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...Daniel Webster invented a "bull plow" to pull out tree stumps. It didn't catch on because it was huge and required four oxen to pull it!
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| Number | Title | Issue Date |
| 7387898 | Apparatus and method for conducting assays A multi-well assay plate structure (54) and assay apparatus and a method for performing chemical biochemical assays is described. The multi-well assay plate structure (54) defines a relatively shallow substantially enclosed space (71) above a pl... | 06/17/2008 |
| 7387899 | Saliva sample collection system Test kit whereby the sponge portion of kit is used to swab saliva. The saliva is then extracted from sponge by either squeezing it out or through the use of a centrifuge. The sponge portion of the kit is attached to a collection container when used in the centrifuge... | 06/17/2008 |
| 7384792 | Method of fabricating nano-structured surface and configuration of surface enhanced light scattering probe A method to fabricate an optical scattering probe and the method includes the steps of a) depositing an conductive layer on a substrate followed by depositing a noble metal layer on top of the conductive layer and then an aluminum layer on top the noble metal layer;... | 06/10/2008 |
| 7384598 | Diagnostic device Diagnostic devices for detecting the presence of an analyte in a sample are provided. Devices of the present invention comprise a means for inducing a pressure differential on a sample to direct the sample to a test surface. In one embodiment, the means for inducing... | 06/10/2008 |
| 7381565 | Flow cytometers and detection system of lesser size Gas focusing flow cytometers are fabricatable employing simple and inexpensive manufacturing techniques. When such cytometers or conventional cytometers are combined with fiber optical light paths and laser diode and semiconductor photodetectors, light weight and ha... | 06/03/2008 |
| 7381374 | Immunoassay devices and methods of using same An immunoassay cartridge for sensing at least one analyte in a biological sample is disclosed. The immunoassay cartridge comprises a supporting plate, a reaction cavity made within the supporting plate and having at least one analyte-binding molecule immobilized the... | 06/03/2008 |
| 7381315 | Multi-channel analyte-separation device employing side-entry excitation A side-entry excitation arrangement is provided with a multi-channel analyte-separation device. In various embodiments, a plurality of channels are disposed in an array, with a laser disposed to direct an excitation beam of light along a beam path that crosses the l... | 06/03/2008 |
| 7372026 | System for repositioning a microfabricated cantilever A system for repositioning a microfabricated cantilever includes a microfabricated cantilever, a first device operable to detect a position of the microfabricated cantilever, and a second device. The first device is operable to determine an offset in the position of... | 05/13/2008 |
| 7371582 | Lateral flow quantitative assay method and strip and laser-induced fluorescence detection device therefor Disclosed is a lateral flow quantitative assay method which can measure one or more analyte species at the same time, with high sensitivity. Also, the present invention relates to a strip which can measure one or more analyte species at the same time, with high sens... | 05/13/2008 |
| 7371562 | Guided mode resonant filter biosensor using a linear grating surface structure Methods and compositions are provided for detecting biomolecular interactions. The use of labels is not required and the methods can be performed in a high-throughput manner. The invention also provides optical devices useful as narrow band filters. ... | 05/13/2008 |
| 7368084 | Flow cytometry for high throughput screening The present invention, provides a flow cytometry apparatus for the detection of particles from a plurality of samples comprising: means for moving a plurality of samples comprising particles from a plurality of respective source wells into a fluid flow stream; means... | 05/06/2008 |
| 7369331 | Fixed focus handy ovulation tester The present invention provides a fixed focus handy ovulation tester, the said ovulation tester comprising an inner casing (1), having a top and a bottom end; a controllable 5 illuminating assembly (2) located inside the inner casing and near the... | 05/06/2008 |
| 7364895 | Bioarray chip reaction apparatus and its manufacture A body 300 having a cavity 310 for mounting a substrate 120 fabricated with probe sequences at known locations according to the methods disclosed in U.S. Pat. No. 5,143,854 and PCT WO 92/10092 or others, is provided. The cavity includes inlets | 04/29/2008 |
| 7364906 | Products and methods for single parameter and multiparameter phenotyping of cells A method of single parameter and multiparameter characterizing of cells, particularly immunophenotyping of cells, is provided. The method preferably uses antibody-coated microspheres which are adapted to bind to specific types of cells. One or more sets of coated mi... | 04/29/2008 |
| 7355706 | Particle detection system implemented with an immersed optical system Fluid-based particle detection exhibits improved light collection and image quality from a light collection system that uses immersed optics on a flow-through cell for collecting and detecting scattered light from particles carried by the fluid. The flow-through cel... | 04/08/2008 |
| 7351589 | Products and methods for single parameter and multiparameter phenotyping of cells A method of single parameter and multiparameter characterizing of cells, particularly immunophenotyping of cells, is provided. The method preferably uses antibody coated microspheres which are adapted to bind to specific types of cells. One or more sets of coated mi... | 04/01/2008 |
| 7347617 | Mixing in microfluidic devices Mixing of liquids in a microfluidic device is accomplished by dispensing the liquids into a first chamber to produce combined liquid. The liquids are thereafter discharged through at least one capillary from the first chamber into a second chamber for complete mixin... | 03/25/2008 |
| 7347972 | Multiple analyte assay device A test device and associated method of use composed of a housing (100) defined by base (101) and cover (110). The base (101) has a closed end (104) and an open end (106). Slots (102a, 102b, etc.) ... | 03/25/2008 |
| 7317519 | Swept-angle SPR measurement system A swept-angle SPR measurement system deflects an optical beam over a range of deflection angles according to a control signal and maps the deflected beam to a target within a range of incidence angles that corresponds to the range of deflection angles. ... | 01/08/2008 |
| 7314596 | Apparatus for sensing coagulation of blood sample A blood sample sensing apparatus includes a moving device which moves a sample container containing a blood sample to a sensing position, a turning mechanism which is connected to the moving device and tilts the sample container such that a bottom of the sample cont... | 01/01/2008 |
| 7314749 | Method and apparatus for assay based on light diffraction The present invention relates to a method and apparatus for detecting analytes in a medium, and more particularly the present invention relates to an assay based on light diffraction which appears or changes upon the binding of analytes to their specific receptors l... | 01/01/2008 |
| 7315378 | Optical arrangement for assay reading device Disclosed, in one aspect, is an assay result reading device for reading the result of an assay performed using a test strip, the device comprising: a light source or sources, said light source/s emitting light incident upon at least two, spatially separated zones of... | 01/01/2008 |
| 7313257 | Handheld optical diagnostic device having image system array A self-contained, optical hand-held diagnostic device is provided with a body having a pocket-sized form factor sized and shaped for engagement by a user's hand. The body includes an integral power supply and an integral display. A channel receives reagent sample me... | 12/25/2007 |
| 7312089 | Detection of erythropoietin and erythropoietin receptor The invention is based on the development of several sensitive and simple methods for detecting erythropoietin and the erythropoietin receptor and associated antibodies. The methods and reagents are useful for differential diagnosis in Epo and EpoR related clinical ... | 12/25/2007 |
| 7312069 | Method of analyzing ligand in sample and apparatus for analyzing ligand in sample A sample analyzing method capable of high-precision analysis without being affected by vibration and optical design is provided. In the sample analyzing method, a sample containing a ligand is caused to bind to a receptor that can bind specifically to the ligand, an... | 12/25/2007 |
| 7309611 | Prewetting stop flow test strip A test strip and method for detecting an analyte present in a sample. The test strip comprising: a buffer addition zone to which a buffer may be added; an absorbent zone proximal to the buffer addition zone; one or more test zones distal to the buffer addition zone,... | 12/18/2007 |
| 7309607 | Method and device for monitoring platelet function The invention provides a method of monitoring platelet function in a mammal by passing blood removed from the body of the mammal through a passageway to contact an obstruction or irregularity in the passageway to generate a platelet mass in the passageway, and monit... | 12/18/2007 |
| 7309614 | Self-referencing biodetection method and patterned bioassays The invention relates to compositions and methods for detecting biomolecular interactions. The detection can occur without the use of labels and can be done in a high-throughput manner. The invention further relates to self-referencing colorimetric resonant optical ... | 12/18/2007 |
| 7304732 | Microelectromechanical resonant photoacoustic cell An integrated photoacoustic spectroscopy (PAS) cell is fabricated using microelectromechanical (MEMS) techniques. The multi-layer structure includes an inner layer with a patterned resonant cavity disposed between top and bottom outer layers and a microphone acousti... | 12/04/2007 |
| 7300633 | Specimen collection container The present invention recognizes that sample handling devices, particularly those used for testing for substances of abuse, do not allow for a separation of the bulk sample from a sample thereof to be tested. The present invention provides such a device and methods ... | 11/27/2007 |
| 7294502 | Device for collecting liquid samples The invention relates to a device for collecting samples of fluids, in particular of body fluids such as saliva, said device comprising an absorbent pad and two housing parts which are connected to the latter in a movable manner and can enclose the absorbent pad. Th... | 11/13/2007 |
| 7288413 | Combined chemical and immunochemical fecal occult blood test Methods for testing a fecal sample for the presence of hemoglobin, comprising performing a chemical fecal occult blood test on the sample and then performing an immunochemical fecal occult blood test on a portion of the sample exposed to the chemical reagents used i... | 10/30/2007 |
| 7285420 | System and method for self-referencing a sensor in a micron-sized deep flow chamber A system and method are described herein for self-referencing a sensor that is used to detect a biomolecular binding event and/or kinetics which occur in a sample solution flowing along side a reference solution in a micron-sized deep flow channel. ... | 10/23/2007 |
| 7285246 | Hand-held fluid analyzer A hand-held device detects the presence of a preselected substance in the breath. A deformable housing forms a test chamber for interacting an indicator reagent with the breath. An ampoule positioned inside the housing is ruptured by manual pressure through the wall... | 10/23/2007 |
| 7282367 | Method for verifying amount of sample solution, method for controlling measurement system and method for measuring concentration of solution in apparatus for measuring optical characteristic A verification method of a sample solution amount includes the steps of: detecting at least one of a transmitted light component, a scattered light component and a reflected light component of a light by a photosensor while irradiating a sample solution, which is be... | 10/16/2007 |
| 7270970 | Point of care diagnostic systems Systems and methods for medical diagnosis or risk assessment for a patient are provided. These systems and methods are designed to be employed at the point of care, such as in emergency rooms and operating rooms, or in any situation in which a rapid and accurate res... | 09/18/2007 |
| 7270995 | Analyzing device The present invention is an analytical device which comprises a porous piece assembly consisting of a liquid reagent-receiving porous piece (1), a labeled substance-retaining piece (2), a test piece (3) comprising a detection site (4) and... | 09/18/2007 |
| 7270959 | Specimen collection container The present invention recognizes that sample handling devices, particularly those used for testing for substances of abuse, do not allow for a separation of the bulk sample from a sample thereof to be tested. The present invention provides such a device and methods ... | 09/18/2007 |
| 7264971 | Read-head for optical diagnostic device A readhead for a photometric diagnostic instrument includes a housing adapted for incorporation within the photometric diagnostic instrument, and an elongated sample table operatively engaged with the housing. The sample table is configured to support elongated reag... | 09/04/2007 |
| 7264972 | Method and apparatus for sorting biological cells with a MEMS device A micromechanical actuator for sorting hematopoietic stem cells for use in cancer therapies. The actuator operates by diverting cells into one of a number of possible pathways fabricated in the fabrication substrate of the micromechanical actuator, when fluorescence... | 09/04/2007 |
