/or hexadecyltrimethylammonium chloride, dodecyltrimethylammonium chloride, and citric acid. This reagent is characterized by showing t...
10/14/1986
4595524Two component stain composition for producing a Giemsa blood stain effect
Disclosed is a novel, 2 component Giemsa stain. The stain comprises a first component which is an aqueous solution of methylene blue, Azure B and a preservative and a second component which is an acetone/dimethyl formamide/water solvent system containing ...
06/17/1986
4590164Process for the preparation of a glucose-free hemoglobin standard
A process for the preparation of a glucose-free glycosylated hemoglobin standard in which hemoglobin with a known content of glycosylated hemoglobin HbAIa+b+c is converted to cyanmethemoglobin by means of a K3 (FeCN)6 /KCN...
05/20/1986
4572899Aqueous solution for suspending and storing cells, especially erthrocytes
An aqueous solution for suspending and storing cells, especially erythrocytes, and containing sodium chloride, glucose or fructose, adenine, and a sugar alcohol, the sugar alcohol being sorbitol or xylitol is employed to further improve the storage time a...
02/25/1986
4555348Liquid buffer system
Monosodium phosphate is highly soluble in water and can be used as an ingredient for a low pH liquid buffer in a concentration of about 13-40 percent by weight. Tri potassium phosphate has good solubility in water and is a suitable ingredient for a high p...
11/26/1985
4529705Reagent for combined diluting and lysing whole blood
An improved reagent provides combined diluting and lysing of whole blood for use in instruments performing electronic blood cell counting and hemoglobin determination. The reagent prevents platelet aggregation and improves the accuracy of the white blood ...
07/16/1985
4528274Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
A method and reagent system is described for differential determination of more that one class of leukocyte populations, using an automatic blood cell analyzer. The reagent system includes a blood diluent and stromatolyzing reagent. The blood diluent is a...
07/09/1985
4521518Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
An isotonic multipurpose blood diluent, and a method for use of this diluent with a weak lysing reagent system which is especially suitable for routine enumeration of traditional hemogram values, and also the determination of lymphoid-myeloid populations ...
06/04/1985
4493821Preservative and fixative preparations for biological systems
A fixative composition for histological, cytological, immunological and proteinaceous preparations comprising a mixture of pyrrolid-2-one, a polyol, a urea and a zinc salt of a non-oxidizing organic or inorganic acid. Also disclosed are devices utilizing ...
01/15/1985
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